Characterization of tumors of jaw:Additive value of contrast enhancement and dual-energy computed tomography

作     者：Deepak Justine Viswanathan Ashu Seith Bhalla Smita Manchanda Ajoy Roychoudhury Deepika Mishra Asit Ranjan Mridha 

作者机构：Department of Radiodiagnosis and Interventional RadiologyAll India Institute of Medical SciencesNew Delhi 110029India Department of Oral and Maxillofacial SurgeryAll India Institute of Medical SciencesNew Delhi 110029India Department of Oral Pathology and MicrobiologyAll India Institute of Medical SciencesNew Delhi 110029India Department of PathologyAll India Institute of Medical SciencesAnsari NagarNew Delhi 110029India 

出 版 物：《World Journal of Radiology》 (世界放射学杂志（英文版）（电子版）)

年 卷 期：2024年第16卷第4期

页      面：82-93页

学科分类：1002[医学-临床医学] 1010[医学-医学技术（可授医学、理学学位）] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Jaw neoplasms Ameloblastomas Dual-energy computed tomography Iodine quantification Mandibular neoplasms Maxillary neoplasms 

摘      要：BACKGROUND Currently,the differentiation of jaw tumors is mainly based on the lesion’s morphology rather than the enhancement characteristics,which are important in the differentiation of neoplasms across the *** is a paucity of literature on the enhancement characteristics of jaw *** is mainly because,even though computed tomography(CT)is used to evaluate these lesions,they are often imaged without intravenous *** study hypothesised that the enhancement characteristics of the solid component of jaw tumors can aid in the differentiation of these lesions in addition to their morphology by dual-energy CT,therefore improving the ability to differentiate between various *** To evaluate the role of contrast enhancement and dual-energy quantitative parameters in CT in the differentiation of jaw *** Fifty-seven patients with jaw tumors underwent contrast-enhanced dual-energy *** analysis of the tumor,including the enhancing solid component,was done,followed by quantitative analysis of iodine concentration(IC),water concentration(WC),HU,and normalized *** study population was divided into four subgroups based on histopathological analysis-central giant cell granuloma(CGCG),ameloblastoma,odontogenic keratocyst(OKC),and other jaw tumors.A one-way ANOVA test for parametric variables and the Kruskal-Wallis test for nonparametric variables were *** significant differences were found,a series of independent t-tests or Mann-Whitney U tests were *** Ameloblastoma was the most common pathology(n=20),followed by CGCG(n=11)and *** showed a higher mean concentration of all quantitative parameters than ameloblastomas(P0.05).An IC threshold of 31.35×100μg/cm^(3) had the maximum sensitivity(81.8%)and specificity(65%).Between ameloblastomas and OKC,the former showed a higher mean concentration of all quantitative parameters(P0.001),however when comparing unilocular ameloblastomas with OKCs,the latter showed