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Determination of the time of refractive stability after uneventful phacoemulsification in Indian eyes

World Journal of Experimental Medicine 2024年第2期14卷 89-96页

作者： ashok kumar nanda Bijnya Birajita Panda Asish Swain Logesh Balakrishnan Department of Ophthalmology Kar Vision Eye HospitalBhubaneswar 751013OdishaIndia Department of Ophthalmology All India Institute of Medical SciencesBhubaneswar 751019OdishaIndia Department of Optometry Kar Vision Eye HospitalBhubaneswar 751013OdishaIndia Department of Statistics Apollo HospitalsChennai 823104India

BACKGROUND Knowledge about refractive stabilization and the accuracy of postoperative refractive error measurements are crucial for improved patient outcomes after *** guidelines typically recommend waiting 4-6 wk before prescribing corrective *** research focused on identifying factors that influence refractive errors in the early stages of post-cataract surgery,thus contributing to the existing literature on this *** To investigate the time required for refraction stability after uneventful phacoemulsification *** We compared the variation and statistical significance of the difference in spherical,cylindrical components,and the spherical equivalent between the 1-and 6-wk follow-up period in a group of 257 eyes that underwent uneventful phacoemulsification with foldable intraocular lens implantation,all performed by a single experienced *** Wilcoxon-Signed Rank Test was utilized to assess the magnitude of the change and determine its statistical *** refractive stability was defined as the point at which the change in spherical equivalent was within±0.5 dioptres for two consecutive *** The average age of the patients was 64.9±8.9 *** differences observed in both the visits in spherical power(0.1±0.2),cylinder power(0.3±0.4),and spherical equivalent(0.2±0.2)were minimal and not statistically *** majority of eyes(93.4%)achieved refractive stability within 6 wk after the *** cylindrical power differed between age groups at the 6th wk post-operative and the difference was statistically significant(P value 0.013).There were no significant differences in refractive stability when considering sex and axial *** Phacoemulsification with foldable intraocular lens implantation results in no significant changes in refraction for the majority of cases during the 6-wk follow-up ***,a spectacle prescription can be given at the completion of 1 wk.

关键词： Cataract surgery Phacoemulsification Refraction stability Visual acuity Spherical equivalent

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Enhanced Energy Efficient with a Trust Aware in MANET for Real-Time Applications

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Computers, Materials & Continua 2023年第4期75卷 587-607页

作者： M.V.Narayana Vadla Pradeep kumar ashok kumar nanda Hanumantha Rao Jalla Subba Reddy Chavva Department of CSE Guru Nanak Institutions Technical CampusHyderabadRanga Reddy DistrictTelangana501506India Department of CSE B V Raju Institute of TechnologyNarsapurMedakTelangana502313India Department of CSE T.R.R.Government Degree College KandukurKandukurA.P.523105India Department of IT VFST&Research(Deemed to be University)VadlamudiA.P.522213India

Mobile ad hoc networks (MANETs) are subjected to attack detectionfor transmitting and creating new messages or existing message *** attacker on another node evaluates the forging activity in themessage directly or indirectly. Every node sends short packets in a MANETenvironment with its identifier, location on the map, and time through *** attackers on the network broadcast the warning message usingfaked coordinates, providing the appearance of a network collision. Similarly,MANET degrades the channel utilization performance. Performancehighly affects network performance through security algorithms. This paperdeveloped a trust management technique called Enhanced Beacon TrustManagement with Hybrid Optimization (EBTM-Hyopt) for efficient clusterhead selection and malicious node detection. It tries to build trust amongconnected nodes and may improve security by requiring every participatingnode to develop and distribute genuine, accurate, and trustworthy materialacross the network. Specifically, optimized cluster head election is done periodicallyto reduce and balance the energy consumption to improve the lifetimenetwork. The cluster head election optimization is based on hybridizingParticle Swarm Optimization (PSO) and Gravitational Search OptimizationAlgorithm (GSOA) concepts to enable and ensure reliable routing. Simulationresults show that the proposed EBTM-HYOPT outperforms the state-of-thearttrust model in terms of 297.99 kbps of throughput, 46.34% of PDR, 13%of energy consumption, 165.6 kbps of packet loss, 67.49% of end-to-end delay,and 16.34% of packet length.

关键词： MANET malicious nodes clustering trust management beacon message

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DLMNN Based Heart Disease Prediction with PD-SS Optimization Algorithm

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Intelligent Automation & Soft Computing 2023年第2期35卷 1353-1368页

作者： S.Raghavendra Vasudev Parvati R.Manjula ashok kumar nanda Ruby Singh D.Lakshmi S.Velmurugan Department of Information and Communication Technology Manipal Institute of TechnologyManipal Academy of Higher EducationManipal576104India Department of Information Science and Engineering SDM College of Engineering and TechnologyDharwad580002India Department of Computer Science and Engineering School of ComputingSRM Institute of Science and TechnologyKattankulathurChennai603203India Department of Computer Science and Engineering B.V Raju Institute of TechnologyTelangana502313India Faculty of Engineering and Technology SRM Institute of Science and TechnologyNCR CampusUttar Prasesh201204India School of Computing Science and Engineering VIT Bhopal UniversityMadhya Pradesh466114India Department of Computer Science and Engineering Vel Tech Multi Tech Dr.Rangarajan Dr.Sakunthala Engineering CollegeChennai600062India

In contemporary medicine,cardiovascular disease is a major public health *** diseases are one of the leading causes of death *** are classiﬁed as vascular,ischemic,or *** information contained in patients’Electronic Health Records(EHR)enables clin-icians to identify and monitor heart *** failure rates have risen drama-tically in recent years as a result of changes in modern *** diseases are becoming more prevalent in today’s medical *** year,a substantial number of people die as a result of cardiac *** primary cause of these deaths is the improper use of pharmaceuticals without the supervision of a physician and the late detection of *** improve the efﬁciency of the classiﬁcation algo-rithms,we construct a data pre-processing stage using feature ***-ments using unidirectional and bidirectional neural network models found that a Deep Learning Modiﬁed Neural Network(DLMNN)model combined with the Pet Dog-Smell Sensing(PD-SS)algorithm predicted the highest classiﬁcation performance on the UCI Machine Learning Heart Disease *** DLMNN-based PDSS achieved an accuracy of 94.21%,an F-score of 92.38%,a recall of 94.62%,and a precision of 93.86%.These results are competitive and promising for a heart disease *** demonstrated that a DLMNN framework based on deep models may be used to solve the categorization problem for an unbalanced heart disease *** proposed approach can result in exceptionally accurate models that can be utilized to analyze and diagnose clinical real-world data.

关键词： Machine learning random forest coronary heart disease cardiovascular optimization algorithm

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Noscapine shows antimalarial activity against Plasmodium falciparum 3D7,its clinical isolate Pf140/SS,and Plasmodium berghei ANKA

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Asian Pacific Journal of Tropical Biomedicine 2024年第8期14卷 350-358页

作者： Swaraj kumar Babu Sameer Maharana Satyaranjan Chhatria Dibya Ranjan Sahoo Ashirbad nanda Satish Kanhar Prativa KBehera Sanjib Mohanty Pradeep kumar Naik Praveen Kishore Sahu Centre of Excellence in Natural Products and Therapeutics Department of Biotechnology and BioinformaticsSambalpur UniversityJyoti ViharSambalpur OdishaIndia Department of Molecular Biology and Infectious Diseases Community Welfare Society HospitalRourkelaOdishaIndia Molecular&Immunology Laboratory Infectious Disease Biology UnitIspat General HospitalRourkelaOdishaIndia Department of Pharmacy Centurion University of Technology and ManagementBhubaneswarOdishaIndia

Objective:To evaluate the antimalarial activity of noscapine against Plasmodium falciparum 3D7 strain(Pf3D7),its clinical isolate(Pf140/SS),and Plasmodium berghei ANKA(PbA).Methods:Using ring-stage survival assay,phenotypic assessments,and SYBR-green-based fluorescence assay,the antimalarial activities of noscapine were assessed compared with dihydroartemisinin(DHA)in in vivo and in vitro *** addition,hemolysis and cytotoxicity tests were carried out to evaluate its ***-PCR assay was also conducted to determine the effect of noscapine on papain-like cysteine protease Plasmodium falciparum falcipain-2(PfFP-2).Results:The antimalarial efficacy of noscapine against Pf3D7 and Pf140/SS was comparable to DHA,with IC50 values of(7.68±0.88)and(5.57±0.74)nM/mL,respectively,and>95%inhibition of PbA infected *** also showed a safe profile,as evidenced by low hemolysis and cytotoxicity even at high ***,PfFP-2 expression was significantly inhibited in both noscapine-treated Pf3D7 and Pf140/SS(P<0.01).Conclusions:Noscapine has antimalarial properties comparable to standard antimalarial DHA with better safety profiles,which may be further explored as a therapeutic candidate for the treatment of malaria.

关键词： Malaria Plasmodium falciparum Plasmodium berghei Noscapine Antimalarial Dihydroartemisinin Cytotoxicity Falcipain-2

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Mitigating Carbon Emissions:A Comprehensive Analysis of Transitioning to Hydrogen-Powered Plants in Japan’s Energy Landscape Post-Fukushima

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Energy Engineering 2024年第5期121卷 1143-1159页

作者： Nugroho Agung Pambudi Andrew Chapman Alfan Sarifudin Desita Kamila Ulfa Iksan Riva nanda Department of Mechanical Engineering Education Universitas Sebelas MaretSukoharjo57161Indonesia International Institute for Carbon-Neutral Reserch(WPI-I2CNER) Kyushu UniversityFukuoka819-0395Japan Postgraduate of Mechanical Engineering Universitas Sebelas MaretSurakarta57126Indonesia Energy and Society Laboratory Department of Mechanical Engineering EducationUniversitas Sebelas MaretSukoharjo57161Indonesia Department of Metallurgical and Material Engineering Universitas IndonesiaDepok16424Indonesia

One of the impacts of the Fukushima disaster was the shutdown of all nuclear power plants in Japan,reaching zero production in *** response,the country started importing more fossil energy including coal,oil,and natural gas to fill the energy ***,this led to a significant increase in carbon emissions,hindering the efforts to reduce its carbon *** the current situation,Japan is actively working to balance its energy requirements with environmental considerations,including the utilization of hydrogen ***,this paper aims to explore the feasibility and implications of using hydrogen power plants as a means to reduce emissions,and this analysis will be conducted using the energy modeling of the MARKAL-TIMES Japan *** hydrogen scenario(HS)is assumed with the extensive integration of hydrogen into the power generation sector,supported by a hydrogen import ***,this scenario will be compared with the Business as Usual(BAU)*** results showed that the generation capacities of the BAU and HS scenarios have significantly different primary energy *** BAU scenario is highly dependent on fossil fuels,while the HS scenario integrates hydrogen contribution along with an increase in renewable energy,reaching a peak contribution of 2,160 PJ in *** the HS scenario,the target of reducing CO_(2) emissions by 80%is achieved through significant hydrogen *** 2050,the total CO_(2) emissions are estimated to be 939 million tons for the BAU scenario and 261 million tons for the Hydrogen *** addition,the contribution of hydrogen to electricity generation is expected to be 153 TWh,smaller than PV and wind power.

关键词： Business as usual(BAU)scenario hydrogen scenario CO_(2)emissions power generation sector

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Analysis of the Fertilizing and Bioremediation Potential of Leaf Litter Compost Amendment in Different Soils through Indexing Method

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Journal of Environmental Protection 2024年第3期15卷 265-297页

作者： Sophayo Mahongnao Pooja Sharma Arif Ahamad Sarita nanda Department of Biochemistry Daulat Ram College University of Delhi New Delhi India Department of Environmental Science Jamia Millia Islamia University New Delhi India

This research study explored the efficacy of leaf litter compost as a sustainable soil amendment with the objective of promoting soil health and mitigating the accumulation of potentially toxic elements. The investigation encompassed the impact of various organic compost amendments, including leaf compost, cow dung manure, kitchen waste compost, municipal organic waste compost, and vermicompost. The study employed Inductively Coupled Plasma Mass Spectrometry (ICP-MS) to evaluate soil nutrient levels and concentrations of Potentially Toxic Elements (PTEs) such as arsenic, chromium, cadmium, mercury, lead, nickel, and lithium. The fertilization and bioremediation potential of these compost amendments are quantified using an indexing method. Results indicated a substantial increase in overall nutrient levels (carbon, nitrogen, phosphorus, potassium, and sulfur) in soils treated with leaf compost and other organic composts. Fertility indices (FI) are notably higher in compost-amended soils (ranging from 2.667 to 3.938) compared to those amended with chemical fertilizers (ranging from 2.250 to 2.813) across all soil samples. Furthermore, the mean concentrations of PTEs were significantly lower in soils treated with leaf compost and other organic compost amendments compared to those treated with chemical fertilizers amendments. The assessment through the indexing method revealed a high clean index (CI) for leaf compost amendment (ranging from 3.407 to 3.58), whereas the chemical fertilizer amendment exhibits a relatively lower CI (ranging from 2.78 to 3.20). Consequently, leaf compost and other organic composts exhibit the potential to enhance sustainable productivity, promoting soil health and environmental safety by improving nutrient levels and remediating potentially toxic elements in the soil.

关键词： Bio-Compost Soil Fertility Potentially Toxic Elements Bioremediation

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Parents’s knowledge and awareness about hepatitis B can influence the vaccination of their children

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World Journal of Virology 2024年第2期13卷 96-106页

作者： nanda Chhavi Geetika Srivastava Mariya Waseem Abhishek Yadav Surender Singh Rajani Singh Amit Goel Department of Paediatrics Era’s Lucknow Medical CollegeLucknow 226003Uttar PradeshIndia Medical Consultant National Disease Control ProgramNational Health MissionLucknow 226003Uttar PradeshIndia Department of Hepatology Sanjay Gandhi Postgraduate Institute of Medical SciencesLucknow 226014Uttar PradeshIndia

BACKGROUND Birth-dose(Hep-BD)followed by three additional doses(Hep-B3)of hepatitis B virus(HBV)vaccine are key to eliminating HBV by ***,Hep-BD and Hep-B3 coverage in our country is *** To studied the parent’s knowledge and awareness about HBV infection,its prevention,consequences and *** Parents of 6 months to 8 years old children were interviewed to assess their knowledge&awareness about hepatitis B,its transmission,prevention,illness caused by this,and *** close-ended questions were admini-stered,and responses were recorded as‘yes’,‘no’,or‘not sure’.HBV knowledge score was calculated based on the sum of correct *** correct response scored one point and incorrect,missing or‘not sure’responses received no *** data are presented as number(%)and numerical data are expressed as *** were compared using Chi2 tests and level of significance was kept as P<*** Parents(58.3%mothers)of 384 children(89.9%age<5 years;82%age-appropriately vaccinated)were *** hundred and twenty-two(83.9%)children were Hep-B3 vaccinated.94.3%,87.5%,and 29.2%parents knew about polio,tetanus,and hepatitis B ***,41.2%,15.8%,and 23%parents knew about hepatitis B transmission,consequences of infection,and prevention *** 7.6%parents knew about three-dose schedule of hepatitis B *** 23%parents believed that vaccine could prevent HBV,15.7%knew that HBV affects *** of Hep-B3 vaccinated children were significantly more aware about HBV than the parents of unvaccinated children(P<0.05 for 17/18 questions).CONCLUSION The knowledge and awareness among the parents about hepatitis B is *** Increasing knowledge/awareness about HBV among parents may improve Hep-B3 vaccination coverage.

关键词： Hepatitis B Viral hepatitis Cirrhosis Hepatocellular carcinoma Hepatotropic viruses Transfusion transmitted infection Mother to child transmission

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A state-of-the-art review of solar passive building system for heating or cooling purpose

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Frontiers in Energy 2016年第3期10卷 347-354页

作者： Arun kumar nanda C K PANIGRAHI Birla Institute of Technology Mesra Ranchiranchi 835215 India School of Electrical Engineering Kalinga Institute of Industrial Technology Bhubaneswar 751024 India

The major portion of energy in a building is consumed by heating, ventilating, and air-conditioning （HVAC）. The traditional heating and cooling systems contribute greatly to the emission of greenhouse gases, especially carbon dioxide. Four different ways, i.e., Trombe wall, solar chimney, unglazed transpired solar facade, and solar roof, are adopted for solar heating. Similarly, two major ways, i.e., evaporative cooling and building integrated evaporative cooling are adopted for cooling of the building. Therefore, an attempt has been made in this paper to compile the developments of solar heating and cooling technologies in a building.

关键词： HVAC heating cooling solar heating carbondioxide (CO2) emissions

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In vivo immunostimulatory effect of the amoebocyte lysate and plasma of Asian horseshoe crab,Tachypleus gigas in a piscine model

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Marine Life Science & Technology 2021年第3期3卷 355-362页

作者： Sukanta kumar Nayak Pramod kumar nanda Priyabrat Swain Department of Biotechnology Maharaja Sriram Chandra Bhanja Deo University(Erstwhile North Orissa University)Odisha757003India ICAR-Indian Veterinary Research Institute Eastern Regional StationKolkata700037India Fish Health Management Division Central Institute of Freshwater AquacultureBhubaneswar751002India

Antimicrobial proteins/peptides are becoming a new generation of immunostimulants for prevention and disease control in human and animals,including aquatic *** the haemolymph of horseshoe crabs(Tachypleus)contains broad ranges of bioactive compounds,we have explored the in vivo immunostimulating potential of amoebocyte lysate and plasma using a fish *** major carp,Labeo rohita,yearlings were injected intraperitoneally with two doses of lysate and plasma at 50 and 100µg protein per *** abnormalities and/or mortalities were recorded in any *** injected with 50µg lysate and 100µg plasma protein showed significant enhancement(P0.01)in any *** the contrary,a significantly high hemolysin titre was recorded in fish that received 100µg plasma *** challenge with Aeromonas hydrophila,both lysate and plasma protein(s)cross protected the fish after 30 *** highest survival(50%)was recorded in group injected with 50µg lysate protein,followed by 45%in both 100µg lysate and plasma protein injected groups.

关键词： Amoebocyte lysate Immunostimulatory Labeo rohita Plasma Tachypleus gigas

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Microsponges for dermatological applications:Perspectives and challenges

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Asian Journal of Pharmaceutical Sciences 2020年第3期15卷 273-291页

作者： Sheefali Mahant Sunil kumar Sanju nanda Rekha Rao Department of Pharmaceutical Sciences Maharshi Dayanand UniversityRohtak 124001India Department of Pharmaceutical Sciences Guru Jambheshwar University of Science and TechnologyHisar 125001India

Dermatological disorders have a huge psychosocial impact, causing significant impairment of patient’s life. Topical therapy plays a pivotal role in management of such *** topical delivery systems result in overmedication/undermedication, leading to adverse effects and reduction in therapeutic efficacy. Consequently, researchers have been striving towards the development of alternative delivery systems for dermatological applications. In the last decade, microsponges emerged as an attractive option for topical delivery. Their characteristic particle size offers enhanced benefits, making them superior to the contemporary microcarriers. The present review furnishes a comprehensive account of state of the art, important factors affecting the performance and mechanism of drug release from topically applied microsponges, along with characterization techniques. Further, a list of marketed products and their applications for common dermatological disorders has been presented. All in all, this paper is an attempt to lay a bibliographic foundation for researchers working in this field and foster further investigations in this arena.

关键词： Skin Polymers Drug release Dermatology Safety aspects Stability

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