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MARS and RNAcmap3:The Master Database of All Possible RNA Sequences Integrated with RNAcmap for RNA Homology Search

Genomics, Proteomics & Bioinformatics 2024年第1期22卷 143-150页

作者： ke Chen Thomas Litfin Jaswinder Singh Jian Zhan Yaoqi Zhou Institute of Systems and Physical Biology Shenzhen Bay LaboratoryShenzhen 518055China Peking University Shenzhen Graduate School Shenzhen 518055China University of Science and Technology of China Hefei 230026China Suzhou Institute for Advanced Research University of Science and Technology of ChinaSuzhou 215123China Institute for Glycomics Griffith UniversitySouthportQLD 4222Australia

sequences found in the huge,integrated database of protein sequences(Big Fantastic Database).In contrast,the existing nucleotide databases were not consolidated to facilitate wider and deeper homology ***,we built a comprehensive database by incorporating the non-coding RNA(ncRNA)sequences from RNAcentral,the transcriptome assembly and metagenome assembly from metagenomics RAST(MG-RAST),the genomic sequences from Genome Warehouse(GWH),and the genomic sequences from MGnify,in addition to the nucleotide(nt)database and its subsets in National Center of Biotechnology Information(NCBI).The resulting Master database of All possible RNA sequences(MARS)is 20-fold larger than NCBI’s nt database or 60-fold larger than *** new dataset along with a new split-search strategy allows a substantial improvement in homology search over existing state-of-the-art *** also yields more accurate and more sensitive multiple sequence alignments(MSAs)than manually curated MSAs from Rfam for the majority of structured RNAs mapped to *** results indicate that MARS coupled with the fully automatic homology search tool RNAcmap will be useful for improved structural and functional inference of ncRNAs and RNA language models based on *** is accessible at https://***/omix/release/OMIX003037,and RNAcmap3 is accessible at http://***/download/.

关键词： RNA sequence database Homology search Secondary structure MARS RNAcmap3

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Analytical Modeling of Disaster-induced Load Loss for Preventive Allocation of Mobile Power Sources in Urban Power Networks

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Journal of Modern Power Systems and Clean Energy 2024年第4期12卷 1063-1073页

作者： Zhuorong Wang Qingxin Shi ke Fan Haiteng Han Wenxia Liu Fangxing Li School of Electrical&Electronics Engineering North China Electric Power UniversityBeijing 102206China College of Energy and Electrical Engineering Hohai UniversityNanjing 211100China The University of Tennessee Knoxville TN 37996USA

Continuous power supply of urban power networks(UPNs)is quite essential for the public security of a city be-cause the UPN acts as the basis for other infrastructure *** recent years,UPN is threatened by extreme weather *** accurate modeling of load loss risk under extreme weather is quite essential for the preventive action of ***-sidering the forecast intensity of a typhoon disaster,this paper proposes analytical modeling of disaster-induced load loss for preventive allocation of mobile power sources(MPSs)in ***,based on the topological structure and fragility model of overhead lines and substations,we establish an analytical load loss model of multi-voltage-level UPN to quantify the spatial dis-tribution of disaster-induced load loss at the substation ***,according to the projected load loss distribution,a pre-ventive allocation method of MPS is proposed,which makes the best use of MPS and dispatches the limited power supply to most vulnerable areas in the ***,the proposed meth-od is validated by the case study of a practical UPN in China.

关键词： Load loss fragility model pre-disaster allocation mobile power source urban power network

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Optimization of ferroelectricity and endurance of hafnium zirconium oxide thin films by controlling element inhomogeneity

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Journal of Advanced Ceramics 2024年第7期13卷 1023-1031页

作者： Fei Yan ke Cao Yang Chen Jiajia Liao Min Liao Yichun Zhou Shaanxi key Laboratory of High-Orbits-Electron Materials and Protection Technology for Aerospace School of Advanced Materials and NanotechnologyXidian UniversityXi’an 710126China Xi’an key Laboratory of Reconfigurable Chip and Materials School of Advanced Materials and NanotechnologyXidian UniversityXi’an 710126China Frontier Research Center of Thin Films and Coatings for Device Applications Academy of Advanced Interdisciplinary ResearchXidian UniversityXi’an 710126China

Ferroelectric thin films based on HfO_(2) have garnered increasing attention worldwide,primarily due to their remarkable compatibility with silicon and scalability,in contrast to traditional perovskite-structured ferroelectric ***,significant challenges remain in their widespread commercial utilization,particularly concerning their notable wake-up effect and limited *** address these challenges,we propose a novel strategy involving the inhomogeneous distribution of Hf/Zr elements within thin films and explore its effects on the ferroelectricity and endurance of Hf_(0.5)Zr_(0.5)O_(2) thin *** techniques such as grazing incidence X-ray diffraction,transmission electron microscopy,and piezoresponse force microscopy,we investigated the structural characteristics and domain switching behaviors of these *** experimental results indicate that the inhomogeneous distribution of Hf/Zr contributes to improving the frequency stability and endurance while maintaining a large remnant polarization in Hf_(0.5)Zr_(0.5)O_(2) ferroelectric thin *** adjusting the distribution of Zr/Hf within the Hf_(0.5)Zr_(0.5)O_(2) thin films,significant enhancements in the remnant polarization(2P_(r)>35μC/cm2)and endurance(>109)along with a reduced coercive voltage can be ***,the fabricated ferroelectric thin films also exhibit high dielectric tunability(≥26%)under a low operating voltage of 2.5 V,whether in the wake-up state or *** study offers a promising approach to optimize both the ferroelectricity and endurance of HfO_(2)-based thin films.

关键词： ferroelectric capacitors thin films ferroelectricity hafnium zirconium oxide

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Design,modeling and experimental investigation of a novel solar sail with high area-to-mass ratios for efficient solar sailing

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Chinese Journal of Aeronautics 2024年第10期37卷 234-248页

作者： Zhongjing REN Chengyang LI ke WU Ziran WANG Haipeng WANG Peng YAN key Laboratory of High-efficiency and Clean Mechanical Manufacture(Ministry of Education) School of Mechanical EngineeringShandong UniversityJinan 250061China China Manned Space Agency Beijing 100071China

Solar sailing is a promising propellant-free approach to propelling spacecraft in ***,the propelling efficiency of conventional solar sail spacecraft is limited by their areato-mass *** paper proposes a novel design of micro solar sails with area-to-mass ratios above 100 m2/kg for next-generation chip-scale *** thin films developed by Microelectromechanical Systems(MEMS)technologies were patterned into grid microstructures,and theoretical analysis of a sail prototype was *** electro-thermal and thermo-mechanical models of the solar sail in geospace were established by taking effects of Joule heating,solar radiation,and thermal re-emission into consideration,enabling rapid prediction of its threedimensional(3-D)reconfiguration from the as-released two-dimensional(2-D)*** of the ChipSail’s acceleration arising from the sail’s morphing was also analytically *** and characterization of the sail prototype made of multiple Al/Ni50Ti50 bilayer beams were ***-situ SEM imaging of the sail prototype in vacuum chamber witnessed an active and continuous 3-D reconfiguration under Joule heating,and over 90deformation was detected by applying a DC voltage of 0.078 *** and experimental work on the solar sail with at least 10 times higher area-to-mass ratios than conventional ones will lay a solid foundation for efficient solar sailing.

关键词： Solar sails Solar sailing High area-to-mass ratios Solar radiation pressure ChipSail

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Numerical Simulation on Radon Retardation Behavior of Covering Floats in Radon-Containing Water

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Biomedical and Environmental Sciences 2024年第4期37卷 406-417页

作者： LIU Shu Yuan ZHANG Li YE Yong Jun DING Ku ke National Institute for Radiological Protection Chinese Center for Disease Control and PreventionBeijing 100088China Office for Public Health Management Chinese Center for Disease Control and PreventionBeijing 102206China key Discipline Laboratory for National Defense for Biotechnology in Uranium Mining and Hydrometallurgy University of South ChinaHengyang 421001HunanChina

Objective This study aimed to efficiently reduce the release of radon from water bodies to protect the *** Based on the sizes of the experimental setup and modular float,computational fluid dynamics(CFD)was used to assess the impact of the area coverage rate,immersion depth,diffusion coefficient,and radon transfer velocity at the gas–liquid interface on radon migration and exhalation of radon-containing *** on the numerical simulation results,an estimation model for the radon retardation rate was *** effectiveness of the CFD simulation was evaluated by comparing the experimental and simulated variation values of the radon retardation rate with the coverage area *** The effect of radon transfer velocity on radon retardation in water bodies was minor and insignificant according to the appropriate value;therefore,an estimation model of the radon retardation rate of the coverage of a radon-containing water body was constructed using the synergistic impacts of three factors:area coverage rate,immersion depth,and diffusion *** deviation between the experimental and simulated results was<4.3%.Conclusion Based on the numerical simulation conditions,an estimation model of the radon retardation rate of covering floats in water bodies under the synergistic effect of multiple factors was obtained,which provides a reference for designing covering floats for radon retardation in radoncontaining water.

关键词： Radon-containing water Radon retardation rate CFD Coverage experiment Optimized design

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Observation of ballistic-diffusive thermal transport in GaN transistors using thermoreflectance thermal imaging

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Rare Metals 2024年第1期43卷 389-394页

作者： Zhi-ke Liu Yang Shen Han-Ling Li Bing-Yang Cao key Laboratory for Thermal Science and Power Engineering of Ministry of Education Department of Engineering MechanicsTsinghua UniversityBeijing 100084China

To develop effective thermal management strategies for gallium-nitride (GaN) transistors, it is essential to accurately predict the device junction temperature. Since the width of the heat generation in the devices is comparable to phonon mean free paths (MFPs) of GaN, phonon ballistic transport exists and can significantly affect the heat transport process.

关键词： temperature. transistors GaN

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Interface strengthening for thermal sprayed WC-10Co4Cr coating subjected to pulsed magnetic treatment

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Rare Metals 2024年第2期43卷 780-795页

作者： Cheng-Kai Qian Qu Liu Heng Wang ke-Jian Li Zhi-Peng Cai Department of Mechanical Engineering Tsinghua UniversityBeijing100084China Tianjin Research Institute for Advanced Equipment Tsinghua UniversityTianjin300304China State key Laboratory of Tribology in Advanced Equipment Tsinghua UniversityBeijing100084China

The reliability of the coated industry components demands ideal fatigue properties of the coating,and it is mainly determined by the performance of the *** this study,pulsed magnetic treatment(PMT)was applied to the thermal sprayed WC-10Co4Cr coating,and the fatigue lifetime of the coated bolt increased by 219.82%under an imitation of the operating mode *** tests further proved that both the adhesion and cohesion strength were improved after PMT,and they benefit from the interface strengthening *** formation of coherent WC/Co interfaces was characterized by in-situ transmission electron microscopy(TEM),and the molecular dynamic simulations indicate that the work of separation of these interfaces is much higher than the original disordered *** stress was relaxed and distributed more homogeneously after PMT,and it mainly contributes to the coating/substrate *** work provides a new post-treatment method focusing on the interfaces in the WC-based coating and gives insight into its mechanism so that it is hopeful to be applied to other kinds of coatings.

关键词： Cemented carbide coating Pulsed magnetic treatment Interface strengthening Fatigue properties Adhesion strength

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On the Quantum Cohomology of Blow-ups of Four-dimensional Quadrics

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Acta Mathematica Sinica,English Series 2024年第1期40卷 313-328页

作者： Jian Xun HU Hua Zhong ke Chang Zheng LI Lei SONG School of Mathematics Sun Yat-sen UniversityGuangzhou 510275P.R.China

We propose a conjecture relevant to Galkin’s lower bound conjecture,and verify it for the blow-ups of a four-dimensional quadric at a point or along a projective *** also show that Conjecture O holds in these two cases.

关键词： Quantum cohomology blow-up quadric hypersurface

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A Novel Approach for Trajectory Tracking Control of an Under-Actuated Quad-Rotor UAV

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IEEE/CAA Journal of Automatica Sinica 2024年第9期11卷 2030-2032页

作者： ke Shao Kang Huang Shengchao Zhen Hao Sun Rongrong Yu School of Civil Aviation Northwestern Polytechnical UniversityXi’an 710072 School of Mechanical Engineering Hefei University of TechnologyHefei 230009China

Dear Editor,This letter presents a novel Udwadia-Kalaba(U-K)approach for the trajectory tracking control of a quad-rotor unmanned aerial vehicle(UAV).Compared to conventional control approaches,the desired trajectorie... 详细信息

关键词： letter desired constraints

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Nano-sized stationary phase packings retained by single-particle frit for microchip liquid chromatography

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Chinese Chemical Letters 2024年第4期35卷 486-489页

作者： Wangyan Hu ke Li Xiangnan Dou Ning Li Xiayan Wang Center Excellence for Environmental Safety and Biological Effects Beijing Key Laboratory for Green Catalysis and SeparationDepartment of ChemistryBeijing University of TechnologyBeijing 100124China Center for Environmental Metrology National Institute of MetrologyBeijing 100029China

Modern chromatography is increasingly focused on miniaturization and integration. Compared to conventional liquid chromatography, microfluidic chip liquid chromatography(microchip-LC) has the potential due to its zero-dead volume connection and ease of integration. Nano-sized packings have the potential to significantly enhance separation performance in microchip-LC. However, their application has been hindered by packing difficulties. This study presents a method for packing nano-sized silica particles into a microchannel as the stationary phase. The microchip-LC packed column was prepared by combining the weir and the porous silica single-particle as frit to retain the packing particles. A surface tensionbased single-particle picking technique was established to insert porous single-particle frit into glass microchannels. Additionally, we developed a slurry packing method that utilizes air pressure to inject nano-sized packing into the microchannel. Pressure-driven chromatographic separation was performed using this nano-packed column integrated into a glass microchip. The mixture of four PAHs was successfully separated within just 8 min using a 5 mm separation channel length, achieving high theoretical plates(10~6plates/m). Overall, these findings demonstrate the potential of utilizing nano-sized packings for enhancing chromatographic performance in microchip systems.

关键词： Nano-size packing Single-particle frit Packed column Microchip LC Chromatographic separation

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