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Neuroscience Bulletin 2014年第6期30卷 956-966页

作者： arne Raasakka Petri Kursula Department of Biochemistry and Biocenter Oulu University of OuluOuluFinland Department of Chemistry University of HamburgHamburgGermany

The membrane-anchored myelin enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase（CNPase） was discovered in the early 1960 s and has since then troubled scientists with its peculiar catalytic activity and high expression levels in the central nervous system. Despite decades of research, the actual physiological relevance of CNPase has only recently begun to unravel. In addition to a role in myelination, CNPase is also involved in local adenosine production in traumatic brain injury and possibly has a regulatory function in mitochondrial membrane permeabilization. Although research focusing on the CNPase phosphodiesterase activity has been helpful, several open questions concerning the protein function in vivo remain unanswered. This review is focused on past research on CNPase, especially in the fields of structural biology and enzymology, and outlines the current understanding regarding the biochemical and physiological significance of CNPase, providing ideas and directions for future research.

关键词： 2′,3′-cyclic nucleotide 3′-phosphodiesterase calmodulin central nervous system cytoskeleton myelin proteins RNA

Methods of modeling relative growth rate

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Forest Ecosystems 2015年第2期2卷 82-90页

作者： arne Pommerening Anders Muszta Department of Forest Resource Management Faculty of Forest SciencesSwedish University of Agricultural Sciences SLU

Background： Analysing and modelling plant growth is an important interdisciplinary field of plant science. The use of relative growth rates, involving the analysis of plant growth relative to plant size, has more or less independently emerged in different research groups and at different times and has provided powerful tools for assessing the growth performance and growth efficiency of plants and plant populations. In this paper, we explore how these isolated methods can be combined to form a consistent methodology for modelling relative growth rates. Methods： We review and combine existing methods of analysing and modelling relative growth rates and apply a combination of methods to Sitka spruce （Piceo sitchensis （Bong.） Carr.） stem-analysis data from North Wales （UK） and British Douglas fir （Pseudotsugd menziesii （Mirb.） Franco） yield table data. Results： The results indicate that, by combining the approaches of different plant-growth analysis laboratories and using them simultaneously, we can advance and standardise the concept of relative plant growth. Particularly the growth multiplier plays an important role in modelling relative growth rates. Another useful technique has been the recent introduction of size-standardised relative growth rates. Conclusions： Modelling relative growth rates mainly serves two purposes, 1） an improved analysis of growth performance and efficiency and 2） the prediction of future or past growth rates. This makes the concept of relative growth ideally suited to growth reconstruction as required in dendrochronology, climate change and forest decline research and for interdisciplinary research projects beyond the realm of plant science.

关键词： Growth efficiency Growth coefficient/multiplier Chapman-Richards growth model Standardisation Simultaneous estimations

Early Warning Smartphone Diagnostics for Water Security and Analysis Using Real-Time pH Mapping

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Photonic Sensors 2015年第4期5卷 289-297页

作者： Md. Arafat HOSSAIN John CANNING Sandra ast Peter J. RUTLEDGE Abbas JAMALIPOUR interdisciplinary Photonics Laboratories (iPL) School of Chemistry The University of Sydney NSW 2006 Australia School of Chemistry The University of Sydney NSW 2006 Australia Wireless Networking Group (WING) School of Electrical and Information Engineering The University of Sydney NSW2006 Australia

Early detection of environmental disruption, unintentional or otherwise, is increasingly desired to ensure hazard minimization in many settings. Here, using a field-portable, smartphone fluorimeter to assess water quality based on the pH response of a designer probe, a map of pH of public tap water sites has been obtained. A custom designed Android application digitally processed and mapped the results utilizing the global positioning system （GPS） service of the smartphone. The map generated indicates no disruption in pH for all sites measured, and all the data are assessed to fall inside the upper limit of local government regulations, consistent with authority reported measurements. This implementation demonstrates a new security concept： network environmental forensics utilizing the potential of novel smartgrid analysis with wireless sensors for the detection of potential disruption to water quality at any point in the city. This concept is applicable across all smartgrid strategies within the next generation of the Internet of Things and can be extended on national and global scales to address a range of target analytes, both chemical and biological.

关键词： Lab-in-a-phone Intemet of Things optical sensing and sensor smartphone sensor photonic sensor fluorescence water security

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《江苏省对口支援新疆建设志》编纂始末

江苏地方志 2024年第1期 93-95页

作者：江苏援疆志编辑室江苏省地方志办公室江苏南京210004

寒来暑往,历经六载,在江苏省委、省政府高度重视和省政府办公厅指导推动下,在省各有关部门、相关设区市政府,省对口支援新疆伊犁州、克州前方指挥部和各前方工作组等大力支持下,在具体参与编纂工作的200余位同志共同努力下,由省地方志... 详细信息

寒来暑往,历经六载,在江苏省委、省政府高度重视和省政府办公厅指导推动下,在省各有关部门、相关设区市政府,省对口支援新疆伊犁州、克州前方指挥部和各前方工作组等大力支持下,在具体参与编纂工作的200余位同志共同努力下,由省地方志办公室组织编纂的《江苏省对口支援新疆建设志》终于付梓。

关键词：地方志办公室新疆伊犁州编纂工作对口支援设区市编纂始末江苏省工作组

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Mitigating self-excited flame pulsating and thermoacoustic oscillations using perforated liners

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Science Bulletin 2019年第13期64卷 941-952页

作者： Dan Zhao Ephraim Gutmark arne Reinecke Department of Mechanical Engineering College of EngineeringUniversity of CanterburyChristchurch 8140New Zealand Department of Aerospace Engineering and Engineering Mechanics University of CincinnatiCincinnatiOH 45221-0070USA School of Mechanical and Aerospace Engineering Nanyang Technological UniversitySingapore 639798Singapore

Open-loop control of self-excited flame pulsating oscillations and thermo-acoustic instability is considered in this *** performance of the control strategy is numerically evaluated in a 2 D Rij ke-type combustor with a perfo rated pipe *** is found that approximately 38 dB sound pressure level(SPL)reduction can be achieved by actively tuning the cooling flow through the perforated ***,the vorticity-induced damping performance is contributing to the breaking up of flame-acoustics ***,the shedding of vortices is not uniformly distributed along the perforated *** apply the control strategy in practice and to validate the findings,experimental studies are performed on a customerdesigned Rij ke-type combustor with a perfo rated liner *** mimic practical engines,a cooling flow generated by a centrifugal pump is provided to pass through the perforated *** tuning the cooling flow rate is found to lead to the unstable combustor being successfully *** is red uced by approximately 35 dB at ω1/2π≈245 Hz,and harmonic thermoacoustic modes are completely *** study is conducted by suddenly re moving the perforated pipe *** combustion system is found to be associated with not only classical thermo-acoustic limit cycle oscillations with a dominant mode at 2.45 × 102 Hz,but also beating oscillations at 1.4 × 1 00 *** is revealed that increasing acoustic losses by implementing the perforated pipe is another critical mechanism contributing to attenuating flame pulsating *** present work opens up an applicable means to attenuate both selfexcited high-frequency thermoacoustic and low-frequency flame pulsating oscillations.

关键词： Flame beating Combustion instability Thermo-acoustic instability Thermal-diffusive instability Perforated pipe Acoustic losses

Influence of CaO on damping capacity and mechanical properties of Mg alloy

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中国有色金属学会会刊：英文版 2009年第B9期19卷 76-79页

作者： Dong-In JANG Jin-Kyu LEE Dae-up KIM Shae-K KIM Advanced Material Division Korea Institute of Industrial Technology Hyudai Mobis

For developing cost effective damping Mg alloys with high damping capacity and better mechanical properties, the microstructures, the mechanical properties at room temperature and the damping capacity of Mg alloy adding CaO were investigated and compared with those of K1A alloy. CaO adding into pure Mg maintains the damping capacity and increases the ultimate tensile strength compared with those of pure Mg. Mg-CaO alloy can be regarded as cost-effective damping alloy with high damping and mechanical properties as well as with the advantages of improving oxidation and burning resistances.

关键词：阻尼能力力学性能镁合金氧化钙成本效益微观结构阻尼性能电阻合金

Biliary cholesterol secretion: More than a simple ABC

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World Journal of Gastroenterology 2010年第47期16卷 5936-5945页

作者： arne Dikkers Uwe JF Tietge Department of Pediatrics Center for Liver Digestive and Metabolic DiseasesUniversity Medical Center Groningen University of Groningen

Biliary cholesterol secretion is a process important for 2 major disease complexes, atherosclerotic cardiovascular disease and cholesterol gallstone disease. With respect to cardiovascular disease, biliary cholesterol secretion is regarded as the f inal step for the elimination of cholesterol originating from cholesterol-laden macrophage foam cells in the vessel wall in a pathway named reverse cholesterol transport. On the other hand, cholesterol hypersecretion into the bile is considered the main pathophysiological determinant of cholesterol gallstone formation. This review summarizes current knowledge on the origins of cholesterol secreted into the bile as well as the relevant processes and transporters involved. Next to the established ATP-binding cassette (ABC) transporters mediating the biliary secretion of bile acids (ABCB11), phospholipids (ABCB4) and cholesterol (ABCG5/G8), special attention is given to emerging proteins that modulate or mediate biliary cholesterol secretion. In this regard, the potential impact of the phosphatidylserine flippase ATPase class Ⅰ type 8B member 1, the Niemann Pick C1-like protein 1 that mediatescholesterol absorption and the high density lipoprotein cholesterol uptake receptor, scavenger receptor class B type Ⅰ, is discussed.

关键词： Cholesterol Bile Gallstone Atherosclerosis Reverse cholesterol transport Lipoproteins High density lipoprotein Scavenger receptor class B type Ⅰ

Non-invasive prediction of forthcoming cirrhosis-related complications

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World Journal of Gastroenterology 2014年第10期20卷 2613-2623页

作者： Wonseok Kang Seung up Kim Sang Hoon Ahn Department of Internal Medicine Institute of Gastroenterology Yonsei University College of Medicine Seoul 120-752 South Korea Liver Cirrhosis Clinical Research Center Seoul 120-752 South Korea

In patients with chronic liver diseases,identification of significant liver fibrosis and cirrhosis is essential for determining treatment strategies,assessing therapeutic response,and stratifying long-term *** liver biopsy remains the reference standard for evaluating the extent of liver fibrosis in patients with chronic liver diseases,several non-invasive methods have been developed as alternatives to liver *** of these non-invasive methods have demonstrated clinical accuracy for diagnosing significant fibrosis or cirrhosis in many cross-sectional studies with the histological fibrosis stage as a reference ***,non-invasive methods cannot be fully validated through cross-sectional studies since liver biopsy is not a perfect surrogate endpoint ***,recent studies have focused on assessing the performance of non-invasive methods through longterm,longitudinal,follow-up studies with solid clinical endpoints related to advanced stages of liver fibrosis and *** a result,current view is that these alternative methods can independently predict future cirrhosis-related complications,such as hepatic decompensation,liver failure,hepatocellular carcinoma,or liver-related *** clinical role of non-invasive models seems to be shifting from a simple tool for predicting the extent of fibrosis to a surveillance tool for predicting future liver-related *** this article,we will summarize recent longitudinal studies of non-invasive methods for predicting forthcoming complications related to liver cirrhosis and discuss the clinical value of currently available non-invasive methods based on evidence from the literature.

关键词： Non-invasive model Prediction Cirrhosis Complication Liver-related events

Acute limb ischemia after minimally invasive cardiac surgery using the ProGlide:A case series

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World Journal of Clinical Cases 2022年第35期10卷 13052-13057页

作者： Jonggeun Lee up Huh Seunghwan Song Chung Won Lee Department of Thoracic and Cardiovascular Surgery Pusan National University School of MedicineBiomedical Research InstitutePusan National University HospitalBusan 49241South Korea

BACKGROUND We report two cases of acute femoral artery occlusion following the use of ProGlide in minimally invasive cardiac surgery and insertion of large-bore catheters through the common femoral *** will add to the existing body of literature by highlighting the possible complications associated with the use of ProGlide and reiterate that the use of the sono-guided ProGlide skill will reduce the incidence of these *** SUMMARY A 78-year-old man underwent minimally invasive cardiac surgery for severe aortic valve *** the operation,the puncture site of the common femoral artery was closed using *** next morning,after regaining consciousness,he complained of pain,motor weakness(grade 2),and coldness in the right lower extremity.A 65-year-old man underwent minimally invasive cardiac surgery for a large secundum atrial septal defect(5 cm×5 cm).After the operation,the puncture site of the common femoral artery was closed using *** extubation,the patient complained of paresthesia of the right *** the patients underwent emergency surgery for acute occlusion of the common femoral *** If the sono-guided ProGlide skill is used,complications can be prevented,and ProGlide can be safely used.

关键词： ProGlide Acute common femoral artery occlusion Minimal invasive cardiac surgery Sono-guided Femoral artery stenosis Case report

Global woodland structure from local interactions:new nearest-neighbour functions for understanding the ontogenesis of global forest structure

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Forest Ecosystems 2020年第2期7卷 290-300页

作者： arne Pommerening Hongxiang Wang Zhonghua Zhao Faculty of Forest Sciences Department of Forest Ecology and ManagementSwedish University of Agricultural Sciences SLUSkogsmarksgränd 17SE-90183 UmeåSweden College of Forestry Guangxi UniversityNanning 530004China Key Laboratory of Tree Breeding and Cultivation of National Forestry and Grassland Administration Research Institute of ForestryChinese Academy of ForestryBox 1958Beijing 100091China.

Background:A number of hypotheses and theories,such as the Janzen-Connell hypothesis,have been proposed to explain the natural maintenance of biodiversity in tropical and temperate forest ***,to date the details of the processes behind this natural maintenance are still *** two new nearest-neighbour characteristics were proposed and in this paper we demonstrate how they can contribute to a better understanding of the ontogenesis of global forest structure from localised ***:We applied the new species and size segregation functions together with appropriate test procedures to four example woodland data sets from China at Daqingshan,Jiaohe,Jiulongshan and Xiaolongshan forest *** addition we quantified the morphology of the new characteristics and modelled a neighbourhood allometric coefficient linking the two ***:The results revealed quite different species segregation patterns with both conspecific and heterospecific *** found these to be generally matched by equivalent size segregation patterns of attraction of similar and different *** was straightforward to model the size segregation function from the knowledge of the species segregation function by estimating a neighbourhood allometric ***:The new characteristics have helped to quantify the extent and rate of decline of neighbourhood interactions in terms of spatial species and size *** the allometric neighbourhood coefficient the analysis highlighted once more how closely related species and size segregation are,thus supporting the minglingsize *** both a traditional and a restricted random-labelling test has provided a valuable tool for understanding the exact nature of species-mingling and size-inequality relationships.

关键词： Species segregation function Size segregation function Mingling-size hypothesis Neighbourhood allometric coefficient random labelling