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Acute right insular ischaemic lesions and poststroke left ventricular dysfunction

Stroke & Vascular Neurology 2023年第4期8卷 301-306页

作者： Klemens Winder Carolina Villegas Millar Gabriela Siedler Michael Knott arnd dörfler Anna Engel Stephan Achenbach Max J Hilz Bernd Kallmünzer Stefan Schwab Frank Seifert Kilian Fröhlich Neurology University Hospital ErlangenFriedrich-Alexander-Universität(FAU)Erlangen-NürnbergErlangenGermany Neurology University Hospital and University of ZürichZürichSwitzerland Neuroradiology University Hospital ErlangenFriedrich-Alexander Universität(FAU)Erlangen-NürnbergErlangenGermany Cardiology University Hospital ErlangenFriedrich-Alexander-Universität(FAU)Erlangen-NürnbergErlangenGermany

Introduction Myocardial injury related to acute ischaemic stroke is common even without primary cardiac *** intended to determine associations between values of left ventricular ejection fraction(LVEF)and ischaemic stroke lesion *** Of a local database,patients with acute first-ever ischaemic stroke confirmed by brain imaging but without pre-existing heart disease were *** cardiac morphology and LVEF were obtained from transthoracic or transesophageal echocardiography,and impaired LVEF was categorised as mild(35%-50%),moderate(34%-25%)and severe(0.1 ng/mL),atrial fibrillation and cardiac wall motion abnormalities were assessed and compared between patients with and without impaired LVEF after stroke(significance:pd LVEF after stroke with sites of ischaemic *** Of 1209 patients who had a stroke,231(mean age 66.3±14.0 years)met the inclusion criteria;40 patients(17.3%)had an impaired LVEF after *** with impaired LVEF had higher infarct volumes(53.8 mL vs 30.0 mL,p=0.042),a higher prevalence of troponin increase(17.5%vs 4.2%,p=0.006),cardiac wall motion abnormalities(42.5%vs 5.2%,pd atrial fibrillation(60.0%vs 26.2%,p50%.The multivariate voxelwise lesion analysis yielded associations between decreased LVEF and damaged voxels in the insula,amygdala and operculum of the right *** Our imaging analysis unveils a prominent role of the right hemispheric central autonomic network,especially of the insular cortex,in the brain-heart *** results support preliminary evidence that acute ischaemic stroke in distinct brain regions of the central autonomic network may directly impair cardiac function and thus further supports the concept of a distinct stroke-heart syndrome.

关键词： impaired ischaemic ventricular

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Assessing the impact of the maritime silk road

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Journal of Ocean Engineering and Science 2017年第3期2卷 186-195页

作者： Orestis Schinas arnd Graf von Westarp HSBA Hamburg School of Business AdministrationGermanyAlter Wall 38Hamburg 20457Germany Hamburg Süd Willy-Brandt-Straße 59-6520457 HamburgGermay

The plans for the Maritime Silk Road affect the existing liner *** purpose of this paper is to quantify using the terms of network theory the impact of these plans and to project the effects on the fleet,utilization,port throughput,and carbon *** analysis is based on publicly available information and reasonable fleet deployment *** also considers current and alternative routing schedules from Shanghai to *** impact of existing and expected emission control areas(ECAs)along the port chains is also considered.

关键词： Maritime transportation One Belt One Road(OBOR) Liner shipping Environmental impact

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different Responses of Sexual and Asexual Reproduction of Arundinella hirta to Flooding

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Frontiers in Biology 2006年第1期1卷 46-49页

作者： Zeng Bo Fu Tianfei Ulrich Schurr arnd J.Kuhn School of Life Science Southwest China UniversityChongqing 400715China Key Laboratory of Eco-environments in Three Gorges Reservoir Region(MOE) Southwest China UniversityChongqing 400715China Chongqing Key Laboratory of Plant Ecology and Resources Research in Three Gorges Reservoir Region Southwest China UniversityChongqing 400715China Research Center of Juelich ICG Ⅲ(Phytosphere)52425 JuelichGermany

The sexual and asexual reproductive features of the graminoid species Arundinella hirta growing at riversides of the Jialing River were *** was found that the total seed mass,seed number per plant,and sexual reproductive allocation of *** decreased with decreasing bank elevation,and plants growing at the lowest elevations of banks subjected to intense flooding did not show sexual *** total plant biomass and the number of ramifications per plant increased with flooding intensity,which implies that,contrary to sexual reproduction,asexual reproduction of *** was enhanced by flooding.

关键词： Arundinella hirta asexual reproduction flooding reproductive allocation sexual reproduction

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decisive Parameters for Backwater Effects Caused by Floating debris Jams

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Open Journal of Fluid dynamics 2017年第4期7卷 475-484页

作者： arnd Hartlieb Laboratory of Hydraulic and Water Resources Engineering Technical University of Munich Obernach Germany

The dimensional analysis of the backwater effect caused by debris jams results in the Froude number of the approach flow in the initial situation prior to debris jam formation and the debris density as decisive parameters. For the more precise detection of the influence of both parameters the results of different hydraulic model test series at the Laboratory of Hydraulic and Water Resources Engineering of the Technical University of Munich concerning debris jams at spillways as well as at racks for the retention of wooden debris were uniformly evaluated. On the one hand a significant increase of the backwater effect with a rising Froude number of the approach flow could be shown. This is in good correlation to recent test results for debris jams at retention racks at the Laboratory of Hydraulics, Hydrology and Glaciology of the Swiss Federal Institute of Technology Zurich. On the other hand a significant increase of the backwater effect could also be shown for a rising debris density. However, the test results also show that significantly different backwater effects can occur in different test runs with identical test conditions. These differences are a result of the randomness of debris jam development, and therefore, a more exact quantification of the dependence of the backwater effect on the Froude number of the approach flow and on the debris density is not considered useful for the present results.

关键词： Hydraulic Engineering Natural Hazards Floating debris Jams Large-Scale Hydraulic Model Tests

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Offshore Wind-Parks and Northern Europe＇s Mild Winters： Contribution from Ships, Fishery, et cetera？

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Journal of Shipping and Ocean Engineering 2016年第1期6卷 46-56页

作者： arnd BERNAERTS Hamburg Germany

The marine environment of North Sea and Baltic is one of the most heavily strained by numerous human activities. Simultaneously water and air temperatures increase more than elsewhere in Europe and globally, which cannot be explained with ＂global warming＂. The climatic change issue would be better understood if this extraordinary regional warming is sufficiently explained. The regional features are unique for in-depth studies due to different summer-winter conditions, shallowness of the seas, geographical structure, and main pathway for maritime weather patterns moving eastwards. The impact of sea activities on the seasonal sea water profile structure is contributing to stronger regional warming, change in growing season, and less severe sea ice conditions. The impact of the man, whether small or large, should be understood very soon and very thoroughly.

关键词： Human maritime activities sea temperature increase North Sea and Baltic warming change in seasonality sea icedecrease.

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Early cisternal fibrinolysis is more effective than rescue spasmolysis for the prevention of delayed infarction after subarachnoid haemorrhage

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Stroke & Vascular Neurology 2022年第2期7卷 108-113页

作者： Roland Roelz Christian Scheiwe Jürgen Grauvogel Istvan Csok Volker arnd Coenen Jürgen Beck Peter C Reinacher department of Neurosurgery Medical Center-University of FreiburgFreiburgGermany department of Stereotactic and Functional Neurosurgery Medical Center-University of FreiburgFaculty of MedicineFreiburgGermany Fraunhofer Institute for Laser Technology(ILT) AachenGermany

Background To compare the efficacy of two different concepts of cisternal therapy—PREVENTIVE fibrinolysis plus on-demand spasmolysis versus RESCUE spasmolysis—for the prevention of cerebral vasospasm(CVS)and delayed cerebral infarction(dCI)in patients with aneurysmal subarachnoid haemorrhage(aSAH).Methods Retrospective analysis of 84 aSAH patients selected for cisternal therapy for dCI prevention.66 high-risk patients received PREVENTIVE cisternal therapy to enhance blood *** stereotactic catheter ventriculocisternostomy(STX-VCS)or intraoperative placement of a cisterno-ventriculostomy catheter(CVC),followed by fibrinolytic cisternal lavage using urokinase was *** case of vasospasm,nimodipine was applied intrathecally.22 low-risk patients who developed CVS against expectations were selected for STX-VCS as RESCUE intervention for cisternal spasmolysis with *** of dCI and mean flow velocities of daily transcranial doppler(TCd)ultrasonographies were *** despite a higher prespecified dCI risk,patients selected for PREVENTIVE intervention primarily aiming at blood clearance had a lower dCI rate compared with patients selected for intrathecal spasmolysis as a RESCUE therapy(11.3%vs 18.2%).After intrathecal treatment onset,CVS(TCd>160 cm/s)occurred in 45%of patients with PREVENTIVE and 77%of patients with RESCUE therapy(p=0.013).A stronger response of CVS to intrathecal nimodipine was observed in patients with PREVENTIVE intervention as the mean CVS duration after start of intrathecal nimodipine was 3.2 days compared with 5.8 days in patients with RESCUE therapy(p=0.026).Conclusions PREVENTIVE cisternal therapy directed at blood clearance is more effective for the prevention of CVS and delayed infarction compared with cisternal RESCUE spasmolysis.

关键词： prevention spasmolysis infarction

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Performance of dexcom G5 and FreeStyle Libre sensors tested simultaneously in people with type 1 or 2 diabetes and advanced chronic kidney disease

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World Journal of Clinical Cases 2022年第22期10卷 7794-7807页

作者： arndís FinnaÓlafsdóttir Mervi Andelin Aso Saeed Sheyda Sofizadeh Hussein Hamoodi Per-Anders Jansson Marcus Lind department of Medicine NU-Hospital GroupUddevallaSweden department of Molecular and Clinical Medicine Institute of MedicineSahlgrenska AcademyUniversity of GothenburgGöteborgSweden department of Nephrology Gothenburg UniversitySahlgrenska AcademyInstitute Internal MedicineGöteborgSweden Statistiska Konsultgruppen GöteborgSweden Wallenberg Laboratory Department of Molecular and Clinical MedicineInstitute of MedicineSahlgrenska AcademyUniversity of GothenburgGöteborgSweden

BACKGROUNd Advanced chronic kidney disease(CKd) is a common complication for people with type 1 and 2 diabetes and can often lead to glucose instability. Continuous glucose monitoring(CGM) helps users monitor and stabilize their glucose levels. To date, CGM and intermittent scanning CGM are only approved for people with diabetes but not for those with advanced *** To compare the performance of dexcom G5 and FreeStyle Libre sensors in adults with type 1 or 2 diabetes and advanced *** This was a non-randomized clinical trial that took place in two outpatient clinics in western Sweden. All patients with type 1 or 2 diabetes and an estimated glomerular filtration rate(eGFR) of d to participate. Forty patients(full analysis set = 33) carried the dexcom G5 sensor for 7 d and FreeStyle Libre sensor for 14 d simultaneously. For referencing capillary blood glucose(SMBG) was measured with a high accuracy glucose meter(HemoCue®) during the study period. At the end of the study, all patients were asked to answer a questionnaire on their experience using the *** The mean age was 64.1(range 41-77) years, hemoglobin A1 c was 7.0% [standard deviation(Sd) 3.2], and diabetes duration was 28.5(Sd 14.7) years. A total of 27.5% of the study population was on hemodialysis and 22.5% on peritoneal dialysis. The mean absolute relative difference for dexcom G5 vs SMBG was significantly lower than that for FreeStyle Libre vs SMBG [15.2%(Sd 12.2) vs 20.9%(Sd 8.6)], with a mean difference of 5.72 [95% confidence interval(CI): 2.11-9.32;P = 0.0036]. The mean absolute difference was also significantly lower for dexcom G5 than for FreeStyle Libre, 1.21 mmol/L(Sd 0.78) and 1.76 mmol/L(Sd 0.78), with a mean diffrenec of 0.55(95%CI: 0.27-0.83;P = 0.0004).The mean difference(Md) was-0.107 mmol/L and-1.10 mmol/L(P = 0.0002), respectively. In all, 66% of FreeStyle Libre values were in the no risk zone on the surveillance error grid compared t

关键词： Type 1 diabetes Type 2 diabetes Chronic kidney disease Continuous glucose monitoring Accuracy Mean absolute relative difference

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滑动多层技术的二维快速小角度激发成像序列在直肠癌腹部转移诊断中的应用价值

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中华放射学杂志 2008年第12期42卷 1287-1291页

作者：熊斌 Tobias Baumann 冯敢生 arnd-Oliver Schaefer Mathias Langer 华中科技大学同济医学院附属协和医院放射科武汉430022 department of diagnostic Radiology University Hospital of Freiburg 79106 Germany

目的探讨采用滑动多层（SMS）技术的二维快速小角度激发成像（FLASH-2d）序列在直肠癌腹部转移灶诊断中的价值。方法由2名放射科医师回顾性分析15例经手术病理证实的直肠癌患者资料，15例均接受SMSFLASH-2dMRI和多层螺旋CT（MSCT）检查... 详细信息

目的探讨采用滑动多层（SMS）技术的二维快速小角度激发成像（FLASH-2d）序列在直肠癌腹部转移灶诊断中的价值。方法由2名放射科医师回顾性分析15例经手术病理证实的直肠癌患者资料，15例均接受SMSFLASH-2dMRI和多层螺旋CT（MSCT）检查（4例进行了2次检查）。以SMS和MSCT及6个月内所有随诊检查的最终一致意见作为疾病诊断的参考标准。采用Kappa。检验评价2种检查方法对于直肠癌肝转移、淋巴结转移和骨转移诊断的一致性和不同观察者对疾病诊断的一致性，并比较2种方法对各种转移病灶诊断的灵敏度。结果2名医师采用SMS技术都发现了60个病灶中的56个转移灶，灵敏度均为93．33％（56／60）；采用MSCT均发现了50个病灶，灵敏度均为83．33％（50／60）。对于肝转移灶的诊断，2名医师采用SMS诊断的灵敏度分别为97．44％（38／39）和100％（39／39）；采用MSCT诊断的灵敏度均为100％（39／39）。对于淋巴结转移的诊断，SMS诊断的灵敏度为85．71％（12／14）和71．43％（10／14）；MSCT分别为78．57％（11／14）和71．43％（10／14）。对骨转移灶的诊断，SMS的灵敏度分别为85．71％（6／7）和100％（7／7）；MSCT分别为0（0／7）和14．29％（1／7）。结论SMSFLASH-2d序列在对直肠癌肝转移和淋巴结转移诊断上有和MSCT相同的能力，对于骨转移灶的诊断则明显较MSCT敏感。

关键词：结直肠肿瘤磁共振成像图像处理计算机辅助

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小鼠单纯疱疹病毒性角膜炎中基质金属蛋白酶的表达及活性研究

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中华眼科杂志 2004年第6期40卷 395-399页

作者：杨燕宁 dirk Bauer 李海平 arnd Heiligenhaus 武汉大学人民医院眼科 430060 德国埃森大学临床医院眼科

目的　探讨角膜感染Ⅰ型单纯疱疹病毒 (HSV 1)后基质金属蛋白酶 (MMPs)及其组织抑制剂 (TIMPs)在角膜中的分布及酶活性表达。方法　BALB/c小鼠眼角膜接种HSV 1(KOS株 )以诱发单纯疱疹病毒性角膜炎 (HSK)。分别收集正常眼球及感染后第 2... 详细信息

目的　探讨角膜感染Ⅰ型单纯疱疹病毒 (HSV 1)后基质金属蛋白酶 (MMPs)及其组织抑制剂 (TIMPs)在角膜中的分布及酶活性表达。方法　BALB/c小鼠眼角膜接种HSV 1(KOS株 )以诱发单纯疱疹病毒性角膜炎 (HSK)。分别收集正常眼球及感染后第 2、7、14及 2 8天的感染眼球。应用免疫组织化学法和Westernblot方法检测MMP 2、 8、 9及TIMP 1、 2在角膜组织中的表达 ,并应用酶谱(Zymography)技术检测MMPs的酶活性。结果　感染后第 2天 ,感染眼的MMP 2、 9及TIMP 1、 2表达比未感染眼增加且表达主要位于浅表基质层及上皮下的炎性细胞中。感染后第 14和 2 8天可见坏死性角膜炎及角膜溃疡形成 ,同时角膜基质和浸润的炎性细胞中尤其溃疡处 ,可见MMP 2、 9及TIMP 1、 2表达显著增加。溃疡区域有大量MMP 8阳性染色的中性粒细胞。角膜感染HSV 1后 ,明胶酶 (MMP 2、 9)活性和胶原酶 (MMP 8)活性均增强。结论　HSV 1角膜感染后 ,由角膜细胞和浸润的炎性细胞分泌产生的MMPs可能对上皮性角膜炎与溃疡形成过程起重要的促进作用。MMPs与TIMPs的相互作用可能对HSK的坏死性病变起重要调节作用。

关键词：小鼠单纯疱疹病毒性角膜炎基质金属蛋白酶基质金属蛋白酶组织抑制剂免疫组织化学

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纽马格推动客户BCF生产

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合成纤维 2005年第12期34卷 49-50页

作者： arnd Luppold Martin Rademacher Tilman Reutter

地毯和地毯纱市场总是充满着挑战,新的需求不断地出现.地毯业的时尚潮流在快速地变化着,同时全球性的压力也在稳步增长.地毯业在这样的竞争环境中必须找到能够保持成功的途径.在这种情况下,工艺链前期的BCF技术对地毯纱和地毯生产是否... 详细信息

地毯和地毯纱市场总是充满着挑战,新的需求不断地出现.地毯业的时尚潮流在快速地变化着,同时全球性的压力也在稳步增长.地毯业在这样的竞争环境中必须找到能够保持成功的途径.在这种情况下,工艺链前期的BCF技术对地毯纱和地毯生产是否成功起着决定性的作用.

关键词： BCF 生产客户地毯纱竞争环境全球性决定性工艺链需求

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