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Strain Influence on the Precipitation Kinetic Nb-V Microalloyed HSLA Steel

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Journal of Iron and Steel Research(International) 2011年第S1期18卷 278-281页

作者： Cartaya Elio armando Cabrera José María Prado José Manuel Departamento de Ciencia de Materiales e Ingeniería Metalúrgica ETSEIBUniversidad Politécnica de Catalu a Av.Diagonal 64708028 BarcelonaSpain Departamento de Manufactura y Materiales Facultad de Ingeniería MecánicaUniversidad de Oriente90400 Santiago de CubaCuba Fundación CTM Centro Tecnológico Av.Bases de Manresa 108242 ManresaSpain

The strain induced effect on the precipitation kinetics of a high strength low alloy (HSLA) steel microalloyed with Nb-V was *** stress relaxation method was employed to determine the dependence of the precipitation-time-temperature curves (PTT) on previous *** tests were performed over a temperature range of 850 to 1150 oC at a constant strain rate of 0.1 s-1 at three deformation levels,namely 5,15 and 25 *** emission scanning electron microscopy (FESEM) was used to study the progress of precipitation on samples obtained by interrupted relaxation test at different *** display the acceleration kinetics at increasing *** models are discussed and compared with the present experimental results.

关键词： strain induced precipitation kinetic HSLA stress relaxation PTT

Molecular isolation and identification of Mycobacterium avium *** in Didelphis virginiana from Hidalgo,Mexico

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Asian Pacific Journal of Tropical Medicine 2020年第3期13卷 131-136页

作者： Nallely Rivero-Perez Juan Ocampo-López Benjamín Valladares-Carranza Fabián R.Gómez de Anda Francisco J.Pena Jiménez Victor M.Martínez Juárez armando Peláez Acero Jose I.Olave Leyva Deyanira Ojeda-Ramírez Adrian Zaragoza-bastida Area Académica de Medicina Veterinaria y Zootecnia Instituto de Ciencias AgropecuariaUniversidad Autónoma del Estado de HidalgoAv.Universidad Km 1Ex-Hda.de AquetzalpaC.P.43600 TulancingoHidalgoMéxico Centro de Investigación y Estudios Avanzados en Salud Animal Facultad de Medicina Veterinaria y ZootecniaUniversidad Autónoma del Estado de MéxicoKm 15.5 Carretera Panamericana Toluca-AtlacomulcoC.P.50200 TolucaEstado de MéxicoMéxico Centro Universitario del Sur/División de Ciencias de la Salud/Departamento de Ciencias Clínicas/Hospital Veterinario CUSUR Universidad de Guadalajara Av.Enrique Arreola Silva No.883colonia centro C.P.49000Ciudad GuzmánJaliscoMéxico

Objective:To isolate and identify the exact species of the genus Mycobacterium from Didelphis(D.)virginiana,and the direct implications of this bacterium to public health and veterinary ***:Thirty-one *** were captured and necropsied in Hidalgo,*** samples were collected to culture mycobacteria present and examine individual specimens’*** identification was obtained through the application of amplification and sequencing of 16S rDNA ***:Three strains were isolated and identified as Mycobacterium(M.)avium *** by utilizing *** complexspecific *** lesions were observed in the subpleural zone(granuloma gradeⅡ)and bronchial(granuloma gradeⅠ)of the lungs of *** with positive ***:Three strains of *** ***,from lung tissue samples of *** were *** subspecies of *** has important implications in public health and veterinary medicine.

关键词： Didelphis virginiana Mycobacterium avium complex Mycobacterium avium subsp.hominissuis Public health

A genetic linkage map of the threatened catfish Lophiosilurus alexandri:Inferences on effective population size

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Aquaculture and Fisheries 2023年第6期8卷 689-694页

作者： M.Raquel M.Coimbra Renata da S.Farias Bruno C.N.Rda Silva Andres Blanco Miguel Hermida armando Caballero Michael Bekaert Paulino Martinez Department of Fisheries and Aquaculture Federal Rural University of PernambucoRua Dom Manuel de MedeirosS/nDois IrmaosRecifePE52171-900Brazil Department of Zoology Genetics and Physical AnthropologyACUIGEN GroupFaculty of VeterinaryUniversity of Santiago de Compostel1Campus of LugoLugo27002Spain Center of Marine Research University of VigoFaculty of BiologyVigo36310Spain Institute of Aquaculture University of StirlingScotlandFK94LAUnited Kingdom

We report the first genetic linkage map of the catfish Lophiosilurus alexandri,a South American threatened and promising aquaculture catfish *** the progeny of three full-sib families,with 141,74,and 49 offspring,respectively,we could genotype 2351 SNP markers using the ddRAD technology,shared by the male and the female maps *** averaged,female and male maps spanned a total length of 2201.3 cM,2481.9 cM,and 1872.8 cM,respectively,and comprehended the expected 27 linkage groups according to the karyotype information of the species(2n=54).The recombination rate was nearly twice higher in the female than in the male *** average map was used to estimate the historical effective population size(Ne)of the species from linkage disequilibrium between pairs of SNPs using parental individuals and revealed a remarkable drop in Ne about 20-25 generations in the *** construction of the biggest artificial reservoir in Latin America and associated nutrient retention is pointed as a possible reason for such a reduction and suggests a reevaluation of the conservation status of the *** current map lays the groundwork for understanding the genetic basis of economically important traits in breeding programs and will be useful for the genome assembly of this important commercial species.

关键词： breeding linkage size

Multiphoton synthetic lattices in multiport waveguide arrays: synthetic atoms and Fock graphs

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Photonics Research 2020年第7期8卷 1161-1170页

作者： Konrad Tschernig Roberto de J.León-Montiel armando Pérez-Leija Kurt Busch Max-Born-Institut 12489 BerlinGermany Instituto de Ciencias Nucleares Universidad Nacional Autónoma de MéxicoApartado Postal 70-54304510 Cd.Mexico CityMexico Humboldt-Universität zu Berlin Institut für PhysikAG Theoretische Optik&Photonik12489 BerlinGermany

Activating transitions between internal states of physical systems has emerged as an appealing approach to create lattices and complex *** such a scheme,the internal states or modes of a physical system are regarded as lattice sites or network nodes in an abstract space whose dimensionality may exceed the systems’apparent(geometric)*** introduces the notion of synthetic dimensions,thus providing entirely novel pathways for fundamental research and ***,we analytically show that the propagation of multiphoton states through multiport waveguide arrays gives rise to synthetic dimensions where a single waveguide system generates a multitude of synthetic *** these synthetic lattices exist in photon-number space,we introduce the concept of pseudo-energy and demonstrate its utility for studying multiphoton interference ***,the spectrum of the associated pseudo-energy operator generates a unique ordering of the relevant *** with generalized pseudo-energy ladder operators,this allows for representing the dynamics of multiphoton states by way of pseudo-energy term diagrams that are associated with a synthetic *** a result,the pseudo-energy representation leads to concise analytical expressions for the eigensystem of N photons propagating through M nearest-neighbor coupled *** the regime where N≥2 and M≥3,nonlocal coupling in Fock space gives rise to hitherto unknown all-optical dark states that display intriguing nontrivial dynamics.

关键词： synthetic dimensions system

Receptor for advanced glycation end-products axis and coronavirus disease 2019 in inflammatory bowel diseases:A dangerous liaison?

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World Journal of Gastroenterology 2021年第19期27卷 2270-2280页

作者： armando Rojas Ivan Schneider Cristian Lindner Ileana Gonzalez Miguel Angel Morales Medicine Faculty Catholic University of MauleTalca 3634000Chile Department of Molecular and Clinical Pharmacology Program Institute of Biomedical SciencesUniversity of ChileSantiago 8320000Chile

Compelling evidence supports the crucial role of the receptor for advanced glycation end-products(RAGE)axis activation in many clinical *** the beginning of the coronavirus disease 2019 pandemic,there is an increasing concern about the risk and handling of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection in inflammatory gastrointestinal disorders,such as inflammatory bowel diseases(IBD).However,clinical data raised during pandemic suggests that IBD patients do not have an increased risk of contracting SARS-CoV-2 infection or develop a more severe course of *** the present review,we intend to highlight how two potentially important contributors to the inflammatory response to SARS-CoV-2 infection in IBD patients,the RAGE axis activation as well as the cross-talk with the renin-angiotensin system,are dampened by the high expression of soluble forms of both RAGE and the angiotensin-converting enzyme(ACE)*** soluble form of RAGE functions as a decoy for its ligands,and soluble ACE2 seems to be an additionally attenuating contributor to RAGE axis activation,particularly by avoiding the transactivation of the RAGE axis that can be produced by the virus-mediated imbalance of the ACE/angiotensin II/angiotensin II receptor type 1 pathway.

关键词： COVID-19 Inflammatory bowel diseases Advanced glycation Angiotensinconverting enzyme 2 Alarmins Receptor for advanced glycation end-products Receptor for advanced glycation end-products axis Inflammation

Optimized management of advanced hepatocellular carcinoma:Four long-lasting responses to sorafenib

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World Journal of Gastroenterology 2011年第19期17卷 2450-2453页

作者： Giovanni Abbadessa Lorenza Rimassa Tiziana Pressiani Cynthia Carrillo-Infante Emanuele Cucchi armando Santoro Department of Medical Oncology and Hematology Istituto Clinico Humanitas Department of Human Pathology and Oncology Program of Genetic OncologyUniversity of Siena Department of Human Pathology and Oncology Program of Molecular PathologyUniversity of Siena Department of Radiology and Ultrasound Polidiagnostico CAM

The therapeutic options for hepatocellular carcinoma (HCC) have been so far rather *** has shown an overall survival benefit and has become the new standard of care for advanced ***,in clinical practice,some patients are discontinuing this drug because of side effects,and misinterpretation of radiographic response may contribute to *** highlight the importance of prolonged sorafenib ad-ministration,even at reduced dose,and of qualitative and careful radiographic *** observed two partial and two complete responses,one histologically confirmed,with progression-free survival ranging from 12 to 62 *** of the responses were achieved following substantial dose reductions,and a gradual change in lesion density preceded or paralleled tumor shrinkage,as seen by computed *** report supports the feasibility of dose adjustments to allow prolonged administration of sorafenib,and highlights the need for new imaging criteria for a more appropriate characterization of response in HCC.

关键词：化管理肝癌晚期计算机断层扫描治疗方案肝细胞癌临床实践影像学

Identification in Lupin Seed of a Serine- Endopeptidase Activity Cleaving between Twin Arginine Pairs and Causing Limited Proteolysis of Seed Storage Proteins

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Molecular Plant 2012年第5期5卷 1011-1019页

作者： Chiara Magni Fabio Sessa Gabriella Tedeschi armando Negri Alessio Scarafoni Alessandro Consonni Marcello Duranti Department of AgriFood Molecular Sciences Universita degli Studi di Milano Via Celoria 2 20133 Milano Italy Department of Animal Pathology Hygiene and Veterinary Public Health--Section of Biochemistry Universita degli Studi di Milano Italy

The occurrence of twin-arginine motifs （-R-R-） in the amino acid sequences of animal pro-proteins frequently defines the cleavage site（s） for their structural/functional maturation. No information is available on the presence and possible biological meaning of these motifs in the seed storage proteins. In this work, a novel endopeptidase activity with cleavage specificity to twin-arginine pairs has been detected in mature dry Lupinus albus seeds. The endopeptidase was tested with a number of endogenous and exogenous protein substrates, which were selected according to the pres- ence of one or more twin-arginine residue motifs in their amino acid sequences. The observed hydrolysis patterns were limited and highly specific. Partial proteolysis led to stable polypeptide fragments that were characterized by 1- and 2-D electrophoresis. Selected polypeptides were submitted to N-terminal amino acid sequencing and mass spectrometry anal- yses, These approaches, supported by bioinformatic analysis of the available sequences, allowed the conclusion that the polypeptide cleavage events had occurred at the peptide bonds comprised between twin-arginine residue pairs with all tested protein substrates. The endopeptidase activity was inhibited by 4-（2-AminoEthyl）Benzene-Sulphonyl Fluoride hy- drochloride （AEBSF）, leupeptin, and serine proteinase protein inhibitors, while it was not affected by pepstatin, trans- EpoxysuccinyI-L-leucylamido（4-guanidino）butane （E64）, and ethylenediaminetetraacetic acid （EDTA）, thus qualifying the Arg-Arg cleaving enzyme as a serine endopeptidase. The structural features of storage proteins from lupin and other legume seeds strongly support the hypothesis that the occurrence of an endopeptidase activity cleaving -R-R- bonds may be functional to facilitate their degradation at germination and possibly generate polypeptide fragments with specific biological activity.

关键词： Lupinus albus leguminous seeds twin-arginine residues proteolysis storage proteins proteolytic conver-sion N-terminal amino acid sequence analysis.

Crop phenotyping in a context of global change:What to measure and how to do it

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Journal of Integrative Plant Biology 2022年第2期64卷 592-618页

作者： Jose Luis Araus Shawn Carlisle Kefauver Omar Vergara-Díaz Adrian Gracia-Romero Fatima Zahra Rezzouk Joel Segarra Maria Luisa Buchaillot Melissa Chang-Espino Thomas Vatter Rut Sanchez-Bragado Joséarmando Fernandez-Gallego Maria Dolores Serret Jordi Bort Integrative Crop Ecophysiology Group Plant Physiology SectionFaculty of BiologyUniversity of BarcelonaBarcelonaSpain AGROTECNIO Center LleidaSpain Plant Ecophysiology and Metabolism Lab ITQB NovaPlant Sciences DivisionOeirasPortugal Programa de Ingeniería Electrónica Facultad de IngenieríaUniversidad de IbaguéIbaguéColombia

High-throughput crop phenotyping,particularly under field conditions,is nowadays perceived as a key factor limiting crop genetic *** not only facilitates conventional breeding,but it is necessary to fully exploit the capabilities of molecular breeding,and it can be exploited to predict breeding targets for the years ahead at the regional level through more advanced simulation models and decision support *** terms of phenotyping,it is necessary to determined which selection traits are relevant in each situation,and which phenotyping tools/methods are available to assess such *** sensing methodologies are currently the most popular approaches,even when lab-based analyses are still relevant in many *** top of that,data processing and automation,together with machine learning/deep learning are contributing to the wide range of applications for *** review addresses spectral and red-green-blue sensing as the most popular remote sensing approaches,alongside stable isotope composition as an example of a lab-based tool,and root phenotyping,which represents one of the frontiers for field ***,we consider the two most promising forms of aerial platforms(unmanned aerial vehicle and satellites)and some of the emerging data-processing *** review includes three Boxes that examine specific case studies.

关键词： crop phenotyping deep learning models photosynthesis platforms remote sensing roots satellites sensors stable isotopes

Advanced-glycation end-products axis:A contributor to the risk of severe illness from COVID-19 in diabetes patients

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World Journal of Diabetes 2021年第5期12卷 590-602页

作者： armando Rojas Cristian Lindner Ileana Gonzàlez Miguel Angel Morales Biomedical Research Labs Medicine FacultyCatholic University of MauleTalca 3460000Chile Medicine Faculty Catholic University of MauleTalca 3460000Chile Molecular and Clinical Pharmacology Program Institute of Biomedical SciencesUniversity of ChileSantiago 8320000Chile

Compelling pieces of evidence derived from both clinical and experimental research has demonstrated the crucial role of the receptor for advanced-glycation end-products(RAGE)in orchestrating a plethora of proinflammatory cellular responses leading to many of the complications and end-organ damages reported in patients with diabetes mellitus(DM).During the coronavirus disease 2019(COVID-19)pandemic,many clinical reports have pointed out that DM increases the risk of COVID-19 complications,hospitalization requirements,as well as the overall severe acute respiratory syndrome coronavirus 2 case-fatality *** the present review,we intend to focus on how the basal activation state of the RAGE axis in common preexisting conditions in DM patients such as endothelial dysfunction and hyperglycemia-related prothrombotic phenotype,as well as the contribution of RAGE signaling in lung inflammation,may then lead to the increased mortality risk of COVID-19 in these ***,the crosstalk between the RAGE axis with either another severe acute respiratory syndrome coronavirus 2 receptor molecule different of angiotensin-converting enzyme 2 or the renin-angiotensin system imbalance produced by viral infection,as well as the role of this multi-ligand receptor on the obesity-associated lowgrade inflammation in the higher risk for severe illness reported in diabetes patients with COVID-19,are also discussed.

关键词： COVID-19 Diabetes mellitus Advanced glycation Alarmins Advancedglycation end-products axis Inflammation