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Method to measure tree-ring width,density,elemental composition,and stable carbon and oxygen isotopes using one sample

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Journal of Forestry Research 2024年第3期35卷 167-174页

作者： Chenxi Xu Yaru Zhao Wenling An Qingyu Zhao Yucheng Liu masaki Sano Takeshi Nakatsuka Key Laboratory of Cenozoic Geology and Environment Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029People's Republic of China CAS Center for Excellence in Life and Paleoenvironment Beijing 100044People's Republic of China College of Earth Sciences University of Chinese Academy of SciencesBeijing 100049People's Republic of China Graduate School of Environment Studies Nagoya UniversityNagoya 4648601Japan

Tree-ring width(RW),density,elemental com-position,and stable carbon and oxygen isotope(δ^(13)C,δ^(18)O)are widely used as proxies to assess climate change,ecology,and environmental pollution;however,a specific pretreat-ment has been needed for each ***,we developed a method by which each proxy can be measured in the same ***,the sample is polished for ring width *** obtaining the ring width data,the sample is cut to form a 1-mm-thick wood *** sample is then mounted in a vertical sample holder,and gradually scanned by an X-ray ***,the count rates of the fluorescent photons of elements(for chemical characteriza-tion)and a radiographic grayscale image(for wood density)are obtained,*** density and the element content are ***,cellulose is isolated from the 1-mm wood plate by removal of lignin,and *** producing this cellulose plate,cellulose subsamples are separated by knife under the microscope for inter-annual and intra-annual stable carbon and oxygen isotope(δ^(13)C,δ^(18)O)*** on this method,RW,density,elemental composition,δ^(13)C,and δ^(18)O can be measured from the same sample,which reduces sample amount and treatment time,and is helpful for multi-proxy comparison and combination research.

关键词： Tree-ring width Tree-ring density Tree-ring elemental composition Tree-ring stable carbon and oxygenisotopes

Hyperbaric Oxygen Stimulates the Proliferation and Differentiation of Raw264.7 Cells

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Open Journal of Stomatology 2015年第12期5卷 309-320页

作者： Tomotaka Sugi Masanori Sasaki Takahiro Yamashiro Takaoki Tsuneyoshi arioka masaki Akihiko Matsumoto Kumamaru Wataru Nakano Hiroyuki Mori Yoshihide Section of Oral and Maxillofacial Surgery Division of Maxillofacial Diagnostic and Surgical Sciences Faculty of Dental Science Kyushu University Japan

Background: Hyperbaric Oxygen (HBO) Therapy improves the outcome of various types of sugery, such as postoperative bone grafts, fixation of jaw fractures, and osteoplasty of jaw deformities. Therefore, it is important to determine the effects of HBO on bone regeneration. The purpose of this study was to clarify the influence of a hyperbaric oxygen environment on bone regeneration at the osteoclastogenic cytokines level. Sample & Methods: RAW264.7 cells were stimulated under the various conditions by using a hyperbaric oxygen chamber. We evaluated the ability of the RAW264.7 macrophages to proliferate, differentiate and produce various osteoclastogenic cyto-kines. Results: A hyperbaric oxygen (HBO) environment and high concentration oxygen (HCO) environment increase cellular proliferation in a time-dependent manner. On the other hand, a HCO environment and a hyperbaric with room air (HBA) environment enhanced the differentiation of RAW264.7 cells. In addition, NFATc1 and c-Fos were increased by both the HBA environment and HCO environment. However, the effects of HBA and HCO environments were in contrast with each other with regard to RANK, TNF-α, C-FMS and TRAP. Conclusions: It was suggested that a HBO environment influenced the bone regeneration by altering osteoclastogenic cytokines level, and that a HCO environment and HBA environment acted independently on the proliferation and differentiation of macrophages and the secretion of osteoclastogenic cytokines, and that they acted in concert in a hyperbaric oxygen environment to induce conditions favoring regeneration.

关键词： Hyperbaric Oxygen Therapy Bone Regeneration Osteoclast RAW264.7

日本和美国的基础设施管理经验及教训研究(英文)

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四川理工学院学报（自然科学版） 2009年第5期22卷 1-3页

作者： Kunio Mori masaki arioka Kenji Sakata 森咨询有限公司日本立命馆大学日本土木学会

经过20世纪后期大量的建设后,面临着诸如桥梁破坏等新问题。同时,由于全球气候变暖现象,21世纪的基础设施管理制度必须建立在符合总成本效益比最小和防止全球变暖的条件下。文章介绍了日本和美国对社会基础设施的一些管理制度和经验。

关键词：基础设施管理全球变暖维修

Fluorescence‑Based Calibration Model for In‑Situ Measurement of Micro‑scaled Lubricant Thickness Distribution at Indentation Interface

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Nanomanufacturing and Metrology 2024年第2期7卷 76-88页

作者： Motoya Yoshikawa Saeko Fujii Shotaro Kadoya Tatsuya Sugihara masaki Michihata Satoru Takahashi Department of Precision Engineering The University of TokyoHongo 7‑3‑1BunkyoTokyo 113‑8656Japan Department of Mechanical Engineering Osaka UniversityYamadaoka 2‑1SuitaOsaka 565‑0871Japan

This study proposes a model for the measurement of microscale liquid film thickness distribution using fluorescence *** interfacial conditions between the tool and the workpiece in mechanical machining are important for understanding these phenomena and *** this study,indentation tests with transparent tools were used to observe interfaces;however,it was challenging to obtain the signal from a thin fluorescent liquid film on smooth and steeply inclined ***,fluorescence-based measurement,such as laser-induced fluorescence,was *** measure the absolute thickness of the thin fluorescent film,calibration of the measurement system is ***,a theoretical model was proposed considering the multiple reflections of excitation light and fluorescence at the inclined surface between the indenter and *** measuring the profile of the surface topography of the indented workpiece and comparing the results with those measured by a surface profiler,the validity of the proposed calibration method and the performance of this measurement system were *** measured surface profiles,including scratches of 2–4μm,were in good agreement,demonstrating the validity of the proposed method.

关键词： Laser-induced fluorescence(LIF) Thickness distribution In-situ measurement Lubricant Mechanical machining

牙周膜Wnt响应细胞对咀嚼力适应性反应的分子机制研究

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牙周膜Wnt响应细胞对咀嚼力适应性反应的分子机制研究

Evaluation of bacterial contamination and medium-term oncological outcomes of intracorporeal anastomosis for colon cancer:A propensity score matching analysis

第十四次中国口腔颌面外科学术会议

作者：张晓辉原雪徐全臣 masaki arioka 史咏鑫 John Brunski Jill Helms 四川大学华西口腔医院口腔颌面外科斯坦福大学医学院青岛大学口腔医学院九州大学牙学院

研究目的:在人类进化过程中,颌骨体积不断变小,一般认为是农业发展之后人类饮食变软引起的这种改变。牙周膜在缓冲和分散咀嚼力的过程中起到了关键作用,然而,当食物发生由硬到软的改变后,牙周膜对咀嚼力改变所产生的适应性反应的分子机... 详细信息

研究目的:在人类进化过程中,颌骨体积不断变小,一般认为是农业发展之后人类饮食变软引起的这种改变。牙周膜在缓冲和分散咀嚼力的过程中起到了关键作用,然而,当食物发生由硬到软的改变后,牙周膜对咀嚼力改变所产生的适应性反应的分子机制目前仍不明了。本研究旨在研究当咀嚼力发生改变后牙周膜内的Wnt响应细胞发生适应性反应的分子机制。研究方法:本实验分别利用Axin2LacZ、Axin2Cre/ERT2ROSAmT/mG转基因小鼠及野生型小鼠,在出生后15天随机分为硬食及软食两组,在不同时间点处死动物并取材,通过组织学、影像学、免疫组织化学染色、免疫荧光染色等手段对小鼠上颌第一磨牙牙周膜进行处理及分析。研究结果:硬食组小鼠代表了正常发育过程中牙周膜的变化,出生后第九天(P9)牙周膜内PCNA免疫组化染色结果显示有少量PCNA阳性细胞,X-gal染色显示牙周膜内可见一些Wnt响应细胞;P18牙周膜内出现大量PCNA阳性细胞和大量Wnt响应细胞;出生后3个月小鼠牙周膜内可见一些Wnt响应细胞,几乎没有PCNA阳性细胞。出生后15天,对Axin2Cre/ERT2ROSAmT/mG转基因小鼠给予腹腔注射他莫昔芬,将Wnt响应细胞的细胞膜标记为GFP阳性,P21可见硬食组牙周膜内有大量PCNA阳性及GFP阳性细胞,而软食组牙周膜内只见到少量PCNA阳性及GFP细胞。P60时硬食组GFP阳性细胞遍及几乎整个牙周膜间隙,而软食组Wnt响应细胞数量依然很少。研究结论:实验结果表明,正常咀嚼力是维持牙周膜内干细胞增殖和Wnt响应细胞数量的必要因素,当咬合力下降之后牙周膜内细胞增值活性下降,Wnt响应细胞减少,牙周膜韧带变细并排列稀疏,细胞密度下降,从而进一步影响牙槽骨密度。

关键词： Wnt响应细胞信号通路家系追踪牙周膜生物力学

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World Journal of Gastrointestinal Surgery 2024年第3期16卷 670-680页

作者： Hajime Kayano Nana Mamuro Yutaro Kamei Takashi Ogimi Hiroshi Miyakita Toshio Nakagohri Kazuo Koyanagi masaki Mori Seiichiro Yamamoto Department of Gastroenterological Surgery Tokai University School of MedicineIsehara 259-1193KanagawaJapan

BACKGROUND Although intracorporeal anastomosis(IA)for colon cancer requires longer operative time than extracorporeal anastomosis(EA),its short-term postoperative results,such as early recovery of bowel movement,have been reported to be equal or *** IA requires opening the intestinal tract in the abdominal cavity under pneumoperitoneum,there are concerns about intraperitoneal bacterial infection and recurrence of peritoneal dissemination due to the spread of bacteria and tumor ***,intraperitoneal bacterial contamination and medium-term oncological outcomes have not been *** cavity in *** Of 127 patients who underwent laparoscopic colon resection for colon cancer from April 2015 to December 2020,75 underwent EA(EA group),and 52 underwent IA(IA group).After propensity score matching,the primary endpoint was 3-year disease-free survival rates,and secondary endpoints were 3-year overall survival rates,type of recurrence,surgical site infection(SSI)incidence,number of days on antibiotics,and postoperative biological *** Three-year disease-free survival rates did not significantly differ between the IA and EA groups(87.2%and 82.7%,respectively,P=0.4473).The 3-year overall survival rates also did not significantly differ between the IA and EA groups(94.7%and 94.7%,respectively;P=0.9891).There was no difference in the type of recurrence between the two *** addition,there were no significant differences in SSI incidence or the number of days on antibiotics;however,postoperative biological responses,such as the white blood cell count(10200 vs 8650/mm^(3),P=0.0068),C-reactive protein(6.8 vs 4.5 mg/dL,P=0.0011),and body temperature(37.7 vs 37.5℃,P=0.0079),were significantly higher in the IA *** IA is an anastomotic technique that should be widely performed because its risk of intraperitoneal bacterial contamination and medium-term oncological outcomes are comparable to those of EA.

关键词： Colon cancer Intracorporeal anastomosis 3-year disease-free survival Recurrence Surgical site infection Postoperative biological response

Combined laparoscopic and thoracoscopic repair of adult right-sided Bochdalek hernia with massive liver prolapse: A case report

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World Journal of Clinical Cases 2024年第14期12卷 2420-2425页

作者： Shinya Mikami Sae Kimura Yoshitsugu Tsukamoto masaki Hiwatari Yasuhito Hisatsune Asako Fukuoka Tsunehisa Matsushita Takeharu Enomoto Takehito Otsubo Department of Gastrointestinal and General Surgery St.Marianna University School of MedicineKanagawa 216-8511Japan

BACKGROUND A Bochdalek hernia(BH)is a congenital diaphragmatic hernia that often develops in the neonatal *** typically occurs on the left side of the diaphragm.A right-sided BH in an adult is *** SUMMARY A 45-year-old man was referred to our hospital because of an abnormal shadow seen on chest radiography during a medical check-up.A chest radiograph showed elevation of the right *** tomography showed prolapse of multiple intraabdominal organs into the right thoracic cavity,corresponding to a right-sided *** herniated contents included the stomach,transverse colon,and left lobe of the *** left lobe of the liver was enlarged,particularly the medial *** surgery was ***,the left lobe of the liver was completely trapped in the thoracic ***,thoracoscopic manipulation had to be performed to return the liver to the abdominal *** hernia was repaired with interrupted nonabsorbable sutures and reinforced with *** Combined laparoscopic and thoracoscopic surgery was successfully performed for right-sided BH with massive liver prolapse and abnormal liver morphology.

关键词： Bochdalek hernia Right-sided Adult Laparoscopic and thoracoscopic repair Liver prolapse Abnormal liver morphology Case report

Immunotherapy for esophageal cancer:Where are we now and where can we go

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World Journal of Gastroenterology 2024年第19期30卷 2496-2501页

作者： Yoshiaki Shoji Kazuo Koyanagi Kohei Kanamori Kohei Tajima Mika Ogimi Yamato Ninomiya Miho Yamamoto Akihito Kazuno Kazuhito Nabeshima Takayuki Nishi masaki Mori Department of Gastroenterological Surgery Tokai University School of MedicineKanagawa 259-1193Japan

Immune checkpoint inhibitor therapy has dramatically improved patient prognosis,and thereby transformed the treatment in various cancer types including esophageal squamous cell carcinoma(ESCC)in the past *** antibodies that selectively inhibit programmed cell death-1(PD-1)activity has now become standard of care in the treatment of ESCC in metastatic settings,and has a high expectation to provide clinical benefit during perioperative ***,anti-cytotoxic T-lymphocyte–associated protein 4(CTLA-4)monoclonal antibody has also been approved in the treatment of recurrent/metastatic ESCC in combination with anti-PD-1 *** understanding of the existing evidence of immune-based treatments for ESCC,as well as recent clinical trials on various combinations with chemotherapy for different clinical settings including neoadjuvant,adjuvant,and metastatic diseases,may provide future prospects of ESCC treatment for better patient outcomes.

关键词： Esophageal cancer Immunotherapy Immune checkpoint inhibitor Programmed cell death-1 Anti-cytotoxic T-lymphocyte-associated protein 4 Neoadjuvant therapy Adjuvant therapy Clinical trials Combination therapy

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伊藤町零碳酒店

世界建筑导报 2024年第1期39卷 114-117页

作者： Minoru Yokoo Takumi Saikawa masaki Hamada(kkpo)(摄影) 不详

我们设计了一家零能耗酒店,作为西条市的社区中心。西条市是著名的“Uchinuki”井水产地,水源来自被视为圣山的石锤山。2016年,东京大学隈研吾实验室开始与各地的合作伙伴密切合作,以水为主题制定名为“伊藤町项目”的新型环保城市总体... 详细信息

我们设计了一家零能耗酒店,作为西条市的社区中心。西条市是著名的“Uchinuki”井水产地,水源来自被视为圣山的石锤山。2016年,东京大学隈研吾实验室开始与各地的合作伙伴密切合作,以水为主题制定名为“伊藤町项目”的新型环保城市总体规划。与当地居民举办了研讨会,为年轻建筑师举办了个人建筑竞赛,并在此基础上建立了“伊藤町”网络。

关键词：城市总体规划东京大学零能耗隈研吾酒店零碳当地居民建筑师