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Toxic Effects of Pirimiphos-methyl Residues on Rats

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Biomedical and Environmental Sciences 1989年第2期2卷 115-130页

作者： nekO K.neKOVI VESELA .KARAN VESNA SABOVLJEVI SLAVOLJUB LJ.VITOROVI Institute of Pesticides and Environmental Protection INEPBanatska 31 bPO Box 4611080 Zemun Yugoslavia Institute of Plant and Food Protection Faculty of AgricultureUniversity of BelgradeNemanjina 6PO Box 12711081 ZemunYugoslavia

This study analyzes the level of total and bound pirimiphos-methyl residues in treated wheat grain and its toxic effects on *** grain was treated with[(14)~C]pirimiphos-methyl of 16.36 mCi/mmol specific activity to determine the bioavailability of bound residues in *** the same time,grain was treated with nonlabeled pirimiphos-methyl as required to determine any possible toxic effects of bound residues in a subacute feeding study in *** dose levels were used:10 and 100 ppm(the former being the recommended dose level in practical treatment). Estimation of the type of residues was performed at intervals of 0,30,90,120,150,and 180 *** and after the animal feeding study,changes in body weight gain,organ weight, cholinesterase activity,serum enzyme activity,and hematology were *** is an indication that bound residues of the pesticide pirimiphos-methyl provoke toxic effects to some extent.1989 Academic ***.

关键词： In Toxic Effects of Pirimiphos-methyl Residues on Rats

Client views,perception and satisfaction with immunisation services at Primary Health Care Facilities in Calabar,South-South Nigeria

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Asian Pacific Journal of Tropical Medicine 2010年第4期3卷 298-301页

作者： Udonwa ne Gyuse AN Etokidem AJ Ogaji DST Department of Family Medicine University of Calabar Teaching HospitalCalabarNigeria Department of Community Medicine University of Calabar Teaching HospitalCalabarNigeria

Objective:To determine the degree of client satisfaction with immunisation services at Primary Health facilities in Calabar,Cross River State,***:A semi-structured questionnaire was administered on 402 caregivers who were selected using systematic random sampling from four primary health *** four centres were randomly selected from the 19 health centres using the table of random *** obtained were analysed using Epi-Info s of tware version ***:The majority of clients were dissatisfied with most aspects of care given at the Health Care Centres including long waiting time,accessibility of immunisation services,poor respect for clients’ rights,especially to their dignity,health information and counseling on their medical ***:The study concludes that client satisfaction with immunization service in Calabar was low due to poor attitude of health care providers,long waiting time and lack of respect for clients’ rights.

关键词： Client satisfaction Immunisation services Primary health centres

Effect of Soluble Components From Plant Aggregates on the Setting of the Lime-Based Binder

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Journal of Renewable Materials 2019年第9期7卷 903-913页

作者： Lepeng Wang Hélène Lenormand Hafida Zmamou Nathalie Leblanc UniLaSalle Transformations&Agro-Resources Research UnitVAM²IN(EA 7519 UniLaSalle-Universitéd’Artois)3 rue du Tronquet76130 Mont-Saint-AignanFrance

Plant aggregate-based building materials are a viable solution for reducing greenhouse gas emissions and providing good thermal and acoustic *** this study,the investigated lightweight mortars require a hydraulic *** and on-site empirical observations about plant aggregate-based materials indicate a delay in setting time and a decrease in the mechanical performances of concretes based on plant *** natural origin of plant-aggregates causes a lot of variability in their *** studies have shown that the incompatibility between plant aggregates and cement is mainly caused by the dissolved and decomposed components of plant aggregates in alkaline ***,no research on the specific impact of each component on the setting time of lime-based binder *** this work,the impact of some soluble compounds(e.g.,sucrose,glucose,fructose,pectin)on the setting reaction of the lime matrix was studied using Vicat test,thermogravimetric analysis(TGA)and FT-IR *** results showed that carbohydrates such as glucose and sucrose not only affect the setting time but also have a long-term impact on the carbonation of *** measure of the setting time by Vicat test appears as a possible indicator to predict the compatibility between the matrix and plant aggregates.

关键词： Plant aggregates setting time lime-based binder carbohydrates hydration

Innovation Analysis Approach to Design Parameters of High Speed Train Carriage and Their Intrinsic Complexity Relationships

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Chinese Journal of Mechanical Engineering 2017年第5期30卷 1091-1100页

作者： Shou-ne Xiao Ming-Meng Wang Guang-Zhong Hu Guang-Wu Yang State Key Laboratory of Traction Power Southwest Jiaotong University School of Mechanical Engineering Sichuan University of Science & Engineering

In view of the problem that it＇s difficult to accurately grasp the influence range and transmission path of the vehicle top design requirements on the underlying design parameters. Applying directed-weighted complex network to product parameter model is an important method that can clarify the relationships between product parameters and establish the top-down design of a product. The relationships of the product parameters of each node are calculated via a simple path searching algorithm, and the main design parameters are extracted by analysis and comparison. A uniform definition of the index formula for out-in degree can be provided based on the analysis of out- in-degree width and depth and control strength of train carriage body parameters. Vehicle gauge, axle load, crosswind and other parameters with higher values of the out-degree index are the most important boundary condi- tions; the most considerable performance indices are the parameters that have higher values of the out-in-degree index including torsional stiffness, maximum testing speed, service life of the vehicle, and so on; the main design parameters contain train carriage body weight, train weight per extended metre, train height and other parameters with higher values of the in-degree index. The network not only provides theoretical guidance for exploring the relationship of design parameters, but also further enriches the appli- cation of forward design method to high-speed trains.

关键词： Train carriage body parameters Complexnetwork Width influence Depth influence Parametercontrol strength

Natural stilbenes effects in animal models of Alzheimer’s disease

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neural Regeneration Research 2020年第5期15卷 843-849页

作者： Aline Freyssin Guylène Page Bernard Fauconneau Agnès Rioux Bilan University of Poitiers EA3808 NEUVACOD (Neurovascular Unit and Cognitive Disorders)P?le Biologie Santé

Alzheimer’s disease is one of the most frequent neurodegenerative *** pathology is characterized by protein aggregates,mainly constituted by amyloid peptide and tau,leading to neuronal death and cognitive *** currently proposed to treat this pathology do not prevent neurodegenerative processes and are mainly symptomatic ***,stilbenes presenting multiple pharmacological effects could be good potential therapeutic *** aim of this review is to gather the more significant papers among the broad literature on this topic,concerning the beneficial effects of stilbenes (resveratrol derivatives) in animal models of Alzheimer’s ***,numerous studies focus on cellular models,but an in vivo approach remains of primary importance since in animals (mice or rats,generally),bioavailability and metabolism are taken into account,which is not the case in in vitro ***,examination of memory ability is feasible in animal models,which strengthens the relevance of a compound with a view to future therapy in *** paper is addressed to any researcher who needs to study untested natural stilbenes or who wants to experiment the most effective natural stilbenes in largest animals or in *** review shows that resveratrol,the reference polyphenol,is largely studied and seems to have interesting properties on amyloid plaques,and cognitive ***,some resveratrol derivatives such as gnetin C,trans-piceid,or astringin have never been tested on ***,pterostilbene is of particular interest,by its improvement of cognitive disorders and its neuroprotective *** could be relevant to evaluate this molecule in clinical trials.

关键词： Alzheimer's disease amyloid animal models cognitive impairment inflammation natural stilbenes neuroprotection resveratrol tau

Climatology of yellow sand (Asian sand, Asian dust or Kosa) in East Asia

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Science China Earth Sciences 2002年第z1期45卷 59-70页

作者： Masatoshi Yoshino poplar.ocn.ne.jp) Tsukuba University Setagayaku Tokyo 154-0012 Japan (email: mtoshiyo

In order to study climatology of yellow sand (Asian sand, Asian dust or Kosa) in EastAsia, secular fluctuation in China, Korea and Japan in the recent 30 years was presented. Thenumber of days with sand-dust storm at five stations in China-Hotan, Zhangye, Minqin, Jurhand Beijing, decreases a lot at the former three stations, but changed little at the latter two *** that the recent global warming is more evident in Xinjiang and Gansu, where the fre-quency of cold air invasions from the higher latitudes is decreasing. But, the eastern parts ofMongolia, inner Mongolia, and North China encounter stronger cyclones in early spring as a resultof global warming. These cyclones bring cold air from higher latitudes, causing severe duststorms. Secular variation in the annual days with sand-dust storms in China and Kosa days in Ko-rea and Japan show a parallel change with higher frequency from 1975 to 1985. This may be re-lated to the higher frequency of La Nina years. However, different tendency was shown in theperiod from 1986 to 1996. Since 1996 or 1997, a sharp increase is clear, which may be caused bythe developed cyclones in East Asia as well as human activities, and stronger land degradationunder La Nina conditions. Anomalies of the total number of stations with Kosa days were dis-cussed in accordance with some synoptic meteorological conditions such as the differences be-tween Siberian anticyclone and Aleutian cyclone center at 500 hPa level during the previous winter.

关键词： Aeolian dust transport, Asian dust, sand, Kosa, sand-dust storm.

Natural polyphenols effects on protein aggregates in Alzheimer＇s and Parkinson＇s prion-like diseases

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neural Regeneration Research 2018年第6期13卷 955-961页

作者： aline freyssin guylène page bernard fauconneau agnès rioux bilan University of Poitiers EA380-8 NEUVACOD (Neurovascular Unit and Cognitive Disorders) Pole Biologie Sante Poitiers France

Alzheimer＇s and Parkinson＇s diseases are the most common neurodegenerative diseases. They are characterized by protein aggregates and so can be considered as prion-like disease. The major components of these deposits are amyloid peptide and tau for Alzheimer＇s disease, α-synuclein and synphilin-1 for Parkinson＇s disease. Drugs currently proposed to treat these pathologies do not prevent neurodegenerative processes and are mainly symptomatic therapies. Molecules inducing inhibition of aggregation or disaggregation of these proteins could have beneficial effects, especially if they have other beneficial effects for these diseases. Thus, several natural polyphenols, which have antioxidative, anti-inflammatory and neuroprotective properties, have been largely studied, for their effects on protein aggregates found in these diseases, notably in vitro. In this article, we propose to review the significant papers concerning the role of polyphenols on aggregation and disaggregation of amyloid peptide, tau, α-synuclein, synphilin-1, suggesting that these compounds could be useful in the treatments in Alzheimer＇s and Parkinson＇s diseases.

关键词： natural polyphenols protein aggregates Alzheimer's disease amyloid peptide amyloid plaques hyperphosphorylated tau Parkinson's disease a-synuclein synphilin-I

Steady State Analysis of an Isolated Self-Excited Dual Three-Phase Induction Generator for Renewable Energy

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International Journal of Modern Nonlinear Theory and Application 2014年第5期3卷 191-198页

作者： Mohamed arbi Khlifi Badr M. Alshammari College of Engineering Hail University Hail KSA

In this paper modelling and analysis in autonomous mode of dual three-phase induction generator (DTPIG) with a new algorithm have been done. We develop the steady state model of a dual three-phase self-excited induction generator for stand-alone renewable generation dispensing with the segregating real and imaginary components of the complex impedance of the induction generator. The obtained admittance yields the adequate magnetizing reactance and the frequency. These two key parameters are then used to compute the self-excitation process requirements in terms of the prime mover speed, the capacitance and the load impedance on the one hand and to predict the generator steady state performance parameters on the other. Steady state performances and characteristics of different configurations are clearly examined and compared. The analytical results are found to be in good agreement with experimental results.

关键词： Dual Stator Windings Asynchronous Generator Autonomous Mode Steady State Analysis Renewable Electric Energy Generation

The Sav-AQ Project:Study of Obstacles and Levers Related to the Use of a Website Dedicated to Breast Cancer Patients;the Example of the Nouvelle-Aquitaine Region

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Psycho-Oncologie 2023年第3期17卷 159-166页

作者： Valérie Berger Hélène Hoarau Florence Saillour Unitéde Recherche et d’Innovation et Soins et en Sciences Humaines(URISH) CHU de BordeauxBordeaux33000France Laboratoire Culture et Diffusion des Savoirs(CeDS) Universitéde BordeauxBordeaux33000France Pôle santépublique Méthodes d’évaluation en santé(UMES) CHU BordeauxBordeaux33000France ISPED Centre INSERM U1219Bordeaux Population Health–UnitéPHARes FUniversity de BordeauxBordeaux33000France

The development of digital platforms is transforming caregiver-patient interactions and the dissemination of *** information from the Internet has become a habit for many patients and must be considered by ***,understanding the use of digital tools by patients is a public health *** Sav-AQ study aims to understand patterns of use by women with breast cancer and the role of health ***-AQ is an exploratory feasibility study with a mixed design,exploring patient and healthcare experience before and after the integration of a specific website into their care *** research is based on the digital platform“My Breast Cancer network”,which was built by and for patients with breast cancer.A group of 30 breast cancer patients and six healthcare professionals using the platform were *** results show that for all users,the activity on the website decreases over *** the beginning of the course,patients were more assiduous,which can be explained by the search for elements related to an unknown care *** results also show that technical skills to use the platform are necessary for patients and must be accompanied by a health *** is of interest to devise a larger study to assessing the impact of such a platform on patient healthcare uptake and health skills development.

关键词： Breast cancer knowledge transfer interdisciplinarity digital health