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Mindfulness training in medical education as a means to improve resilience,empathy,and mental health in the medical profession

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World Journal of Psychiatry 2024年第4期14卷 489-493页

作者： Edison iglesias de Oliveira Vidal Luiz Fernando Alvarenga Ribeiro Marco antonio de Carvalho-Filho Fernanda Bono Fukushima Internal Medicine Department Botucatu Medical SchoolSao Paulo State University(UNESP)Botucatu 18618-687SPBrazil Wenckebach Institute for Education and Training LEARN-Lifelong LearningEducation and Assessment Research NetworkUniversity Medical Center GroningenGroningen 9713AVGroningenNetherlands Assertiva Mindfulness Botucatu 18603-970SPBrazil Surgical Specialties and Anesthesiology Department Botucatu Medical SchoolSão Paulo State University(UNESP)Botucatu 18618-687SPBrazil

The high rates of depression,burnout,and increased risk of suicide among medical students,residents,and physicians in comparison with other careers signal a mental health crisis within our *** contend that this crisis coupled with the inadequate acquisition of interpersonal skills during medical education results from the interaction between a challenging environment and the mental capital of ***,we posit that mindfulness-based practices are instrumental for the development of major components of mental capital,such as resilience,flexibility of mind,and learning skills,while also serving as a pathway to enhance empathy,compassion,self-awareness,conflict resolution,and relational ***,the evidence base supporting the effectiveness of mindfulness-based interventions has been increasing over the years,and a growing number of medical schools have already integrated mindfulness into their *** we acknowledge that mindfulness is not a panacea for all educational and mental health problems in this field,we argue that there is currently an unprecedented opportunity to gather momentum,spread and study mindfulness-based programs in medical schools around the world as a way to address some longstanding shortcomings of the medical profession and the health and educational systems upon which it is rooted.

关键词： Mindfulness Medical education Mental capital Mental health Medical students Resilience

旋转输运速度场积分SPH对流扩散方程解的收敛性

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Acta Mechanica Sinica 2023年第2期39卷 61-70页

作者： Pablo Eleazar Merino-Alonso Fabricio Macià antonio Souto-iglesias Departamento de Arquitectura Constructión y Sistemas Oceánicos y NovalesUniversidad Politécnica de MadridMadridSpain Departamento de Matemática e Informática Aplicadas a las Ingenierías Civil y Naval Universidad Politécnica de MadridMadridSpain

本文在刚性旋转输运速度场的特殊情况下,建立了二维平流扩散方程的积分光滑粒子流体动力学(SPH)解的收敛性.考虑了Morris等人对拉普拉斯算子的近似,在傅里叶空间中建立了SPH解与精确解的收敛性.证明了如果满足核的傅里叶变换的某个条件... 详细信息

本文在刚性旋转输运速度场的特殊情况下,建立了二维平流扩散方程的积分光滑粒子流体动力学(SPH)解的收敛性.考虑了Morris等人对拉普拉斯算子的近似,在傅里叶空间中建立了SPH解与精确解的收敛性.证明了如果满足核的傅里叶变换的某个条件,即我们称之为正条件,则收敛是有保证的.这个条件是核的傅里叶变换其径向轮廓的一阶矩为正,并通过数值验证说明了分析结果.根据L2范数和最大范数,比较了使用不同核包括SPH社区更常用的核(即Wendland核以及三次和线性样条核)获得的数值解.除此之外,提出并测试了一个病理核,该核不满足正条件,导致了非收敛结果.这一事实表明,在对流扩散方程的情况下,正条件不仅是收敛的充分条件,也是必要条件.

关键词： Smoothed particle hydrodynamics Numerical analysis Diffusion Convergence Fourier analysis

Technological trajectory based on micro level technological capability:Evidence from the Brazilian rice industry

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International Journal of Innovation Studies 2022年第3期6卷 196-215页

作者： Monica Fitz-Oliveira Jorge Tello-gamarra Institute of Economic Administrative and Accounting SciencesFederal University of Rio GrandeRio Grande96203-900Brazil School of Chemistry and Food Federal University of Rio GrandeSanto.Antonio da Patrulha95500-000Brazil School of Administration Federal University of Rio Grande do SulPorto Alegre90010-460Brazil

This study examines technological capability accumulation and the Brazilian rice industry's technological *** case design was chosen,with an analysis of seven firms involved in the Brazilian rice *** results indicate three factors:The first was the identification of technological landmarks for firms in this sector(peeling and polishing,electronic grain selection,electronic packaging,use of forklifts and palletizers,and Industry 4.0).The second is related to the fact that different firms implemented innovative activities and technologies at different speeds,originating from the sector's different technological *** third is associated with identifying activities within the Brazilian rice industry that can be generalized to other food *** results have implications for formulating public policies in the sector,such as creating producer support mechanisms(research and technology transfer institutions),qualification of professionals,and encouragement for economic efficiency and competition.

关键词： Technological capability Technological trajectory Firm Industry Innovation Rice

On the numerical solution to the truncated discrete SPH formulation of the hydrostatic problem

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Journal of Hydrodynamics 2020年第4期32卷 699-709页

作者： Pablo Eleazar Merino-Alonso Fabricio Macia antonio Souto-iglesias Mathematical Modeling Analysisand Simulation Applied to Engineering Research Group(M2ASAI)Universi dad politecnica de Madrid(UPM)School of marine engineering(ETSIN)MadridSpain Marine and Hydrodynamical Model Basin Research Group(CEHINAV) Universidad Politecnica de Madrid(UPM)School of Marine Engineering(ETSIN)MadridSpain

The aim of this work is to study the solution of the smoothed particle hydrodynamics(SPH)discrete formulation of the hydrostatic problem with a free *** problem,in which no time dependency is considered,takes the form of a system of linear *** particular,the problem in one dimension is *** focus is set on the convergence when both the particle spacing and the smoothing length tend to zero by keeping constant their *** of this ratio of the order of one,corresponding to a limited number of neighbors,are of practical ***,the problem in which each particle has one single neighbor at each side is *** explicit expressions of the numerical solution and the quadratic error are provided in this *** expression of the quadratic error demonstrates that the SPH solution does not converge to the exact one in general under the specified *** this case,the error converges to a residue,which is in general large compared to the norm of the exact *** cases with two and three neighbors are also *** analytical study in the case of two neighbors is performed,showing how the kernel influences the accuracy of the solution through modifying the condition number of the referred system of linear *** addition to that,a numerical investigation is carried out using several Wendland kernel *** two and three neighbors are involved it is found that the error tends in most cases to a small limiting value,different from zero,while divergent solutions are also found in the case of two neighbors with the Wendland Kernel *** cases with more neighbors are also *** general,the Wendland Kernel C2 turns out to be the worst choice,as the solution is divergent for certain values of the ratio between the particle spacing and the smoothing length,associated with an ill-conditioned matrix.

关键词： Smoothed particle hydrodynamics(SPH) convergence water-at-rest problem hydrostatic tank,free surface kernel truncation

The ability of sperm selection techniques to remove single- or double-strand DNA damage

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Asian Journal of Andrology 2011年第5期13卷 764-768页

作者： Maria Enciso Miriam iglesias Isabel Galan Jonas Sarasa antonio Gosalvez Jaime Gosalvez Unidad de Genetica Departamento de Biologia Universidad Aut6noma de Madrid Madrid 28049 Spain Unidad de Reproducci6n Asistida Hospital Quir6n Madrid Madrid 28223 Spain

A wide variety of techniques for the preparation of sperm are currently available, of which the most commonly employed are densitygradient centrifugation （DGC） and swim-up （SUP）. To date, these methods appear to be effective in selecting functional sperm for assisted reproduction techniques （ART）, but they may have negative effects on sperm DNA. In this study, the ability of these semen processing techniques to eliminate spermatozoa containing single- and double-strand DNA damage was assessed by the two-tailed comet assay and the sperm chromatin dispersion test in 157 semen samples from patients seeking assisted reproduction treatment. Our results indicated that SUP and DGC are equally efficient in eliminating spermatozoa containing double-strand DNA damage and sperm with highly damaged （degraded） DNA, as characterized by the presence of both single- and double-strand DNA breaks. However, DGC is more efficient than SUP in selecting spermatozoa that are free from single-strand DNA damage. Future studies should characterise the importance of the various types of DNA damage and examine the sperm processing protocols used in each laboratory to determine their ability to eliminate DNA damage and hence, prevent the potential transmission of genetic mutations via ART.

关键词： density-gradient centrifugation male factor sperm chromatin dispersion sperm DNA fragmentation swim-up

Hepatitis C: Problems to extinction and residual hepatic and extrahepatic lesions after sustained virological response

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World Journal of Hepatology 2022年第1期14卷 62-79页

作者： Sara Cuesta-Sancho Mercedes Márquez-Coello Francisco Illanes-Álvarez Denisse Márquez-Ruiz Ana Arizcorreta Fátima Galán-Sánchez Natalia Montiel Manuel Rodriguez-iglesias José-antonio Girón-González Medicina Interna Hospital Universitario Puerta del MarFacultad de MedicinaUniversidad de CádizInstituto para la Investigación e Innovación en Ciencias Biomédicas de Cádiz(INiBICA)Cádiz 11009Spain Microbiología Hospital Universitario Puerta del MarFacultad de MedicinaUniversidad de CádizInstituto para la Investigación e Innovación en Ciencias Biomédicas de Cádiz(INiBICA)Cádiz 11009Spain

Loss of follow-up or reinfections hinder the expectations of hepatitis C eradicationdespite the existence of highly effective treatments. Moreover, the elimination ofthe infection does not imply the reversion of those chronic alterations derivedfrom the previous infection by hepatitis C virus (HCV). This review analyzes therisk factors associated with loss to follow-up in diagnosis or treatment, and thepossibility of reinfection. Likewise, it assesses the residual alterations induced bychronic HCV infection considering the liver alterations (inflammation, fibrosis,risk of decompensation, hepatocellular carcinoma, liver transplantation) and, onthe other hand, the comorbidities and extrahepatic manifestations (cryoglobulinemia,non-Hodgkin lymphoma, peripheral insulin resistance, and lipid, boneand cognitive alterations). Peculiarities present in subjects coinfected with humanimmunodeficiency virus are analyzed in each section.

关键词： Hepatitis C virus Sustained virological response Direct antiviral agents Human immunodeficiency virus Cirrhosis decompensation Hepatocarcinoma Extrahepatic complications

Morphometrics confirms the conspecific between Blaptica dubia(Serville) and B. interior Hebard(Blattodea:Blaberidae)

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Zoological Systematics 2019年第2期44卷 111-122页

作者： María Marta González Alejandra del Carmen Valverde Mónica Sandra iglesias Francisco antonio Crespo Laboratorio de Artrópodos Departamento de Biodiversidad y Biología Experimental Facultad de Ciencias Exactas y Naturales Universidad de Buenos Aires Pabellón Ⅱ Ciudad Universitaria Centro de diagnóstico e investigación en endemo-epidemias. Administración nacional de laboratorios e institutos de salud "Dr. Carlos G. Malbrán"

Blaptica dubia(Serville, 1838) and B. interior Hebard, 1921 were considered to be cryptic species. The characteristics originally proposed for their identification are not *** the relationship between the two species should be re-considered. As a comparative approach and to analyze intraspecific variability, morphological and morphometric methods were performed. Traditional and new characters such as wing shape and pronotum contour were utilized. We found significant differences between both species(p <0.05) in the shape of the wing, but there was an overlap of values. We did not find differences in the body measurements or in the shape and size of the pronotum between the species. The variability gradient does not allow an accurate identification of species neither with the male genitalia or the pronotal *** on the obtained results, B. interior Hebard 1921 is considered to be a junior synonym of B. dubia(Serville, 1838).

关键词： Cockroaches pronotum genitalia geometric morphometric analysis synonymy

Impact of endoscopic ultrasound-guided fine needle biopsy for diagnosis of pancreatic masses

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World Journal of Gastroenterology 2007年第2期13卷 289-293页

作者： Julio iglesias-Garcia Enrique Dominguez-Munoz antonio Lozano-Leon Ihab Abdulkader Jose Larino-Noia Jose Antunez Jeronimo Forteza Gastroenterology Department University Hospital Santiago de Compostela Spain Foundation for Research in Digestive Diseases Santiago de Compostela Spain Foundation for Research in Digestive Diseases Santiago de Compostela Spain Pathology Department University Hospital Santiago de Compostela Spain

AIM: To evaluate the diagnostic accuracy of histologi- cal evaluation of pancreatic tissue samples obtained by a modified method for recovering and processing the endoscopic ultrasound (EUS)-guided fine needle aspira- tion (FNA) material in the differential diagnosis of pan- creatic solid masses. METHODS: Sixty-two consecutive patients with pan- creatic masses were prospectively studied. EUS was performed by the linear scanning Pentax FG-38UX ech- oendoscope. Three FNAs (22G needle) were carried out during each procedure. The materials obtained with first and second punctures were processed for cytological study. Materials of the third puncture were recovered into 10% formol solution by careful injection of saline so- lution through the needle, and processed for histological study. RESULTS: Length of the core specimen obtained for his- tological analysis was 6.5 ± 5.3 mm (range 1-22 mm). Cytological and histological samples were considered as adequate in 51 (82.3%) and 52 cases (83.9%), respec- tively. Overall sensitivity of both pancreatic cytology and histology for diagnosis of malignancy was 68.4%. Con- trary to cytology, histology was able to diagnose tumours other than adenocarcinomas, and all cases of inflamma- tory masses. Combination of cytology and histology al- lowed obtaining an adequate sample in 56 cases (90.3%), with a global sensitivity of 84.21%, specificity of 100% and an overall accuracy of 90.32%. The complication rate was 1.6%.CONCLUSION: Adequate pancreatic core specimens forhistological examination can be obtained by EUS-guided FNA. This technique is mainly useful for the diagnosis of different types of pancreatic tumours and evaluation of benign diseases.

关键词：胰腺炎组织病理学活组织检查诊断方法

Multimodality functional imaging using DW-MRI and 18F-FDG-PET/CT during radiation therapy for human papillomavirus negative head and neck squamous cell carcinoma: Meixoeiro Hospital of Vigo Experience

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World Journal of Radiology 2017年第1期9卷 17-26页

作者： David Aramburu Núnez antonio Lopez Medina Moisés Mera iglesias Francisco Salvador Gomez Abhay Dave Vaios Hatzoglou Ramesh Paudyal Alfonso Calzado Joseph O Deasy Amita Shukla-Dave Victor M Munoz Department of Medical Physics and Radiological Protection Galaria - MeixoeiroUniversity Hospital Complex of Vigo Department of Medical Physics Memorial Sloan-Kettering Cancer Center Department of Radiology Complutense University Department of Medical Physics Department of Radiology Memorial Sloan-Kettering Cancer Center Department of Radiation Oncology Galaria - MeixoeiroUniversity Hospital Complex of Vigo

AIM To noninvasively investigate tumor cellularity measured using diffusion-weighted magnetic resonance imaging(DW-MRI) and glucose metabolism measured by 18 Flabeled fluorodeoxyglucose positron emission tomography/computed tomography(18F-FDG-PET/CT) during radiation therapy(RT) for human papillomavirus negative(HPV-) head and neck squamous cell carcinoma(HNSCC).METHODS In this prospective study, 6 HPV- HNSCC patients underwent a total of 34 multimodality imaging examinations(DW-MRI at 1.5 T Philips MRI scanner [(n = 24) pre-, during-(2-3 wk), and post-treatment(Tx), and 18F-FDG PET/CT pre- and post-Tx(n = 10)]. All patients received RT. Monoexponential modeling of the DW-MRI data yielded the imaging metric apparent diffusion coefficient(ADC) and the mean of standardized uptake value(SUV) was measured from 18F-FDG PET uptake. All patients had a clinical follow-up as the standard of care and survival status was documented at 1 *** There was a strong negative correlation between the mean of pretreatment ADC(ρ =-0.67, P = 0.01) and the pretreatment 18F-FDG PET SUV. The percentage(%) change in delta(?) ADC for primary tumors and neck nodal metastases between pre- and Wk2-3 Tx were as follows: 75.4% and 61.6%, respectively, for the patient with no evidence of disease, 27.5% and 32.7%, respectively, for those patients who were alive with disease, and 26.9% and 7.31%, respectively, for those who were dead with *** These results are preliminary in nature and are indicative, and not definitive, trends rendered by the imaging metrics due to the small sample size of HPV- HNSCC patients in a Meixoeiro Hospital of Vigo Experience.

关键词：散开加权的磁性的回声成像人的乳头状瘤病毒否定的头和颈有鳞的房间癌 18标记 F 的 fluorodeoxyglucose 正电子排放 tomography/computed 断层摄影术