检索结果-南通市图书馆

Impulse magnetic stimulation facilitates synaptic regeneration in rats following sciatic nerve injury

Neural Regeneration Research 2012年第17期7卷 1299-1303页

作者： Sergey A.Zhivolupov Miroslav M.Odinak Nariman A.Rashidov Ludmila S.Onischenko Igor N.Samartsev anton a.jurin Department of Neurology Military-Medical AcademySaint-Petersburg194044Lesnoy prospect 2Russian Federation

The current studies describing magnetic stimulation for treatment of nervous system diseases mainly focus on transcranial magnetic stimulation and rarely focus on spinal cord magnetic stimulation. Spinal cord magnetic stimulation has been confirmed to promote neural plasticity after injuries of spinal cord, brain and peripheral nerve. To evaluate the effects of impulse magnetic stimulation of the spinal cord on peripheral nerve regneration, we compressed a 3 mm segment located in the middle third of the hip using a sterilized artery forceps to induce ischemia. Then, all animals underwent impulse magnetic stimulation of the lumbar portion of spinal crod and spinal nerve roots daily for 1 month. Electron microscopy results showed that in and below the injuryed segment, the inflammation and demyelination of neural tissue were alleviated, apoptotic cells were reduced, and injured Schwann cells and myelin fibers were repaired. These findings suggest that high-frequency impulse magnetic stimulation of spinal cord and corresponding spinal nerve roots promotes synaptic regeneration following sciatic nerve injury.

关键词： impulse magnetic stimulation experimental neuropathy sciatic nerve lesion neuroplasticity neuralregeneration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

流感与COVID-19患者的免疫球蛋白G糖基化差异

引用

Engineering 2023年第7期26卷 54-62,I0003页

作者： Marina Kljakovic-Gašpic Batinjan Tea Petrovic Frano Vuckovic Irzal Hadz ibegovic Barbara Radovani Ivana.jurin LovorkaÐerek Eva Huljev Alemka Markotic Ivica Lukšic Irena Trbojevic´-Akmacic Gordan Lauc Ivan Gudelj Rok Civljak University Hospital Centre Zagreb Zagreb 10000Croatia Genos Glycoscience Research Laboratory Zagreb 10000Croatia Department of Cardiology University Hospital DubravaZagreb 10000Croatia Faculty of Dental Medicine and Health Josip Juraj Strossmayer UniversityOsijek 31000Croatia Department of Biotechnology University of RijekaRijeka 51000Croatia Department for Laboratory Diagnostics University Hospital DubravaZagreb 10000Croatia Department for Acute Respiratory Infections University Hospital for Infectious Diseases“Dr.Fran Mihaljevic”Zagreb 10000Croatia Department for Urogenital Infections University Hospital for Infectious Diseases“Dr.Fran Mihaljevic”Zagreb 10000Croatia Department for Infectious Diseases School of MedicineCatholic University of Croatia10000 ZagrebCroatia Postdoctoral Study Faculty of MedicineUniversity of RijekaRijeka 51000Croatia Department of Maxillofacial Surgery University of Zagreb School of MedicineDubrava University HospitalZagreb 10000Croatia Faculty of Pharmacy and Biochemistry University of ZagrebZagreb 10000Croatia Department of Infectious Diseases University of Zagreb School of MedicineZagreb 10000Croatia

The essential role of immunoglobulin G(IgG)in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the fragment crystallizable(Fc)domain that occur under such *** glycans impact the antibody stability,half-life,secretion,immunogenicity,and effector ***,in this study,we analyzed and compared the total IgG glycome—at the level of individual glycan structures and derived glycosylation traits(sialylation,galactosylation,fucosylation,and bisecting Nacetylglucosamine(GlcNAc))—of 64 patients with influenza,77 patients with coronavirus disease 2019(COVID-19),and 56 healthy *** study revealed a significant decrease in IgG galactosylation,sialylation,and bisecting GlcNAc(where the latter shows the most significant decrease)in deceased COVID19 patients,whereas IgG fucosylation was *** the other hand,IgG galactosylation remained stable in influenza patients and COVID-19 *** glycosylation in influenza patients was more time-dependent:In the first seven days of the disease,sialylation increased and fucosylation and bisecting GlcNAc decreased;in the next 21 days,sialylation decreased and fucosylation increased(while bisecting GlcNAc remained stable).The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses,while the observed changes in deceased COVID-19 patients may indicate its deviation.

关键词： Influenza COVID-19 Viral infection Glycosylation Immunoglobulin G Pneumonia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

流感与COVID-19患者的免疫球蛋白G糖基化差异（英文）

引用

Engineering 2023年第7期 54-62页

作者： Marina Kljakovi?-Ga?pi? Batinjan Tea Petrovi? Frano Vu?kovi? Irzal Had?ibegovi? Barbara Radovani Ivana.jurin Lovorka Derek Eva Huljev Alemka Markoti? Ivica Luk?i? Irena Trbojevi?-Akma?i? Gordan Lauc Ivan Gudelj Rok ?ivljak University Hospital Centre Zagreb Genos Glycoscience Research Laboratory Department of Cardiology University Hospital Dubrava Faculty of Dental Medicine and Health Josip Juraj Strossmayer University Department of Biotechnology University of Rijeka Department for Laboratory Diagnostics University Hospital Dubrava Department for Acute Respiratory Infections University Hospital for Infectious Diseases “Dr. Fran Mihaljevi?” 8. Department for Urogenital Infections University Hospital for Infectious Diseases “Dr. Fran Mihaljevi?” 9. Department for Infectious Diseases School of Medicine Catholic University of Croatia Postdoctoral Study Faculty of Medicine University of Rijeka Department of Maxillofacial Surgery University of Zagreb School of Medicine Dubrava University Hospital Faculty of Pharmacy and Biochemistry University of Zagreb Department of Infectious Diseases University of Zagreb School of Medicine

The essential role of immunoglobulin G(IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the fragment crystallizable(Fc) domain that occur under such *** glycans impact the antibody stability, half-life, secretion, immunogenicity, and effector ***, in this study, we analyzed and compared the total IgG glycome—at the level of individual glycan structures and derived glycosylation traits(sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine(GlcNAc))—of 64 patients with influenza, 77 patients with coronavirus disease 2019(COVID-19), and 56 healthy controls. Our study revealed a significant decrease in IgG galactosylation, sialylation, and bisecting GlcNAc(where the latter shows the most significant decrease) in deceased COVID-19 patients, whereas IgG fucosylation was increased. On the other hand, IgG galactosylation remained stable in influenza patients and COVID-19 survivors. IgG glycosylation in influenza patients was more time-dependent: In the first seven days of the disease, sialylation increased and fucosylation and bisecting GlcNAc decreased; in the next 21 days, sialylation decreased and fucosylation increased(while bisecting GlcNAc remained stable). The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

在采矿作业中透水岩石密封的综合方法

引用

有色矿山 1989年第6期18卷 26-31页

作者： ErnestJ.Kipko jurin.Spichak 张信德

在苏联发展了一种新的透水岩石密封的方法,本方法是在开拓井巷和旧巷道采空矿房的充填中发展起来的,并已在200多个项目的实施过程中证实成绩卓著.此方法是以对透水岩石密封的整个过程进行的经济技术计算为依据。密封是用一种新的,有效... 详细信息

在苏联发展了一种新的透水岩石密封的方法,本方法是在开拓井巷和旧巷道采空矿房的充填中发展起来的,并已在200多个项目的实施过程中证实成绩卓著.此方法是以对透水岩石密封的整个过程进行的经济技术计算为依据。密封是用一种新的,有效并便宜的密封泥浆来实现的,此泥浆主要用粘土和砂质粘土制备.本文对密封方法的使用成果加以介绍。

关键词：采矿作业透水岩石密封法

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

环境通讯

引用

国外科技新书评介 2011年第11期 9-9页

作者： Richard R．jurin（等）鲁敏不详中国科学院动物研究所

可持续发展是不以牺牲人类所依赖的环境为代价，是不以破坏生物圈其它组成成分为代价的。本书的主要目的是增加作为环境通讯者的人类与环境和谐相处的知识和技巧。

关键词：环境通讯可持续发展组成成分和谐相处生物圈人类

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：