检索结果-南通市图书馆

现代外国哲学社会科学文摘 1961年第11期 32-33页

作者：理查逊方同源

输证精神分析时所遇到的最大困难,象弗洛伊德本人所指出的,是在于精神分析活动的过程中,本质上有它的主观性。除非你本人自己具有精神分析的经验,这就意味着具有相当广泛的不受拘束的联想实习经验,因而即使看来同当前活动无关的,细小

关键词：弗洛伊德勃朗逊克

Women on the liver transplantation waitlist are at increased risk of hospitalization compared to men

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2019年第8期25卷 980-988页

作者： Jessica B Rubin Marie Sinclair Robert S Rahimi Elliot B Tapper Jennifer c Lai Division of Gastroenterology and Hepatology Department of MedicineUniversity of California-San FranciscoSan FranciscoCA 94143 United States Department of Gastroenterology and Hepatology Austin HealthHeidelberg 3084VictoriaAustralia Department of Medicine the University of MelbourneMelbourne 3010VictoriaAustralia Division of Hepatology Annette C.and Harold C.Simmons Transplant InstituteBaylor University Medical CenterDallasTX 75346United States Division of Gastroenterology and Hepatology University of MichiganAnn ArborMI 48109United States

BAcKGROUND Hospital admissions are common among patients with cirrhosis,but patient factors associated with hospitalization have not been well *** recent data suggesting increased liver transplant waitlist dropout among women,we hypothesized that women on the liver transplant waitlist would have increased rates of hospitalization compared with *** To evaluate the role of gender on risk of hospitalization for patients on the liver transplant waitlist,in order to help explain gender disparities in waitlist *** Patients listed for liver transplant at a single center in the United States were prospectively enrolled in the Functional Assessment in Liver Transplantation *** included in this retrospective analysis included those enrolled between March 2012 and December 2014 with at least 12 mo of follow up and without hepatocellular *** primary and secondary outcomes were hospitalization and total inpatient days within 12 mo,*** and negative binomial regression associated baseline factors with *** Of the 392 patients,41%were female,with median(interquartile range)age 58 years(52-63)and model for end-stage liver disease 18(15-22).Within 12 mo,186(47%)patients were hospitalized≥1 time;48%were readmitted,with a median of 8(4-15)inpatient *** women than men were hospitalized(54%vs 43%;P=0.03).In univariable analysis,female sex was associated with an increased risk of hospitalization[odds ratios(OR)1.6,95%confidence interval(cI)1.0-2.4;P=0.03],which remained significant on adjusted multivariable analysis(OR 1.6,95%cI:1.1-2.6;P=0.03).Female gender was also associated with an increased number of inpatient days within 12 mo in both univariable and multivariable *** Women with cirrhosis on the liver transplant waitlist have more hospitalizations and inpatient days in one year compared with men,suggesting that the experience of cirrhosis differs between men and women,despite

关键词： Gender cirrhosis Liver transplantation waitlist Hospitalization Readmission Women

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

成功销售手册英汉对照

comparison of Yeast Viability/Vitality Methods and Their Relationship to Fermentation Performance

丛书名：职业成功必读书架

2006年

作者：（美）琳达·理查德森（Linda richardson）施淑芳译

本书介绍了6个销售计划，介绍了如何聆听并了解顾客的意见，如何成功地和精明顾客交易，以及如何针对顾客意见提出解决问题的销售建议。

ISBN: (纸本)7302123632

本书介绍了6个销售计划，介绍了如何聆听并了解顾客的意见，如何成功地和精明顾客交易，以及如何针对顾客意见提出解决问题的销售建议。

关键词：企业管理销售管理

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

中外酒业 2020年第9期 47-54页

作者： L.R.WHITE K.E.richardson A.J.ScHIEWE c.E.WHITE 不详

In the brewhouse,consistent beer production is the ultimate *** brewers implement techniques and methods to curb *** over raw ingredients,sanitation,fermentation and packaging is *** yeast lends tremendous flavour and character to beer,brewers attempt to determine yeast quality by measurement of its viability and/or its *** the physiological condition of yeast is useful informaton for creating a consistent product.

关键词： Yeast desired creating

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

猪细小病毒疫苗的效力试验

贵州畜牧兽医 1997年第4期21卷 41-43页

作者： K.R.Edwards M.A.Emmerson P.R.Luff D.E.Wells J.c.Muskett.A.E.Wrtahall c.richardson B.N.J.Parker D.H.Thornton 陈眷华

本次研究旨在调查和比较3种不同疫苗所提供的避免胎儿死亡的保护力,其中两种疫苗采用3个不同的剂量接种,以期能够获得不同的保护水平,以半数保护剂量(PD_(50))表示,由此获得的数据可以对其它疫苗作出评价。同时,对在已建立的细胞系上增... 详细信息

本次研究旨在调查和比较3种不同疫苗所提供的避免胎儿死亡的保护力,其中两种疫苗采用3个不同的剂量接种,以期能够获得不同的保护水平,以半数保护剂量(PD_(50))表示,由此获得的数据可以对其它疫苗作出评价。同时,对在已建立的细胞系上增殖病毒。

关键词：猪病细小病毒病疫苗免疫接种

帕博利珠单抗治疗伴脑转移NScLc患者的一项非随机、开放Ⅱ期试验的长期随访结果和生物标志物分析

在线全文

学校读者我要写书评

暂无评论

中国肺癌杂志 2021年第9期24卷 I0007-I0016页

作者： Sarah B GOLDBERG Kurt A ScHALPER Scott N GETTINGER Amit MAHAJAN Roy S HERBST Anne c cHANG Rogerio LILENBAUM Frederick H WILSON Sacit Bulent OMAY James B YU Lucia JILAVEANU Thuy TRAN Kira PAVLIK Elin ROWEN Heather GERRSH annette KOMLO Richa GUPTA Hailey WYATT Matthew RIBEIRO Yuval KLUGER Geyu ZHOU Wei WEI Veronica L cHANG Harriet M KLUGER 董晓荣(翻译/校对) Department of Medicine(Medical Oncology) Yale School of MedicineNew HavenCTUSA Department of Pathology Yale School of MedicineNew HavenCTUSA Department of Radiology Yale School of MedicineNew HavenCTUSA Department of Neurosurgery Yale School of MedicineNew HavenCTUSA Department of Therapeutic Radiology Yale School of MedicineNew HavenCTUSA Interdepartmental Program in computational Biology and Bioinformatics Yale School of MedicineNew HavenCTUSA Department of Biostatistics Yale School of Public HealthNew HavenCTUSA 华中科技大学同济医学院附属协和医院胸部肿瘤科

背景与目的我们开展了一项帕博利珠单抗用于伴未治疗脑转移的非小细胞肺癌(non-small cell lung cancer,NScLc)或黑色素瘤患者的疗效和安全性的II期试验,旨在评估程序性死亡受体1(programmed cell death 1,PD-1)抑制剂在中枢神经系统(ce... 详细信息

背景与目的我们开展了一项帕博利珠单抗用于伴未治疗脑转移的非小细胞肺癌(non-small cell lung cancer,NScLc)或黑色素瘤患者的疗效和安全性的II期试验,旨在评估程序性死亡受体1(programmed cell death 1,PD-1)抑制剂在中枢神经系统(central nervous system,cNS)中的疗效。中期结果已发表,现报道对NScLc队列的更新分析结果。方法这是一项开放性、单中心、II期试验。纳入标准:年龄≥18岁,诊断为晚期NScLc并伴有≥1个5 mm-20 mm脑转移病灶,既往从未治疗或之前放疗后进展,无神经系统症状,不需要激素治疗且美国东部肿瘤协作组(Eastern cooperative Oncology Group,EcOG)cell death ligand 1,PD-L1)≥1%的患者,队列2为PD-L1cT02085070。结果2014年3月31日-2018年5月21日,共42例患者接受治疗。中位随访时间为8.3个月(IQR:4.5个月-26.2个月)。队列1的37例患者中11例有脑转移缓解[29.7%(95%cI:15.9%-47.0%)]。队列2未观察到缓解。治疗相关的3级-4级不良事件(adverse events,AEs)包括2例肺炎、1例全身症状、1例结肠炎、1例肾上腺皮质功能不全、1例高血糖症和1例低钾血症。6例(14%)患者发生了治疗相关的严重不良事件,包括肺炎、急性肾损伤、低钾血症和肾上腺皮质功能不全。没有观察到治疗相关死亡病例。结论帕博利珠单抗治疗PD-L1≥1%的NScLc伴脑转移患者有效,且对所有纳入的未经治疗的脑转移患者安全。需要进一步探索免疫治疗用于NScLc合并cNS转移。

关键词：非小细胞肺癌脑转移免疫治疗帕博利珠单抗

Search for the rare decays W^(+)→D_(s)^(+)γ and Z→D^(0)γ at LHcb

在线全文

学校读者我要写书评

暂无评论

中国物理c:英文版 2023年第9期47卷 14-26页

作者： R.Aaij A.S.W.Abdelmotteleb c.Abellan Beteta F.Abudinén T.Ackernley B.Adeva M.Adinolfi P.Adlarson H.Afsharnia c.Agapopoulou c.A.Aidala Z.Ajaltouni S.Akar K.Akiba J.Albrecht F.Alessio M.Alexander A.Alfonso Albero Z.Aliouche P.Alvarez cartelle R.Amalric S.Amato J.L.Amey Y.Amhis L.An L.Anderlini M.Andersson A.Andreianov M.Andreotti D.Andreou D.Ao F.Archilli A.Artamonov M.Artuso E.Aslanides M.Atzeni B.Audurier S.Bachmann M.Bachmayer J.J.Back A.Bailly-reyre P.Baladron Rodriguez V.Balagura W.Baldini J.Baptista de Souza Leite M.Barbetti R.J.Barlow S.Barsuk W.Barter M.Bartolini F.Baryshnikov J.M.Basels G.Bassi B.Batsukh A.Battig A.Bay A.Beck M.Becker F.Bedeschi I.B.Bediaga A.Beiter V.Belavin S.Belin V.Bellee K.Belous I.Belov I.Belyaev G.Benane G.Bencivenni E.Ben-Haim A.Berezhnoy *** *** Andres D.Berninghoff H.c.Bernstein c.Bertella A.Bertolin c.Betancourt F.Betti Ia.Bezshyiko S.Bhasin J.Bhom L.Bian M.S.Bieker N.V.Biesuz S.Bifani P.Billoir A.Biolchini M.Birch F.c.R.Bishop A.Bitadze A.Bizzeti M.P.Blago T.Blake F.Blanc J.E.Blank S.Blusk D.Bobulska J.A.Boelhauve O.Boente Garcia T.Boettcher A.Boldyrev c.S.Bolognani R.Bolzonella N.Bondar F.Borgato S.Borghi M.Borsato J.T.Borsuk S.A.Bouchiba T.J.V.Bowcock A.Boyer c.Bozzi M.J.Bradley S.Braun A.Brea Rodriguez J.Brodzicka A.Brossa Gonzalo J.Brown D.Brundu A.Buonaura L.Buonincontri A.T.Burke c.Burr A.Bursche A.Butkevich J.S.Butter J.Buytaert W.Byczynski S.cadeddu H.cai R.calabrese L.calefice S.cali R.calladine M.calvi M.calvo Gomez P.campana D.H.campora Perez A.F.campoverde Quezada S.capelli L.capriotti A.carbone G.carboni R.cardinale A.cardini P.carniti L.carus A.casais Vidal R.caspary G.casse M.cattaneo G.cavallero V.cavallini S.celani J.cerasoli D.cervenkov A.J.chadwick M.G.chapman M.charles Ph.charpentier c.A.chavez Barajas M.chefdeville c.chen S.chen A.chernov S.chernyshenko V.chobanova S.cholak M.chrzaszcz A.chubykin V.chulikov P.ciambrone M.F.cicala X.cid Vidal G.ciezarek G.ciullo P.E.L.clarke M.clemencic H.V.cliff J.closier J.L.cobbledick V.coco J.A.B.coelho J.cogan E.cognera centro Brasileiro de Pesquisas Físicas(cBPF) Rio de JaneiroBrazil Universidade Federal do Rio de Janeiro(UFRJ) Rio de JaneiroBrazil center for High Energy Physics Tsinghua UniversityBeijingChina Institute Of High Energy Physics(IHEP) BeijingChina School of Physics State Key Laboratory of Nuclear Physics and Technology Peking UniversityBeijingChina University of chinese Academy of Sciences BeijingChina Institute of Particle Physics Central China Normal UniversityWuhanHubeiChina Université Savoie Mont Blanc CNRSIN2P3-LAPPAnnecyFrance Universitéclermont Auvergne CNRS/IN2P3LPCClermont-FerrandFrance Aix Marseille Univ CNRS/IN2P3CPPMMarseilleFrance UniversitéParis-Saclay CNRS/IN2P3IJCLabOrsayFrance Laboratoire Leprince-Ringuet CNRS/IN2P3Ecole PolytechniqueInstitut Polytechnique de ParisPalaiseauFrance LPNHE Sorbonne UniversitéParis Diderot Sorbonne Paris CitéCNRS/IN2P3ParisFrance I.Physikalisches Institut RWTH Aachen UniversityAachenGermany Fakultat Physik Technische Universitat DortmundDortmundGermany Max-Planck-Institut für Kernphysik(MPIK) HeidelbergGermany Physikalisches Institut Ruprecht-Karls-Universitat HeidelbergHeidelbergGermany School of Physics University College DublinDublinIreland INFN Sezione di Bari BariItaly INFN Sezione di Bologna BolognaItaly INFN Sezione di Ferrara FerraraItaly INFN Sezione di Firenze FirenzeItaly INFN Laboratori Nazionali di Frascati FrascatiItaly INFN Sezione di Genova GenovaItaly INFN Sezione di Milano MilanoItaly INFN Sezione di Milano-Bicocca MilanoItaly INFN Sezione di cagliari MonserratoItaly Universitàdegli Studi di Padova Universitàe INFNPadovaPadovaItaly INFN Sezione di Pisa PisaItaly INFN Sezione di Roma La Sapienza RomaItaly INFN Sezione di Roma Tor Vergata RomaItaly Nikhef National Institute for Subatomic Physics AmsterdamNetherlands Nikhef National Institute for Subatomic Physics and VU University Amsterdam AmsterdamNetherlands AGH-University of Science and Technology Faculty of Physics and Applied Computer Scienc

A search for the rare decays W^(+)→D_(s)^(+)γ and Z→D0γis performed using proton-proton collision data collected by the LHcb experiment at a centre-of-mass energy of 13TeV,corresponding to an integrated luminosity of 2.0fb−*** significant signal is observed for either decay mode and upper limits on their branching fractions are set using W^(+)→D_(s)^(+)γ and Z→μ+μ−decays as normalization *** upper limits are 6.5×10^(−4) and 2.1×10^(−3) at 95% confidence level for the W^(+)→D_(s)^(+)γ and Z→D^(0)γ decay modes,*** is the first reported search for the Z→D^(0)γ decay,while the upper limit on the W+→D+sγbranching fraction improves upon the previous best limit.

关键词： W/Z boson rare decay upper limit of branching fraction

从成人到儿童的结核病传播:家庭接触还是社区接触?

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

结核与肺部疾病杂志 2004年第1期7卷 1-5页

作者： H.S.Schaaf I.A.Michaelis M.richardson c.N.Booysen R.P.Gie R.Warren P.D van Helden N.Beyers 王海东 Department of Paediatrics and child Health Faculty of Health Sciences Stellenbosch University Tygerberg Tygerberg Children's Hospital Tygerberg Department of Paediatrics and child Health Faculty of Health Sciences Stellenbosch University Tygerberg Department of Medical Biochemistry Medical Research Council Centre for Molecular and Cellular Biology. Faculty of Health Sciences. Stellenbosch University Tygerberg South Africa

背景:儿童如果发生结核病,通常会假设其传染源是生活在同一家庭的成年传染性病例。本研究应用限定性片断长度多态性分析技术(RFLP)来确定从传染源到儿童的传播。设计:收集1993年到1998年诊断的成人及儿童结核病例和他们的结核分枝杆菌... 详细信息

背景:儿童如果发生结核病,通常会假设其传染源是生活在同一家庭的成年传染性病例。本研究应用限定性片断长度多态性分析技术(RFLP)来确定从传染源到儿童的传播。设计:收集1993年到1998年诊断的成人及儿童结核病例和他们的结核分枝杆菌培养物。通过访视和结核分枝杆菌菌株的RFLP分析来确定流行病学联系及证实家庭内传播。结果:1291名成人中有1139名(91％)和417名儿童中有65名(16％)籍培养结果证实为结核病。由于要重新收集痰标本和提取DNA的问题,仅对其中的832名成人和35名儿童进行了RFLP分析:19名(54％)儿童有家庭成员确诊为结核病,12名儿童有与其家庭成员相同的菌株。分离自儿童的29株(83％)菌株构成了社区簇的一部分,但与传染源有明确接触史者只有15株。结论:在具有传染性成人肺结核病例的家庭中,儿童患有结核病并不意味着必然是成人对儿童的传播。儿童可能是在社区也可能是在家庭中受到感染。此结果对在高发病率地区的接触者追踪及治疗策略有意义。

关键词：成人儿童结核病疾病传播家庭接触社区接触

评估大气细颗粒物暴露引起的全球疾病负担的一个综合风险函数

在线全文

学校读者我要写书评

暂无评论

环境与职业医学 2014年第11期31卷 898-903页

作者： Richard T.Burnett c.Arden Pope III Majid Ezzati casey Olives Stephen S.Lim Sumi Mehta Hwashin H.Shin Gitanjali Singh Bryan Hubbell Michael Brauer H.Ross Anderson Kirk R.Smith John R.Balmes Nigel G.Bruce Haidong Kan Francine Laden annette Prüss-Ustün Michelle c.Turner Susan M.Gapstur W.Ryan Diver Aaron cohen 何蓉张伊人金泰廙 Health canada OttawaOntarioCanada Brigham Young University MRc-PHE centre for Environment and Health School of Public HealthImperial College London School of Public Health University of Washington Institute for Health Metrics and Evaluation Global Alliance for clean cookstoves Harvard School of Public Health Harvard University U.S. Environmental Protection Agency Research Triangle Park School of Population and Public Health University of British ColombiaVancouverBritish ColumbiaCanada MRc-PHE centre for Environment and Health King’s College London University of california BerkeleyBerkeleyCaliforniaUSA School of Medicine University of CaliforniaSan FranciscoSan FranciscoCaliforniaUSA School of Medicine University of CaliforniaBerkeleyBerkeleyCaliforniaUSA Department of Public Health and Policy University of Liverpool School of Public Health Fudan University Exposure Epidemiologyand Risk ProgramDepartment of Environmental HealthHarvard School of Public Health World Health Organization Institute of Population Health University of OttawaOttawaOntarioCanada American cancer Society AtlantaGeorgiaUSA Health Effects Institute BostonMassachusettsUSA

[背景]评估由于环境空气中细颗粒物（PM2.5）长期暴露引起的疾病负担,需要了解相对风险度（RR）函数的图形和幅度。然而,在世界上很多观察到高PM2.5环境浓度的地方,都缺乏足够的直接证据确定死亡RR函数的图形。[目的]建立可用于全球PM2.... 详细信息

[背景]评估由于环境空气中细颗粒物（PM2.5）长期暴露引起的疾病负担,需要了解相对风险度（RR）函数的图形和幅度。然而,在世界上很多观察到高PM2.5环境浓度的地方,都缺乏足够的直接证据确定死亡RR函数的图形。[目的]建立可用于全球PM2.5暴露范围内成人死因的RR函数：缺血性心脏病（IHD）、脑血管疾病（脑卒中）、慢性阻塞性肺病（cOPD）和肺癌（Lc）。建立急性下呼吸道感染（ALRI）发病的RR函数,用于估算〈5岁的儿童中死亡率和健康生活损失年数。[方法]通过整合现有的来自于环境空气污染（AAP）、二手烟草烟雾、家用固体烹饪用燃料和主动吸烟（AS）等研究的RR信息,拟合综合暴露-反应（IER）模型。采用颗粒物质的吸入剂量,通过转化AS暴露来估计全年PM2.5的暴露当量。在估算全球环境PM2.5浓度的基础上,得出各国的人群归因分数（PAFs）。[结果]与以往负担评估中使用的其他7种模型相比,IER模型是一种优越的RR预测方法。在不同国家中,归因于AAP暴露的PAF百分数各不相同,分别为：IHD,2~41;脑卒中,1~43;cOPD,〈1~21;Lc,〈1~25;ALRI,〈1~38。[结论]我们建立了一种以细颗粒物为基础的RR模型,它通过整合来自不同类型的燃烧所产生颗粒物排放的RR信息,涵盖全球范围的暴露。当获得新的RR信息时,可以对这个模型进行更新。

关键词：细颗粒物环境空气污染风险函数全球疾病负担相对风险慢性阻塞性肺病全球环境缺血性心脏病颗粒物质烟草烟雾

Hepatitis c Virus Infection Sensitizes Human Hepatocytes to TRAIL-Induced Apoptosis in a caspase 9-Dependent Manner1

在线全文

学校读者我要写书评

暂无评论

Hepatitis C Virus Infection Sensitizes Human Hepatocytes to ...