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Analyzing the genomic and transcriptomic architecture of milk traits in Murciano-Granadina goats

Journal of Animal Science and Biotechnology 2020年第3期11卷 649-666页

作者： Dailu Guan Vincenzo Landi María Gracia Luigi-Sierra Juan Vicente Delgado Xavier Such anna castelló Betlem Cabrera Emilio Mármol-Sánchez Javier Fernández-Alvarez JoséLuis Ruiz de la Torre Casañas Amparo Martínez Jordi Jordana Marcel Amills Centre for Research in Agricultural Genomics(CRAG) CSIC-IRTA-UAB-UBUniversitat Autònoma de Barcelona08193 BellaterraSpain Departamento de Genética Universidad de Córdoba14071 CórdobaSpain Departament de Ciència Animal i dels Aliments Facultat de VeterinàriaUniversitat Autònoma de Barcelona08193 BellaterraSpain Asociación Nacional de Criadores de Caprino de Raza Murciano-Granadina(CAPRIGRAN) 18340 GranadaSpain Servei de Granges i Camps Experimentals Universitat Autònoma de Barcelona08193 BellaterraSpain

Background:In this study,we aimed to investigate the molecular basis of lactation as well as to identify the genetic factors that influence milk yield and composition in *** achieve these two goals,we have analyzed how the mRNA profile of the mammary gland changes in seven Murciano-Granadina goats at each of three different time points,i.e.78 d(T1,early lactation),216 d(T2,late lactation)and 285 d(T3,dry period)after ***,we have performed a genome-wide association study(GWAS)for seven dairy traits recorded in the 1st lactation of 822 Murciano-Granadina ***:The expression profiles of the mammary gland in the early(T1)and late(T2)lactation were quite similar(42 differentially expressed genes),while strong transcriptomic differences(more than one thousand differentially expressed genes)were observed between the lactating(T1/T2)and non-lactating(T3)mammary glands.A large number of differentially expressed genes were involved in pathways related with the biosynthesis of amino acids,cholesterol,triglycerides and steroids as well as with glycerophospholipid metabolism,adipocytokine signaling,lipid binding,regulation of ion transmembrane transport,calcium ion binding,metalloendopeptidase activity and complement and coagulation *** regard to the second goal of the study,the performance of the GWAS allowed us to detect 24 quantitative trait loci(QTLs),including three genome-wide significant associations:QTL1(chromosome 2,130.72-131.01 Mb)for lactose percentage,QTL6(chromosome 6,78.90-93.48 Mb)for protein percentage and QTL17(chromosome 17,11.20 Mb)for both protein and dry matter ***,QTL6 shows positional coincidence with the casein genes,which encode 80%of milk ***:The abrogation of lactation involves dramatic changes in the expression of genes participating in a broad array of physiological processes such as protein,lipid and carbohydrate metabolism,calcium homeostasis,cell death and tissue remo

关键词： Casein genes Dairy traits GWAS Lactation QTLs RNA-Seq

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Suitability of Blends from Virgin and Reprocessed Polylactide: Performance and Energy Valorization Kinet

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Journal of Renewable Materials 2018年第4期6卷 370-382页

作者： O.Gil-castell J.D.Badia A.Ribes-Greus Instituto de Tecnología de Materiales(ITM) Universitat Politècnica de ValènciaCamino de Vera s/n46022 ValènciaSpain Departament d’Enginyeria Química Escola Tècnica Superior d’EnginyeriaUniversitat de ValènciaAv.de la Universitat s/n46100 BurjassotSpain

A blending strategy of virgin and reprocessed polylactide may be postulated as an alternative to reduce the material cost at industrial level,and as a valorization route to plastic waste management of production *** performance of blends prepared from virgin polylactide and polylactide mechanically reprocessed up to two cycles(PLA-V/R)was assessed in terms of thermo-oxidative stability,morphology,viscoelasticity and thermal kinetics for energetic ***-V/R blends showed appropriate thermo-oxidative *** amorphous nature of polylactide was preserved after *** viscoelastic properties showed an increment of the mechanical blend effectiveness,which suggested the feasibility of using PLA-V/R blends under similar mechanical conditions to those of virgin PLA ***,it was shown that the energetic valorization of PLA-V/R blends would result in a more feasible process,due to the lower required activation energy,thus highlighting the advantages of the energetic demand for the *** conclusion,PLA-V/R blends showed similar processability,service performance and valorization routes as virgin PLA and therefore could be relevant in the sustainable circular industry of bioplastics.

关键词： Polylactide (PLA) mechanical recycling reprocessing energetic valorisation thermal analysis

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Beyond public engagement

Beyond public engagement

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作者： Ruiz-castell Pedro 等

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Spectrum of esophageal motility disorders in patients with liver cirrhosis

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World Journal of Hepatology 2020年第12期12卷 1158-1167页

作者： Mohamed Khalaf Donald castell Puja Sukhwani Elias Department of Gastroenterology and Hepatology Medical University of South CarolinaCharlestonSC 29401United States Department of Internal Medicine Medical University of South CarolinaCharlestonSC 29425United States

Disorders of esophageal motility have been described in patients with cirrhosis in a small number of *** this review,we aim to provide an overview of the available evidence on esophageal motility disorders in cirrhosis and their clinical *** review delves into the following concepts:(1)Gastroesophageal reflux disease is common in liver cirrhosis due to many mechanisms;however,when symptomatic it is usually nocturnal and has an atypical presentation;(2)Endoscopic band ligation is better than sclerotherapy in terms of its effect on esophageal motility and seems to correct dysmotilities resulting from the mechanical effect of esophageal varices;(3)Chronic alcoholism has no major effects on esophageal motility activity other than lower esophageal sphincter hypertension among those with alcoholic autonomic neuropathy;(4)An association between primary biliary cholangitis and scleroderma can be present and esophageal hypomotility is not uncommon in this scenario;and(5)Cyclosporin-based immunosuppression in liver transplant patients can have a neurotoxic effect on the esophageal myenteric plexus leading to reversible achalasia-like manifestations.

关键词： Esophagus Motility Cirrhosis Dysmotility Gastroesophageal reflux disease Manometry

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Cyclicity of the Lower Buntsandstein in the eastern part of the Central European Basin:implications for Early Triassic palaeogeography and for geochronological calibration

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Journal of Palaeogeography 2024年第2期13卷 252-292页

作者： anna Becker Polish Geological Institute-National Research Institute 4 Rakowiecka str.00-975 WarsawPoland

Lower Buntsandstein small—scale cycles recognized in the Central European Basin(CEB) are readily used for astrochronological calibration of the Early Triassic time scales,although they are not well studied *** borehole sections from the eastern part of the CEB,forming a south-north transect perpendicular to the basin axis,were studied in terms to better understand the depositional history of the Lower Buntsandstein developed as the Baltic Formation in the studied Polish part of the *** sedimentary facies were recognized,based on lithological and sedimentological investigations of 655.7 m of drill cores from the Otyń IG 1,Gorzów Wielkopolski IG 1 and Kamień Pomorski IG 1 *** facies can be grouped according to a lithological criterion into facies of predominantly siliciclastic lithology(including 9facies types) and facies of predominantly carbonate lithology(including 2 facies types).Facies analysis allowed to distinguish 8 facies associations of:1) alluvial fan,2) playa,3) sandy-muddy coastal plain,4)embayment and distal delta,5) lagoon,6) sand bars or shoals,7) ooidal shoals or bars,and 8) ***-upward(DC) and shallowing-upward(SC) sedimentary cycles were recognized in parts of the Baltic Formation,with DCs dominating in the southernmost located Otyń IG 1,and SCs dominating in Gorz ow Wielkopolski IG 1,located in the axial part of the *** cycles are very *** statistical significance of the sedimentary cycles is relatively low according to Markov-chain analysis conducted with the phpSedistat software of Stanova et al.(2009).Analysis of small—scale cycles performed on well logs of investigated boreholes and additional boreholes in the vicinity of Otyń IG 1,implementing the earlier study of Becker(2005),showed that the correlation of well-log cycles(GR cycles) and sedimentary cycles is not *** cycles can be roughly correlated with lithological carbonate—siliciclastic cycles(c-s cycles),refle

关键词： Triassic Lower Buntsandstein Cyclicity Central European Basin

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Relationship between surface area and crystal size of pure and doped cerium oxides

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Journal of Rare Earths 2010年第5期28卷 647-653页

作者： C. Bueno-Ferrer S. Parres-Esclapez D. Lozano-castelló A. Bueno-López Analytical Chemistry Nutrition & Food Sciences Department Inorganic Chemistry Department University of Alicante Ap. 99 E-03080 Alicante Spain

Pure and Zr, La or Pr-doped cerium oxides were characterised by transmission electron microscopy (TEM), N2 adsorption-desorption at –196 oC and X-ray diffraction (XRD). For crystal sizes calculation, the Scherrer and Williamson-Hall equations were compared, and the relationship between surface area and crystal size was critically discussed. It was demonstrated that the Williamson-Hall equation must be used instead of the Scherrer equation to calculate crystal sizes, since the latter equation underestimated ...

关键词： ceria XRD N2 adsorption crystal size surface area rare earths

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Cornea modelling

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Eye and Vision 2020年第1期7卷 11-25页

作者： anna Pandolfi Department of Civil and Environmental Engineering Politecnico di MilanoPiazza Leonardo da Vinci 3220133 MilanoItaly

Background:Biomechanics introduces numerous technologies to support clinical practice in ophthalmology,with the goal of improving surgical outcomes and to develop new advanced technologies with minimum impact on clinical ***,a few misconceptions on the way that computational methods should be applied to living tissues contributes to a lack of confidence towards computer-based ***:Corneal biomechanics relies on sound theories of mechanics,including concepts of equilibrium,geometrical measurements,and complex material *** peculiarities of biological tissues require the consideration of multi-physics,typical of the eye environment,and to adopt customized geometrical models constructed on the basis of advanced optical imaging and in-vivo ***:Patient-specific models are able to predict the outcomes of refractive surgery and to exploit the results of in-vivo test to characterize the material properties of the corneal ***:Corneal biomechanics can become an important support to clinical practice,provided that methods are based on the actual multi-physics and use customized geometrical and mechanical models.

关键词： Corneal biomechanics Physiologic configuration Tonometry modelling Refractive surgery modelling

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Joint power and spectrum allocation algorithm in cognitive radio networks

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Journal of Systems Engineering and Electronics 2011年第4期22卷 691-701页

作者： anna Auguste Anghuwo Communication Research Center Harbin Institute of Technology

The spectrum sharing problem between primary and cognitive users is mainly investigated. Since the interference for primary users and the total power for cognitive users are constrained, based on the well-known water-filling theorem, a novel one-user water-filling algorithm is proposed, and then the corresponding simulation results are given to analyze the feasibility and validity. After that this algorithm is used to solve the communication utility optimization problem subject to the power constraints in cognitive radio network. First, through the gain to noise ratio for cognitive users, a subcarrier and power allocation algorithm based on the optimal frequency partition is proposed for two cognitive users. Then the spectrum sharing algorithm is extended to multiuser conditions such that the greedy and parallel algorithms are proposed for spectrum sharing. Theory and simulation analysis show that the subcarrier and power allocation algorithms can not only protect the primary users but also effectively solve the spectrum and power allocation problem for cognitive users.

关键词： cognitive radio spectrum sharing water-filling algo-rithm interference constraint communication overhead.

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Plasma-assisted oxidation of benzoic acid

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Frontiers of Chemical Science and Engineering 2020年第4期14卷 513-521页

作者： anna Khlyustova Nikolay Sirotkin Laboratory of Chemistry of Hybrid Nanomaterials and Supermolecular Systems G.A.Krestov Institute of Solution Chemitry of Russian Academy of SciencesIvanovo 153045Russia

Plasma-assisted oxidation of organic com-pounds is one of the developing technologies for wastewater *** effectively accelerate degradation processes due to plasma generated reactive species and ultra-violet *** of BA in aqueous solutions by the atmospheric pressure glow discharge and underwater diaphragm discharge was studied and monitored by fluorescence and spectrophoto-metric *** type and solution pH affect the formation rates of mono-and dihydroxybenzoic *** derivatives were formed only by glow discharge *** yields of hydroxyl radical were estimated on the kinetics data for the hydroxylation of benzoic *** steps of the hydroxylation processes and further oxidation were described.

关键词： atmospheric pressure glow discharge under-water diaphragm discharge oxidation benzoic acid hydroxyl radical

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Each coin has 2 sides: a positive role of alien Potamopyrgus antipodarum (Grey, 1843) snails in reducing the infection of native lymnaeids with trematodes

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Current Zoology 2024年第2期70卷 262-269页

作者： anna Cichy anna Stanicka Elzbieta Zbikowska Faculty of Biological and Veterinary Sciences Nicolaus Copernicus University in TorunLwowska 187-100 TorunPoland

The change in the distribution of organisms in freshwater ecosystems due to natural or manmade processes raises the question of the impact of alien species on local *** most studies indicate a negative effect,the positive one is more difficult to discern,espe-cially in multispecies systems,including hosts and *** purpose of the study was to check whether the presence of an alien host,Potamopyrgus antipodarum,reduces the intensity of Echinoparyphium aconiatum metacercariae in a native host,Radix *** additionally tested the impact of water temperature and the biomass of the alien host on the dilution *** experimentally studied(1)the lifespan of echinostome cercariae in different temperatures,(2)the infectivity of cercariae toward the alien host and native host,and(3)the impact of different biomass of the alien host on the intensity of metacercariae in the native *** found that cercarial survival and infectivity were tem-perature ***,cercarial survival decreased with increasing temperature,contrary to cercarial *** cercariae entered the renal cavity of both the native host and alien host,and successfully transformed into *** number of metacercariae in the native host decreased with the increasing biomass of the alien *** results indicate that lymnaeids may benefit from the co-occur-rence with P antipodarum,as the presence of additional hosts of different origins may reduce the prevalence of parasites in native ***,the scale of the dilution effect depends not only on the increased spectrum of susceptible hosts but also on the other variables of the environment,including water temperature and host density.

关键词： biological invasion density dilution effect echinostomes Radix spp. temperature.

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