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Suggestions for Supporting a Weight Management Policy at Grocery Stores

Journal of Health Science 2016年第2期4卷 93-98页

作者： anna-maria Saarela Savonia University of Applied Sciences Kuopio FI-70201 Finland

Weight management is affected by food choice. It is important to show how challenging an environment a grocery store is from a weight management perspective. The subjects were recruited by delivering 1,000 questionnaires in November-December 2009 at the K-Citymarket Kolmisoppi, Kuopio, Finland. The subjects （n = 36, age 18-65） were recruited to represent consumers of varied experience in weight management. The subjects＇ shopping behavior was studied using verbal analysis protocol combined with wireless audio-visual observation, questionnaires and interviews in the K-Citymarket in April-May 2010. For two consecutive tasks, the subjects were given a shopping list of I 1 food categories. During the first task, they were asked to select a product they usually buy and during the second task, a product they would use for weight management. The subjects made their decisions routinely as there were none stimuli available at a supermarket in relation to weight management choices apart from versatile, abundant and small-sized labels all over food packages. The subjects had challenges while choosing food, such as the time taken （maximum 225 s） to find a suitable product among all the options of a wide product category, for example, 459 ready meals per product category with the energy variation from 30 to 330 kcal/100 g, and understanding all package labels properly, such as the GDA-label in relation to the nutrition content table. The subjects had practical suggestions, such as colored labels in shelves, how consumer-oriented marketing communication and services should be developed and provided by retailers cooperatively with health-care actors to promote consumers＇ awareness of food choices from the weight management perspective in groceries. For a consumer, it is important to be able to easily find and compare suitable products from a weight management point of view. Successful consumer marketing will achieve desirable results for manufacturers, retailers and consumers as we

关键词： Nutrition marketing consumer behavior grocery store

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Colonic sarcoidosis:Unusual onset of a systemic disease

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World Journal of Gastroenterology 2015年第11期21卷 3380-3387页

作者： Paola Erra Sonia Crusco Loredana Nugnes anna maria Pollio Gianni Di Pilla Giuseppe Biondi Giovanni Vigliardi Department of Radiology and Nuclear Medicine ASREM"F.Veneziale" Hospital Department of Pathological Anatomy and Histology:Cytodiagnostics ASREM"F.Veneziale" Hospital Department of General Surgery ASREM"F.Veneziale" Hospital

Sarcoidosis is a multisystem chronic inflammatory condition of unknown etiology that has the potential to involve every tissue in the *** in the gastrointestinal system,and particularly the colon,is very ***,we report the case of a 57-yearold man with no previous diagnosis of sarcoidosis who presented with new onset of abdominal pain and constipation.A colonoscopy revealed that the abdominal pain was caused by an obstructing lesion in the cecum-ascending colon and lacked a clear histologic *** investigation revealed concentric wall thickening of the cecum-ascending colon with multiple satellite lymphadenopathies,highly suggestive of a *** patient underwent a laparotomy and a right hemicolectomy was performed.A diagnosis of colonic sarcoidosis was made after the resected specimen was ***,a chest computed tomography scan revealed lung involvement with atypical radiologic features in the absence of respiratory *** histologic examination of the surgical specimen can yield a diagnosis of gastrointestinal sarcoidosis due to the non-specificity of endoscopic and radiologic findings.

关键词： Colon Sarcoidosis Hemicolectomy Systemic disease N

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A fully inkjet-printed disposable glucose sensor on paper

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npj Flexible Electronics 2018年第1期2卷 263-270页

作者： Eloïse Bihar Shofarul Wustoni anna maria Pappa Khaled N.Salama Derya Baran Sahika Inal Division of Biological and Environmental Science and Engineering King Abdullah University of Science and Technology(KAUST)Thuwal 23955Saudi Arabia Division of Physical Science and Engineering KAUST Solar CenterKAUSTThuwal 23955Saudi Arabia Department of Chemical Engineering and Biotechnology University of CambridgePhilippa Fawcett DriveCambridge CB30ASUK Division of Computer Electrical and Mathematical Sciences and EngineeringAdvanced Membranes and Porous Materials CenterKAUSTThuwal 23955Saudi Arabia

Inexpensive and easy-to-use diagnostic tools for fast health screening are imperative,especially in the developing world,where portability and affordability are a *** monitoring of metabolite levels can provide useful information regarding key metabolic activities of the body and detect the concomitant irregularities such as in the case of diabetes,a worldwide chronic ***,the majority of daily glucose monitoring tools rely on piercing the skin to draw *** pain and discomfort associated with finger pricking have created a global need to develop non-invasive,portable glucose *** this work,we develop a disposable analytical device which can measure physiologically relevant glucose concentrations in human saliva based on enzymatic electrochemical *** use inkjet-printing technology for the rapid and low-cost deposition of all the components of this glucose sensor,from the electronics to the biorecognition elements,on commercially available paper *** only electronic component of the sensor is the conducting polymer poly(3,4 ethylenedioxythiophene)doped with polystyrene sulfonate(PEDOT:PSS),while the biorecognition element comprises of the enzyme glucose oxidase coupled with an electron *** demonstrate that one month after its fabrication and storage in air-free environment,the sensor maintains its function with only minor performance *** fully printed,all-polymer biosensor with its ease of fabrication,accuracy,sensitivity and compatibility with easy-to-obtain biofluids such as saliva aids in the development of next generation low-cost,noninvasive,eco-friendly,and disposable diagnostic tools.

关键词： maintain sensor printing

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Plasma-assisted oxidation of benzoic acid

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Frontiers of Chemical Science and Engineering 2020年第4期14卷 513-521页

作者： anna Khlyustova Nikolay Sirotkin Laboratory of Chemistry of Hybrid Nanomaterials and Supermolecular Systems G.A.Krestov Institute of Solution Chemitry of Russian Academy of SciencesIvanovo 153045Russia

Plasma-assisted oxidation of organic com-pounds is one of the developing technologies for wastewater *** effectively accelerate degradation processes due to plasma generated reactive species and ultra-violet *** of BA in aqueous solutions by the atmospheric pressure glow discharge and underwater diaphragm discharge was studied and monitored by fluorescence and spectrophoto-metric *** type and solution pH affect the formation rates of mono-and dihydroxybenzoic *** derivatives were formed only by glow discharge *** yields of hydroxyl radical were estimated on the kinetics data for the hydroxylation of benzoic *** steps of the hydroxylation processes and further oxidation were described.

关键词： atmospheric pressure glow discharge under-water diaphragm discharge oxidation benzoic acid hydroxyl radical

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Each coin has 2 sides: a positive role of alien Potamopyrgus antipodarum (Grey, 1843) snails in reducing the infection of native lymnaeids with trematodes

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Current Zoology 2024年第2期70卷 262-269页

作者： anna Cichy anna Stanicka Elzbieta Zbikowska Faculty of Biological and Veterinary Sciences Nicolaus Copernicus University in TorunLwowska 187-100 TorunPoland

The change in the distribution of organisms in freshwater ecosystems due to natural or manmade processes raises the question of the impact of alien species on local *** most studies indicate a negative effect,the positive one is more difficult to discern,espe-cially in multispecies systems,including hosts and *** purpose of the study was to check whether the presence of an alien host,Potamopyrgus antipodarum,reduces the intensity of Echinoparyphium aconiatum metacercariae in a native host,Radix *** additionally tested the impact of water temperature and the biomass of the alien host on the dilution *** experimentally studied(1)the lifespan of echinostome cercariae in different temperatures,(2)the infectivity of cercariae toward the alien host and native host,and(3)the impact of different biomass of the alien host on the intensity of metacercariae in the native *** found that cercarial survival and infectivity were tem-perature ***,cercarial survival decreased with increasing temperature,contrary to cercarial *** cercariae entered the renal cavity of both the native host and alien host,and successfully transformed into *** number of metacercariae in the native host decreased with the increasing biomass of the alien *** results indicate that lymnaeids may benefit from the co-occur-rence with P antipodarum,as the presence of additional hosts of different origins may reduce the prevalence of parasites in native ***,the scale of the dilution effect depends not only on the increased spectrum of susceptible hosts but also on the other variables of the environment,including water temperature and host density.

关键词： biological invasion density dilution effect echinostomes Radix spp. temperature.

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Regulation of Meristem Size by Cytokinin Signaling

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Journal of Integrative Plant Biology 2011年第6期53卷 446-454页

作者： anna Skylar Molecular and Computational Biology University of Southern CaliforniaLos AngelesCA

The plant meristems possess unique features that involve maintaining the stem cell populations while providing cells for continued development. Although both the primary shoot apical meristem （SAM） and the root apical meristem （RAM） are specified during embryogenesis, post-embryonic tissue proliferation is required for their full establishment and maintenance throughout a plants＇ life. The phytohormone cytokinin （CK） interacts with other systemic signals and is a key regulator of meristem size and functions. The SAM and the RAM respond to CK stimulations in different manners： CK promotes tissue proliferation in the SAM through pathways dominated by homeobox transcription factors, including the class I KNOX genes, ST^P, and WUS; and curiously, it favors proliferation at low levels and differentiation at a slightly higher concentration in the RAM instead. Here we review the current understanding of the molecular mechanisms underlying CK actions in regulating meristematic tissue proliferation.

关键词： cytokinin signaling meristem tissue proliferation.

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Carcinosarcoma of the breast:Facing the challenge of a rare nosologic entity

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World Journal of Clinical Cases 2025年第2期13卷 14-20页

作者： Aikaterini Mastoraki maria Tsamopoulou Foivos-Konstantinos Stamatis Alexios Strimpakos Ero Mouchtouri Christiana Panagi Evgenia Mela Sotiria Mastoraki Aristotelis Kechagias Dimitrios Schizas Department of Surgery National and Kapodistrian University of AthensLaikon General HospitalAthens 11527Greece Department of Surgery National and Kapodistrian University of AthensAthens 11527Greece Department of Medical Oncology Hygeia HospitalAthens 15123Greece Department of Radiology Henry Dunant Hospital CenterAthens 11526Greece Department of Surgery Athens Metropolitan HospitalAthens 15562Greece

Carcinosarcoma(CS),also known as metaplastic breast carcinoma with mesenchymal differentiation,is one of the five distinct subtypes of metaplastic breast *** is considered as a mixed,biphasic neoplasm consisting of a carcinomatous component combined with a malignant nonepithelial element of mesenchymal origin without an intermediate transition *** cellular origin of this neoplasm remains controversial,most researchers declare that neoplastic cells derive from a cellular structure with potential biphasic *** recent research on the therapeutic strategies against CS neoplastic disorders,surgical resection appears the only potentially curative *** CS metastasize by the lymphatic route,axillary assessment with sentinel lymph node biopsy and/or axillary lymph node dissection is always ***,the tumor also presents a hematogenous metastatic pattern including pleural,pulmonary,liver,brain and less commonly bone ***,surgical removal of breast CS does not necessarily ensure patient’s long-term ***,alternative therapies,such as radio-and chemotherapy proved insufficient and 5-year survival rate is ***,there is evidence that following surgery,the combination of radio and chemotherapy is associated with a better prognosis than either treatment *** aim of this review is to evaluate the results of surgical treatment for breast CS with special reference to the extent of its histological *** features,histogenesis,morphological and immunochemical findings are discussed,while the role of current diagnostic and therapeutic management of this aggressive neoplasm is emphasized.

关键词： Carcinosarcoma Breast Diagnostic approach Therapeutic management Prognostic parameters

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Learning from Evolution： Thellungiella Generates New Knowledge on Essential and Critical Components of Abiotic Stress Tolerance in Plants

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Molecular Plant 2009年第1期2卷 3-12页

作者： anna Amtmann Plant Science Group FBLS University of Glasgow Glasgow G12 8QQ UK

Thellungiella salsuginea （halophila） is a close relative of Arabidopsis thaliana but, unlike A. thaliana, it grows well in extreme conditions of cold, salt, and drought as well as nitrogen limitation. Over the last decade, many laboratories have started to use Thellungiella to investigate the physiological, metabolic, and molecular mechanisms of abiotic stress tolerance in plants, and new knowledge has been gained in particular with respect to ion transport and gene expression. The advantage of Thellungiella over other extremophile model plants is that it can be directly compared with Arabidopsis, and therefore generate information on both essential and critical components of stress tolerance. Thellungiella research is supported by a growing body of technical resources comprising physiological and molecular protocols, ecotype collections, expressed sequence tags, cDNA-libraries, microarrays, and a pending genome sequence. This review summarizes the current state of knowledge on Thellungiella and re-evaluates its usefulness as a model for research into plant stress tolerance.

关键词： abiotic/environmental stress ion channels adaptation - evolutionary comparative genomics gene expres-sion Brassica.

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Oleuropein-Specific-β-Glucosidase Activity Marks the Early Response of Olive Fruits (Olea europaea) to Mimed Insect Attack

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Agricultural Sciences in China 2008年第6期7卷 703-712页

作者： Antonia Spadafora Silvia Mazzuca Francesca Fiorella Chiappetta Attilio Parise Enzo Perri anna maria Innocenti Laboratorio di Citofisiologia Vegetale Dipartimento di Ecologia Cubo 6b Ponte Bucci Università della Calabria 87030 Rende (CS) Italy C.R.A. Centro di Ricerca per l'Olivicoltura e l'Industria Olearia Contrada Li Rocchi 87030 Rende Italy

Olive fruits are seriously deteriorated by pre and postharvest damage due to the attack of insects, such as Bactrocera olaea, which strongly alters the quality of olives. Defence response in olive fruits injured both by pathogens and by mechanical damages has been associated with the enzyme β-glucosidase, which specifically hydrolyses oleuropein, producing highly reactive aldehyde molecules. In situ detection of ^-glucosidase activity in olive fruit tissues following injury, which simulates Bactrocera oleae punctures, is reported. The assay was performed in two cultivars showing different degrees of susceptibilities to fly infestation. In both cultivars, the histochemical assay for β-glucosidase showed that within 20 min after the injury, a strong ^-glucosidase activity could be observed in the damaged tissues. Thereafter a progressive enzyme inactivation occurred starting from tissues around the boundary of the injury with decrease of the enzyme activity and stopped after 3 h. Whereas the mass of active cells reached a distance of （300±50） μm from the edge of the injury. Biochemical analyses showed that in extracts of the injured fruit, β-glucosidase activity rapidly increased within 20 min from injury, thereafter decreasing and reaching values comparable with those in intact fruits. Following puncture, the oleuropein contents did not change significantly in the high susceptibility cultivar, whereas it rapidly decreased in the cultivar showing low susceptibility. The results strongly suggest that olive fruits susceptible towards fly infestation could be related to the ability of the oleuropein-degrading-β-glucosidase to produce the highly reactive molecules in the damaged tissues. As a consequence of puncture, high level of peroxidase activity was detected. This feature also suggested that this enzyme could play a key role in the defence response against insect injuries.

关键词： β-glucosidase (EC 3.2.1.21) oleuropein Olea europaea Bactrocera oleae infestation cultivar resistance

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家族性高胆固醇血症国内外诊疗异同

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中国全科医学 2025年第6期28卷 655-665页

作者：马弘阳岳岸娜孙康云南京医科大学附属苏州市立医院心血管内科江苏省苏州市215000

家族性高胆固醇血症(FH)是一种常见的遗传代谢性疾病,主要特征是低密度脂蛋白胆固醇(LDL-C)异常升高,可表现为角膜弓、黄色瘤等症状。长期高水平的LDL-C会增加动脉粥样硬化性心血管疾病(ASCVD)的风险。FH患者早发ASCVD的风险较高,纯合型... 详细信息

家族性高胆固醇血症(FH)是一种常见的遗传代谢性疾病,主要特征是低密度脂蛋白胆固醇(LDL-C)异常升高,可表现为角膜弓、黄色瘤等症状。长期高水平的LDL-C会增加动脉粥样硬化性心血管疾病(ASCVD)的风险。FH患者早发ASCVD的风险较高,纯合型的FH病情更为严重。全球FH的流行率逐渐受到重视,但诊断和治疗仍存在不足。借着《2023年中国血脂管理指南》的发布,本文主要比较了国内外关于FH筛查、诊断的不同,用于强调筛查血脂情况的重要性,并建议早期识别FH患者。同时,基因检测也被推荐,不仅限于少数基因,还应包含其他相关基因或全基因组检测。此外,本文也比较了不同指南对于FH患者LDL-C控制管理水平的差异,以及对于不同LDL-C划分的ASCVD危险因素新要素;比较了不同指南在饮食、生活方式、药物控制等方面的差别,指出国内外一致认为他汀类药物是主要的降脂药物,联合应用尤为重要,但对于最大剂量后LDL-C控制未达标的患者国际血脂护理指南有一定更新。同时,对于纯合型FH(HoFH)患者,高强度他汀类药物联合其他药物治疗是首选,早期的治疗更为关键,适当提早脂蛋白单采术与前蛋白转换酶枯草溶菌素9(PCSK9)抑制剂的应用有助于降低ASCVD的发病率和死亡率。

关键词：高胆固醇血症分子基础诊断诊疗方案指南差异

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