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Screening of Type 2 Diabetes in the City of Belo Horizonte: Differences between Genders

Open Journal of Endocrine and Metabolic Diseases 2016年第4期6卷 141-149页

作者： Braulio Roberto Gonçalves Marinho Couto Katiussia Brito Porto Fabiane de Freitas Sales deborah Campos oliveira Larissa da Silva Pacheco Lídia christina Guimarães Pereira Talita Santos de Almeida Geiza Francielle Rodrigues de Souza Mariana Santos Romualdo Jaqueline Paulino de Souza Clara Araújo Veloso Instituto de Ciências Biológicas e da Saúde (ICBS) Centro Universitário de Belo Horizonte Brasil

Introduction: Diabetes mellitus is a major public health problem that carries a high social and economic burden. Its diagnosis is unknown in half of individuals who have the disease. The diagnosis of the risk factors should be done in the beginning, since changes in lifestyle and hyperglycemic correction may delay the appearance of the disease and its complications. In this context, screening has been considered an important tool for an early detection of diabetes in asymptomatic adults. Objective: The objective is to track diabetes in people from BH, comparing genders. Patients and methods: People were interviewed with questions concerning the risk factors associated with the development of diabetes. According to the risk factors present, they were classified as non-diabetic [ND], pre-diabetic [PD] or diabetic [DM]. Statistical analyses were performed considering p ≤ 0.05 as significant. Results: 1264 individuals participated (5.5% DM, 6.5% PD, 88.0% ND). When grouped, PD and DM males were more prevalent than PD and DM females. Those in the DM group had higher blood pressure, age, glycaemia, number of past smokers, first-degree relatives with diabetes than either PD or ND. Both males and females in DM and PD groups had a higher waist circumference than did either ND males or females. ND men had a higher intake of fried food and smoked more in the past than ND women. Both ND and PD males had higher blood pressure than women from the same groups. Conclusion: Screening for diabetes is very important for an early diagnosis and to avoid future complications in patients. It’s possible to infer that women are more conscientious when it comes to taking care of themselves than men.

关键词： Diabetes Mellitus Screening Gender Risk Factors

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Urinary Incontinence in Pregnant Women: Integrative Review

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Open Journal of Nursing 2016年第3期6卷 229-238页

作者： Eveliny Silva Martins Ana Karina Bezerra Pinheiro Priscila de Souza Aquino Mônica oliveira Batista Oriá Régia christina Moura Barbosa Castro Diego Jorge Maia Lima Karízia Vilanova Andrade Carla Suellen Pires de Sousa Sâmia Monteiro Holanda department of Nursing Federal University of Ceará Fortaleza Brazil department of Nursing State University of Ceará Fortaleza Brazil

Objective: To characterize the scientific production related to the impact of urinary incontinence on quality of life of pregnant women. Method: An integrative review carried out from September 2014 to May 2015. The search was conducted in six databases, and a final sample of seventeen publications was presented. The data were presented in tables. Results: Incontinence related factors are: Being older, second pregnancy, multiparity, constipation, smoking, and obesity. Stress incontinence is the most occurring in pregnant women, causing an adverse impact on quality of life. Discussion: It is for health professionals who try to create effective coping strategies for minimizing consequences generated by the accidental loss of urine. Conclusion: Urinary incontinence affects the mother’s life, resulting in social, behavioral, physical and emotional harm, taking this woman to be excluded from society and feel insecure about their health.

关键词： Urinary Incontinence Quality of Life Pregnant Women

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VLO5,A HETERODIMERIC UGAND OF alpha9/alpha4betal INTEGRIN INHIBITS NEUTROPHILAPOPTOSIS:INVOLVEMENT OF Bcl-2 FAMILY

VLO5,A HETERODIMERIC UGAND OF alpha9/alpha4betal INTEGRIN IN...

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第十五届国际药理学大会

作者： Saldanha-Gama Roberta Moraes Joao Mariano-oliveira Andrea deFreitas Marta Zingali Russolina MarcinKiewicz Cezary Barja-Fidalgo christina dept.Pharmacology-IBRAG-UERJ dept.Pharmacology-IBRAG-UERJ dept.Pharmacology-IBRAG-UERJ dept.Pharmacology-IBRAG-UERJ IBqM-UFRJ dept.Biology-Temple University dept.Pharmacology-IBRAG-UERJ

＜正＞ In this study we evaluated the effect of VLO5 on human neutrophil apoptosis and the involvement of integrincoupled signaling pathways in this process. VLO5 potently inhibited spontaneous apoptosis apparently through interaction with alpha9betal integrin and activation of Erk-2 and PI3K pathways as VLO5 induced Erk2 nuclear translocation. FAK-PI3K association, and LY294002. a PI3K inhibitor, and PD95059. an Erk2 inhibitor, reverted VLO5 effects. Accordingly VLO5 induced Bcl-xL expression and Bad degradation. Moreover VLO5 modulates Bax mitochodrial insertion and prevents cytochrome c release. These data suggest that interaction of VLO5 with alpha9betal integrin on human neutrophils might be related with its anti-apoptotic effect, which is dependent on PI3K and Erk2 activation.

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