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Dynamical study of a predator-prey system with Michaelis-Menten type predator-harvesting

生物数学学报:英文版 2023年第8期16卷 121-153页

作者： ankur jyoti kashyap Quanxin Zhu Hemanta Kumar Sarmah Debasish Bhattacharjee Department of Mathematics Gauhati University AssamIndia Department of Mathematics Assam Royal Global University GuwahatiIndia School of Mathematical Sciences and Statistics Hunan Normal University Changsha410081P.R.China Sajkashyap.maths@***

The predation process plays a significant role in advancing life evolution and the maintenance of ecological balance and *** cooperation in predators is one of the most remarkable features of the predation process,which benefits the predators by developing fear upon their *** study investigates the dynamical behavior of a modified LV-type predator-prey system with Michaelis-Menten-type harvesting of predators where predators adopt cooperation strategy during *** ecologically feasible steady states of the system and their asymptotic stabilities are *** local codimension one bifurcations,***,saddle-node and Hopf bifurcations,that emerge in the system are *** approach is utilized to show the appearance of transcritical bifurcation and saddle-node bifurcation.A backward Hopfbifurcation is detected when the harvesting effort is increased,which destabilizes the system by generating periodic *** stability nature of the Hopf-bifurcating periodic orbits is determined by computing the first Lyapunov *** analyses revealed that above a threshold value of the harvesting effort promotes the coexistence of both *** periodic solutions of the system are also observed when the conversion efficiency rate or the hunting cooperation rate is *** have also explored codimension two bifurcations *** generalized Hopf and the Bogdanov-Takens bifurcation exhibit by the *** visualize the dynamical behavior of the system,numerical simulations are conducted using an ecologically plausible parameter *** existence of the bionomic equilibrium of the model is ***,an optimal harvesting policy for the proposed model is derived by considering harvesting effort as a control parameter with the help of Pontryagins maximum principle.

关键词： Hunting cooperation Michaelis-Menten-type harvesting transcritical and saddle-node bifurcation Hopf bifurcation optimal harvesting policy

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Bioinspired nanomaterials for wearable sensing and human–machine interfacing

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Nano Research 2024年第2期17卷 445-461页

作者： Vishesh kashyap Junyi Yin Xiao Xiao Jun Chen Department of Bioengineering University of CaliforniaLos AngelesLos AngelesCA 90095USA Department of Mechanical and Aerospace Engineering University of CaliforniaLos AngelesLos AngelesCA 90095USA

The inculcation of bioinspiration in sensing and human–machine interface(HMI)technologies can lead to distinctive characteristics such as conformability,low power consumption,high sensitivity,and unique properties like self-healing,self-cleaning,and *** sensing and HMI are fields rife with opportunities for the application of bioinspired nanomaterials,particularly when it comes to wearable sensory systems where biocompatibility is an additional *** review discusses recent development in bioinspired nanomaterials for wearable sensing and HMIs,with a specific focus on state-of-the-art bioinspired capacitive sensors,piezoresistive sensors,piezoelectric sensors,triboelectric sensors,magnetoelastic sensors,and electrochemical *** also present a comprehensive overview of the challenges that have hindered the scientific advancement in academia and commercialization in the industry.

关键词： bioinspired nanomaterials human–machine interface wearable sensors wearable bioelectronics

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Early antiplatelet therapy used for acute ischemic stroke and intracranial hemorrhage

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World Journal of Clinical Cases 2024年第4期12卷 677-680页

作者： Venkata Buddhavarapu Rahul kashyap Salim Surani Department of Medicine Banner Baywood Medical CenterMesaAZ 85206United States Department of Research Wellspan HealthYorkPA 17403United States Department of Medicine&Pharmacology Texas A&M UniversityCollege StationTX 77843United States

In this editorial we comment on the article published by Zhang et al in the recent issue of World Journal of Clinical *** evaluate their claims on the benefit of use of Aspirin in the early management of patients with ischemic *** also comment on their contention of using aspirin in the early management of patients with intracranial hemorrhage,a practice not seen in modern *** clinical trials such as the International Stroke Trial and the Chinese Acute Stroke Trial have shown the benefit of Aspirin use within 48 h of patients with Acute Ischemic *** findings were corroborated in the open-label trial performed by Zhang et al in a smaller sample group of 25 patients where they showed improvement in functional scores at 90 days without an increase in adverse *** such,this intervention is also recommended by the American Heart Association stroke guidelines from *** regard to Intracranial hemorrhage,traditional practice has been to discontinue or avoid antiplatelet therapy in these patient ***,no studies have been done to evaluate this management strategy that is more borne out of the mechanism behind Aspirin’s effect on the coagulation *** et al evaluate the benefits of Aspirin on patients with low-volume intracranial hemorrhage,i.e.,less than 30 mL on computed tomo-graphy imaging,and show no increase in *** caveat of this finding is that all outcomes were pooled into one group for results,and the number of patients was *** more studies with larger patient groups are required,the data from Zhang et al suggests that patients with small-volume intracranial hemorrhages may benefit from Aspirin administration in the acute phase of management.

关键词： Aspirin Ischemic stroke Intracranial hemorrhage CVA Antiplatelet therapy

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Dupuytren’s disease:A review

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Chinese Journal of Plastic and Reconstructive Surgery 2024年第3期6卷 142-148页

作者： Malay Sarkar Nitin kashyap Irappa Madabhavi Department of Pulmonary Medicine Indira Gandhi Medical CollegeShimla 171001Himachal PradeshIndia Department of Plastic and Reconstructive Surgery Atal Institute of Medical SuperspecialitiesShimla 171001Himachal PradeshIndia Department of Medical and Pediatric Oncology and Hematology Jawaharlal Nehru Medical CollegeKLE Academy of Higher Education and ResearchBelagaviKarnataka 590010India

Dupuytren’s disease is a well-known benign fibroproliferative disorder that affects the palmar and digital fasciae of the *** spectrum includes nodule formation,cord formation,and flexion contracture of the digits,which may result in functional *** deformities are often progressive and *** is a cornerstone *** review discusses the epidemiology,pathophysiology,risk factors,clinical manifestations,and management of Dupuytren’s disease.

关键词： Dupuytren’s contracture Dupuytren’s disease Palmar aponeurosis Fasciectomy

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Safety of teplizumab in patients with high-risk for diabetes mellitus type 1:A systematic review

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World Journal of Diabetes 2024年第8期15卷 1793-1801页

作者： Venkata Buddhavarapu Gagandeep Dhillon Harpreet Grewal Pranjal Sharma Rahul kashyap Salim Surani Department of Medicine Banner Baywood Medical CenterBanner HealthMesaAZ 85206United States Department of Medicine UM Baltimore Washington Medical CenterGlen BurnieMD 21061United States Department of Radiology Ascension Sacred Heart HospitalPensacolaFL 32504United States Department of Medicine Northeast Ohio Medical CenterRootstownOH 44272United States Department of Research Wellspan HealthYorkPA 17403United States Anesthesiology Mayo ClinicRochesterMN 55905United States Department of Medicine&Pharmacology Texas A&M UniversityCollege StationTX 77843United States

BACKGROUND The incidence of diabetes mellitus type 1(DM1)has been rising worldwide because of improvements in diagnostic techniques and improved access to care in countries with lower socioeconomic status.A new anti-CD4 antibody,Teplizumab,has been shown to delay the progression of DM1 and is the only medication approved for this ***,more information is needed about the safety profile of this *** To identify the odds ratios(OR)of systems-based adverse effects for Teplizumab when compared to *** An extensive systematic review was conducted from the inception of the medication until December 31,*** clinical trials and studies that evaluated Teplizumab vs placebo were included in the initial *** study protocol was designed using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines guidelines and was registered in PROSPERO(ID:CRD42024496169).Crude OR were generated using RevMan Software version *** After screening and review,5 studies were selected to determine the risk of adverse effects of teplizumab compared to placebo.A total of 561 patients were included in the study *** adverse effects and system-based adverse effects were studied and *** determined that patients receiving Teplizumab had a higher risk of developing gastrointestinal(GI)(OR=1.60,95%CI:1.01-2.52,P=0.04),dermatological(OR=6.33,95%CI:4.05-9.88,P<0.00001)and hematological adverse effects(OR=19.03,95%CI:11.09-32.66,P<0.00001).These patients were also significantly likely to have active Epstein-Barr Virus infection(OR=3.16,95%CI:1.51-6.64,P<0.002).While our data showed that patients receiving Teplizumab did have a higher incidence of total adverse effects vs placebo,this finding did not reach statistical significance(OR=2.25,95%CI:0.80-6.29,P=0.12).CONCLUSION Our systematic review suggests that Teplizumab patients are at risk for significant adverse effects,primarily related to GI,dermatological,and hematolog

关键词： Teplizumab Diabetes mellitus type 1 Adverse effects Monoclonal antibody Systematic review

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Helicobacter pylori isolated from gastric juice have higher pathogenic potential than biopsy isolates

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Genes & Diseases 2024年第1期11卷 34-37页

作者： Budhadev Baral Dharmendra kashyap Nidhi Varshney Tarun Prakash Verma Ajay Kumar Jain Debi Chatterji Vinod Kumar Amit Mishra Awanish Kumar Hem Chandra Jha Infection Bioengineering Group Department of Biosciences and Biomedical EngineeringIndian Institute of Technology IndoreSimrolIndoreMadhya Pradesh 453552India Choithram Hospital and Research Center IndoreMadhya Pradesh452014India Department of Metallurgy Engineering and Materials Science Indian Institute of Technology IndoreSimrolIndoreMadhya Pradesh 453552India Department of Bioscience&Bioengineering Indian Institute of Technology JodhpurNH 65 Nagaur RoadJodhpur DistrictKarwarRajasthan 342037India Department of Biotechnology National Institute of Technology RaipurGE RoadRaipurChhattisgarh 492010India

Persistent gastritis induced by Helicobacter pylori(***)is the strongest known risk factor for gastric cancer(GC).*** is prevalent in about 50%world's population,while it causes cancer in less than 2%of exposed individuals.1 Our studies found that *** infection can induce oncogenic properties in AGS cells by deregulating multiple factors associated with the cell cycle,apoptosis,and other important events associated with cancer progression.

关键词： H.pylori pylori Helicobacter

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Dupuytren's disease: A review

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Chinese Journal of Plastic and Reconstructive Surgery 2024年第3期 142-148页

作者： Malay Sarkar Nitin kashyap Irappa Madabhavi Department of Pulmonary Medicine Indira Gandhi Medical College Department of Plastic and Reconstructive Surgery Atal Institute of Medical Superspecialities Department of Medical and Pediatric Oncology and Hematology Jawaharlal Nehru Medical College KLE Academy of Higher Education and Research

Dupuytren's disease is a well-known benign fibroproliferative disorder that affects the palmar and digital fasciae of the hands. This spectrum includes nodule formation, cord formation, and flexion contracture of the digits,which may result in functional limitations. These deformities are often progressive and irreversible. Surgery is a cornerstone therapy. This review discusses the epidemiology, pathophysiology, risk factors, clinical manifestations, and management of Dupuytren's disease.

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User Perspective of Misplaced PPIUCD and Factors Resulting in PPIUCD Removal: Qualitative Pilot Study

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Open Journal of Epidemiology 2024年第3期14卷 517-532页

作者： A. G. Radhika Rashmi Gupta Pooja kashyap Ravleen Bakshi Department of Obstetrics and Gynecology University College of Medical Sciences & Guru Teg Bahadur Hospital Dilshad Garden Delhi India GTB Hospital Delhi India Indian Council of Medical Research Delhi India

Objective: The aim of the current study was to assess the impact of operative interventions for misplaced device among women who opted for PPIIUCD and the evaluation of reasons for PPIUCD removal within the follow up period of two years. Design: A descriptive exploratory study was conducted over three months among fourteen PPIUCD acceptors at a tertiary care health facility in Delhi, India. Face-to-face & telephonic in-depth interviews were conducted with a selected sample of PPIUCD acceptors who had later opted for its removal. Results: Participants (n = 14) aged 24 – 40 exhibited generally positive attitudes towards PPIUCDs indicating an indicate an understanding of the importance of PPIUCD in preventing unintended pregnancies. Menstrual disturbance and misplaced IUCD were major reasons for removal. despite their own experience necessitating the removal of IUCD, positive experience by other family members (mothers in law) in this study helped to keep the confidence on the contraceptive. Themes included (a) general experience of PPIUCD use (b) Health Facility accessed for removal of IUCD (c) Would she recommend it to others? (d) preferred contraceptive after removal of IUCD. Conclusion: Misplaced IUCD, missing thread, menstrual irregularities, and pain are all associated with PPIUCD and are important reasons for dissatisfaction. Appropriate, timely and supportive individualized care that address knowledge gaps, societal perceptions, and healthcare system challenges would certainly help in reducing dissatisfaction due to PPIUCD and thereby the removal rates.

关键词： Postpartum Intrauterine Device PPIUCD LARC Long Acting Reversible Contraception Postpartum Family Planning Contraception

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21st century critical care medicine:An overview

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World Journal of Critical Care Medicine 2024年第1期13卷 1-14页

作者： Smitesh Padte Vikramaditya Samala Venkata Priyal Mehta Sawsan Tawfeeq Rahul kashyap Salim Surani Department of Research Global Remote Research Scholars ProgramSt.PaulMN 55104United States Department of Hospital Medicine Cheshire Medical Center/Dartmouth HealthKeeneNH 03431United States Department of Research WellSpan HealthYorkPA 17403United States Department of Pulmonary&Critical Care Medicine Mayo ClinicRochesterMN 55905United States Department of Medicine&Pharmacology Texas A&M UniversityCollege StationTX 77843United States

Critical care medicine in the 21st century has witnessed remarkable advancements that have significantly improved patient outcomes in intensive care units(ICUs).This abstract provides a concise summary of the latest developments in critical care,highlighting key areas of *** advancements in critical care include Precision Medicine:Tailoring treatments based on individual patient characteristics,genomics,and biomarkers to enhance the effectiveness of *** objective is to describe the recent advancements in Critical Care ***:The integration of telehealth technologies for remote patient monitoring and consultation,facilitating timely *** intelligence(AI):AI-driven tools for early disease detection,predictive analytics,and treatment optimization,enhancing clinical *** Support:Advanced life support systems,such as Extracorporeal Membrane Oxygenation and Continuous Renal Replacement Therapy provide better organ *** Control:Innovative infection control measures to combat emerging pathogens and reduce healthcare-associated *** Strategies:Precision ventilation modes and lung-protective strategies to minimize ventilatorinduced lung *** Management:Early recognition and aggressive management of sepsis with tailored ***-Centered Care:A shift towards patient-centered care focusing on psychological and emotional wellbeing in addition to medical *** conducted a thorough literature search on PubMed,EMBASE,and Scopus using our tailored strategy,incorporating keywords such as critical care,telemedicine,and sepsis management.A total of 125 articles meeting our criteria were included for qualitative *** ensure reliability,we focused only on articles published in the English language within the last two decades,excluding animal studies,in vitro/molecular studies,and non-original data like editorials,letters,protocols,and conference abs

关键词： Critical care medicine Intensive care unit Precision medicine Telemedicine Artificial intelligence Organ support Sepsis Infection control Patient-centered care

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Measuring turbulence in a circulating fluidized bed using PIV techniques

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Particuology 2011年第6期9卷 572-588页

作者： Mayank kashyap Benjapon Chalermsinsuwan Dimitri Gidaspow Department of Chemical and Biological Engineering Illinois Institute of Technology Fuel Research Center Department of Chemical Technology Faculty of Science Chulalongkorn University Center of Excellence for Petroleum Petrochemicals and Advanced Materials Chulalongkorn University

This study utilized the particle image velocimetry （P1V） technique, non-invasively near the wall, in the developing region, for the measurements of laminar and turbulent properties during circulation of Geldart B type particles in the U.S. Department of Energy （DOE） National Energy Technology Laboratory （NETL） riser. A novel method was used to measure axial and radial laminar and turbulent solids dispersion coefficients using autocorrelation technique. The instantaneous and hydrodynamic velocities for the solid phase were measured simultaneously in the axial and radial directions using a CCD camera, with the help of a colored rotating transparency. The measured properties, such as laminar and Reynolds stresses, laminar and turbulent granular tempera- tures, laminar and turbulent dispersion coefficients and energy spectra exhibited anisotropy. The mixing in the riser was on the level of clusters. The total granular temperatures were in reasonable agreement with the literature values. However, the axial and radial solids dispersion coefficients measured near the wall were slightly lower than the radially averaged values in the literature.

关键词： Particle image velocimetry (PIV) Dispersion coefficient Autocorrelation Turbulence Anisotrnpy

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