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Contact Dermatitis With the Homoeopathic Medicine Calendula officinalis:A Rare Case Report

International Journal of Dermatology and Venereology 2023年第2期6卷 115-117页

作者： ankit Bhardwaj Shoma Mukherjee Mukesh Manjhi Department of Pharmacology UCMS&GTB HospitalDilshad GardenDelhi 110095India Department of Pharmacology School of Medical Sciences&ResearchSharda University Knowledge Park-ⅢGreater NoidaUP201310India Department of Dermatology&Venerology Hamdard Institute of Medical Sciences&Research New Delhi 110062India

Introduction:Herbal medicines and other traditional medicines are well accepted in India and are readily available as over-the-counter *** their increased use,the safety and quality of homoeopathic medicines have become a major concern for health authorities,pharmaceutical industries,and *** is difficult to assess the adverse effects of homoeopathic medicines due to a lack of scientific evidence regarding their safety and efficacy in clinical trials or post-marketing ***,we reported a patient with contact dermatitis due to the homoeopathic medicine Calendula *** presentation:A 33-year-old previously healthy woman presented with pruritus,redness,and swelling over the entire face and upper *** symptoms developed within about 1 hour after the use of a homoeopathic skin ointment containing 2%Calendula officinalis as the major ingredient in an aqueous *** examination revealed periorbital edema and facial swelling with multiple vesicular eruptions over erythematous edematous plaques on the face.A clinical diagnosis of contact dermatitis was ***:Many herbal preparations in India are available without safety *** officinalis extract(oil expressed from seeds)is used in various skin *** exact allergens present in Calendula officinalis are unknown,but the flowers reportedly contain a variety of phenolic acids and phenylpropanoids that have elicited contact ***:Anecdotal case reports of accidental exposure/sensitization and experimental studies provide sufficient evidence to confirm the causal relationship between contact dermatitis with Calendula *** surveillance of all homoeopathic medicines should be mandatory,and the availability of such preparations as over-the-counter drugs must be restricted.

关键词： homoeopathic medicine Calendula officinalis contact dermatitis

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病例报告:焦虑障碍出现幻视一例（英文）

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上海精神医学 2015年第2期27卷 126-129页

作者： Ankur SACHDEVA ankit SAXENA Manish KANDPAL Post Graduate Institute of Medical Education and Research

焦虑障碍患者很少出现幻视。本病例报告描述了一位男性患者,36岁,患有社交恐惧症和伴惊恐发作的广场恐惧症。该患者幻视明显,令其深受困扰、功能受损。用舍曲林200 mg/d、氯硝西泮1mg/d和普萘洛尔20 mg/d治疗一个月后,患者的焦虑和幻视... 详细信息

焦虑障碍患者很少出现幻视。本病例报告描述了一位男性患者,36岁,患有社交恐惧症和伴惊恐发作的广场恐惧症。该患者幻视明显,令其深受困扰、功能受损。用舍曲林200 mg/d、氯硝西泮1mg/d和普萘洛尔20 mg/d治疗一个月后,患者的焦虑和幻视缓解,能继续工作,恢复社会生活。本报告强调这样一个事实,即幻视并不一定预示着精神病性障碍,很多精神障碍都可能出现视幻觉。如果非精神病性障碍患者出现幻视,那么治疗这些非精神病性障碍通常也能同时缓解相关的幻视,而无需使用抗精神病药物。详细分析此类罕见病例有助于加深对精神病样症状的病理机制的认识。

关键词：病例报告焦虑精神障碍氯硝西泮普萘洛尔发病机制精神病幻觉

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Assessment of Above-and Below-Ground Carbon Pools in a Tropical Dry Deciduous Forest Ecosystem of Bhopal, India

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Chinese Journal of Urban and Environmental Studies 2020年第4期8卷 60-76页

作者： Subhajit KARMAKAR Bhabani Sankar PRADHAN ankit BHARDWAJ B.K.PAVAN Rishabh CHATURVEDI Pradeep CHAUDHRY Indian Institute of Forest Management

This study estimated 18.35 Mg C/ha in standing biomass of natural forest and 15 Mg C/ha in Hardwickia binata Roxb. plantation in a tropical dry deciduous forest located in the capital city of Madhya Pradesh. The study area of Indian Institute of Forest Management(IIFM), Bhopal,resembled a degraded dry scrubland in 1988 and for over about three decades, the degraded forest recovered remarkably, and ecological processes evolved favorably with canopy cover reaching over 60% in some patches and about 50% in general at most part of the campus. The study was conducted in 18 randomly laid plots in natural forest and over one-acre(0.405-ha) plantation area of Hardwickia binata for assessing the above-ground biomass, below-ground biomass and subsequent carbon content. The lower-diameter classes accounted for the maximum above-ground biomass, basal area and tree density. The forest is predominantly occupied by Leucaena leucocephala, an exotic tree species which showed higher standing biomass carbon storage of 3.79 Mg C/ha followed by Holoptelea integrifolia(2.11 Mg C/ha), Azadirachta indica(1.29 Mg C/ha),Gardenia latifolia(1.26 Mg C/ha) and Lannea coromandelica(1.24 Mg C/ha) besides Hardwickia binata plantation(15 Mg C/ha). It is recommended to plant and promote local native tree species in the urban forests of tropical dry deciduous nature as a means to mitigate climate change effects.

关键词： Above-ground biomass carbon stock basal area urban forest tropical dry deciduous forest carbon dioxide sequestration

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Role of artificial intelligence in gastrointestinal surgery

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Artificial Intelligence in Cancer 2024年第2期5卷 1-9页

作者： ankit Shukla Rajesh Chaudhary Nishant Nayyar Department of Surgery Dr Rajendra Prasad Government Medical CollegeKangra 176001Himachal PradeshIndia Department of Renal Transplantation Dr Rajendra Prasad Government Medical CollegeKangra 176001India Department of Radiology Dr Rajendra Prasad Government Medical CollegeKangra 176001Himachal PradeshIndia

Artificial intelligence is rapidly evolving and its application is increasing day-byday in the medical *** application of artificial intelligence is also valuable in gastrointestinal diseases,by calculating various scoring systems,evaluating radiological images,preoperative and intraoperative assistance,processing pathological slides,prognosticating,and in treatment *** field has a promising future and can have an impact on many management *** this minireview,we aimed to determine the basics of artificial intelligence,the role that artificial intelligence may play in gastrointestinal surgeries and malignancies,and the limitations thereof.

关键词： Machine learning Gastrointestinal surgery Radiology Artificial neural network Deep learning

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富血小板血浆治疗骨不连临床应用的系统综述

富血小板血浆治疗骨不连临床应用的系统综述

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作者： ankit Shrivastava 吉林大学

学位级别：硕士

背景:长骨骨不连发生率是很高的,不同于每种骨折和急性骨折的治疗方法。虽然骨不连病因不是很清楚,发病机制很少有证据表明,由于机械性不稳和骨周围血管的组成。骨不连治疗仍然是一个挑战,治疗骨折愈合期长和困难,为获得骨折愈合,需要... 详细信息

背景:长骨骨不连发生率是很高的,不同于每种骨折和急性骨折的治疗方法。虽然骨不连病因不是很清楚,发病机制很少有证据表明,由于机械性不稳和骨周围血管的组成。骨不连治疗仍然是一个挑战,治疗骨折愈合期长和困难,为获得骨折愈合,需要医生其中包括许多专业医师和辅助人员来帮助。骨不连的治疗需要反复住院和一些干预措施会产生额外并发症的风险和更大的医疗制度的经济负担。根据临床实践长骨骨不连治疗的金标准是清除纤维组织,骨折端稳定固定,必要时于骨不连部位植入自体髂骨和充分的软组织覆盖。然而,自体骨使用的主要涉及植骨部位有限性和供区发病率.比起髂骨植骨患者反馈RIA取骨在供区处疼痛少。当使用RIA取骨薄皮质处或医师使用铰刀过度获取处,术后骨折风险似乎会增高。在多种研究中间质干细胞已经证明有促进肿瘤生长和转移能力BMP也是刺激血管生成的因素,例如成骨细胞。虽然重组人BMP-2可为骨移植或二次手术的需要提供帮助,但单独治疗骨不连可能没有实质性的作用。同种异体骨移植对患者的吸引力较小,对传染性疾病和污染风险的关注仍然很高。骨折的三个显著但又互相重叠的愈合过程是炎症反应阶段,修复阶段和重新塑性阶段.大多数骨折具有机械性不稳的一些程度和软骨内成骨的过程治愈,骨性骨痂形成期先于软骨模板。最后阶段期间坚强骨痂形成通过产生皮质骨和骨小梁。骨折治愈被破坏通过不同患者的全身因素和骨折局部因素涉及损伤组织的物理和机械性原因的结果修复.几个生理和生物力学步骤需要在分子和细胞水平达更广泛活动范围的相互作用。随着骨再生的细胞机制的理解,生物环境可以通过成骨、骨诱导材料介绍的改进,和骨传导性能。为了取得进一步的成功率,共同搅拌剂提高了种植体骨整合的潜力,恢复骨组织的功能。一种新的方法是重组细胞疗法,它可以减少愈合时间,虽然有些是昂贵的,但有更好的结果。富血小板血浆疗法是一种古老的治疗方法,广泛应用于皮肤科、整形外科和牙科专业。富含血小板的血浆自上世纪90年代通过颌面外科和整形外科应用以来,已被广泛应用于各种临床应用中,因为富含血小板的血浆具有独特的功能,通过细胞的募集、增殖和分化来治疗。正常的富血小板血浆是自体血浆,血小板浓度超过基线,在血浆5ml容积有10×105个血小板/μL.而较低浓度不能依靠提高伤口愈合但似乎很符合逻辑,提高骨移植血小板的浓度,从而促进生长因子的浓度,可以推进到一个更快速、更致密的骨再生。血小板生长因子构成水库对组织愈合的过程中,在各种组织中是非常相似的。然而,富含血小板的血浆在其他组织中使用的原则是明确的,因为血小板代表组织损伤的第一反应,因为他们参与阻止血管出血和触发愈合级联。骨折愈合在很大程度上是一个未知的级联的复杂的生物事件。它涉及细胞内和细胞外分子信号的骨诱导和传导。它是一个多级的修复过程,遵循一个定义的时间和空间序列。作为一个总的了解骨愈合过程通常针对骨折,截骨、植骨融合术,手术。有骨愈合期不同阶段的骨愈合包括血肿期、肉芽组织阶段、骨痂期、重塑期、巩固期、重塑期或重塑期。在细胞水平上的骨愈合具有独特的再生过程包括间充质细胞凝聚,软骨,血管生成和骨形成。许多局部和全身的调节因素,包括生长和分化因子、激素、细胞因子和细胞外基质,与几种类型的细胞相互作用,包括骨和软骨形成的原代细胞或肌间质细胞,在骨折部位或周围收集。不同的阶段有不同的时间段,其血肿大约不到七天的时间在这个过程中发生的断裂、坏死,前体细胞的感觉;期肉芽组织这最后一到两天到三天,和组织细胞进入血管,成纤维细胞的增殖分化,成骨细胞等,但仍在原位骨折是移动;在这个阶段愈伤组织阶段持续四到十二周,有几个步骤,其中矿化的肉芽组织形成愈伤组织和放射图像可见,在这一段时间的断裂是团结的,没有任何运动的骨折碎片的感觉;阶段的重构需要一到两年里层骨由多细胞单位信息基础重构的愈伤组织,愈伤组织经放射学视图轮廓变得致密和明确的规定;最后阶段的建模,需要几年的时间里渐渐的建模和骨膜的骨内骨折部位是从父骨表面得到了很好的区分。大多数骨折具有一定程度的机械稳定性和软骨内骨化过程的治疗,在骨痂形成之前的软骨模板。在最后阶段,硬愈伤组织转化为皮质和骨小梁。骨折愈合也受不同的全身和局部变量的影响,恢复原来的物理和机械性能的受伤组织。它需要的几个生理和生物力学的步骤,反映了广泛的活动,在分子和细胞水平的相互作用。了解骨折愈合的多个复杂的过程,将确保有效的治疗方法。细胞和分子生物学今天提供的调查和理解骨折愈合过程的通行费。正在进行的这方面的研究在分子水平上提高了我们的骨折愈合的理解。在修复过程中,正常胚胎发育途径概括的几种类型细胞的协同作用。所有四个成分的参与,在损伤部位,包括皮质、骨膜、骨髓及外软组织,有助于治疗过程中的不同程度,取决于多个参数,在受伤的组织如生长因子、激素和营养物质、p H、氧分压、电气环境和机械稳定性

关键词：骨不连富含血小板血浆生长因子骨折愈合

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IP Mobility Issues for a Mobile Tele-Robotic System-NEPWAK

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International Journal of Automation and computing 2004年第1期1卷 10-16页

作者： Alexander Ferworn ankit Arora Muhammad Jaseemuddin Network-Centric Applied Research Team Ryerson University CanadaNetwork-Centric Applied Research Team Ryerson University CanadaNetwork-Centric Applied Research Team Ryerson University Canada

The network-centric applied research team (N-CART) is continuing its work on an ambitious project known as the network-enabled powered wheelchair adaptor kit (NEPWAK). It introduces techniques for modifying and using powered wheelchairs as mobile platforms enabling communication and remote control. The wheelchair is equipped with a laptop computer, a CCD camera and a wireless network interface card (NIC) for 802.11b Internet access. The laptop acts as a server allowing network clients to gain access through a custom control interface on the chair. The remote controlling client receives a video and audio feed from the chair and sends control signals for maneuvering. While traveling, the chair is able to change its network association from one access point (AP) to another within the same subnet-the process is known as handoff. However, there is no inter-network handoff mechanism presently available in IP networks. This restricts the mobility of the wheelchair to within the coverage area of the subnet APs. This paper shows that the Internet engineering task force’s (IETF) network layer mobility protocol—Mobile IP suffers from large handoff latencies that can hinder communication between the client and the wheelchair during handoff. Mobile IP alone is not a sufficient solution for a mobile telebotic system such as NEPWAK. An interesting solution to the handoff latency problem comes from the Fast-handover protocol described in Section 4.4 with simulation results in Section 6.2.

关键词： Telebot wheelchair 802.11 Wi-Fi handoff mobile IP fast handover

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Bacterial Surface Layer Proteins: From Moonlighting to Biomimetics: A New Horizonto Lead

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Advances in Bioscience and Biotechnology 2018年第8期9卷 352-372页

作者： Nimisha Gaur ankit Sharma Barkha Singhal School of Biotechnology Gautam Buddha University Greater Noida (U.P.) India

The landmark discovery of moonlighting proteins embarks the significant progress in understanding the biological complexity and their closed-circuit analysis. The growing continuum in the variety of moonlighting functions paved the way for further elucidation of structural-functional aspects of protein evolution and design of proteins with novel functions. Currently, the moonlighting functions in various adhesive properties of surface layer proteins, an essential component of cell surface architecture of archaea and all phylogenetic groups of eubacteria become more prominently recognized. The remarkable credentials of surface layer proteins to self-assemble into supramolecular structures at nano-scale dimension have been exploited for the production of smart biomaterials in the form of biomimetics has been thrust area of research. The finely tuned topological features in terms of shape, size, geometry and surface chemistry of surface layer proteins are crucial for the production of biomimetics. The current developments of biomimetic lipid bilayers and composite membranes find applicability in understanding the functional dynamism of evolutionary relationship of bacterial cell envelopes and vaccine development, drug development and drug delivery. Though the development of biomimetics embraces fascination but faces with technological challenges. The plethora of literature has been available for the moonlighting aspects and nano-technological applications separately but none of the review describes towards the rhythmic transition from moonlighting functions of surface layer proteins of bacteria to biomimetics development and applications. Therefore, this review describes certain basic aspects of moonlighting functions and their mechanism of action, surface layer proteins and their moonlighting functions of commensal bacteria and their transition towards biomimetics. The recent developments of biomimetics based on surface layer proteins have been summarized and also pos

关键词： Moonlighting Biomimetic Surface Layer Proteins Self-Assembly Nano-Biotechnology

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A New Generalized Weibull-Exponential Frailty Model

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Open Journal of Statistics 2017年第1期7卷 84-91页

作者： Ashok Shanubhogue ankit R. Sinojiya Department of Statistics Sardar Patel University Vallabh Vidyanagar India

We have proposed a new generalized Weibull-exponential frailty model which is a general case of classical frailty model suggested by [1] and [2]. In classical frailty model, modeling of hazard rate is considered whereas, in this paper, direct modeling of conditional survival function given the frailty is considered. Simulation study is carried out using E-M algorithm using MATLAB programme. Further we implemented the suggested model on a real life data. As an illustration, we have fitted the model to the data given in [3] which examines the strength of isolated carbon fiber under tensile aload.

关键词： Frailty Proportional Hazard E-M Algorithm Likelihood Ratio Test Goodness of Fit of the Model

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Comparative study of thulium fiber laser versus holmium:yttrium-aluminum-garnet laser for ureteric stone management with semi-rigid ureteroscopy: A prospective, single-center study

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Asian Journal of Urology 2024年第3期11卷 460-465页

作者： ankit Gupta Arvind P.Ganpule Ankush Puri Abhishek G.Singh Ravindra B.Sabnis Mahesh R.Desai Muljibhai Patel Urological Hospital NadiadGujaratIndia

Objective:To compare the efficacy and safety of thulium fiber laser(TFL)and holmium:yttrium-aluminum-garnet(Ho:YAG)laser for ureteric stone management with semi-rigid ***:In a prospective study from January 2020 to December 2021,we compared 40 patients in each group who underwent semi-rigid ureteroscopic lithotripsy with TFL and that with Ho:YAG *** volume,stone density,stone fragmentation rates,total lasing time,total operative time,endoscopic vision,retropulsion and stone free rates were analyzed in both groups and ***:Mean stone volume was comparable in the TFL group and the Ho:YAG laser group(282.45[standard deviation,SD 139.79]mm3 vs.279.49[SD 312.52]mm3;p=0.964).Mean stone density was also comparable in the TFL group and the Ho:YAG laser group(1135.30[SD 317.04]Hounsfield unit vs.1131.75[SD 283.03]Hounsfield unit;p=0.959).The mean stone fragmentation rates calculated as stone volume divided by lasing time were 25.85(SD 10.61)mm3/min and 21.37(SD 14.13)mm3/min in the TFL group and the Ho:YAG laser group,respectively(p=0.113).The mean total lasing time(10.15[SD]4.69 min vs.11.43[SD 4.56]min;p=0.222),mean operative time(25.13[SD 9.51]min vs.25.54[SD 10.32]min;p=0.866),and mean total hospital stay(2.62[SD 0.77]days vs.2.61[SD 0.84]days;p=0.893)were comparable in the TFL group and in the Ho:YAG *** vision was better and retropulsion was less in the TFL *** stone-free rate at 1 month postoperatively was slightly better in the TFL group(100%vs.90%;p=0.095).

关键词： Laser Stone Urolithiasis Thulium Holmium

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Recent advances and applications of deep learning methods in materials science

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npj Computational Materials 2022年第1期8卷 548-573页

作者： Kamal Choudhary Brian DeCost Chi Chen Anubhav Jain Francesca Tavazza Ryan Cohn Cheol Woo Park Alok Choudhary ankit Agrawal Simon J.L.Billinge Elizabeth Holm Shyue Ping Ong Chris Wolverton Materials Science and Engineering Division National Institute of Standards and TechnologyGaithersburgMD20899USA Theiss Research La JollaCA92037USA DeepMaterials LLC Silver SpringMD20906USA Material Measurement Science Division National Institute of Standards and TechnologyGaithersburgMD20899USA Department of NanoEngineering University of California San DiegoSan DiegoCA92093USA Energy Technologies Area Lawrence Berkeley National LaboratoryBerkeleyCAUSA Department of Materials Science and Engineering Carnegie Mellon UniversityPittsburghPA15213USA Department of Materials Science and Engineering Northwestern UniversityEvanstonIL60208USA Department of Electrical and Computer Engineering Northwestern UniversityEvanstonIL60208USA Department of Applied Physics and Applied Mathematics and the Data Science Institute Fu Foundation School of Engineering and Applied SciencesColumbia UniversityNew YorkNY10027USA

Deep learning(DL)is one of the fastest-growing topics in materials data science,with rapidly emerging applications spanning atomistic,image-based,spectral,and textual data *** allows analysis of unstructured data and automated identification of *** recent development of large materials databases has fueled the application of DL methods in atomistic prediction in *** contrast,advances in image and spectral data have largely leveraged synthetic data enabled by high-quality forward models as well as by generative unsupervised DL *** this article,we present a high-level overview of deep learning methods followed by a detailed discussion of recent developments of deep learning in atomistic simulation,materials imaging,spectral analysis,and natural language *** each modality we discuss applications involving both theoretical and experimental data,typical modeling approaches with their strengths and limitations,and relevant publicly available software and *** conclude the review with a discussion of recent cross-cutting work related to uncertainty quantification in this field and a brief perspective on limitations,challenges,and potential growth areas for DL methods in materials science.

关键词： learning limitations textual

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