Contact Dermatitis With the Homoeopathic Medicine Calendula officinalis:A Rare Case Report

作     者：Ankit Bhardwaj Shoma Mukherjee Mukesh Manjhi Ankit Bhardwaj;Shoma Mukherjee;Mukesh Manjhi

作者机构：Department of PharmacologyUCMS>B HospitalDilshad GardenDelhi 110095India Department of PharmacologySchool of Medical Sciences&ResearchSharda University Knowledge Park-ⅢGreater NoidaUP201310India Department of Dermatology&Venerology Hamdard Institute of Medical Sciences&ResearchNew Delhi 110062India 

出 版 物：《International Journal of Dermatology and Venereology》 (国际皮肤性病学杂志（英文）)

年 卷 期：2023年第6卷第2期

页      面：115-117页

核心收录：

学科分类：1002[医学-临床医学] 100206[医学-皮肤病与性病学] 10[医学] 

主　　题：homoeopathic medicine Calendula officinalis contact dermatitis 

摘      要：Introduction:Herbal medicines and other traditional medicines are well accepted in India and are readily available as over-the-counter *** their increased use,the safety and quality of homoeopathic medicines have become a major concern for health authorities,pharmaceutical industries,and *** is difficult to assess the adverse effects of homoeopathic medicines due to a lack of scientific evidence regarding their safety and efficacy in clinical trials or post-marketing ***,we reported a patient with contact dermatitis due to the homoeopathic medicine Calendula *** presentation:A 33-year-old previously healthy woman presented with pruritus,redness,and swelling over the entire face and upper *** symptoms developed within about 1 hour after the use of a homoeopathic skin ointment containing 2%Calendula officinalis as the major ingredient in an aqueous *** examination revealed periorbital edema and facial swelling with multiple vesicular eruptions over erythematous edematous plaques on the face.A clinical diagnosis of contact dermatitis was ***:Many herbal preparations in India are available without safety *** officinalis extract(oil expressed from seeds)is used in various skin *** exact allergens present in Calendula officinalis are unknown,but the flowers reportedly contain a variety of phenolic acids and phenylpropanoids that have elicited contact ***:Anecdotal case reports of accidental exposure/sensitization and experimental studies provide sufficient evidence to confirm the causal relationship between contact dermatitis with Calendula *** surveillance of all homoeopathic medicines should be mandatory,and the availability of such preparations as over-the-counter drugs must be restricted.