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Incidence, Mortality, and Epidemiology of Leukemia in South Asia: An Ecological Study

Open Journal of Epidemiology 2023年第1期13卷 73-82页

作者： Rakibul Hasan Rifat Md. Shah Poran Saiful Islam anika tabassum sumaya Md. Mozahidul Alam Md Rashedur Rahman Bangladesh Health Research Initiative Mirpur Dhaka Bangladesh Department of Pharmacy Primeasia University Banani Dhaka Bangladesh Department of Pharmacy Jahangirnagar University Savar Dhaka Bangladesh

Background: Nowadays cancer is a buzzword in every corner of the world. Back a few decades, cancer was not that much known to the people of South Asia let alone known of Leukemia. Many countries in the South Asian region are designated as developing countries. Hence, the deficiency of diagnosis system, treatment, management, and lack of knowledge about leukemia in this region are major problems. Therefore, the incidence rate, mortality rate, and several deaths are increasing day by day. Methods: This cross-sectional study is aimed to investigate the incidence and mortality of leukemia in South Asian Countries for the year 2020 by acquiring data from the global cancer project (GLOBOCAN2020) accessible at https://***. Results: In South Asia, 1,733,573 cancer cases were documented in 2020 where 62,163 cases were leukemia related. The highest incidence rate was reported in Pakistan (4.3 in 1,000,000) and Sri Lanka (4.1 in 1,000,000) and the lowest in Bangladesh (1.8 in 1,000,000) and Nepal (2.0 in 1,000,000). On the other hand, 1,124,875 death had been reported in 2020, where 45,707 (4.1%) death was associated with leukemia. Pakistan (3.4 in 1,000,000) and Maldives (3.1 in 1,000,000) had the highest death and lowest in Bangladesh (1.4 in 1,000,000) and Nepal (1.5 in 1,000,000). Adults aged from 60 - 85 years old have the highest rate of incidence and mortality rate in all countries except Nepal. Conclusions: Leukemia is one of the major concerning cancer of all ages people in South Asia, the situation and related risk factors information can be helpful to reduce death through proper treatment.

关键词： Leukemia Blood Cancer South Asia Incidence Mortality Epidemiology

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Snapshot multispectral imaging using a diffractive optical network

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Light(Science & Applications) 2023年第5期12卷 789-808页

作者： Deniz Mengu anika tabassum Mona Jarrahi Aydogan Ozcan Electrical and Computer Engineering Department University of CaliforniaLos AngelesCA 90095USA Bioengineering Department University of CaliforniaLos AngelesCA 90095USA California NanoSystems Institute University of CaliforniaLos AngelesCA 90095USA

Multispectral imaging has been used for numerous applications in e.g.,environmental monitoring,aerospace,defense,and ***,we present a diffractive optical network-based multispectral imaging system trained using deep learning to create a virtual spectral filter array at the output image *** diffractive multispectral imager performs spatially-coherent imaging over a large spectrum,and at the same time,routes a pre-determined set of spectral channels onto an array of pixels at the output plane,converting a monochrome focal-plane array or image sensor into a multispectral imaging device without any spectral filters or image recovery ***,the spectral responsivity of this diffractive multispectral imager is not sensitive to input polarization *** numerical simulations,we present different diffractive network designs that achieve snapshot multispectral imaging with 4,9 and 16 unique spectral bands within the visible spectrum,based on passive spatially-structured diffractive surfaces,with a compact design that axially spans ~72λ_(m),where λ_(m) is the mean wavelength of the spectral band of ***,we experimentally demonstrate a diffractive multispectral imager based on a 3D-printed diffractive network that creates at its output image plane a spatially repeating virtual spectral filter array with 2×2=4 unique bands at terahertz *** to their compact form factor and computation-free,power-efficient and polarization-insensitive forward operation,diffractive multispectral imagers can be transformative for various imaging and sensing applications and be used at different parts of the electromagnetic spectrum where high-density and wide-area multispectral pixel arrays are not widely available.

关键词： spectrum spectral spatially

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Synthesis of new two-dimensional titanium carbonitride Ti_(2)C_(0.5)N_(0.5)T_(x)MXene and its performance as an electrode material for sodium-ion battery

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InfoMat 2021年第12期3卷 1422-1430页

作者： Kun Liang anika tabassum Ahmad Majed Chaochao Dun Feipeng Yang Jinghua Guo Kaitlyn Prenger Jeffrey JUrban Michael Naguib Department of Physics and Engineering Physics Tulane UniversityNew OrleansLouisianaUSA The Molecular Foundry Lawrence Berkeley National LaboratoryBerkeleyCaliforniaUSA Advanced Light Source Lawrence Berkeley National LaboratoryBerkeleyCaliforniaUSA

Two-dimensional(2D)layered transition metal carbides/nitrides,called MXenes,are attractive alternative electrode materials for electrochemical energy *** to their metallic electrical conductivity and low ion dif-fusion barrier,MXenes are promising anode materials for sodium-ion batteries(SIBs).Herein,we report on a new 2D carbonitride MXene,viz.,Ti_(2)C_(0.5)N_(0.5)T_(x)(T_(x) stands for surface terminations),and the only second carbonitride after Ti_(3) CNT_(x) so far.A new type of in situ HF(HCl/KF)etching condition was employed to synthesize multilayer Ti_(2)C_(0.5)N_(0.5)T_(x) powders from Ti_(2)AlC_(0.5)N_(0.5).Spontaneous intercalation of tetramethylammonium followed by sonication in water allowed for large-scale delamination of this new titanium carbonitride into 2D *** Ti_(2)C_(0.5)N_(0.5)T_(x) powders showed higher specific capac-ities and larger electroactive surface area than those of Ti_(2)CT_(x) ***-layer Ti_(2)C_(0.5)N_(0.5)T_(x) powders show a specific capacity of 182 mAh g^(-1) at 20 mA g^(-1),the highest among all reported MXene electrodes as SIBs with excellent cycling stability.

关键词： MXene sodium-ion battery titanium carbonitride two-dimensional

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Two-dimensional titanium carbonitride MXene as a highly efficient electrocatalyst for hydrogen evolution reaction

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Materials Reports(Energy) 2022年第1期2卷 88-95页

作者： Kun Liang anika tabassum Manish Kothakonda Xiaodong Zhang Ruiqi Zhang Brianna Kenney Brent D.Koplitz Jianwei Sun Michael Nagui Department of Physics and Engineering Physics Tulane UniversityNew OrleansLA70118USA Department of Chemistry Tulane UniversityNew OrleansLA70118USA

In this paper,we report,for the first time,on the electrochemical catalytic activity of 2D titanium carbonitride MXene for hydrogen evolution reaction(HER).According to our study,2D titanium carbonitride exhibited much higher electrocatalytic activity than its carbide analogues,achieving an onset overpotential of 53 mV and Tafel slope of 86 mV dec^(-1),superior to the titanium carbide with onset overpotential of 649 mV and Tafel slope of 303 mV dec^(-1).The obtained onset overpotential for 2D titanium carbonitride is lower than those of all the reported transition metal carbides MXene catalysts without additives,so *** functional theory calculations were conducted to further understand the electrochemical *** calculation results show that a greater number of occupied states are active for Ti_(3)CNO_(2),revealing free energy for the adsorption of atomic hydrogen closer to 0 than that of Ti_(3)C_(2)O_(2).Both experimental and calculation studies demonstrate the excellent electrocatalytic behavior of titanium *** investigation of 2D titanium carbonitride opens up a promising paradigm for the conscious design of high-performance non-precious metal catalyst for hydrogen generation.

关键词： Two-dimensional Titanium carbonitride MXene Nanosheets Hydrogen evolution Electrocatalyst Density functional theory calculation

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A Holistic Secure Communication Mechanism Using a Multilayered Cryptographic Protocol to Enhanced Security

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Computers, Materials & Continua 2024年第3期78卷 4417-4452页

作者： Fauziyah Zhaoshun Wang Mujahid tabassum School of Computer and Communication Engineering University of Science and TechnologyBeijing100000China Noroff School of Technology and Digital Media(Noroff Accelerate) Noroff University CollegeKristiansand4612Norway

In an era characterized by digital pervasiveness and rapidly expanding datasets,ensuring the integrity and reliability of information is *** cyber threats evolve in complexity,traditional cryptographic methods face increasingly sophisticated *** article initiates an exploration into these challenges,focusing on key exchanges(encompassing their variety and subtleties),scalability,and the time metrics associated with various cryptographic *** propose a novel cryptographic approach underpinned by theoretical frameworks and practical *** to this approach is a thorough analysis of the interplay between Confidentiality and Integrity,foundational pillars of information *** method employs a phased strategy,beginning with a detailed examination of traditional cryptographic processes,including Elliptic Curve Diffie-Hellman(ECDH)key *** also delve into encrypt/decrypt paradigms,signature generation modes,and the hashes used for Message Authentication Codes(MACs).Each process is rigorously evaluated for performance and *** gain a comprehensive understanding,a meticulously designed simulation was conducted,revealing the strengths and potential improvement areas of various ***,our cryptographic protocol achieved a confidentiality metric of 9.13 in comprehensive simulation runs,marking a significant advancement over existing ***,with integrity metrics at 9.35,the protocol’s resilience is further *** metrics,derived from stringent testing,underscore the protocol’s efficacy in enhancing data security.

关键词： Cryptographic security privacy preservation decryption integrity

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An advanced anaerobic biofilter with effluent recirculation for phenol removal and methane production in treatment of coal gasification wastewater

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Journal of Environmental Sciences 2016年第9期28卷 23-33页

作者： Yajie Li Salma tabassum Zhenjia Zhang School of Environmental Science and Engineering Shanghai Jiao Tong University LCM-Laboratory of Catalysis and Materials Associate Laboratory LSRE-LCMDepartamento de Engenharia QuímicaFaculdade de EngenhariaUniversidade do Porto

An advanced anaerobic biofilter（AF） was introduced for the treatment of coal gasification wastewater（CGW）,and effluent recirculation was adopted to enhance phenol removal and methane *** results indicated that AF was reliable in treating diluted CGW,while its efficiency and stability were seriously reduced when directly treating raw ***,its performance could be greatly enhanced by effluent *** optimal effluent recirculation of 0.5 to the influent,concentrations of chemical oxygen demand（COD） and total phenol in the effluent could reach as low as 234.0 and 14.2 mg/L,***,the rate of methane production reached 169.0 m L CH_4/L/*** CGW seemed to restrain the growth of anaerobic microorganisms,especially methanogens,the inhibition was temporary and reversible,and anaerobic bacteria presented strong *** activities of methanogens cultivated in CGW could quickly recover on feeding with glucose wastewater（GW）.However,the adaptability of anaerobic bacteria to the CGW was very poor and the activity of methanogens could not be improved by long-term *** analysis using the Haldane model,it was further confirmed that high effluent recirculation could result in high activity for hydrolytic bacteria and substrate affinity for toxic matters,but only suitable effluent recirculation could result in high methanogenic activity.

关键词： Coal gasification wastewater Effluent recirculation Methane production Anaerobic biofilters

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Inhibitory effect of high phenol concentration in treating coal gasification wastewater in anaerobic biofilter

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Journal of Environmental Sciences 2018年第2期30卷 207-215页

作者： Yajie Li Salma tabassum Chunfeng Chu Zhenjia Zhang School of Environmental Science and Engineering Suzhou University of Science and Technology School of Environmental Science and Engineering Shanghai Jiao Tong University

In this paper, the inhibition of methanogens by phenol in coal gasification wastewater（CGW）was investigated by both anaerobic toxicity tests and a lab-scale anaerobic biofilter reactor（AF）. The anaerobic toxicity tests indicated that keeping the phenol concentration in the influent under 280 mg/L could maintain the methanogenic activity. In the AF treating CGW,the result showed that adding glucose solution as co-substrate could be beneficial for the quick start-up of the reactor. The effluent chemical oxygen demand（COD） and total phenol reached1200 and 100 mg/L, respectively, and the methane production rate was 175 m L CH4/g COD/***, if the concentration of phenol was increased, the inhibition of anaerobic micro-organisms was irreversible. The threshold of total phenol for AF operation was 200–250 mg/L. The extracellular polymeric substances（EPS） and particle size distribution of anaerobic granular sludge in the different stages were also examined, and the results indicated that the influence of toxicity in the system was more serious than its effect on flocculation of EPS. Moreover, the proportion of small size anaerobic granular sludge gradually increased from10.2% to 34.6%. The results of high through-put sequencing indicated that the abundance of the Chloroflexi and Planctomycetes was inhibited by the toxicity of the CGW, and some shifts in the microbial community were observed at different stages.

关键词： Inhibition Phenol Co-digestion Anaerobic biofilters Coal gasification wastewater

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DEAD-box RNA helicases with special reference to p68:Unwinding their biology,versatility,and therapeutic opportunity in cancer

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Genes & Diseases 2023年第4期10卷 1220-1241页

作者： Shaheda tabassum Mrinal K.Ghosh Cancer Biology and Inflammatory Disorder Division Council of Scientific and Industrial Research-Indian Institute of Chemical Biology(CSIR-IICB)TRUE CampusSalt LakeKolkata 700091India

In the era of advancement,the entire world continues to remain baffled by the increased rate of progression of *** has been an unending search for novel thera-peutic targets and prognostic markers to curb the oncogenic *** DEAD-box RNA he-licases are a large family of proteins characterized by their evolutionary conserved D-E-A-D(Asp-Glu-Ala-Asp)domain and merit consideration in the oncogenic *** perform multidimensional functions in RNA metabolism and also in the pathology of *** bio-logical role ranges from ribosome biogenesis,RNA unwinding,splicing,modification of second-ary and tertiary RNA structures to acting as transcriptional coactivators/repressors of various important oncogenic *** also play a crucial role in accelerating oncogenesis by pro-moting cell proliferation and ***5(p68)is one of the archetypal members of this family of proteins and has gained a lot of attention due to its oncogenic *** is found to be overexpressed in major cancer types such as colon,brain,breast,and prostate *** exhibits its multifaceted nature by not only coactivating genes implicated in cancers but also mediating crosstalk across major signaling pathways in ***,in this review,we aim to illustrate a comprehensive overview of DEAD-box RNA helicases especially p68 by focusing on their multifaceted roles in different cancers and the various signaling pathways affected by ***,we have also briefly discoursed the therapeutic interventional approaches with the DEAD-box RNA helicases as the pharmacological targets for designing in-hibitors to pave way for cancer therapy.

关键词： Cancer DDX5 DEAD-box RNA helicases Gene expression Oncogene Signaling Therapy Transcription factor

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Therapeutic importance of hydrogen sulfide in age-associated neurodegenerative diseases

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Neural Regeneration Research 2020年第4期15卷 653-662页

作者： Rubaiya tabassum Na Young Jeong Junyang Jung Department of Anatomy and Cell Biology College of MedicineDong-A UniversityBusanKorea Department of Medicine Graduate SchoolDong-A UniversityBusanKorea Department of Anatomy and Neurobiology College of MedicineKyung Hee UniversitySeoulKorea

Hydrogen sulfide(H2S)is a gasotransmitter that acts as an antioxidant and exhibits a wide variety of cytoprotective and physiological functions in age-associated *** of the major causes of age-related diseases is oxidative *** recent years,the importance of H2S has become clear,although its antioxidant function has not yet been fully *** enzymes cystathionineβ-synthase,cystathionineγ-lya-se,and 3-mercaptopyruvate sulfurtransferase are involved in the enzymatic production of ***,H2S was considered a neuromodulator,given its role in long-term hippocampal potentiation,but it is now also recognized as an antioxidant in age-related *** to aerobic metabolism,the central nervous system is vulnerable to oxidative stress in brain aging,resulting in age-associated degenerative diseases.H2S exerts its antioxidant effect by limiting free radical reactions through the activation of antioxidant enzymes,including superoxide dismutase,catalase,and glutathione peroxidase,which protect against the effects of aging by regulating apoptosis-related genes,including p53,Bax,and *** review explores the implications and mechanisms of H2S as an antioxidant in age-associated neurodegenerative diseases,including Alzheimer’s disease,Parkinson’s disease,Huntington’s disease,and Down syndrome.

关键词： 3-mercaptopyruvate sulfurtransferase aging antioxidant cystathionineβ-synthase cystathionineγ-lyase glutathione hydrogen sulfide neurodegenerative disease oxidative stress reactive oxygen species

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Potential role of tubulin glutamylation in neurodegenerative diseases

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Neural Regeneration Research 2024年第6期19卷 1191-1192页

作者： Abdullah Md.Sheikh Shatera tabassum Department of Laboratory Medicine Shimane University Faculty of MedicineShimaneJapan

The differentiation of neuronal stem cells into mature neurons is a complex process that involves both structural and functional *** cells undergo differentiation,there are notable functional changes,including the expression of various transcription factors,cytokines,and ***,structural changes occur as the cells develop various processes from the cell body and establish synaptic contacts with other cells.

关键词： diseases degenerative cytokines

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