检索结果-南通市图书馆

Splanchnic vasodilation and hyperdynamic circulatory syndrome in cirrhosis

World Journal of Gastroenterology 2014年第10期20卷 2555-2563页

作者： Massimo Bolognesi Marco Di Pascoli Alberto Verardo angelo gatta Department of Internal Medicine-DIMED University of Padua Azienda Ospedaliera Università di Padova 35128 Padova Italy

Portal hypertension is a clinical syndrome which leads to several clinical complications, such as the formation and rupture of esophageal and/or gastric varices, ascites, hepatic encephalopathy and hepato-renal syndrome. In cirrhosis, the primary cause of the increase in portal pressure is the enhanced resistance to portal outflow. However, also an increase in splanchnic blood flow worsens and maintains portal hypertension. The vasodilatation of arterial splanchnic vessels and the opening of collateral circulation are the determinants of the increased splanchnic blood flow. Several vasoactive systems/substances, such as nitric oxide, cyclooxygenase-derivatives, carbon monoxide and endogenous cannabinoids are activated in portal hypertension and are responsible for the marked splanchnic vasodilatation. Moreover, an impaired reactivity to vasoconstrictor systems, such as the sympathetic nervous system, vasopressin, angiotensin II and endothelin-1, plays a role in this process. The opening of collateral circulation occurs through the reperfusion and dilatation of preexisting vessels, but also through the generation of new vessels. Splanchnic vasodilatation leads to the onset of the hyperdynamic circulatory syndrome, a syndrome which occurs in patients with portal hypertension and is characterized by increased cardiac output and heart rate, and decreased systemic vascular resistance with low arterial blood pressure. Understanding the pathophysiology of splanchnic vasodilatation and hyperdynamic circulatory syndrome is mandatory for the prevention and treatment of portal hypertension and its severe complications.

关键词： Portal hypertension Splanchnic flow Splenic circulation Nitric oxide Autonomic dysfunction Cirrhosis Hyperdynamic circulatory syndrome

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cost-effectiveness analysis of beta-blockers vs endoscopic surveillance in patients with cirrhosis and small varices

引用

World Journal of Gastroenterology 2014年第30期20卷 10464-10469页

作者： Lorenza Di Pascoli Alessra Buja Massimo Bolognesi Sara Montagnese angelo gatta Dario Gregori Carlo Merkel Hepatic Hemodynamic Laboratory and Clinica Medica 5 Department of MedicineUniversity of Padua35128 PadovaItaly Laboratory of Epidemiological Methodology and Biostatistics Department of Environmental Medicine and Public HealthUniversity of Padua35128 PadovaItaly

AIM: To evaluate the most cost-effectiveness strategy for preventing variceal growth and bleeding in patients with cirrhosis and small esophageal varices.

关键词： Pharmaco-economical analysis Cirrhosis Esophageal varices Variceal bleeding Primary prophylaxis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Covert hepatic encephalopathy: Agreement and predictive validity of different indices

引用

World Journal of Gastroenterology 2014年第42期20卷 15756-15762页

作者： Sara Montagnese Esmeralda Balistreri Sami Schiff Michele De Rui Paolo Angeli Giacomo Zanus Umberto Cillo Giancarlo Bombonato Massimo Bolognesi David Sacerdoti angelo gatta Carlo Merkel Piero Amodio Department of Medicine University of Padova Department of Surgical Oncological and Gastroenterological Sciences University of Padova

AIM: To investigate the agreement and prognostic value of different measures of covert hepatic encephalopathy (CHE).

关键词： Hepatic encephalopathy Electroencephalography Psychometry Ammonia Liver cirrhosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Occupational exposures and colorectal cancers:A quantitative overview of epidemiological evidence

引用

World Journal of Gastroenterology 2014年第35期20卷 12431-12444页

作者： Enrico Oddone Carlo Modonesi Gemma gatta Department of Public Health Experimental and Forensic MedicineOccupational Medicine UnitUniversity of Pavia Department of Biosciences Natural History MuseumUniversity of Parma Department of Preventive and Predictive Medicine Evaluative Epidemiology UnitFondazione IRCCS Istituto Nazionale dei Tumori

A traditional belief widespread across the biomedical community was that dietary habits and genetic predisposition were the basic factors causing colorectal *** more recent times,however,a growing evidence has shown that other determinants can be very important in increasing(or reducing) incidence of this *** hypothesis that environmental and occupational risk factors are associated with colorectal cancer is gaining ground,and high risks of colorectal cancer have been reported among workers in some industrial *** aim of this study was to investigate the epidemiologic relationship between colorectal cancer and occupational exposures to several industrial activities,by means of a scientific literature review and *** work pointed out increased risks of colorectal cancer for labourers occupied in industries with a wide use of chemical compounds,such as leather(RR = 1.70,95%CI:1.24-2.34),basic metals(RR = 1.32,95%CI:1.07-1.65),plastic and rubber manufacturing(RR = 1.30,95%CI:0.98-1.71 and RR = 1.27,95%CI:0.92-1.76,respectively),besides workers in the sector of repair and installation of machinery exposed to asbestos(RR = 1.40,95%CI:1.07-1.84).Based on our results,the estimated crude excess risk fraction attributable to occupational exposure ranged from about 11% to about 15%.However,homogeneous pattern of association between colorectal cancer and industrial branches did not emerge from this review.

关键词： Colorectal cancer Occupational exposures Public health Chemical compounds Basic metals Meta analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Can endoscopic atrophy predict histological atrophy? Historical study in United Kingdom and Japan

引用

World Journal of Gastroenterology 2015年第46期21卷 13113-13123页

作者： Shin Kono Takuji Gotoda Shigeaki Yoshida Ichiro Oda Hitoshi Kondo Luigi gatta Greg Naylor Michael Dixon Fuminori Moriyasu Anthony Axon Department of Gastroenterology and Hepatology Tokyo Medical University Aomori Prefectural Central Hospital Endoscopy Division National Cancer Center Hospital Center for Digestive Diseases Tonan Hospital Gastroenterology and Digestive Endoscopy Unit Versilia Hospital Chesterfield Royal Hospital Academic Unit of Pathology University of Leeds Centre for Digestive Disease Leeds General Infirmary

AIM: To assess the diagnostic concordance between endoscopic and histological atrophy in the United Kingdom and ***: Using published data,a total of 252 patients,126 in the United Kingdom and 126 in Japan,aged 20 to 80 years,were evaluated. The extent of endoscopic atrophy was classified into five subgroups according to a modified Kimura-Takemoto classification system and was compared with histological findings of atrophy at five biopsy sites according to the updated Sydney ***: The strength of agreement of the extent of atrophy between histology and visual endoscopic inspection showed good reproducibili ty,wi th a weighted kappa value of 0.76(P < 0.001). Multivariate analysis showed that three factors were associated with decreased concordance: Japanese ethnicity [odds ratio(OR) 0.22,95% confidence interval(CI) 0.11-0.43],older age(OR = 0.32,95%CI: 0.16-0.66) and endoscopic atrophy(OR = 0.10,95%CI: 0.03-0.36). The strength of agreement between endoscopic and histological atrophy,assessed by cancer risk-oriented grading,was reproducible,with a kappa value of 0.81(95%CI: 0.75-0.87). Only nine patients(3.6%) were endoscopically underdiagnosed with antral predominant rather than extensive atrophy and were considered false ***: Endoscopic grading can predict histological atrophy with few false negatives,indicating that precancerous conditions can be identified during screening endoscopy,particularly in patients in western countries.

关键词： Gastritis Atrophy Histology Endoscopy Diagnosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Gelatin-biofermentative unsulfated glycosaminoglycans semi-interpenetrating hydrogels via microbial-transglutaminase crosslinking enhance osteogenic potential of dental pulp stem cells

引用

Regenerative Biomaterials 2021年第3期8卷 110-123页

作者： Annalisa La gatta Virginia Tirino Marcella Cammarota Marcella La Noce Antonietta Stellavato Anna Virginia Adriana Pirozzi Marianna Portaccio Nadia Diano Luigi Laino Gianpaolo Papaccio Chiara Schiraldi Dipartimento di Medicina Sperimentale Universita`della Campania“Luigi Vanvitelli”via L.De Crecchio 7Naples 80138Italy Dipartimento Multidisciplinare di Specialita’Medico-Chirurgiche e Odontoiatriche via Luigi De Crecchio6Napoli 80138Italy

Gelatin hydrogels by microbial-transglutaminase crosslinking are being increasingly exploited for tissue engineering,and proved high potential in bone *** study aimed to evaluate,for the first time,the combination of enzymatically crosslinked gelatin with hyaluronan and the newly developed biotechnological chondroitin in enhancing osteogenic *** enzymatic crosslinking was carried out in the presence of hyaluronan or of a hyaluronan–chondroitin mixture,obtaining semi-interpenetrating *** latter proved lower swelling extent and improved stiffness compared to the gelatin matrix alone,whilst maintaining high *** heteropolysaccharides were retained for 30 days in the hydrogels,thus influencing cell response over this *** evaluate the effect of hydrogel composition on bone regeneration,materials were seeded with human dental pulp stem cells and osteogenic differentiation was *** expression of osteocalcin(OC)and osteopontin(OPN),both at gene and protein level,was evaluated at 7,15 and 30 days of *** electron microscopy(SEM)and two-photon microscope observations were performed to assess bone-like extracellular matrix(ECM)deposition and to observe the cell penetration *** the presence of the heteropolysaccharides,OC and OPN expression was upregulated and a higher degree of calcified matrix formation was *** with hyaluronan and chondroitin improved both the biophysical properties and the biological response of enzymatically crosslinked gelatin,fastening bone deposition.

关键词： hydrogels gelatin hyaluronan biotechnological chondroitin bone regeneration human dental pulp stem cells

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Femoral artery blowout syndrome after inguinal lymphadenectomy for penile cancer

引用

Asian Journal of Urology 2023年第3期10卷 379-381页

作者： Edoardo Agostini Eugenio Pretore Simone Scarcella Daniele Castellani Emanuele gatta Lucio Dell’Atti Andrea B.Galosi Faculty of Medicine School of UrologyPolytechnic University of Marche RegionAnconaItaly Urology Unit Civil Hospital“C.e G.Mazzoni”Ascoli PicenoItaly Urology Unit Azienda Ospedaliera“Ospedali riunitiMarche Nord”PesaroItaly Urology Unit Azienda Ospedaliero Universitaria“Ospedali Riuniti”di AnconaAnconaItaly Vascular Surgery Unit Azienda Ospedaliero Universitaria“Ospedali Riuniti”di AnconaAnconaItaly Azienda Ospedaliero Universitaria“Ospedali Riuniti”di Ancona AnconaItaly

Dear Editor,Inguinal lymphadenectomy represents a crucial step in both staging and treatment of penile cancer and can be curative in some ***,severe morbidity can be high in up to 50%of *** most-reported complications are skin necrosis,wound infection,lymphoedema,and lymphocele[1].In this setting,artery blowout syndrome(ABS)is a complication rarely described,presenting with vessels exposure through wound dehiscence,leading to arterial wall rupture with potentially life-threatening bleeding(Type III ABS).Reports have been described following radiation treatment of the groins or the neck[2,3].We present the first case of femoral artery wall rupture with severe hemorrhage after iliac and inguinal lymphadenectomy for penile cancer in a patient without previous radiation *** consent for case publication was obtained.

关键词： treatment wound treatment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Yield Response to Deficit Irrigation and Partial Root-Zone Drying in Processing Tomato （Lycopersicon esculentum Mill,）

引用

Journal of Agricultural Science and Technology(A) 2012年第2期2卷 209-219页

作者： Eugenio Nardella Marcella Michela Giuliani Giuseppe gatta Antonio De Caro Department of Agro-environmental Sciences Chemistry and Crop Protection （DiSACD） University of Foggia Foggia 71122 Italy

Due to the global expansion of irrigated areas and the limited availability of irrigation water, it is necessary to optimize water use in order to maximize crop yields under water deficit conditions. To evaluate the yield response of two processing tomato hybrids （Ercole and Genius） grown under different irrigation treatments, a field trial was conducted during the 2008 growing season in Southern Italy. Three irrigation treatments were used： the restitution of 70% of maximum evapotranspiration （ETc） both under ＂Deficit Irrigation＂（70DI） and ＂Partial Root-zone Drying＂（70PRD） strategies; full irrigated （FI： 100% ETc）. The two water deficit irrigation treatments （DI and PRD） showed stomatal conductance values lower than FI treatment and saved a substantial amount of water maintaining reasonable marketable yield. Moreover, PRD strategy showed slightly higher ＂Water Use Efficiency＂（WUE） values than DI. Finally, ＂yield response factor＂（Ky） showed always values less than unity, indicating the possibility to adopt, within certain limited condition, both DI and PRD in field-grown processing tomato cultivated in Southern Italy. In conclusion, in our experimental conditions, deficit irrigation practices seem to be acceptable relatively to processing tomato yield aspects and Ky could be promoted as a useful indicator for irrigation in water deficit conditions.

关键词： Tomato deficit irrigation partial root-zone drying WUE Ky.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Experiments on the Speed of Light

引用

Journal of Applied Mathematics and Physics 2019年第5期7卷 1240-1249页

作者： José R. Croca Rui Moreira Mário gatta Paulo Castro Center for Philosophy of Sciences of the University of Lisbon (CFCUL) Lisbon Portugal Department of Physics Faculty of Sciences University of Lisbon Lisbon Portugal CINAV and Escola Naval (Portuguese Naval Academy) Lisbon Portugal

Many experiments concerning the determination of the speed of light have been proposed and done. Here two important experiments, Michelson-Morley and Sagnac, will be discussed. A linear moving variation of Michelson-M... 详细信息

关键词： Speed of Light Michelson-Morley Experiment Sagnac Experiment One-Arm Linear Moving Michelson-Morley and One-Beam Sagnac Interferometer Variants

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Music in DNA: From Williams Syndrome to Musical Genes

引用

Open Journal of Genetics 2015年第1期5卷 12-26页

作者： Corrada Di Rosa Filippo Cieri Ivana Antonucci Liborio Stuppia Valentina gatta Department of Psychological Humanities and Territorial Sciences School of Medicine and Life Sciences G. d’Annunzio University Chieti-Pescara Chieti Italy

Williams syndrome (WS) is a genetic disorder caused by a heterozygous contiguous gene deletion on chromosome 7q11.23. Clinical features of the disease include low IQ and deficit in some cog- nitive domains, and the presence of relatively strong abilities in social drive, face processing, language, and musical skills. The presence of a strong predisposition to the development of musicality in individuals affected by WS leads us to suppose that some genes deleted in this syndrome are somehow involved in the evolution of this ability, and that these genes could act in normal conditions as “suppressors of music ability”. To test this hypothesis, we carried out an “in silico” analysis by using the Ingenuity Pathway Analysis (IPA) software to identify the interaction between genes mapped in the WS critical region and genes previously related to musical ability by literature data. This approach allowed us to identify 3 networks of interaction, involving AVPR1A, NCF1, UNC5C and LAT2 in the first network, STX1A and SLC6A4 in the second one and only WS related genes in the last one. Among these associations, the one involving STX1A and SLC6A4 suggested a possible mechanism of interaction was based on the influence played by STX1A deletion on the serotonin levels through a decrease of SLC6A4 activity.

关键词： Williams Syndrome Music Ability Serotonin

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：