检索结果-南通市图书馆

Vascular endothelial growth factor:a double-edged sword in the development of white matter lesions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第1期20卷 191-192页

作者： Narek Manukjan Daniel Fulton Zubair Ahmed WMatthijs Blankesteijn sébastien Foulquier Department of Pharmacology and Toxicology Maastricht UniversityMaastrichtThe Netherlands CARIM-school for Cardiovascular Diseases Maastricht UniversityMaastrichtThe Netherlands Neuroscience and Ophthalmology Institute of Inflammation and AgeingUniversity of BirminghamEdgbastonBirminghamUK Centre for Trauma sciences Research University of BirminghamEdgbastonBirminghamUK MHeNs-school for Mental Health and Neuroscience Maastricht UniversityMaastrichtThe Netherlands Department of Neurology Maastricht University Medical CenterMaastrichtThe Netherlands

As the population ages,the burden of age-related diseases becomes ***,over 55 million people suffer from dementia worldwide,with Alzheimer’s disease being the most common ***,it is becoming clearer that underlying vascular pathology such as cerebral small vessel disease(csVD)may be a more detrimental cause for dementia(Cuadrado-Godia et al.,2018).It is estimated that 10%-30%of the elderly population and 35%-90%of all dementia patients exhibit signs of *** term csVD refers to pathology affecting the small vessels of the brain,which can lead to lacunar cerebral infarcts,enlarged perivascular spaces,and cortical hemorrhages(Cuadrado-Godia et al.,2018).CsVD is often associated with cognitive decline,gait problems,and dementia(Cuadrado-Godia et al.,2018).

关键词： pathology becoming white

Dissociation behavior of “dry water” C_3H_8 hydrate below ice point:Effect of phase state of unreacted residual water on a mechanism of gas hydrates dissociation

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2015年第3期24卷 309-314页

作者： andrey O Drachuk Vladimir P Melnikov Nadezhda s Molokitina Anatoliy N Nesterov Lev s Podenko Aleksey M Reshetnikov andrey Yu Manakov Institute of Earth Cryosphere SB RAS625026Malygin str.86TyumenRussian Federation Tyumen state Oil and Gas University 625000Volodarsky str.38TyumenRussian Federation Nikolaev Institute of Inorganic Chemistry SB RAS630090Lavrentiev av.3NovosibirskRussian Federation

The results on a dissociation behavior of propane hydrates prepared from ＂dry water＂ and contained unreacted residual water in the form of ice inclusions or supercooled liquid water（water solution of gas） were presented for temperatures below 273 *** temperature ramping or pressure release method was used for the dissociation of propane hydrate *** was found that the mechanism of gas hydrate dissociation at temperatures below 273 K depended on the phase state of unreacted water in the hydrate *** hydrates dissociated into ice and gas if the ice inclusions were in the hydrate *** samples of propane hydrates with inclusions of unreacted supercooled water only（without ice inclusions） dissociated into supercooled water and gas below the pressure of the supercooled water-hydrate-gas metastable equilibrium.

关键词： gas hydrates dry water supercooled liquid water ice hydrate dissociation

Gold Determination by Electrothermal Atomic Absorption spectrometry After Preconcentration Using Natural Deep Eutectic solvent Based on Menthol and Camphor

在线全文

学校读者我要写书评

暂无评论

Journal of Analysis and Testing 2023年第4期7卷 435-443页

作者： Valeriia Maksimova Varvara Lapina Leonid Martynov andrey shishov Olga Mokhodoeva Vernadsky Institute of Geochemistry and Analytical Chemistry Russian Academy of SciencesMoscow 119991Russian Federation Lomonosov Institute of Fine Chemical Technologies MIREA-Russian Technological UniversityMoscow 119454Russian Federation Department of Analytical Chemistry Institute of ChemistrySaint-Petersburg State UniversitySt.Petersburg 199034Russian Federation

A novel analytical procedure for the determination of gold by electrothermal atomic absorption spectrometry combined with selective liquid-liquid extraction by natural deep eutectic solvents(NADEss)is *** extraction ability of the NADEss prepared using menthol,thymol and camphor toward gold in hydrochloric acid solutions was *** extraction efficiency was improved by optimizing the parameters including the composition of the NADEs s,the volume ratio of organic and aqueous phases,kinetics,and acidity of the *** determination of gold was carried out by electrothermal atomic absorption spectrometry directly in the NADEs s phase dissolved in isopropyl *** extraction recovery of gold from 1 mol/L HCl with the NADEss based on menthol and camphor mixed in a molar ratio 1:1 was 99.7%at an enrichment factor of *** limits of detection and quantification of the proposed procedure were 1μg/L and 3.3μg/L,respectively,with a relative standard deviation of less than 5%.The developed procedure was applied for determination of gold in the certified reference material of ore,environmental and waste waters.

关键词： Gold Liquid-liquid extraction Menthol/camphor Natural deep eutectic solvents(NADEss) Electrothermal atomic absorption spectrometry(ETAAs)

, Optimization studies on synthesis of TKX-50

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 2017年第1期35卷 98-102页

作者： Yulia D. Golenko Maxim A. Topchiy andrey F. Asachenko Mikhail s. Nechaev Dmitriy V. Pleshakov A. V. Topchiev Institute of Petrochemical synthesis Russian Academy of Sciences Moscow 119991 Russian Federation Mendeleyev University Miusskaya sq. 9 Moscow 125047 Russian Federation

A systematic study of TKX-50 and ABTOX synthesis using both Klap6tke and Tselinskii modified procedures is described. The influence of temperature, moisture, acid amount and nature on the most critical synthesis step - diazidoglyoxime cyclization is shown. Experimental results show that presence of moisture in reaction mixture leads to product yield decreasing. The reaction temperature is another key parameter affecting product yield. High reaction temperature shows negative influence on the product yield in Klap6tke method. In Tselinskii procedure the yield of product grows with the reaction temperature increasing. For Klap6tke one-pot method, combination of N-methyl-2-pyrrolidone with 1,4-dioxane is the best solvent, whereas Tselinskii one-pot procedure gives high yield of product when combination of toluene with 0.5 equiv, of 1,8-diazabicyclo[5.4.0]undec-7-ene （DBU） is used. Us- ing optimized conditions one-pot five-step synthesis of TKX-50 starting from glyoxime is successfully performed and scaled up to 50 g.

关键词： TKX-50 ABTOX energetic salts tetrazoles solvent effects

snsi nanocrystals of zinc-blende structure in a si matrix

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2015年第12期8卷 3905-3911页

作者： Alexander Tonkikht andrey Klavsyuk Nikolay Zakharov Alexander saletsky Peter Werner Max Planck Institute of Microstructure Physics Halle(Saale) 06120 Germany Faculty of Physics Moscow State University Moscow 119991 Russian Federation

A zinc-blende （sphalerite） crystallographic structure of snsi nanocrystals generated by molecular-beam epitaxy is observed by electron microscopy techniques in a si matrix. Ab initio density-functional modeling reveals a stabilizing effect of the si matrix, which results in the lowest formation enthalpy of snsi nanocrystals having the unexpected zinc-blende structure. such nanocrystals could be applied in si photonics to function as non-centrosymmetric media for the nonlinear optical process of second harmonic generation.

关键词： epitaxy density functional theory zinc-blende si-sn alloy

Polarity,intramolecular charge transfer,and hydrogen bond comediated solvent effects on the optical properties of graphene quantum dots

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2023年第1期16卷 45-52页

作者： Yalei Hu Christof Neumann Lena scholtz andrey Turchanin Ute Resch-Genger siegfried Eigler Institute of Chemistry and Biochemistry Freie Universität BerlinTakustraße 314195 BerlinGermany Institute of Physical Chemistry and Abbe Center of Photonics Friedrich Schiller University JenaLessingstraße 1007743 JenaGermany Federal Institute for Materials Research and Testing(BAM) Division BiophotonicsRichard Willstätter Straße 1112489 BerlinGermany

Graphene quantum dots(GQDs)have attracted increasing attention due to their favorable optical properties and have been widely used,e.g.,in the biomedical ***,the properties related to the chemical structure of GQDs,resulting in solventdependent optical properties,still remain ***,we present the synthesis of long-wavelength emitting GQDs with a size of about 3.6 nm via a solvothermal method using oxo-functionalized graphene(oxo-G)and p-phenylenediamine as precursors and their structural and surface chemical analysis by transmission electron and atomic force microscopy(TEM;AFM)as well as Fourier-transform infrared,Raman,and X-ray photoelectron spectroscopy(FTIR;Raman;XPs).subsequently,the influence of solvent polarity and proticity on the optical properties of the as-prepared GQDs bearing–OH,–NH_(2),–COOH and pyridine surface groups was *** on the results of the absorption and fluorescence(FL)studies,a possible luminescence mechanism is *** observed solvent-induced changes in the spectral position of the FL maximum,FL quantum yield,and FL decay kinetics in protic and aprotic solvents of low and high polarity are ascribed to a combination of polarity effects,intramolecular charge transfer(ICT)processes,and hydrogen ***,the potential of GQDs for the optical sensing of trace amount of water was *** results of our systematic spectroscopic study will promote the rational design of GQDs and shed more light on the FL mechanism of carbon-based fluorescent nanomaterials.

关键词： graphene quantum dots(GQDs) polarity intramolecular charge transfer(ICT) hydrogen bond optical properties

submonolayer Eu superstructures—A class of 2D magnets

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2023年第1期16卷 1500-1506页

作者： Dmitry V.Averyanov Ivan s.sokolov Alexander N.Taldenkov Oleg E.Parfenov andrey M.Tokmachev Vyacheslav G.storchak National Research Center“Kurchatov Institute” Kurchatov Sq.1Moscow 123182Russia

Two-dimensional(2D)magnetic materials promise unconventional properties and quantum phases as well as advances in ultracompact *** of 2D magnets often reaches a single monolayer but in general can go beyond this limit,as demonstrated by 2D magnetism of submonolayer Eu superstructures coupled with *** question is whether the submonolayer magnetism constitutes a general ***,we demonstrate that regular Eu lattices form a class of 2D magnets displaying various structures,stoichiometries,and chemical *** synthesized and studied a set of Eu superstructures on Ge(001).Their magnetic properties are consistent with the emergence of a magnetic order such as ferro-or *** particular,control over the magnetic transition temperature by weak magnetic fields indicates the 2D nature of the *** together,Eu/Ge and Eu/si superstructures seed a nucleus of the research area addressing the emergence of magnetism in submonolayer chemical species.

关键词： two-dimensional(2D)magnetism submonolayer superstructure surface reconstruction germanium

Irisin/BDNF signaling in the muscle-brain axis and circadian system: A review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Journal of Biomedical Research 2024年第1期38卷 1-16页

作者： Alexey N.Inyushkin Vitalii s.Poletaev Elena M.Inyushkina Igor s.Kalberdin andrey A.Inyushkin Department of Human&Animal Physiology Samara National Research UniversitySamara 443011Russia.

In mammals,the timing of physiological,biochemical and behavioral processes over a 24-h period is controlled by circadian *** entrain the master clock located in the suprachiasmatic nucleus of the hypothalamus to a precise 24-h rhythm,environmental zeitgebers are used by the circadian *** is done primarily by signals from the retina via the retinohypothalamic tract,but other cues like exercise,feeding,temperature,anxiety,and social events have also been shown to act as non-photic *** recently identified myokine irisin is proposed to serve as an entraining non-photic signal of *** is a product of cleavage and modification from its precursor membrane fibronectin typeⅢdomain-containing protein 5(FNDC5)in response to *** from well-known peripheral effects,such as inducing the"browning"of white adipocytes,irisin can penetrate the blood-brain barrier and display the effects on the *** data suggest that FNDC5/irisin mediates the positive effects of physical activity on brain *** several brain areas,irisin induces the production of brain-derived neurotrophic factor(BDNF).In the master clock,a significant role in gating photic stimuli in the retinohypothalamic synapse for BDNF is ***,the brain receptor for irisin remains *** the current review,the interactions of physical activity and the irisin/BDNF axis with the circadian system are reconceptualized.

关键词： irisin brain-derived neurotrophic factor peroxisome proliferator-activated receptorγcoactivator 1α circadian rhythm circadian system muscle-brain axis

Effective properties of a porous inhomogeneously polarized by direction piezoceramic material with full metalized pore boundaries:finite element analysis

在线全文

学校读者我要写书评

暂无评论

Journal of Advanced Dielectrics 2020年第5期10卷 1-10页

作者： andrey Nasedkin Mohamed Elsayed Nassar Institnute of Mathematics Mechanics and Computer Science Southem Federal University Miltchakova Street 8aRostov on Don 344090Russia Department of Physics and Engineering Mathematics Faculty of Electronic Engineering Menoufia University 32952 MenoufEgypt

This paper concerns the homogenization problems for porous piezocomposites with infinitely thin metalized pore *** determine the effective properties,we used the effective moduli method and the finite element approaches,realized in the ANsYs *** a simple model of the representative volume,we applied a unit cell of porous piezoceramic material in the form of a cube with one spherical *** modeled metallization by introducing an additional layer of material with very large permittivity coefficients along the pore *** we simulated the nonuniform polarization field around the *** taking this effect into account,we previously solved the electrostatic problem for a porous dielectric material with the same geometric *** this problem,we obtained the polarization field in the porous piezomaterial;after that,we modified the material properties of the finite elements from dielectric to piezoelectric with element coordinate systems whose corresponding axes rotated along the polarization *** a result,we obtained the porous unit cell of an inhomogeneously polarized piezoceramic *** the solutions of these homogenization problems,we observed that the examined porous piezoceramics composite with metalized pore boundaries has more extensive effective transverse and shear piezomoduli,and effective dielectric constants compared to the conventional porous *** analysis also showed that the effect of the polarization field inhomogeneity is insignificant on the ordinary porous piezoceramics;however,it is more significant on the porous piezoceramics with metalized pore surfaces.

关键词： Piezoelectricity porous piezoceranics metalized micropore nonuniform polarization transverse piezoelectic modulus homogerization problem effective modulus finite element method