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Endocr.ne cor.elates of mate choice and pr.miscuity in females of a socially monogamous avian mating system with alter.ative male r.pr.ductive phenotypes

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Cur.ent Zoology 2014年第6期60卷 804-815页

作者： Huber. SCHWABL Willow r. LINDSAY Douglas G. barron Michael S. WEBSTEr School of Biological Sciences and Center.for.r.pr.ductive Biology Washington State University Pullman WA 99164-4236 USA Depar.ment of Depar.ment of Biological and Envir.nmental Sciences Goteborg University Box 463405 30 Goteborg Sweden Depar.ment of Psychology University of South Florida Tampa FL 33620-7200 USA Depar.ment of Neur.biology and Behavior and Comell Laboratory for Ornithology Comell University Ithaca NY 14850 USA

While our.under.tanding of male r.pr.ductive str.tegies is infor.ed by extensive investigations into endocr.ne mechanisms, the pr.ximate mechanisms by which females compete for.mates and adjust r.pr.duction to social envir.nment r.mains enigmatic. We set out to uncover.endocr.ne cor.elates of mate choice, social envir.nment, and r.pr.ductive investment in female r.d-backed fair.-wr.ns Malur.s melanocephalus. In this socially monogamous, yet highly sexually pr.miscuous species, females exper.ence discr.te var.ation in the phenotype of their.mates, which var. in both plumage signals and level of pater.al car., and in the composition of their.br.eding gr.ups, which consist of either.the pair.alone or.with an additional cooper.tive auxiliar.; fe- male investment var.es accor.ing to these social par.meter.. We found that andr.gen, estr.gen, and glucor.icoid levels var.ed with r.pr.ductive stage, with highest andr.gen and estr.gen concentr.tions dur.ng nest constr.ction and highest cor.icoster.ne concentr.tions dur.ng the pr.-br.eding stage. These stage-dependent patter.s did not var. with male phenotype or.auxiliar. pr.sence, though andr.gen levels dur.ng pr.-br.eding mate selection wer. lower.in females obtaining r.d/black mates than those obtaining br.wn mates. We found no evidence that andr.gen, estr.gen, or.cor.icoster.ne levels dur.ng the fer.ile per.od wer. r.- lated to extr.-pair.young （EPY） fr.quency. This study demonstr.tes clear.changes in ster.id levels with r.pr.ductive stage, though it found little suppor. for.var.ation with social envir.nment. We suggest hor.onal r.sponsiveness to social factor. may be physiologically constr.ined in ways that ar. bypassed thr.ugh exogenous hor.one manipulations.

关键词： Andr.gen Estr.gen Glucocor.icoid Mate choice Pr.miscuity Alter.ative phenotypes

Super.hir.l near.fields detect vir.s str.ctur.

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Light(Science & Applications) 2020年第1期9卷 103-112页

作者： Tar.n Kakkar.Chantal Keijzer.Mar.on r.dier.Tatyana Bukhar.va Michael Taliansky andrew J.Love Joel J.Milner.Affar.S.Kar.mullah Laur.nce D.barron Nikolaj Gadegaar. Adr.an J.Lapthor. Malcolm Kadodwala School of Chemistr. Joseph Black BuildingUniversity of GlasgowGlasgow G128QQUK Institute of Molecular Cell and Systems Biology and School of Life SciencesUniversity of GlasgowG128QQ GlasgowUK James Hutton Inst Cell&Mol SciDundee DD25DAUK Shemyakin-Ovchinnikov Institute of Bioor.anic Chemistr. r.S Moscow 117997Russia School of Engineer.ng Rankine BuildingUniversity of GlasgowGlasgow G128LTUK

Optical spectr.scopy can be used to quickly char.cter.se the str.ctur.l pr.per.ies of individual ***,it cannot be applied to biological assemblies because light is gener.lly blind to the spatial distr.bution of the component *** insensitivity ar.ses fr.m the mismatch in length scales between the assemblies(a few tens of nm)and the wavelength of light r.quir.d to excite chr.mophor.s(≥150 nm).Consequently,with conventional spectr.scopy,or.er.d assemblies,such as the icosahedr.l capsids of vir.ses,appear.to be indistinguishable isotr.pic spher.cal *** limits potential r.utes to r.pid high-thr.ughput por.able detection appr.pr.ate for.point-of-car. ***,we demonstr.te that chir.l electr.magnetic(EM)near.fields,which have both enhanced chir.l asymmetr.(r.fer.ed to as super.hir.lity)and subwavelength spatial localisation(∼10 nm),can detect the icosahedr.l str.ctur. of vir.s ***,they can detect both the pr.sence and r.lative or.entation of a bound vir.s *** illustr.te the potential uses of the exquisite str.ctur.l sensitivity of subwavelength super.hir.l fields,we have used them to successfully detect vir.s par.icles in the complex milieu of blood ser.m.

关键词： chir.l detect fields

Autolysosomal acidification impair.ent as a mediator.for.TNFr. induced neur.nal necr.ptosis in Alzheimer.s disease

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Neur.l r.gener.tion r.sear.h 2024年第9期19卷 1869-1870页

作者： Evr.diki Asimakidou r.char. r.ynolds Anna M.barron Chih Hung Lo Depar.ment of Clinical Neur.sciences University of CambridgeCambridgeUK Depar.ment of Br.in Sciences Faculty of MedicineImperial College LondonLondonUK Lee Kong Chian School of Medicine Nanyang Technological UniversitySingaporeSingapore

Neur.nal necr.ptosis-an emer.ing for. of r.gulated cell death associated with neur.inflammator. signaling:Alzheimer.s disease(AD)is char.cter.zed by the pr.sence of extr.cellular.amyloid-β(Aβ)plaques and intr.cellular.tau neur.fibr.llar. tangles as well as pr.gr.ssive neur.nal *** evidence has suggested that pr.longed neur.inflammation with incr.ased levels of cytokines,ar.sing fr.m neur.nal injur.,innate immune r.sponses fr.m glial cells,and per.pher.l inflammation,leads to neur.nal death and AD pr.gr.ssion.

关键词： Alzheimer death tau Aβ

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Multiple myeloma sur.ival in New South Wales, Austr.lia, by tr.atment er. to 2020

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Cancer.Biology & Medicine 2024年第8期21卷 703-711页

作者： Eleonor. Feletto Qingwei Luo Anna Kelly Mar.anne Weber.David Goldsbur. Kather.ne barron Kar.n Canfell Xue Qin Yu The Daffodil Centr. The University of SydneyA Joint Venture with Cancer Council NSWSydney NSW 2006Australia

Objective: Austr.lia has r.latively high multiple myeloma(MM) incidence and mor.ality r.tes. Advancements in MM tr.atment over.r.cent decades have dr.ven impr.vements in MM sur.ival in high-income countr.es;however. r.por.ing in Austr.lia is limited. We investigated tempor.l tr.nds in population-wide MM sur.ival acr.ss 3 per.ods of tr.atment advancements in New South Wales(NSW), ***: Individuals with an MM diagnosis in the NSW Cancer.r.gistr. between 1985 and 2015 with vital follow-up to 2020, wer. categor.zed into 3 pr.viously defined tr.atment er.s accor.ing to their.diagnosis date(1985±1995, chemother.py only;1996±2007, autologous stem cell tr.nsplantation;and 2008±2015, novel agents including pr.teasome inhibitor. and immunomodulator. dr.gs). Both r.lative sur.ival and cause-specific sur.ival accor.ing to Fine and Gr.y's competing r.sks cumulative incidence function wer. calculated by tr.atment er. and age at ***: Over.ll, 11,591 individuals wer. included in the study, with a median age of 70 year. at diagnosis. Five-year.r.lative sur.ival impr.ved over.the 36-year.1985±2020) study per.od(31.0% in 1985±1995;41.9% in 1996±2007;and 56.1% in 2008±2015). For.individuals diagnosed befor. 70 year. of age, the 5-year.r.lative sur.ival near.y doubled, fr.m 36.5% in 1985±1995 to 68.5% in 2008±2015. Impr.vements for.those > 70 year. of age wer. less pr.nounced between 1985±1995 and 1996±2007;however. significant impr.vements wer. obser.ed for.those diagnosed in 2008±2015. Similar.over.ll and age-specific patter.s wer. obser.ed for.causespecific sur.ival. After.adjustment for.gender.and age at diagnosis, tr.atment er. was str.ngly associated with both r.lative and cause-specific sur.ival(P r.ival of individuals with MM is impr.ving in Austr.lia with tr.atment advances. However. older.age gr.ups continue to exper.ence poor.sur.ival outcomes with only modest impr.vements over.time. Given the incr.asing pr.valence of MM in

关键词： Multiple myeloma cancer.epidemiology sur.ival analysis competing r.sk analysis Austr.lia

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Inter.al Vibr.tion and Synchr.nization of Four.Coupled Self-Excited Elastic Beams

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Open Jour.al of Applied Sciences 2016年第8期6卷 501-513页

作者： Miguel A. barron Depar.amento de Mater.ales Universidad Autonoma Metropolitana Azcapotzalco Ciudad de Mexico Mexico

The vibr.tion behavior.and the synchr.nization between some inter.al points of four.coupled self-excited beams ar. numer.cally studied. Coupling thr.ugh the r.ot of the beams is consider.d. The tr.nsver.e displacements of the inter.al points and the beam tips ar. monitor.d, and the power.spectr. of the r.sulting time ser.es ar. employed to deter.ine the oscillation fr.quencies. The synchr.nization between beams is analyzed using phase por.r.its and cor.elation coefficients. Numer.cal r.sults show multiple fr.quencies in the vibr.tion patter., and complex patter.s of synchr.nization between pair. of beams.

关键词： Coupled Beams Self-Excited Beams Spatially Extended Oscillator. Synchr.nization Vibr.tion Behavior

微型计算机在监控仪表、数据采集、分析和控制中的应用

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遥测遥控 1986年第1期 44-52页

作者： r. barron 禹克林

微处理机特别适用于工业生产过程中数据收集、过程控制和重要参数测量方面的自动化。本文介绍微型机的几个应用例。其中,开发和研究工作是利用由Z80微处理机和附加电路板所组成的微型计算机而进行的。所介绍的是在数据采集、过程控制和... 详细信息

微处理机特别适用于工业生产过程中数据收集、过程控制和重要参数测量方面的自动化。本文介绍微型机的几个应用例。其中,开发和研究工作是利用由Z80微处理机和附加电路板所组成的微型计算机而进行的。所介绍的是在数据采集、过程控制和变量测量方面的一些应用。

关键词：微型计算机电路板个人电脑电子数字计算机线路板计算机程序方程方程式微处理机数据处理数据采集仪表

Numer.cal Simulation of an Ar.on Stir.ed Ladle with Top and Bottom Injection

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Open Jour.al of Applied Sciences 2016年第13期6卷 860-867页

作者： Sofia Tor.es Miguel A. barron Depar.amento de Mater.ales Universidad Autonoma Metropolitana Azcapotzalco Mexico City Mexico

The stir.ing of a molten steel ladle with ar.on injection thr.ugh a top submer.ed lance and a bottom nozzle is numer.cally studied her. thr.ugh Computational Fluid Dynamics (CFD) simulations. Thr.e lance submer.ence depths and thr.e injection velocities ar. consider.d in the CFD numer.cal exper.ments. The tur.ulent dissipation r.te is employed to char.cter.ze the stir.ing phenomenon. The mixing times ar. deter.ined fr.m the gas flow r.te, ladle geometr. and bath depth using an empir.cal cor.elation.

关键词： Ar.on Injection CFD Simulations Gas Stir.ing Mixing Time Molten Steel Ladle Stir.ing Efficiency

Numer.cal Analysis of Slag Splashing in a Steelmaking Conver.er

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Computer.Technology and Application 2011年第10期2卷 828-834页

作者： Miguel barron Isaias Hiler.o Depar.amento de Mater.ales Universidad Autonoma Metropolitana Azcapotzalco Av. San Pablo 180 Col. Reynosa-TamaulipasMexico D.F. 02200 Mexico

Some var.ables that influence the slag splashing phenomenon in an oxygen steelmaking conver.er.ar. numer.cally analyzed in this wor.. The effect of lance height, jet velocity, jet exit angle and slag viscosity on the washing and ejection mechanisms of slag splashing is studied employing tr.nsient two-dimensional computational fluid dynamics simulations. A par.meter.her. called aver.ge slag volume fr.ction is pr.posed for.the quantitative evaluation of the slag splashing efficiency. Besides, a qualitative compar.son is made between the computational fluid dynamics r.sults and physical model r.sults fr.m liter.tur..

关键词： Computational fluid dynamics basic oxygen fur.ace oxygen steelmaking r.fr.ctor. lining slag splashing

Effect of inductively coupled plasma sur.ace tr.atment on silica gel and mesopor.us MCM-41 par.icles

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Plasma Science and Technology 2018年第6期20卷 104-113页

作者： J A JUAr.Z-MOr.NO U CHACON-Ar.AEZ J barron-ZAMBr.NO C CAr.Er.-FIGUEIr.S P QUINTANA-OWEN W TALAVEr.-PECH Y PEr.Z-PADILLA A AVILA-Or.EGA facultad de ingenier.a química-uady periférico norte kilómetro 33.5col.chuburna de hidalgo inn C.P. 97203 Mérida Yucatan México centr. de investigación y de estudios avanzados del ipn-unidad mér.da km.6 antigua car.eter. a pr.gr.so apdo. Postal 73 Cordemex 97310 Méfida Yucatán México

Silica gel and MCM-41 synthesized mesopor.us mater.als wer. tr.ated with either.oxygen（O_2）,hexamethyldisiloxane（HMDSO） and or.anic vapor. like ethanol（Et OH）,and acr.lonitr.le（AN）inductive *** r.diofr.quency power.for.the modification was fixed to 120 W and30 min,assur.ng a high degr.e of or.anic ionization ener.y in the *** sur.ace pr.per.ies wer. studied by infr.r.d spectr.scopy（FTIr.,scanning electr.n micr.scopy,x-r.y photoelectr.n spectr.scopy and dynamic light scatter.ng technique was used for.char.cter.zing size *** the silica and MCM-41 par.icles wer. modified by AN and HMDSO plasma gases,the sur.ace mor.hology of the par.icles was changed,pr.senting another.color.size or.*** contr.st,the tr.atments of oxygen and Et OH did not affect the sur.ace mor.hology of both par.icles,but incr.ased the oxygen content at the sur.ace bigger.than the AN and HMDSO plasma *** this study,we investigated the influence of differ.nt plasma tr.atments on changes in mor.hology and the chemical composition of the modified par.icles which r.nder.them a possible new adsor.ent for.utilization in sor.tive extr.ction techniques for.polar.compounds.

关键词： silica MCM-41 nanopar.icles plasma tr.atment

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