检索结果-南通市图书馆

The role of mon.amin.s in.modulatin. behavior

Curren. Zoology 2016年第3期62卷 253-255页

作者： John.G. SWALLOW andrew n. bubak Jaime L. GRACE Guest Editors Departmen. of In.egrative Biology University of Colorado Denver Denver CO USA n.uroscien.e Program University of Colorado Denver Anschutz Medical Campus Aurora CO USA Departmen. of Biology Bradley University Peoria IL USA

Un.erstan.in. the mechan.sms un.erlyin. complex behaviors re- quires a comprehen.ive in.estigation.of the n.urobiological factors that regulate an. modulate their expression. Mon.amin.s, such as seroton.n. dopamin., an. n.radren.lin., serve a variety of essen.ial physiological roles in.modulatin. an.mal behavior. Furthermore, the evolution.ry con.ervation.of these amin.rgic systems span. across both vertebrates an. in.ertebrates, havin. comparable effects in.such diverse processes as learn.n. an. memory, aggression. matin. behaviors an. reproduction. stress respon.es, locomotion. an. col- lective social behaviors （Dishman.1997; Libersat an. Pflueger 2004; Kamhi an. Tran.ello 2013; bubak et al. 2014a; De Boer et al. 2015）. Outstan.in. research is curren.ly bein. con.ucted in.this field, un.overin. remarkable similarities in.n.ural circuitries even.amon. highly divergen. taxa, such as Drosophila an. human.. In.estigatin. the n.ural mechan.sms in.olved in.the mon.amin.rglc modulation.of behavior across a variety of taxon.mically distan. species can.provide researchers with a better un.erstan.in. of the origin. an. fun.tion. of these systems. The goal of this special issue is to provide a ven.e in.which colleagues studyin. similar question. across highly divergen. an.mal systems can.presen. their recen. an. groun.breakin. work in.this excitin. area of biology. We hope this collection.of papers will en.ourage an. stimulate a dialogue on.the similarities of mon.amin.rgic fun.tion.in.a wide variety of an.mals an. ultimately promote future comparative approaches when.in.es- tigatin. behavioral modulation.

关键词：单胺类神经递质动物行为生物学因素无脊椎动物神经系统去甲肾上腺素神经机制 5-羟色胺

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Assessmen. strategies an. fightin. pattern. in.an.mal con.ests： a role for seroton.n.

引用

Curren. Zoology 2016年第3期62卷 257-263页

作者： andrew n. bubak Alison.R. GERKEn.Michael J. WATT Jamie D, COSTABILE Ken.eth J. REn.ER John.G. SWALLOW In.egrative Biology University of Colorado-Denver Denver CO 80217-3364 USA Molecular Gen.tics an. Microbiology University of Florida Gainesville FL 32611 USA Cen.er for Brain.an. Behavior Research Basic Biomedical Sciences University of South Dakota Vermillion SD 57069 USA Biology Departmen. University of South Dakota Vermillion SD 57069 USA

Accurate assessmen. of the probability of success in.an.aggressive con.ron.ation.with a con.pecific is critical to the survival an. fitn.ss of the in.ividuals. Various game theory models have examin.d these assessmen. strategies un.er the assumption.that con.ests should favor the an.mal with the greater resource-holdin. poten.ial （RHP）, body size typically bein. the proxy. Mutual assessmen. asserts that an.in.ividual can.assess their own.RHP relative to their oppon.n., allowin. the in.erior an.mal the chan.e to flee before in.urrin. un.ecessary costs. The model of self-determin.d persisten.e, however, assumes that an.in.ividual will fight to a set person.l threshold, in.epen.- en. of their oppon.n.＇s RHP. Both models have been.repeatedly tested usin. size as a proxy for RHP, with n.ither receivin. un.mbiguous support. Here we presen. both morphological an. n.uro- physiological data from size-matched an. mismatched stalk-eyed fly fights. We discovered differ- in. fightin. strategies between.win.ers an. losers. Win.ers readily escalated en.oun.ers to higher in.en.ity an. physical con.act an. en.aged in.less low-in.en.ity, posturin. behaviors compared with losers. Although these fightin. strategies were largely in.epen.en. of size, they were associ- ated with elevated levels of 5-HT. Un.erstan.in. the n.urophysiological factors respon.ible for mediatin. the motivation.l state of oppon.n.s could help resolve the in.on.isten.ies seen.in.cur- ren. game theory models. Therefore, we con.en. that curren. studies usin. on.y size as a proxy for RHP may be in.dequate in.determin.n. the in.ricacies of fightin. ability an. that future studies in.estigatin. assessmen. strategies an. con.est outcome should in.lude n.urophysiological data.

关键词： aggression assessmen. fightin. strategies seroton.n mon.amin.s resource-holdin. poten.ial.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The organ.zation.of societal con.licts by pavemen. an.s Tetramorium caespitum： an.agen.-based model of amin.-mediated decision.makin.

引用

Curren. Zoology 2016年第3期62卷 277-284页

作者： Kevin.M. HOOVER andrew n. bubak Isaac J. LAW Jazmin. D. W. YAEGER Ken.eth J. REn.ER John.G. SWALLOW Michael J. GREEn. Departmen. of In.egrative Biology University of Colorado Denver Denver CO 80217-3364 USA n.uroscien.e Program University of Colorado Anschutz Medical Campus Aurora CO 80045 USA Departmen. of Biology University of South Dakota Vermillion South Dakota 57069 USA

An. colon.es self-organ.ze to solve complex problems despite the simplicity of an.in.ividual an.＇s brain. Pavemen. an. Tetramorium caespitum colon.es must solve the problem of defen.in. the ter- ritory that they patrol in.search of en.rgetically rich forage. When.members of 2 colon.es ran.omly in.eract at the territory boun.ary a decision.to fight occurs when. 1） there is a mismatch in.n.st- mate recogn.tion.cues an. 2） each an. has a recen. history of high in.eraction.rates with n.stmate an.s. In.tead of fightin., some an.s will decide to recruit more workers from the n.st to the fightin. location. an. in.this way a positive feedback mediates the developmen. of colon. wide wars. In.an.s, the mon.amin.s seroton.n.（5-HT） an. octopamin. （OA） modulate man. behaviors associated with colon. organ.zation.an. in.particular behaviors associated with n.stmate recogn.tion.an. ag- gression. In.this article, we develop an. explore an.agen.-based model that con.eptualizes how in. dividual chan.es in.brain.con.en.ration. of 5-HT an. OA, paired with a simple threshold-based de- cision.rule, can.lead to the developmen. of colon. wide warfare. Model simulation. do lead to the developmen. of warfare with 91% of an.s fightin. at the en. of 1 h. When.con.uctin. a sen.itivity an.lysis, we determin.d that un.ertain.y in.mon.amin. con.en.ration.sign.l decay in.luen.es the behavior of the model more than.un.ertain.y in.the decision.makin. rule or den.ity. We con.lude that pavemen. an. behavior is con.isten. with the detection.of in.eraction.rate through a sin.le timed in.erval rather than.in.egration.of multiple in.eraction..

关键词： agen.-based model aggressive behavior an.s decision.makin. mon.amin.s octopamin. seroton.n.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

n.urochemistry as a bridge between.morphology an. behavior： Perspectives on.aggression.in.in.ects

引用

Curren. Zoology 2014年第6期60卷 778-790页

作者： andrew n. bubak Jaime L. GRACE Michael J. WATT Ken.eth J. REn.ER John.G. SWALLOW n.uroscien.e Program University of Colorado-Denver Anschutz Medical Campus Aurora CO 80045 USA Departmen. of In.egrative Biology University of Colorado-Denver Denver CO 80217-3364 USA Cen.er for Brain.an. Behavior Research Basic Biomedical Sciences University of South Dakota Vermillion SD 57069 USA Departmen. of Biology University of South Dakota Vermillion SD 57069 USA

Aggression.is a common.behavioral trait shared in.man. an.mals, in.ludin. both vertebrates an. in.ertebrates. However, the type an. in.en.ity of agon.stic en.oun.ers an. displays can.vary widely both across an. within.species, resultin. in.complicated or subjective in.erpretation. that create difficulties in.developin. theoretical models that can.be widely applied. The n.ed to easily an. objectively iden.ify quan.ifiable behaviors an. their associated morphologies becomes especially importan. when.attemptin. to decipher the n.urological mechan.sms un.erlyin. this complex behavior. Mon.amin.s, n.uropeptides, an. pheromon.s have been.implicated as importan. n.uromodulators for agon.stic displays in.both in.ertebrates an. vertebrates. Ad- dition.lly, recen. breakthroughs in.in.ect research have revealed excitin. proximate mechan.sms importan. in.aggression.that may be broadly relevan., due to the relatively high con.ervation.of these n.urochemical systems across an.mal taxa. In.this review, we presen. the latest research demon.tratin. the importan.e of mon.amin.s, n.uropeptides, an. pheromon.s as n.uromodulators for aggression.across a variety of in.ect species. Addition.lly, we describe the stalk-eyed fly as a model system for studyin. aggres- sion. which in.egrates physiological, morphological, an. n.urochemical approaches in.explorin. detailed mechan.sms respon.ible for this common.yet complex behavior. We con.lude with our perspective on.the most promisin. lin.s of future research aimed at un.erstan.in. the proximate an. ultimate mechan.sms un.erlyin. aggressive behaviors .

关键词： Mon.amin.s Aggression In.ects Evolution.ry physiology Sexual Selection

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

n.cleoside modified mRn.-lipid n.n.particles as a n.w delivery platform for the repair of the in.ured spin.l cord

引用

n.ural Regen.ration.Research 2025年第8期20卷 2311-2312页

作者： Krisztián.Pajer Tamás Bellák An.al n.grádi Departmen. of An.tomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary

Spin.l cord in.ury an. treatmen. opportun.ties:The adult mammalian.spin.l cord has a very limited capacity for spon.an.ous regen.ration.due to various in.rin.ic molecular an. cellular *** the spin.l cord n.uron. have the capacity to regen.rate their axon.,the expression.of growth in.ibitory factors,lack or suppression.of proper guidan.e cues,an. profoun. in.lammatory respon.es do n.t permit successful regen.ration.Khyeam et al.,2021).

关键词： in.ured capacity modified

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Impacts of PI3K/protein.kin.se B pathway activation.in.reactive astrocytes: from detrimen.al effects to protective fun.tion.

引用

n.ural Regen.ration.Research 2025年第4期20卷 1031-1041页

作者： Ramón.Pérez-n.ñez María Fern.n.a Gon.ález An. María Avalos Lisette Leyton Cellular Commun.cation.Laboratory Programa de Biología Celular y MolecularCenter for Studies on ExerciseMetabolism and Cancer(CEMC)Instituto de Ciencias Biomédicas(ICBM)Facultad de MedicinaUniversidad de ChileSantiagoChile Advan.ed Cen.er for Chron.c Diseases(ACCDiS) Faculty of Chemical and Pharmaceutical Sciences&Faculty of MedicineUniversidad de ChileSantiagoChile In.tituto de Cien.ias Biomédicas Facultad de Ciencias de la SaludUniversidad Autónoma de ChileSantiagoChile

Astrocytes are the most abun.an. type of glial cell in.the cen.ral n.rvous *** in.ury an. in.lammation.astrocytes become reactive an. un.ergo morphological an. fun.tion.l *** on.their phen.typic classification.as A1 or A2,reactive astrocytes con.ribute to both n.urotoxic an. n.uroprotective respon.es,***,this bin.ry classification.does n.t fully capture the diversity of astrocyte respon.es observed across differen. diseases an. *** an.lysis has revealed that reactive astrocytes have a complex lan.scape of gen. expression.profiles,which emphasizes the heterogen.ous n.ture of their *** actively participate in.regulatin. cen.ral n.rvous system in.lammation.by in.eractin. with microglia an. other cell types,releasin. cytokin.s,an. in.luen.in. the immun. *** phosphoin.sitide 3-kin.se(PI3K)/protein.kin.se B(AKT)sign.lin. pathway is a cen.ral player in.astrocyte reactivity an. impacts various aspects of astrocyte behavior,as eviden.ed by in.silico,in.vitro,an. in.vivo *** astrocytes,in.lammatory cues trigger a cascade of molecular even.s,where n.clear factor-κB serves as a cen.ral mediator of the pro-in.lammatory ***,we review the heterogen.ity of reactive astrocytes an. the molecular mechan.sms un.erlyin. their *** highlight the in.olvemen. of various sign.lin. pathways that regulate astrocyte reactivity,in.ludin. the PI3K/AKT/mammalian.target of rapamycin.mTOR),αvβ3 in.egrin.PI3K/AKT/con.exin.43,an. n.tch/PI3K/AKT *** targetin. the in.ctivation.of the PI3K/AKT cellular sign.lin. pathway to con.rol reactive astrocytes an. preven. cen.ral n.rvous system damage,eviden.e suggests that activatin. this pathway could also yield ben.ficial *** dual fun.tion.of the PI3K/AKT pathway un.erscores its complexity in.astrocyte reactivity an. brain.fun.tion.*** review emphasizes the importan.e of employin. astrocyte-exclusive models to un.erst

关键词： in.lammation in.egrin. n.uroprotective n.urotoxic phosphatidylin.sitol 3-kin.se reactive astrocytes sign.l tran.duction Thy-1(CD90)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Sex differen.es in.agin. an. in.ured brain

引用

n.ural Regen.ration.Research 2025年第10期20卷 2901-2902页

作者： Jordan.n.Williamson.Yuan.Yan. Un.versity of Illin.is Urban.-Champaign Grainger College of EngineeringDepartment of BioengineeringUrbanaILUSA Carle Foun.ation.Hospital Stephenson Family Clinical Research InstituteClinical Imaging Research CenterUrbanaILUSA Un.versity of Illin.is Urban.-Champaign Beckman Institute for Advanced Science and TechnologyUrbanaILUSA n.rthwestern.Un.versity Department of Physical Therapy and Human Movement SciencesChicagoILUSA

Backgroun.:The prevalen.e,age of on.et,an. symptomatology of traumatic brain.in.ury,stroke,an. n.urodegen.rative diseases(such as Alzheimer’s disease(AD),Parkin.on.s disease,amyotrophic lateral sclerosis,an. Hun.in.ton.s disease)differ substan.ially between.males an. *** higher prevalen.e of these brain.disorders has been.attributed to females havin. a greater lon.evity compared with *** on. of the greatest risk factors of acquired brain.in.ury(such as stroke,traumatic brain.in.ury caused by fall)an. n.urodegen.rative disease is age.

关键词： Hun.in.ton prevalen.e traumatic

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Astrocytes, reactive astrogliosis, an. glial scar formation.in.traumatic brain.in.ury

引用

n.ural Regen.ration.Research 2025年第4期20卷 973-989页

作者： María Belén.Cieri Alberto Javier Ramos Laboratorio de n.uropatología Molecular IBCN UBA-CONICETFacultad de MedicinaUniversidad de Buenos AiresBuenos AiresArgentina

Traumatic brain.in.ury is a global health crisis,causin. sign.fican. death an. disability *** that follows traumatic brain.in.ury has serious con.equen.es for n.uron.l survival an. cogn.tive impairmen.s,with astrocytes in.olved in.this *** traumatic brain.in.ury,astrocytes rapidly become reactive,an. astrogliosis propagates from the in.ury core to distan. brain.*** astroglial protein. are down.egulated n.ar the traumatic brain.in.ury core,while pro-in.lammatory astroglial gen.s are *** altered gen. expression.is con.idered a pathological remodelin. of astrocytes that produces serious con.equen.es for n.uron.l survival an. cogn.tive *** addition.glial scar formed by reactive astrocytes is in.tially n.cessary to limit immun. cell in.iltration.but in.the lon. term impedes axon.l recon.ection.an. fun.tion.l *** therapeutic strategies for traumatic brain.in.ury are focused on.preven.in. acute ***,can.abin.ids,progesteron.,beta-blockers,an. cerebrolysin.demon.trate n.uroprotective ben.fits but most of them have n.t been.studied in.the con.ext of *** this review,we discuss the cell sign.lin. pathways activated in.reactive astrocytes followin. traumatic brain.in.ury an. we discuss some of the poten.ial n.w strategies aimed to modulate astroglial respon.es in.traumatic brain.in.ury,especially usin. cell-targeted strategies with miRn.s or ln.Rn.,viral vectors,an. repurposed drugs.

关键词： astrocyte glial scar in.ate immun.ty n.uroin.lammation stab in.ury Toll-like receptors

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A n.w Method of Syn.hesis of Azo Schiff Base Ligan.s with Azo an. Azomethin. Don.rs： Syn.hesis of n.4-Methoxyben.yliden.-2-（3-hydroxyphen.lazo）-5-hydroxyan.lin. an. Its n.ckel（Ⅱ） Complex

引用

Chin.se Journ.l of Chemistry 2007年第6期25卷 869-871页

作者： OFORKA, n. C. MKPEn.E, V. n. Departmen. of Pure an. In.ustrial Chemistry University of Port Harcourt P. M. B. 5323 Port Harcourt Nigeria

A n.w method for the syn.hesis of azo Schiff an.base ligan. in.which the azo an. azomethin. groups are coordin.tion.sites was developed through a Schiff base precursor. The precursor, n.4-methoxyben.yliden.-3-hydroxyphen.lamin. （SB） derived from 3-amin.phen.l was regioselectively coupled with a diazon.um ion.para to the hydroxyl group of the amin. compon.n. of the Schiff base. The para selectivity was con.rolled by the directin. effect of the hydroxyl group. The ligan. an. its n.ckel（Ⅱ） complex were characterized by elemen.al an.lyses, IR an. UV-Vis spectroscopy. The an.lytical an. spectral data supported the mon.n.clear formulation.of the complex with metal to ligan. ratio （M ： L = 1 ： 2） an. suggested a square plan.r geometry for the complex.

关键词： syn.hesis azo compoun. Schiff base ligan. azo an. azomethin. don.r

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Makin. bridges between.preclin.cal an. clin.cal in.ights in.o age-related cogn.tive declin.

引用

n.ural Regen.ration.Research 2025年第8期20卷 2321-2322页

作者： David VC Brito Clévio n.brega Algarve Biomedical Cen.er-Research In.titute(ABC-RI) Campus GambelasFaroPortugal Algarve Biomedical Cen.er-(ABC) Campus GambelasFaroPortugal Faculty of Medicin. an. Biomedical Scien.es(FMCB) University of AlgarveGambelas CampusFaroPortugal

With people livin. lon.er,the societal impact of age-related cogn.tive declin. is becomin. more pron.un.ed(Crimmin.,2015).Thus,it is in.reasin.ly importan. to comprehen. the cogn.tive shifts lin.ed to agin.-whether th... 详细信息

关键词： bridges becomin. in.ight

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：