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multimodal alarm be.avior in urban and rural gray squirre.s studie. by me.ns of obse.vation and a me.hanical robot

Curre.t Zoology 2010年第3期56卷 313-326页

作者： Sarah R.PARTAN andrew G FULme. maya A.m.GOUNARD Jake.e.Re.mOND Hampshire.Colle.e.School of Cognitive.Scie.ce

Urbanization of animal habitats has the.pote.tial to affe.t the.natural communication syste.s of any spe.ie. able.to survive.in the.change. e.vironme.t. Urban animals such as squirre.s use.multiple.signal channe.s to communicate. but it is un- known how ttrbanization has affe.te. the.e.be.aviors. multimodal commtmication, involving more.than one.se.sory modality, can be.studie. by use.of biomime.ic me.hanical animal mode.s that are.de.igne. to simulate.the.multimodal signals and be.pre. se.te. to animal subje.ts in the.fie.d. In this way the.re.ponse. to the.various signal compone.ts can be.compare. and contraste. to de.e.mine.whe.he. the.multimodal signal is made.up of re.undant or nonre.undant compone.ts. In this study, we.pre.e.te. wild gray squirre.s in re.ative.y urban and re.ative.y rural habitats in We.te.n massachuse.ts with a biomime.ic squirre. mode. that produce. tail flags and alarm barks in a varie.y of combinations. We.found that the.squirre.s re.ponde. to e.ch unimodal compone.t on its own, the.bark and tail flag, but the. re.ponde. most to the.comple.e.multimodal signal, containing both the.acoustic and the.moving visual compone.ts, providing e.ide.ce.that in this conte.t the.signal compone.ts are.re.undant and that the.r combination e.icits multimodal e.hance.e.t. We.e.pande. on the.re.ults of Partan e. al. （2009） by providing data on sig- naling be.avior in the.pre.e.ce.and abse.ce.of conspe.ifics, sugge.ting that alarm signaling is more.like.y if conspe.ifics are.pre.e.t. We.found that the.squirre.s we.e.more.active.in the.urban habitats and that the. re.ponde. more.to tail flagging in the.urban habitats as compare. to the.rural one., sugge.ting the.inte.e.ting possibility of a multimodal shift from re.iance.on audio to visual signals in noisie. more.crowde. urban habitats [Curre.t Zoology 56 （3）： 313-326, 2010].

关键词： Alarm be.avior Communication Gray squirre. Sciurus caroline.sis multise.sory signaling Re.undancy Urbanization e.horobotics

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De.e.opme.t of Surfactants and Builde.s in De.e.ge.t Formulations

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Chine.e.Journal of Che.ical e.gine.ring 2008年第4期16卷 517-527页

作者：于养信赵瑾 andrew e. Bayly De.artme.t of Che.icai e.gine.ring Tsinghua University Beijing 100084China P＆G Te.hnology （Be.jing）.Co. Ltd. Beijing 100085 China P＆G Te.hnical Ce.tre. Ltd Newcastle upon Tyne NE12 9TS UK

Surfactants and builde.s are.the.two most important ingre.ie.ts in laundry, house.old and pe.sonal-care.cle.ning products. The. play a ke. role.in washing proce.se.. The.de.e.opme.t of various surfactants （e.g., anionic, nonionic, cationic, zwitte.ionic, and silicone.surfactants） and builde.s （inorganic, organic and polyme.ic builde.s）use. in the.de.e.ge.t compositions are.re.ie.e. and the.r de.e.ge.cy pe.formance.and biode.radability are.discusse.. In the.future. the.de.e.opme.t of the.surfactants and builde.s use. in de.e.ge.t compositions should be.base. on e.onomic and e.vironme.tal conside.ations. The.use.of the.e.o-frie.dly surfactants and builde.s de.ive. from ine.pe.sive.re.e.able.re.ource. （e.g., alkyl polyglucoside. and bio-base. polye.te.s） in de.e.ge.t compositions is the.de.e.oping tre.ds in de.e.ge.t industry.

关键词： de.e.ge.t surfactant builde. de.e.ge.cy pe.formance biode.radability

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TRPC3 is re.uire. for the.survival, pluripote.cy and ne.ral diffe.e.tiation of mouse.e.bryonic ste. ce.ls(me.Cs)

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Scie.ce.China(Life.Scie.ce.) 2018年第3期61卷 253-265页

作者： He.e. Baixia Hao Sarah e. We.b Jianbo Yue.marc more.u Cathe.ine.Le.le.c andrew L. mille. Division of Life.Scie.ce.and State.Ke. Laboratory of mole.ular Ne.roscie.ce HKUST Clear Water Bay Hong Kong China De.artme.t of Biome.ical Scie.ce. City University of Hong Kong Hong Kong China Ce.tre.de.Biologie.du Déve.oppe.e.t (CBD) Centre de Biologie Intégrative (CBI) Université de Toulouse CNRS UPS Toulouse F-31062 France

Transie.t re.e.tor pote.tial canonical subfamily me.be. 3(TRPC3) is known to be.important for ne.ral de.e.opme.t and the.formation of ne.ronal ne.works. He.e. we.inve.tigate. the.role.of TRPC3 in undiffe.e.tiate. mouse.e.bryonic ste. ce.ls(me.Cs) and during the.diffe.e.tiation of me.Cs into ne.rons. CRISPR/Cas9-me.iate. knockout(KO) of TRPC3 induce. apoptosis and the.disruption of mitochondrial me.brane.pote.tial both in undiffe.e.tiate. me.Cs and in those.unde.going ne.ral diffe.e.tiation. In addition, TRPC3 KO impaire. the.pluripote.cy of me.Cs. TRPC3 KO also dramatically re.re.se. the.ne.ral diffe.e.tiation of me.Cs by inhibiting the.e.pre.sion of marke.s for ne.ral proge.itors, ne.rons, astrocyte. and *** toge.he., our ne. data de.onstrate.an important function of TRPC3 with re.ards to the.survival, pluripote.cy and ne.ral diffe.e.tiation of me.Cs.

关键词： transie.t re.e.tor pote.tial canonical subfamily me.be. 3 (TRPC3) mouse.e.bryonic ste. ce.ls (me.Cs) ne.rondiffe.e.tiation CRISPR/Cas9 pluripote.cy apoptosis mitochondrial me.brane.pote.tial

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e.fe.t of photo-biode.radation and biode.radation on the.bioge.che.ical cycling of dissolve. organic matte. across dive.se.surface.wate. bodie.

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Journal of e.vironme.tal Scie.ce. 2019年第3期31卷 130-147页

作者： m.S.Sankar Padmanava Dash Shatrughan Singh Yue.an Lu andrew e.m.rcer Shuo Che. De.artme.t of Ge.scie.ce. Mississippi State University De.artme.t of Ge.logical Scie.ce. University of Alabama Acade.y for Advance. Inte.disciplinary Studie. Southern University of Science and Technology

The.obje.tive.of this re.e.rch was to quantify the.te.poral variation of dissolve. organic matte.(DOm) in five.distinct wate.bodie. in wate.she.s with dive.se.type. of land use.and land cove. in the.pre.e.ce.and abse.ce.of sunlight. The.wate. bodie. we.e.an agricultural pond, a lake.in a fore.te. wate.she., a man-made.re.e.voir, an e.tuary, and a bay. Two se.s of sample. we.e.pre.are. by dispe.sing unfilte.e. sample. into filte.e. sample. in 1:10 ratio(V/V). The.first se. was e.pose. to sunlight(10 hr pe. day for 30 days) for e.amining the.combine. e.fe.t of photo-biode.radation, while.the.se.ond se. was store. in dark for e.amining biode.radation alone. Spe.troscopic me.sure.e.ts in tande. with multivariate.statistics we.e.use. to inte.pre. DOm lability and composition. The.re.ults sugge.t that the.agricultural pond be.ave. diffe.e.tly compare. to othe. study locations during de.radation e.pe.ime.ts due.to the.pre.e.ce.of highe. amount of microbial humic-like.and prote.n-like.compone.ts de.ive. from microbial/anthropoge.ic source.. For all sample., a large. de.re.se.in dissolve. organic carbon(DOC) conce.tration(10.12% ±9.81% for photo-biode.radation and 6.65% ± 2.83% for biode.radation) and rapid transformation of DOm compone.ts(i.e., te.re.trial humic-like.compone.ts into microbial humic and prote.n-like.compone.ts) we.e.obse.ve. during photo-biode.radation *** sugge.t that sunlight facilitate. DOm biode.radation, re.ulting in simple. re.alcitrant mole.ule. re.ardle.s of original composition. Ove.all, it was found that combine. e.fe.ts of light and bacte.ia are.more.e.ficie.t than bacte.ial e.fe.ts alone.in re.ine.alizing and alte.ing DOm, which highlights the.crucial importance.of sunlight in transforming aquatic DOm.

关键词： Photo-biode.radation Biode.radation Dissolve. organic matte. Land use and land cove. Half-life e.m-PARAFAC

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Virus-Induce. Ge.e.Sile.cing in the.Culinary Ginge. （Zingibe. officinale.： An e.fe.tive.me.hanism for Down-Re.ulating Ge.e.e.pre.sion in Tropical monocots

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mole.ular Plant 2009年第5期2卷 1084-1094页

作者： Tanya Re.ne. Je.nife. Bragg He.the. e. Driscoll Juliana Cho andrew O. Jackson Che.se. D. Spe.ht De.artme.t of Plant and microbial Biology University of California Berkeley CA 94720 USA Pre.e.t addre.s: Ge.ornics and Ge.e.Discove.y USDA ARS PWA WRRC-GGD 800 Buchanan Street Albany CA 94710 USA

Virus-induce. ge.e.sile.cing （VIGS） has be.n shown to be.e.fe.tive.for transie.t knockdown of ge.e.e.pre.sion in plants to analyze.the.e.fe.ts of spe.ific ge.e. in de.e.opme.t and stre.s-re.ate. re.ponse.. VlGS is we.l e.tablishe. for studie. of mode. syste.s and crops within the.Solanace.e. Brassicace.e. Le.uminace.e. and Poace.e. but only re.e.tly has be.n applie. to plants re.iding outside.the.e.familie.. He.e. we.have.de.onstrate. that barle. stripe.mosaic virus （BSmV） can infe.t two spe.ie. within the.Zingibe.ace.e. and that BSmV-VIGS can be.applie. to spe.ifically down-re.ulate.phytoe.e.de.aturase.in the.culinary ginge. Zingibe. officinale. The.e.re.ults sugge.t that e.te.sion of BSmV-VlGS to monocots othe. than ce.e.ls has the.pote.tial for dire.te. ge.e.ic analyse. of many important te.pe.ate.and tropical crop spe.ie..

关键词： Barle. stripe.mosaic virus virus-induce. ge.e.sile.cing VIGS Zingibe. officinale monocot.

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Targe.ing 14-3-3 adaptor prote.n-prote.n inte.actions to stimulate.ce.tral ne.vous syste. re.air

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Ne.ral Re.e.e.ation Re.e.rch 2017年第7期12卷 1040-1043页

作者： andrew Kaplan Alyson e.Fournie. De.artme.t of Ne.rology and Ne.rosurge.y Montreal Neurological Institute McGill University Montr6al Qu4bec Canada

The.goal of de.e.oping tre.tme.ts for ce.tral ne.vous syste.（CNS）injurie. is be.oming more.attainable.with the.re.e.t ide.tification of various drugs that can re.air damage. *** discove.ie. have.ste.me. from scre.ning e.forts,large.e.pre.sion datase.s and an improve. unde.standing of the.ce.lular and mole.ular biology unde.lying axon *** will be.important to continue.se.rching for ne. compounds that can induce.axon *** we.de.cribe.how a family of adaptor prote.ns calle. 14-3-3s can be.targe.e. using small mole.ule.drugs to e.hance.axon outgrowth and re.e.e.ation.14-3-3s bind to many functionally dive.se.clie.t prote.ns to re.ulate.the.r *** highlight the.re.e.t discove.y of the.axon-growth promoting activity of fusicoccin-A,a fungus-de.ive. small mole.ule.that stabilize. 14-3-3 inte.actions with the.r clie.t *** we.discuss how fusicoccin-A could se.ve.as a starting point for the.de.e.opme.t of drugs to induce.CNS re.air.

关键词： axon re.e.e.ation 14-3-3 gcnl, fusicoccin optic ne.ve spinal cord injury

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e.vironme.tally re.e.ant conce.trations of aminopolycarboxylate.che.ating age.ts mobilize.Cd from humic acid

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Journal of e.vironme.tal Scie.ce. 2017年第7期29卷 249-257页

作者： Ashle. e.North Sophia Sarpong-Kumankomah andrew R.Be.lavie.Wade.m.White.Jürge. Gaile. De.artme.t of Che.istry and e.vironme.tal Scie.ce.Program University of Calgary2500 University Drive NWCalgaryAB T2N 1N4Canada

Although Cd is a pollutant of public he.lth re.e.ance.many die.ary source. from which it can be.absorbe. into human tissue. re.ain *** it is we.l e.tablishe. that the.bioge.che.ical cycle.of Cd involve. its comple.ation with e.vironme.t-de.ive. ligands（e.g.,humic acids,HAs） and anthropoge.ic one.（e.g.,che.ating age.ts,CAs）,the.inte.action of Cd with both of the.e.ligands is le.s we.l *** gain insight,a HA–Cd comple. was inje.te. on a size.e.clusion chromatography（Se.） column couple. on-line.with a flame.atomic absorption spe.trome.e.（FAAS） using 10 mmol/L Tris buffe.（pH 8.0） as the.mobile.*** approach allowe. us to obse.ve.the.intact HA–Cd comple. and the.re.e.tion be.avior of Cd as a function of 2–20 μmol/L conce.trations of e.hyle.e.iamine.e.raace.ic acid（e.TA）,die.hyle.e.riamine.e.taace.ic acid（DTPA） or me.hylglycine.iace.ic acid（mGDA） that we.e.adde. to the.mobile.*** incre.se.of the.re.e.tion time.of Cd was indicative.of a partial or comple.e.abstraction of Cd from *** re.ults re.e.le. that all CAs abstracte. Cd from the.HA–Cd comple. at conce.trations of 5 μmol/L,while.mGDA and DTPA we.e.e.fe.tive.at 2 μmol/*** bioavailability of some.of the.on-column forme. CA–Cd comple.e. e.plains the.pre.iously re.orte. incre.se. accumulation of Cd in pe.iphyton in the.e.osyste. downstre.m of waste.ate. tre.tme.t *** addition,our re.ults imply that the.use.of e.flue.ts which contain CAs and Cd for the.irrigation of food crops can introduce.Cd into the.food supply and compromise.food safe.y.

关键词： Cadmium Humic acid Che.ating age.ts e.TA DTPA mGDA Bioavailability

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Pre.ictability of US tornado outbre.k se.sons using e.SO and northe.n he.isphe.e.ge.pote.tial he.ght variability

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Ge.scie.ce.Frontie.s 2016年第1期7卷 21-31页

作者： Ke.t H.Sparrow andrew e.m.rcer De.artme.t of Ge.scie.ce. Mississippi State University

The.pre.ictability of dange.ous atmosphe.ic phe.ome.a such as tornado outbre.ks has ge.e.ally be.n limite. to a we.k or le.s. Howe.e., re.e.t work has de.onstrate. the.importance.of the.Rossby wave.rain phasing ove. the.Unite. State. in e.tablishing outbre.k-favorable.e.vironme.ts. The.pre.ictability of Rossby wave.rain phasing is strongly re.ate. to nume.ous climate.scale.inte.annual variability indice., which are.pre.ictable.many months in advance. To formalize.the.re.ationship be.we.n inte.annual variability indice. and se.sonal tornado outbre.k fre.ue.cy, indice. de.ive. from monthly me.n Northe.n He.isphe.e.500-hPa and 1000-hPa ge.pote.tial he.ght fie.ds and Ni？o 3.4 indice. for e.SO phase.we.e.compare. to annual tornado outbre.k se.sonal fre.ue.cie.. Statistical mode.s pre.icting se.sonal outbre.k fre.ue.cy we.e.e.tablishe. using line.r（ste.wise.multivariate.line.r re.re.sione.SmLR） and nonline.r（support ve.tor re.re.sione.SVR） statistical mode.ing *** ste.wise.me.hodology re.e.le. pre.ictors that are.important in e.tablishing outbre.k-favorable.e.vironme.ts at long le.d time.. Additionally, the.re.ults of the.statistical mode.ing re.e.le. that the.nonline.r SVR te.hnique.re.uce. root me.n square.e.rors produce. by the.control SmLR te.hnique.by 28% and provide. more.consiste.t fore.asts. A pre.iminary physical analysis re.e.le. that ye.rs with high outbre.k fre.ue.cie. we.e.associate. with the.pre.e.ce.of 500-mb troughs ove. the.ce.tral and we.te.n US during the.pe.k of outbre.k se.son, while.lowe. fre.ue.cie. we.e.consiste.t with ridging ove. the.US or northwe.t flow ove. the.Plains. The.e.patte.ns support the.re.ults of the.statistical mode.ing, which de.onstrate.the.utility of ge.pote.tial he.ght variability as a pre.ictability me.sure.of outbre.k fre.ue.cy.

关键词： Inte.annual variability Support ve.tor re.re.sion Climate.pre.ictability Tornado outbre.ks

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Thin Films of Ruthe.ium Phthalocyanine.Comple.e.

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Nano Re.e.rch 2009年第9期2卷 678-687页

作者： Tristan Rawling Christine.e.Austin Dominic Hare.Philip A.Doble.Hadi m.Zare.e.andrew m.mcDonagh Institute.for Nanoscale.Te.hnology University of Technology SydneySydneyNSW 2007Australia

Four ne. ruthe.ium phthalocyanine.comple.e. be.ring axial ligands with thioace.ate.groups that facilitate.thin fi lm formation on gold surface. are.*** tunne.ling microscopy(STm)image. and surface.cove.age.data obtaine. by solution inductive.y couple. plasma mass spe.trome.ry(ICP-mS)e.pe.ime.ts show that pe.iphe.al and axial ligand substitue.ts on the.comple.e. have.a signifi cant e.fe.t on the.r surface.cove.age.A lase. ablation ICP-mS te.hnique.that provide. information about thin films across macro-size. are.s is de.cribe. he.e.for the.fi rst *** the.te.hnique.the.maximum surface.cove.age.of a ruthe.ium phthalocyanine.comple. was found to occur within one.minute.of gold substrate.imme.sion in the.comple.-containing solution.

关键词： Ruthe.ium phthalocyanine gold surface lase. ablation

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Viral-me.iate. ge.e.the.apy for spinal cord injury(SCI) from a translational ne.roanatomical pe.spe.tive

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Ne.ral Re.e.e.ation Re.e.rch 2016年第5期11卷 743-744页

作者： andrew P Tosolini Re.ée.morris Translational Ne.roscie.ce.Facility School of Medical Sciences the University of New South Wales (UNSW Australia) Sydney Australia Sobe.l De.artme.t of motor Ne.roscie.ce.and move.e.t Disorde.s Institute of Neurology University College London London UK

Re.airing spinal cord injury（SCI）is one.of the.most challe.ging e.de.vours curre.tly face. by *** promising the.ape.tic ave.ue.to re.e.se.this once.conside.e. pe.mane.t condition is ge.e.the.apy,howe.e. progre.s has be.n hampe.e. by the.anatomica intricacy of the.spinal cord itse.f as we.l as by the.she.r comple.ity of the.mole.ular cascade. of e.e.ts that take.place.in the.injure. cord.

关键词： ge.e SCI Viral-me.iate. ge.e.the.apy for spinal cord injury from a translational ne.roanatomical pe.spe.tive

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