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Insights into the kinetics–morphology relationship of 1-, 2-, and 3D TiNb_(2)O_(7) anodes for Li-ion storage

Nano Research 2024年第4期17卷 2770-2780页

作者： Wenlei xu Yaolin xu Veronika Grzimek andrea Martin Thorsten Schultz Patrícia ARusso Yan Lu Norbert Koch Nicola Pinna Department of Chemistry IRIS Adlershof and the Center for the Science of Materials BerlinHumboldt-Universität zu BerlinBrook-Taylor-Str.212489 BerlinGermany Department of Electrochemical Energy Storage Helmholtz-Zentrum Berlin für Materialien und EnergieHahn-Meitner-Platz 114109 BerlinGermany Institut für Physik and IRIS Adlershof Humboldt-Universität zu BerlinBrook-Taylor-Str.212489 BerlinGermany Joint Research Group of Molecular Systems Helmholtz-Zentrum Berlin für Materialien und Energie12489 BerlinGermany

Understanding the influence of electrode material’s morphology on electrochemical behavior is of great significance for the development of rechargeable batteries,however,such studies are often limited by the inability to precisely control the morphology of electrode ***,nanostructured titanium niobium oxides(TiNb_(2)O_(7))with three different morphologies(one-dimensional(1D),two-dimensional(2D),and three-dimensional(3D))were synthesized via a facile microwave-assisted solvothermal *** influence of the morphological dimension of TiNb_(2)O_(7) as electrode material on the electrochemical performance in Li-ion batteries(LIBs)and the underlying correlation with the electrochemical kinetics were studied in detail.2D TiNb_(2)O_(7)(TNO-2D)shows a superior rate capability and cycling stability,associated with improved kinetics for charge transfer and Li-ion diffusion,compared to the 1D and 3D *** X-ray diffraction measurements reveal the structural stability and crystallographic evolution of TNO-2D upon lithiation and delithiation and correlate the Li-ion diffusion kinetics with the lattice evolution during battery charge and ***,carbon-coated TNO-2D achieves enhanced rate capability(205 mAh·g^(-1) at 50 C)and long-term cycling stability(87%after 1000 cycles at 5 C).This work provides insights into the rational morphology design of electrode materials for accelerated charge transfer and enhanced fast-charging capability,pushing forward the development of electrode materials for high-power rechargeable batteries in future energy storage.

关键词： morphological dimension electrochemical kinetics lithium-ion batteries TiNb_(2)O_(7) structural evolution

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Validity of self-reported male sexual function scales in a young Chinese population:a comparative study with clinician-assisted evaluation

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Asian Journal of Andrology 2024年第3期26卷 321-327页

作者： Hui Zhang Elena Colonnello Erika Limoncin Tommaso B Jannini xu-Chong Tu andrea Sansone Emmanuele A Jannini Yan Zhang Department of Infertility and Sexual Medicine Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510000China Chair of Endocrinology and MedicalSexology(ENDOSEX) Department of Experimental MedicineUniversity of Rome Tor VergataRome 00133Italy Department of Urology First Affiliated Hospital ofGuangzhou University of Chinese MedicineGuangzhou 510000China Section of Medical Pathophysiology Food Science and EndocrinologySapienza University of RomeRome 00133Italy School of Psychiatry Department of Systems MedicineUniversity of Rome Tor VergataRome 00133Italy

Psychometric scales,commonly used to gauge sexual function,can sometimes be influenced by response *** our researchfrom June 2020 to April 2021,we examined the accuracy of self-reported sexual function *** invited patients from theDepartment of Infertility and Sexual Medicine at the Third Affiliated Hospital of Sun Yat-sen University(Guangzhou,China),whohave male sexual dysfunction,to participate by filling out a self-reported version of a specific *** addition,they wentthrough a clinician-assisted version of this questionnaire,encompassing tools such as the Premature Ejaculation Diagnostic Tool(PEDT),the 6-item International Index of Erectile Function(IIEF-6),the Erection Hardness Scale(EHS),and the MasturbationErection Index(MEI).Using the clinician-assisted version as a reference,we categorized patients and applied various statisticalmethods,such as the Chi-square test,intraclass correlation coefficient(ICC),logistic regression,and the Bland–Altman plot,to gauge *** our study with 322 participants,we found that while there were no notable discrepancies in error ratesbased on our categorization,certain scales showed significant differences in terms of overestimation and underestimation,withthe exception of the *** positive diagnosis rate consistency between the self-reported and clinician-assisted versions *** ICC values between the two versions across the scales were indicative of remarkable *** findings showthat the self-reported versions of tools such as EHS,IIEF-6,MEI,and PEDT are credible and hold clinical ***,employing a dual-diagnosis approach might be more prudent to circumvent potential misdiagnoses.

关键词： psychometry scale sexual function sexual health

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Circulating microRNA expression and nonalcoholic fatty liver disease in adolescents with severe obesity

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World Journal of Gastroenterology 2024年第4期30卷 332-345页

作者： Yi-Jie Li Brittney O Baumert Nikos Stratakis Jesse A Goodrich Hao-Tian Wu Jing-xuan He Yin-Qi Zhao Max T Aung Hong-xu Wang Sandrah P Eckel Douglas I Walker Damaskini Valvi Michele A La Merrill Justin R Ryder Thomas H Inge Todd Jenkins Stephanie Sisley Rohit Kohli Stavra A Xanthakos andrea A Baccarelli Rob McConnell David V Conti Lida Chatzi Department of Population and Public Health Sciences Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCA 90032United States Barcelona Institute of Global Health Barcelona Institute of Global HealthBarcelona 08036Spain Department of Environmental Health Sciences Mailman School of Public HealthColumbia UniversityNew YorkNY 10032United States Gangarosa Department of Environmental Health Rollins School of Public HealthEmory UniversityAtlantaGA 30329United States Department of Environmental Medicine and Public Health Icahn School of Medicine at Mount SinaiNew YorkNY 10029United States Department of Environmental Toxicology University of CaliforniaDavisCA 95616United States Department of Surgery Lurie Children’s Hospital of ChicagoChicagoIL 60611United States Northwestern University Feinberg School of Medicine Northwestern UniversityChicagoIL 60611United States Division of Biostatistics and Epidemiology Cincinnati Children's Hospital Medical CenterCincinnatiOH 45229United States Department of Pediatrics University of Cincinnati College of MedicineCincinnatiOH 45229United States Department of Pediatrics Children’s Nutrition Research Center USDA/ARSBaylor College of MedicineHoustonTX 77030United States Department of Gastroenterology Children’s Hospital Los AngelesLos AngelesCA 90027United States Division of Gastroenterology Hepatology and NutritionCincinnati Children's Hospital Medical CenterCincinnatiOH 45229United States

BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is one of the most common chronic liver diseases in children and *** ranges in severity from isolated hepatic steatosis to nonalcoholic steatohepatitis(NASH),wherein hepatocellular inflammation and/or fibrosis coexist with *** microRNA(miRNA)levels have been suggested to be altered in NAFLD,but the extent to which miRNA are related to NAFLD features remains *** analysis tested the hypothesis that plasma miRNAs are significantly associated with histological features of NAFLD in *** To investigate the relationship between plasma miRNA expression and NAFLD features among adolescents with *** This study included 81 adolescents diagnosed with NAFLD and 54 adolescents without NAFLD from the Teen-Longitudinal Assessment of Bariatric Surgery ***-operative core liver biopsies were collected from participants and used to characterize histological features of *** samples were collected during surgery for miRNA profiling.A total of 843 plasma miRNAs were profiled using the HTG EdgeSeq *** examined associations of plasma miRNAs and NAFLD features using logistic regression after adjusting for age,sex,race,and other key *** Pathways Analysis was used to identify biological functions of miRNAs that were associated with multiple histological features of *** We identified 16 upregulated plasma miRNAs,including miR-193a-5p and miR-193b-5p,and 22 downregulated plasma miRNAs,including miR-1282 and miR-6734-5p,in adolescents with ***,52,16,15,and 9 plasma miRNAs were associated with NASH,fibrosis,ballooning degeneration,and lobular inflammation,***,16 miRNAs were associated with two or more histological features of *** those miRNAs,miR-411-5p was downregulated in NASH,ballooning,and fibrosis,while miR-122-5p,miR-1343-5p,miR-193a-5p,miR-193b-5p,and miR-7845-5p were consistently and posi

关键词： MicroRNA Nonalcoholic fatty liver disease Non-alcoholic steatohepatitis Liver fibrosis Lobular inflammation Ballooning degeneration

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Stereotactic radiosurgery for haemorrhagic cerebral cavernous malformation:a multi-institutional,retrospective study

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Stroke & Vascular Neurology 2024年第3期9卷 221-229,I0130,I0131页

作者： Chloe Dumot Georgios Mantziaris Sam Dayawansa Zhiyuan xu Stylianos Pikis Selcuk Peker Yavuz Samanci Gokce D Ardor Ahmed M Nabeel Wael A Reda Sameh R Tawadros Khaled Abdelkarim Amr M N El-Shehaby Reem M Emad Eldin Ahmed H Elazzazi Nuria Martínez Moreno Roberto MartínezÁlvarez Roman Liscak Jaromir May David Mathieu Jean-Nicolas Tourigny Manjul Tripathi Akshay Rajput Narendra Kumar Rupinder Kaur Piero Picozzi andrea Franzini Herwin Speckter Wenceslao Hernandez Anderson Brito Ronald E Warnick Juan Alzate Douglas Kondziolka Greg N Bowden Samir Patel Jason Sheehan Department of Neurological Surgery Hospices Civils de LyonLyonFrance Department of Neurological Surgery University of VirginiaCharlottesvilleVirginiaUSA Department of Neurosurgery Koc University School of MedicineIstanbulTurkey Gamma-knife Center Nasser institute HospitalCairoEgypt Neurosurgery Department Benha UniversityBenhaEgypt Departments of Neurosurgery Ain Shams UniversityCairoEgypt Department of Clinical Oncology Ain Shams UniversityCairoEgypt Department of Radiation Oncology National Cancer InstituteCairo UniversityGizaEgypt Faculty of Medicine Extended Modular ProgramAin Shams UniversityCairoEgypt Department of Radiosurgery Rúber Internacional HospitalMadridSpain Department of Stereotactic and Radiation Neurosurgery Na Homolce HospitalPragueCzech Republic Neurosurgery Centre de recherche du CHUSUniversitéde SherbrookeSherbrookeQuebecCanada Neurosurgery PGIMERChandigarhChandigarhIndia Radiation Therapy PGIMERChandigarhChandigarhIndia Neurosurgery IRCCS Istituto Clinico HumanitasRozzanoMilanItaly Dominican Gamma Knife Center and Radiology Department CEDIMATSanto DomingoDominican Republic Gamma Knife Center Mayfield ClinicThe Jewish Hospital-Mercy HealthCincinnatiOhioUSA Neurosurgery NYU Langone HealthNew YorkNew YorkUSA Neurosurgery University of AlbertaEdmontonAlbertaCanada Division of Radiation Oncology Department of OncologyUniversity of AlbertaEdmontonAlbertaCanada

Background Cerebral cavernous malformations(CCMs)frequently manifest with *** radiosurgery(SRS)has been employed for CCM not suitable for *** effect on reducing haemorrhage risk is still *** aim of this study was to expand on the safety and efficacy of SRS for haemorrhagic *** This retrospective multicentric study included CCM with at least one haemorrhage treated with single-session *** annual haemorrhagic rate(AHR)was calculated before and after *** event analysis and Cox regression were used to evaluate factors associated with *** radiation effects(AREs)and occurrence of new neurological deficits were *** The study included 381 patients (median age:37.5 years(Q1–Q3:25.8–51.9))with 414 *** AHR from diagnosis to SRS excluding the first haemorrhage was 11.08 per 100 CCM-years and was reduced to 2.7 per 100 CCM-years after *** recurrent event analysis,SRS,HR 0.27(95%CI 0.17 to 0.44),p13 Gy,HR 2.27(95%CI 1.20 to 4.32),p=0.012 and the presence of DVA,HR 2.08(95%CI 1.00 to 4.31),p=0.049 were factors associated with higher probability of post-SRS ***-SRS haemorrhage was symptomatic in 22 out of 381(5.8%)patients,presenting with transient(15/381)or permanent(7/381)neurological *** occurred in 11.1%(46/414)CCM and was responsible for transient neurological deficit in 3.9%(15/381)of the patients and permanent deficit in 1.1%(4/381)of the *** doses>13 Gy and CCM volume>0.7 cc were associated with increased risk of ARE.

关键词： doses haemorrhagic diagnosis

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An Axiom System of Probabilistic Mu-Calculus

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Tsinghua Science and Technology 2022年第2期27卷 372-385页

作者： Wanwei Liu Junnan xu David N.Jansen andrea Turrini Lijun Zhang College of Computer Science National University of Defense TechnologyChangsha 410073China State Key Laboratory of Computer Science Institute of SoftwareChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100039China Institute of Intelligent Software Guangzhou 511458China

Mu-calculus(a.k.a.μTL)is built up from modal/dynamic logic via adding the least fixpoint operatorμ.This type of logic has attracted increasing attention since Kozen’s seminal work.PμTL is a succinct probabilistic extension of the standardμTL obtained by making the modal operators *** of this logic,such as expressiveness and satisfiability decision,have been studied *** consider another important problem:the axiomatization of that *** extending the approaches of Kozen and Walukiewicz,we present an axiom system for Pμ*** addition,we show that the axiom system is complete for aconjunctive formulas.

关键词： PμTL axiom system aconjunctive formula tableau approach

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Towards a standardisation for digital inputs and outputs of protection functions in IEC 60255 series

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Protection and Control of Modern Power Systems 2022年第1期7卷 382-392页

作者： Volker Leitloff Hao Chen Dehui Chen andrea Bonetti Lei xu Ahmed Mohamed Carl Byman French Transmission Network Operator Rte ParisFrance State Grid Jiangsu Electric Power Co. Ltd.NanjingChina State Grid Electric Power Institute NanjingChina Royal Institute of Technology StockholmSweden NR Elec-tric Co. Ltd.NanjingChina Scottish and Southern Energy Network(SSEN) GlasgowUK Hitachi Energy VästeråsSweden.

Fully digitalized substations using IEC 61850 process bus are being introduced all over the *** utilities have featured pilot projects,demonstrators or even industrial scale deployment of these Fully Digital Protection,Auto-mation and Control Systems(FD-PACS).Product standards such as profiles for Instrument Transformers have been developed and published(IEC 61869-6 and IEC 61869-9 by TC 38-Instrument Transformers).This raises the question about the standards for digitally interfaced protection *** 2016,IEC TC 95(Measuring relays and protection equipment)charged a working group to investigate this subject and to elaborate recommendations concerning requirements and testing of protection IED with digital inputs and outputs for protection standards(IEC 60255-1xx series).For protection functions,publisher/subscriber based data streams are supposed to comply with IEC 61850 and IEC 61869 *** holds in particular for Sampled Values(SV)representing energising inputs of the protection function,and is also applicable to Generic Object Oriented Substation Event(GOOSE)which can be used for input or output of protection *** attributes of published data depend on the operational and connection status of the function and the hosting *** addition,protection functions have to take into account the information regarding the time synchronisation of the received SV and other *** paper gives an overview of these features and the proposed way to take them into account in the IEC 60255 standard *** describes the progress of WG 2 and relates it to existing standardization documents.

关键词： Process bus Protection function Digital interface SAMU LPIT Standards IEC 61850

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Electrodeposited Sulfur and CoxS Electrocatalyst on Buckypaper as High-Performance Cathode for Li-S Batteries

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Nano-Micro Letters 2020年第10期12卷 263-275页

作者： Yi Zhan andrea Buffa Linghui Yu Zhichuan Jxu Daniel Mandler School of Materials Science and Engineering Nanyang Technological UniversitySingapore 639798Singapore Institute of Chemistry The Hebrew University of Jerusalem9190401 JerusalemIsrael Campus for Research Excellence and Technological Enterprise(CREATE) Singapore-HUJ Alliance for Research and Enterprise(SHARE)Singapore 138602Singapore

Lithium-sulfur batteries(LSBs)are considered as the next generation of advanced rechargeable batteries because of their high energy *** this study,sulfur and CoxS electrocatalyst are deposited on carbon nanotube buckypaper(S/CoxS/BP)by a facile electrodeposition method and are used as a binder-free high-performance cathode for *** sulfur is deposited on buckypaper by electrooxidation of a polysulfide solution(-S6^2-).This approach substantially increased the current and time efficiency of sulfur electrochemical deposition on conductive material for LSBs.S/CoxS/BP cathode could deliver an initial discharge capacity as high as 1650 mAh g^-1 at 0.1 C,which is close to the theoretical capacity of *** current rate of 0.5 C,the S/CoxS/BP has a capacity of 1420 mAh g^-1 at the first cycle and 715 mAh g^-1 after 500 cycles with a fading rate of 0.099%per *** high capacity of S/CoxS/BP is attributed to both the homogeneous dispersion of nanosized sulfur within BP and the presence of CoxS *** sodium dodecyl sulfate(SDS)pretreatment of BP renders it polarity to bind polysulfides and thus facilitates the good dispersibility of nanosized sulfur within *** catalyst accelerates the kinetics of polysulfide conversion and reduces the presence of polysulfide in the cathode,which suppresses the polysulfide diffusion to anode,i.e.,the shuttle *** mitigation of the active material loss improves not only the capacity but also the cyclability of S/CoxS/BP.

关键词： Electrodeposition Lithium sulfur batteries Buckypaper Electrocatalysts

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New species of Saurichthys(Actinopterygii:Saurichthyidae)from Middle Triassic(Anisian)of Yunnan Province,China

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Acta Geologica Sinica(English Edition) 2009年第3期83卷 440-450页

作者： WU Feixiang SUN Yuanlin HAO Weicheng JIANG Dayong xu Guanghui SUN Zuoyu andrea TINTORI Key Laboratory of Orogenic Belts and Crustal Evolution School of Earth and Space Sciences Peking University Beijing 100871 China Dipartimento di Scienze della Terra Universita degli Studi di Milano Via Mangiagalll34 20133 Milano Italy

Saurichthys dawaziensis sp. nov., from the third member of the Gejiu Formation （Anisian of Middle Triassic） in the vicinity of Luoping, Yunnan Province, is a small to mediumsized saurichthyid fish. It is characterized by the efferent pseudobranchial arteries penetrating on the parasphenoid and the mandible sensory canal with a branch in the angular. The new species is more derived than the Lower Triassic species in having a relatively narrow postorbital region, short preopercular, single ossification of the sclerotic ring, small haemal arches between the pelvic fins and the anal fin without ossified spines, and in the absence of quadratojugal. It is more primitive than the Middle and Upper Triassic Saurichthys in having fringing fulcra and numerous segments in the unpaired fins, and the presence of both prae- and post-zygapophyses in the neural arches. Some anatomic changes related to the vertebral column and unpaired fins of the genus are also discussed.

关键词： Actinopterygian fishes Saurichthyidae Saurichthys Middle Triassic Yunnan

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Lonicera caerulea polyphenols inhibit fat absorption by regulating Nrf2-ARE pathway mediated epithelial barrier dysfunction and special microbiota

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Food Science and Human Wellness 2023年第4期12卷 1309-1322页

作者： Yuehua Wang Ningxuan Gao andrea Nieto-Veloza Lingxi Zhou Xiyun Sun xu Si Jinlong Tian Yang Lin Xinyao Jiao Bin Li College of Food Science Shenyang Agricultural UniversityShenyang 110161China Key Laboratory of Healthy Food Nutrition and Innovative Manufacturing of Liaoning Province Shenyang 110161China Instituto de Ciencia y Tecnología de Alimentos Universidad Nacional de ColombiaBogotá111311Colombia Key Laboratory of Industrial Biotechnology Ministry of EducationSchool of BiotechnologyJiangnan UniversityWuxi 214122China College of Food Science and Technology Zhejiang University of TechnologyHangzhou 310014China

Scope:High-fat diet(HFD)induces imbalance in the small intestine environment,where fat digestion and absorption mainly take *** study aimed to elucidate the mechanisms by which Lonicera caerulea polyphenols(LCP)might inhibit fat absorption,from the perspective of small intestine microbiota and epithelial barrier *** and results:Male Sprague-Dawley rats were given HFD with or without co-administration of LCP for 8 *** results showed that LCP supplementation significantly decreased the levels of serum triglycerides(TG),total cholesterol(TC),and low-density lipoprotein cholesterol(LDL-C),and increased the contents of fecal sterols,in HFD *** also inhibited the dysfunction of the small intestine epithelial barrier,via alleviating the oxidative stress activated by Nrf2-ARE pathway,and by modulating the expressions of pro-inflammatory factors such as tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),cyclooxygenase-2(COX-2),nuclear factor kappa-B p65(NF-κB p65)and inducible nitric oxide synthase(iNOS)in the small ***,LCP administration restored the balance in small intestine microbiota and increased the abundance of the specific bacteria,such as Lactobacillus,involved in fat ***:Our results demonstrated that LCP may be beneficial to inhibit fat *** mechanism seems to be associated with the protection of the epithelial barrier integrity and the modulation of specific bacteria in the small intestine.

关键词： Lonicera caerulea berries Polyphenols Gut microbiota Oxidative stress Intestinal epithelial barrier

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Engineered biochemical cues of regenerative biomaterials to enhance endogenous stem/progenitor cells(ESPCs)-mediated articular cartilage repair

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Bioactive Materials 2023年第8期26卷 490-512页

作者： Liangbin Zhou Jietao xu andrea Schwa Wenxue Tong Jiankun xu Lizhen Zheng Ye Li Zhuo Li Shunxiang xu Ziyi Chen Li Zou Xin Zhao Gerjo J.V.Mvan Osch Chunyi Wen Ling Qin Musculoskeletal Research Laboratory of Department of Orthopaedics and Traumatology&Innovative Orthopaedic Biomaterials and Drug Translational Research Laboratory of Li Ka Shing Institute of Health Sciences Faculty of MedicineThe Chinese University of Hong Kong999077Hong Kong SARChina Department of Biomedical Engineering Faculty of EngineeringThe Hong Kong Polytechnic University999077Hong Kong SARChina Department of Orthopaedics and Sports Medicine Erasmus MCUniversity Medical Center Rotterdam3015 GDRotterdamthe Netherlands Department of Oral and Maxillofacial Surgery Erasmus MCUniversity Medical Center Rotterdam3015 GDRotterdamthe Netherlands Centre for Regenerative Medicine and Health Hong Kong Institute of Science&InnovationChinese Academy of Sciences-CRMH999077Hong Kong SARChina Department of Biomedical Engineering Faculty of EngineeringThe Chinese University of Hong Kong999077Hong Kong SARChina Department of Otorhinolaryngology Erasmus MCUniversity Medical Center Rotterdam3015 GDRotterdamthe Netherlands Department of Biomechanical Engineering Faculty of MechanicalMaritime and Materials EngineeringDelft University of Technology(TU Delft)2600 AADelftthe Netherlands Centre for Translational Medicine Research and Development Shenzhen Institute of Advanced TechnologyThe Chinese Academy of Sciences518000ShenzhenChina

As a highly specialized shock-absorbing connective tissue,articular cartilage(AC)has very limited self-repair capacity after traumatic injuries,posing a heavy socioeconomic *** clinical therapies for small-to medium-size focal AC defects are well-developed endogenous repair and cell-based strategies,including microfracture,mosaicplasty,autologous chondrocyte implantation(ACI),and matrix-induced ACI(MACI).However,these treatments frequently result in mechanically inferior fibrocartilage,low cost-effectiveness,donor site morbidity,and short-term *** prompts an urgent need for innovative approaches to pattern a pro-regenerative microenvironment and yield hyaline-like cartilage with similar biomechanical and biochemical properties as healthy native *** regenerative biomaterials can create a favorable local environment for AC repair without causing relevant regulatory and scientific concerns from cell-based treatments.A deeper understanding of the mechanism of endogenous cartilage healing is furthering the(bio)design and application of these ***,the utilization of regenerative biomaterials to magnify the repairing effect of joint-resident endogenous stem/progenitor cells(ESPCs)presents an evolving improvement for cartilage *** review starts by briefly summarizing the current understanding of endogenous AC repair and the vital roles of ESPCs and chemoattractants for cartilage *** several intrinsic hurdles for regenerative biomaterials-based AC repair are *** recent advances in novel(bio)design and application regarding regenerative biomaterials with favorable biochemical cues to provide an instructive extracellular microenvironment and to guide the ESPCs(***,migration,proliferation,differentiation,matrix production,and remodeling)for cartilage repair are ***,this review outlines the future directions of engineering the next-generation regenerative biomaterials toward ultim

关键词： Regenerative biomaterials Endogenous stem/progenitor cells(ESPCs) Articular cartilage(AC)repair Biochemical cues

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