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1-13 Constraints on Symmetry Energy from Pygmy Resonances in 68Ni and 132Sn

IMP & HIRFL Annual Report 2010年第1期 23-25页

作者： Cao Ligang andrea carbone Gianluca Colo Dipartimento di Fisica Universit＇a degliStudi di Milano via Celoria 16 20133 Milano Italy INFN Sezione di Milano via Celoria 16 20133 Milano Italy

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68Ni和132Sn矮共振约束对称能密度依赖行为(英文)

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IMP & HIRFL Annual Report 2010年 23-25页

作者：曹李刚 andrea carbone Gianluca Colo Dipartimento di Fisica Universit`a degliStudi di Milano INFN Sezione di Milano

The energy per particle in a nuclear system characterized by a total density ρ(sum of the neutron and proton densities ρn and ρp),and by a local asymmetry δ≡(ρn-ρp)/ρ,is usually written asEA(ρ,δ)=E/A(ρ,δ=0)+ S(ρ)δ2.(1)Odd powers of δ are forbidden by the isospin symmetry and the term proportional to δ4 is found to be negligible.The above equation defines the so-called symmetry energy S(ρ).Determining the values of the symmetry energy at various densities

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4^(th) generation synchrotron source boosts crystalline imaging at the nanoscale

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Light(Science & Applications) 2022年第4期11卷 662-673页

作者： Peng Li Marc Allain Tilman A.Grunewald Marcus Rommel andrea Campos Dina carbone Virginie Chamard Aix-Marseille Univ CNRSCentrale MarseilleInstitut FresnelMarseilleFrance Nanofabrication Laboratory Department of Microtechnology and NanoscienceMC2Chalmers University of TechnologySE-41296 GothenburgSweden Aix Marseille Univ CNRSCentrale MarseilleFSCM(FR1739)CP2M13397 MarseilleFrance. MAX IV Laboratory Fotongatan 222594 LundSweden Present address:Diamond Light Source Harwell Science and Innovation CampusFermi AveDidcot OX110DEUK

New 4^(th)-generation synchrotron sources,with their increased bilince,promise to greatly improve the performances of coherent X-ray microscopy.This perspective is of major interest for crystal microscopy,which aims at revealing the 3D crystalline structure of matter at the nanoscale,an approach strongly limited by the available coherent flux.Our results,based on Bragg ptychography experiments performed at the frst 4-generation synchrotron source,demonstrate the possibility of retrieving a high-quality image of the crystalline sample,with unprecedented quality.Importantly,the larger available coherent flux produces datasets with enough information to overcome experimental limitations,such as strongly deteriorated scanning conditions.We show this achievement would not be posible with 30-generation sources,a limit that has inhibited the development of this otherwise powerful microscopy method,so far.Hence,the advent of next-generation synchrotron sources not only makes Bragg ptychography suitable for high throughput studies but also strongly relaxes the associated experimental constraints,making it compatible with a wider range of experimental set-ups at the new synchrotrons.

关键词： crystalline coherent source

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Pelvic muscle floor rehabilitation as a therapeutic option in lifelong premature ejaculation： long-term outcomes

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Asian Journal of Andrology 2018年第6期20卷 572-575页

作者： Antonio Luigi Pastore Giovanni Palleschi andrea Fuschi Yazan AI Salhi Alessandro Zucchi Giorgio Bozzini Ester Illiano Elisabetta Costantini Antonio carbone Uroiogy Unit Department of Medico-Surgical Sciences and Biotechnologies ICOT Faculty of Pharmacy and Medicine 'Sapienza' University of Rome Latina (LT) 04100 Italy Uroresearch Nonprofit Association for Research in Urology Latina 04100 Italy Department of Urology and Andrology University of Perugia Perugia 05156 Italy Department of Urology MATER DOMINI Humanitas Castellanza (VA) 21053 Italy

The aim of the study was to evaluate the long-term outcomes of pelvic floor muscle （PFM） rehabilitation in males with lifelong premature ejaculation （PE）, using intravaginal ejaculatory latency time （IELT） and the self-report Premature Ejaculation Diagnostic Tool （PEDT） as primary outcomes. A total of 154 participants were retrospectively reviewed in this study, with 122 completing the training protocol. At baseline, all participants had an IELT 〈60 s and PEDT score 〉11. Participants completed a 12-week program of PFM rehabilitation, including physio-kinesiotherapy treatment, electrostimulation, and biofeedback, with three sessions per week, with 20 min for each component completed at each session. The effectiveness of intervention was evaluated by comparing the change in the geometric mean of IELT and PEDT values, from baseline, at 3, 6, and 12 months during the intervention, and at 24 and 36 months postintervention, using a paired sample 2-tailed t-test, including the associated 95% confidence intervals. Of the 122 participants who completed PFM rehabilitation, 111 gained control of their ejaculation reflex, with a mean IELT of 161.6 s and PEDT score of 2.3 at the 12-week endpoint of the intervention, representing an increase from baseline of 40.4 s and 17.0 scores, respectively, for IELT and PEDT （P 〈 0.0001）. Of the 95 participants who completed the 36-month follow-up, 64% and 56% maintained satisfactory eiaculation control at 24 and 36 months oostintervention, respectively.

关键词： biofeedback electrostimulation intravaginal ejaculatory latency time pelvic floor rehabilitation premature ejaculation premature ejaculation diagnostic tool

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Layered enhancement at magnetic resonance enterography in inflammatory bowel disease: A meta-analysis

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World Journal of Gastroenterology 2019年第31期25卷 4555-4566页

作者： Davide Bellini Flaminia Rivosecchi Nicola Panvini Marco Rengo Damiano Caruso Iacopo carbone Riccardo Ferrari Pasquale Paolantonio andrea Laghi Department of Radiological Sciences Oncology and Pathology"Sapienza"University of RomeI.C.O.T.HospitalLatina 04100Italy Department of Surgical and Medical Sciences and Translational Medicine “Sapienza”-University of RomeSant'Andrea University HospitalAOU Sant’AndreaRome 00189Italy Department of Emergency Radiology San Camillo-Forlanini HospitalRome 00152Italy Department of Radiology San Giovanni HospitalRome 00184Italy

BACKGROUND Documentation of disease activity in patients affected by Crohn’s disease(CD)is mandatory in order to manage patients properly.Magnetic resonance imaging(MRI)is considered the reference cross-sectional technique for the assessment of CD activity.Among MRI findings,layered pattern(LP)of contrast enhancement seems to be one of the most significant signs of severe disease activity;however,it has also been associated with chronic disease and mural fibrosis.AIM To systematically evaluate the accuracy of LP of contrast enhancement in the diagnosis of active inflammation in patients with CD.METHODS In February 2019,we searched the MEDLINE and Cochrane Central Register of Controlled Trials databases for studies evaluating the diagnostic accuracy of LP of contrast enhancement on MRI for the detection of active inflammation in patients with CD.To be included,studies had to use histopathologic analysis(endoscopy or surgery)as the reference standard.Risk of bias and applicability concerns of the included studies were evaluated by using items from the Quality Assessment for Diagnostic Accuracy Studies 2(QUADAS-2)tool.Pooled sensitivity and specificity were determined using a bivariate random-effect model.Heterogeneity was quantified by using the I2 statistic.Our meta-analysis received no funding,and the review protocol was not published or registered in advance.RESULTS Of the 1383 studies identified,five articles were finally selected for quantitative and qualitative synthesis(245 patients,238 of whom had histopathologically confirmed CD,144 with active inflammation and 94 with inactive disease).The meta-analysis showed a pooled sensitivity of 49.3%(95%CI:41%-57.8%;I2:90.7%)and specificity of 89.1%(95%CI:81.3%-94.4%;I^2:48.6%).Pooled PLR and NLR were 3.3(95%CI:1.9-5.7;I2:6.1%)and 0.6(95%CI:0.5-0.9;I2 70.5%),respectively.SDOR was 6.8(95%CI:2.6-17.6;I2:27.1%).The summary ROC curve showed an area under the curve(AUC)of 0.82(SE 0.06;Q*0.76).High risk of bias and applicability concerns were observed in the domains of pa

关键词： Crohn’s disease Diagnostic imaging Magnetic resonance imaging Inflammation Fibrosis Sensitivity and specificity Meta-analysis

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Magnetic resonance imaging after anterior cruciate ligament reconstruction:A practical guide

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World Journal of Orthopedics 2016年第10期7卷 638-649页

作者： Alberto Grassi James R Bailey Cecilia Signorelli Giuseppe carbone Andy Tchonang Wakam Gian andrea Lucidi Stefano Zaffagnini Laboratorio di Biomeccanica ed Innovazione Tecnologica Istituto Ortopedico Rizzoli Department of Orthopaedic Surgery Duke Sports Sciences Institute Duke University Medical Center Unita’ Operativa di Ortopedia Dipartimento Rizzoli-Sicilia

Anterior cruciate ligament(ACL) reconstruction is one of the most common orthopedic procedures performed worldwide. In this regard, magnetic resonance imaging(MRI) represents a useful pre-operative tool to confirm a disruption of the ACL and to assess for potential associated injuries. However, MRI is also valuable postoperatively, as it is able to identify, in a non-invasive way, a number of aspects and situations that could suggest potential problems to clinicians. Graft signal and integrity, correct tunnel placement, tunnel widening, and problems with fixation devices or the donor site could all compromise the surgical outcomes and potentially predict the failure of the ACL reconstruction. Furthermore, several anatomical features of the knee could be associated to worst outcomes or higher risk of failure. This review provides a practical guide for the clinician to evaluate the post-surgical ACL through MRI, and to analyze all the parameters and features directly or indirectly related to ACL reconstruction, in order to assess for normal or pathologic conditions.

关键词： Anterior cruciate ligament reconstruction Magnetic resonance imaging Graft Tunnel Failures Complications Anatomic

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Clear cell adenocarcinoma of the colon is a unique morphological variant of intestinal carcinoma:Case report with molecular analysis

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World Journal of Gastroenterology 2008年第42期14卷 6575-6577页

作者： Marta Barisella andrea Lampis Federica Perrone Antonino carbone Anathomic Pathology Department of Pathology Fondazione IRCCS Istituto Nazionale dei Tumori Milano 20133 Italy Experimental Molecular Pathology Department of Pathology Fondazione IRCCS Istituto Nazionale dei Tumori Milano 20133 Italy

Here we report a new case of clear cell adenocarcinoma (CCA) of the colon in a 54-year-old Caucasian man. Despite of the previous reported cases, the lesion was located in the right colon and was not associated with the conventional adenoma. We performed immunohistochemical and molecular analyses in order to explore whether the CCA had the molecular features generally associated with conventional colorectal carcinoma. The immunohistochemical and molecular analyses showed that the different morphology of CCA does not reflect a distinct biological entity but only an unusual morphological variant of intestinal carcinoma.

关键词：透明细胞癌结肠癌形态变化分子分析

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Multimodality imaging in COVID-19 patients:A key role from diagnosis to prognosis

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World Journal of Radiology 2020年第11期12卷 261-271页

作者： Antonello D'andrea Juri Radmilovic Andreina carbone Alberto Forni Ercole Tagliamonte Lucia Riegler Biagio Liccardo Fabio Crescibene Cesare Sirignano Giovanna Esposito Eduardo Bossone Department of Cardiology Chair of Cardiology–Luigi Vanvitelli University–Monaldi Hospital-Association of Operating Room Nurses Ospedali Dei Colli–NaplesNaples 80131Italy Department of Cardiology and Intensive Coronary Unit “Umberto I”HospitalNocera Inferiore 84014SalernoItaly Department of Cardiology University of Campania“Luigi Vanvitelli”Monaldi HospitalNaples 80131Italy M.Scarlato COVID Hospital Scafati HospitalScafati 84018Italy Institute of Biostructures and Bioimaging of National Research Council National research CouncilNaples 80145Italy Division of Cardiology Cardarelli HospitalNaples 80131Italy

The integrated clinical,laboratory and ultrasound approach is essential for the diagnosis,evaluation and monitoring of the patient's therapy in coronavirus disease 2019 pneumonia.The ideal imaging approach in this context is not yet well defined.Chest X-ray is characterized by low sensitivity in identifying earlier lung changes.The"bedside"pulmonary ultrasound has an undeniable series of advantages in the patient at high infectious risk and can provide incremental data in the respiratory intensive care for the serial control of the individual patient as well as for the home delivery of the stabilized subjects.Pulmonary computed tomography shows high sensitivity but should not be routinely performed in all patients,because in the first 48 h it can be absolutely negative and in the late phase the imaging findings may not change the therapeutic approach.Echocardiography should be limited to patients with hemodynamic instability to assess ventricular function and pulmonary pressures.

关键词： COVID-19 Interstitial pneumonia Pulmonary computed tomography Echocardiography Lung ultrasound Thromboembolism

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Cardiac damage in athlete's heart: When the “supernormal” heart fails!

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World Journal of Cardiology 2017年第6期9卷 470-480页

作者： Andreina carbone Antonello D’andrea Lucia Riegler Raffaella Scarafile Enrica Pezzullo Francesca Martone Raffaella America Biagio Liccardo Maurizio Galderisi Eduardo Bossone Raffaele Calabrò Second University of Naples Monaldi HospitalAORN Ospedali dei Colli Department of Advanced Biomedical Sciences FedericoⅡUniversity Hospital Department of Cardiology and Cardiac Surgery University Hospital San Giovanni di Dio

Intense exercise may cause heart remodeling to compensate increases in blood pressure or volume by increasing muscle mass. Cardiac changes do not involve only the left ventricle, but all heart chambers. Physiological cardiac modeling in athletes is associated with normal or enhanced cardiac function, but recent studies have documented decrements in left ventricular function during intense exercise and the release of cardiac markers of necrosis in athlete's blood of uncertain significance. Furthermore, cardiac remodeling may predispose athletes to heart disease and result in electrical remodeling, responsible for arrhythmias. Athlete's heart is a physiological condition and does not require a specific treatment. In some conditions, it is important to differentiate the physiological adaptations from pathological conditions, such as hypertrophic cardiomyopathy, arrhythmogenic dysplasia of the right ventricle, and non-compaction myocardium, for the greater risk of sudden cardiac death of these conditions. Moreover, some drugs and performance-enhancing drugs can cause structural alterations and arrhythmias, therefore, their use should be excluded.

关键词：运动员心心脏的损坏纤维变性强烈锻练正确的室的 Arrhythmogenic 发育异常 Atrial 纤维性颤动做 Anabolic-androgenic 类固醇 Hypertrophic 心肌症

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Adoptive transfer of IL-10^(+) regulatory B cells decreases myeloid-derived macrophages in the central nervous system in a transgenic amyotrophic lateral sclerosis model

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Cellular & Molecular Immunology 2018年第7期15卷 727-730页

作者： andrea Pennati Seneshaw Asress Jonathan D Glass Jacques Galipeau Department of Medicine University of Wisconsin School of Medicine and Public Health and University of Wisconsin Carbone Cancer CenterMadisonWI 53706USA Department of Neurology Emory UniversityAtlantaGA 30322USA

I mmunosuppressive therapies have meaningful effects on the treatment of multiple sclerosis(MS),a classical inflammatory autoimmune disease of the central nervous system.1 In mice with experimental autoimmune encephalomyelitis(EAE),a murine model of human MS,we showed that an adoptive transfer of GM-CSF and Interleukin-15 Fusion Transgene(GIFT15)-derived regulatory B cells(GIFT15 Bregs)sustained a durable remission of the disease.2,3 These regulatory B cells require the expression of MHC class II and IL-10 for suppressive activity.

关键词： sustained sclerosis autoimmune

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