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Palaeogeography of a shallow carbonate platform:The case of the Middle to Late Oxfordian in the Swiss Jura Mountains

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Journal of Palaeogeography 2015年第3期4卷 251-268页

作者： andré Strasser Bernard Pittet wolfgang Hug Department of Geosciences University of Fribourg Université Lyon 1 UMR CNRS LGLTPE 5276Campus DouaBatiment Géode69622 VilleurbanneFrance Paléontologie A16 Section d'archéologie et paléontologieOffice de la cultureH?tel des Halles2900 PorrentruySwitzerland

The Oxfordian （Late Jurassic） carbonate-dominated ptatform outcropping in the Swiss Jura Mountains offers a good biostratigraphic, sequence-stratigraphic, and cyclostratigraphic framework to reconstruct changes in facies distribution at a time-resolution of 100 ka. It thus allows interpreting the dynamic evolution of this platform in much more detail than conventional palaeogeographic maps permit. As an example, a Middle to Late Oxfordian time slice is presented, spanning an interval of about 1.6 Ma. The study is based on 12 sections logged at cm-scale. The interpreted depositional environments include marginal-marine emerged ;ands, fresh-water lakes, tidal fiats, shallow lagoons, ooid shoals, and coral reefs. Although limestones dominate, marly intervals and dolomites occur sporadically. Major facies shifts are related to m-scale sea-level changes linked to the orbital short eccentricity cycle （100 ka）. The 20-ka precession cycle caused minor facies changes but cannot always be resolved. Synsedimentary tectonics induced additional accommodation changes by creating shallow basins where days accumulated or highs on which shoals or islands formed. Autocyclic processes such as lateral migration of ooid and bioclastic shoals added to the sedimentary record. CEimate changes intervened to control terrestrial run-off and, consequently, siliciclastic and nutrient input. Coral reefs reacted to such input by becoming dominated by microbialites and eventually by being smothered. Concomitant occurrence of siliciclastics anddolomite in certain intervals further suggests that, at times, it was relatively arid in the study area but there was rainfall in more northern latitudes, eroding the Hercynian substrate. These examples from the Swiss Jura demonstrate the highly dynamic and （geologically speaking） rapid evolution of sedimentary systems, in which tectonically controlled basin morphology, orbitally induced climate and sea-level changes, currents, and the ecology of the carbon

关键词： Swiss Jura Oxfordian carbonate platform facies evotution sequence stratigraphy cyclostratigraphy

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Sliding response of gravity dams including vertical seismic accelerations

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Earthquake Engineering and Engineering Vibration 2003年第2期2卷 189-200页

作者： Constantin Christopoulos PierreLéger andré Filiatrault Department of Civil Engineering University of TorontoCanada Assistant Professor Department of Civil Engineering Ecole PolytechniqueMontrealCanada Professor Department of Civil Structural and Environmental EngineeringUniversity at BuffaloUSA Professor

Seismic safety assessment of gravity dams has become a major concern in many regions of the world while the effects of vertical seismic accelerations on the response of structures remain poorly *** paper first investigates the effect of including vertical accelerations in the sliding response analysis of gravity dams subjected to a range of historical ground motion records separated in two groups according to their source-to-site *** showed that the incidence of vertical accelerations on the sliding response of gravity dams is significantly higher for near-source records than for far- source *** pseudo-static 30% load combination rule,commonly used in practice to account for the non-simultaneous occurrence of the peak horizontal and vertical accelerations,yielded good approximations of the minimum safety factors against sliding computed from time-history analyses.A method for empirically estimating the vertical response spectra based on horizontal spectra,accounting for the difference in frequency content and amplitudes between the two components is *** from analyses using spectrum compatible horizontal and vertical synthetic records also approximated well the sliding response of a gravity dam subjected to series of simultaneous horizontal and vertical historical earthquake records.

关键词： vertical accelerations sliding gravity dams synthetic accelerograms pseudo-static combinations frequency

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Novel electrocardiographic dyssynchrony criteria that may improve patient selection for cardiac resynchronization therapy

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Journal of Geriatric Cardiology 2022年第1期19卷 31-43页

作者： Gábor Katona andrás Vereckei Department of Medicine and Hematology Semmelweis UniversityBudapestHungary

Cardiac resynchronization therapy(CRT)is an evidence-based effective therapy of symptomatic heart failure with reduced ejection fraction refractory to optimal medical treatment associated with intraventricular conduction disturbance,that results in electrical dyssynchrony and further deterioration of systolic ventricular ***,the non-response rate to CRT is still 20%−40%,which can be decreased by better patient *** main determinant of CRT outcome is the presence or absence of significant ventricular dyssynchrony and the ability of the applied CRT technique to eliminate *** current guidelines recommend the determination of QRS morphology and QRS duration and the measurement of left ventricular ejection fraction for patient selection for ***,QRS morphology and QRS duration are not perfect indicators of electrical dyssynchrony,which is the cause of the not negligible non-response rate to CRT and the missed CRT implantation in a significant number of patients who have the appropriate substrate for *** imaging modalities,many ventricular dyssynchrony criteria were devised for the detection of mechanical dyssynchrony,but their utility in patient selection for CRT is not yet proven,therefore their use is not recommended for this ***,CRT can eliminate only mechanical dyssynchrony due to underlying electrical dyssynchrony,for this reason ECG has a greater role in the detection of ventricular dyssynchrony than imaging *** improve assessment of electrical dyssynchrony,we devised two novel ECG dyssynchrony criteria,which can estimate interventricular and left ventricular intraventricular dyssynchrony in order to improve patient selection for *** we discuss the results achieved by the application of these new ECG dyssynchrony criteria,which proved to be useful in predicting the CRT response in patients with nonspecific intraventricular conduction disturbance pattern(the second greatest group of CRT candidates),an

关键词： patient synchronization eliminate

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GekkoFS—A Temporary Burst Buffer File System for HPC Applications

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Journal of Computer Science & Technology 2020年第1期35卷 72-91页

作者： Marc-andréVef Nafiseh Moti Tim Süβ Markus Tacke Tommaso Tocci Ramon Nou Alberto Miranda Toni Cortes andréBrinkmann Zentrum für Datenverarbeitung Johannes Gutenberg University MainzMainz 55128Germany Barcelona Supercomputing Center Barcelona 08034Spain Computer Architecture Department Universitat Politècnica de CatalunyaBarcelona 08034Spain

Many scientific fields increasingly use high-performance computing(HPC)to process and analyze massive amounts of experimental data while storage systems in today's HPC environments have to cope with new access *** patterns include many metadata operations,small I/O requests,or randomized file I/O,while general-purpose parallel file systems have been optimized for sequential shared access to large *** buffer file systems create a separate file system that applications can use to store temporary *** aggregate node-local storage available within the compute nodes or use dedicated SSD clusters and offer a peak bandwidth higher than that of the backend parallel file system without interfering with ***,burst buffer file systems typically offer many features that a scientific application,running in isolation for a limited amount of time,does not *** present GekkoFS,a temporary,highly-scalable file system which has been specifically optimized for the aforementioned use *** provides relaxed POSIX semantics which only offers features which are actually required by most(not all)*** is,therefore,able to provide scalable I/O performance and reaches millions of metadata operations already for a small number of nodes,significantly outperforming the capabilities of common parallel file systems.

关键词： distributed file system high-performance computing(HPC) burst buffer POSIX(portable operating system interface)

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Lipid scrambling in immunology:why it is important

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Cellular & Molecular Immunology 2023年第9期20卷 1081-1083页

作者： Ning wu andréVeillette The First Affiliated Hospital of Anhui Medical University Clinical Immunology InstituteAnhui Medical UniversityHefeiAnhuiChina Laboratory of Molecular Oncology Institut de recherches cliniques de Montréal(IRCM)MontréalQC H2W1R7Canada Department of Medicine University of MontréalMontréalQC H3T 1J4Canada Department of Medicine McGill UniversityMontréalQC H3G 1Y6Canada

Asymmetric lipid distribution in the plasma membrane(PM)is one of the fundamental features of living *** not only serve as structural components of the biophysical structure of the PM that preserves cell integrity but also participate directly in *** phospholipids(PLs),such as phosphatidylserine(PS),phosphatidylethanolamine(PE),and phosphoinositol(PI),are preferentially located in the inner layer of the PM,creating electrostatic charges for the docking of membrane-associated and cytoplasmic proteins carrying polybasic stretches of amino ***,there is emerging evidence that reversible changes in the distribution of these lipids take place in the PM and that these changes are critical for normal cell signaling,functions and homeostasis[1–3].They can also be implicated in the genesis of pathologies.

关键词： electrostatic reversible distribution

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First Record of the Gekkonid Genus Cnemaspis Strauch, 1887 from Gunung Mulu National Park, Northern Sarawak, East Malaysia may Represent an Undescribed Species

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Asian Herpetological Research 2014年第3期5卷 209-212页

作者： andré KOCH Sebastian SCHULZ Zoological Research Museum Alexander Koenig (ZFMK) Leibniz-Institute for terrestrial Biodiversity

we provide confirmed photographic evidence for the previously overlooked occurrence of the polyphyletic Asian gecko genus Cnemaspis from Gunung Mulu National Park, the world-renowned UNESCO natural heritage site in northern Sarawak, East Malaysia. This new record from Sarawak province represents a remarkable range extension for Cnemaspis cf. kendallii by 550 km to the northeast and denotes the most northern occurrence of the genus in Borneo. Our new finding makes it very likely that these gekkonid lizards also inhabit appropriate limestone karst habitats in adjacent Sabah, Brunei, and Kalimantan. Given the visible differences in the Mulu specimen compared to those from the remaining distribution range on Borneo and the Malaysian Peninsula together with the fact that numerous Cnemaspis species are restricted to small areas, it seems plausible that another undescribed, rather cryptic and possibly locally endemic Bornean species is involved. Lastly, the new record contributes to the importance of the Mulu National Park as a major conservation area in East Malaysia of international concerns.

关键词： Southeast Asia Borneo Gekkonidae herpetofaunal diversity new record

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Hybrid Cellular Automaton-Parabolic Thick Needle model for equiaxed dendritic solidification

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Journal of Materials Science & Technology 2022年第29期124卷 26-40页

作者： Romain Fleurisson Oriane Senninger Gildas Guillemot Charles-andré Gandin MINES ParisTech PSL Research UniversityCEMEF UMR CNRS 7635CS1020706904 Sophia AntipolisFrance

A hybrid Cellular Automaton(CA)-Parabolic Thick Needle(PTN)model is developed for the simulation of an equiaxed dendritic *** is implemented by solving conservation equations with the Finite Element(FE)method at two *** the scale of the microstructure,dendritic branches are approximated by a network of *** solute field is computed in the liquid using a FE mesh with minimum size smaller than the diffusion length ahead of the dendrite tips,giving access to a detailed description of each dendrite tip growth velocity as well as solutal interactions between *** the simulation domain scale,volume averaged heat and solute transfers are solved on a coarser FE *** average volumetric fraction of phases is deduced from a field giving the fraction of dendritic microstructure together with a microsegregation *** the PTN themselves grow on CA cells,the dendrite tip growth velocity is transferred to the vertices of the polygon associated to the CA growth ***,the field giving the fraction of dendritic microstructure is deduced from the fraction of CA cells part of the mushy zone,which include cells containing PTN *** of the new multiple scale CAPTN model include solutal interaction between dendrite branches together with long range transfer of heat and solute mass,together with the role of latent heat release on equiaxed solidification.

关键词： Solidification Dendrite growth law Multiscale Finite element method

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Aristotle＇s Immovable Movers： A Sketch

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Frontiers of Philosophy in China 2015年第2期10卷 273-286页

作者： andré Laks Department of Philosophy Panamerican University Col. Insurgentes Mixcoac CP03920 México D.F.

In keeping with a view that is explicitly formulated by Aristotle in his Motion of Animals, general kinetic principles must be specified according to the different types of movable entities existing in the universe. At issue, essentially, are the motions of the stars and the motions of animals. whereas the cosmological immovable mover is the object of two complementary analyses （in Bk. Ⅷ of Physics and in Chs. 6 and 7 of Bk. Ⅻ of Metaphysics）, information on the immovability of the first mover responsible for animal motion is to be found in the psychological and psycho-physiological treatises （On the Soul, in Bk. Ⅰ, Chs. 3 and 4, and in Bk. Ⅲ, Ch. 10 and in Ch. 6 of the Motion of Animals）. But it is also found in Ch. 7, Bk. Ⅻ of the Metaphysics, in the very context of the argument concerning the absolutely first immovable mover of the world. This suggests that the two types of motion, that of the stars and that of animals, however distinct the arguments about them are, rest on a single scheme, and maybe even on a common principle. This is liable to surprise us, as much as stars and animals appear to us to belong to heterogeneous orders of reality. But the situation is different for Aristotle, who, as attentive as he is to differences, tends nonetheless to conceive the stars as living things of a particular kind. This fact is the source of a series of difficulties that Aristotle generously left for his many commentators to solve. Aim of this text, which was initially directed to a larger audience, is to set some of these complex issues in both simple and up to date terms.

关键词： Aristotle immovable movers final cause efficient cause soul animal motion

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Affinity Solvents for Intensified Organics Extraction: Development Challenges and Prospects

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Tsinghua Science and Technology 2006年第2期11卷 171-180页

作者： andré B. de Haan University of Twente Enschede The Netherlands

In most organics extraction processes, the commonly used solvents employ solely physical interactions. Therefore, for the recovery and purification of products from complex mixtures, the selectivity and/or capacity of classical solvents towards the desired solutes is usually insufficient, enforcing the need for complex and thus expensive separation schemes. Significant simplification and cost-reduction can be achieved when affinity solvents would be available that are able to recognize the solutes of interest by their molecular structure. The main development challenges to establish such affinity solvents are： Selection and incorporation of molecular recognition and complexation capabilities; Evaluation of extraction capabilities; Efficient re- covery and recycling of the affinity solvents; Implementation in industrial extraction equipment. This paper presents how these development challenges are addressed at the University of Twente, going all the way from affinity solvent design and synthesis, via high throughput screening and characterization up to pilot plant evaluation. Essential in the successful development of affinity solvents are structural cooperations with molecular chemists and custom synthesis companies for their design and synthesis. The various aspects are illustrated by several examples where newly developed environmentally benign affinity solvents appeared able to create major breakthroughs. The applications addressed involve oxygenates, sugars, and pharmaceutical ingredients, such as optical isomers and biomolecules.

关键词： affinity solvent organics extraction molecular recognition complexation reaction

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Penalty Algorithms in Hilbert Spaces

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Acta Mathematica Sinica,English Series 2007年第2期23卷 229-236页

作者： Jean Pierre DUSSAULT Hai SHEN andré BandrAUK Département d'Informatique Faculté des Sciences.Université de Sherbrooke Viador inc Laboratoire de Chimie Théorique Faculté des Sciences Université de Sherbrooke

we analyze the classical penalty algorithm for nonlinear programming in Hilbert spaces and obtain global convergence results, as well as asymptotic superlinear convergence order. These convergence results generalize similar results obtained for finite-dimensional problems. Moreover, the nature of the algorithms allows us to solve the unconstrained subproblems in finite-dimensional spaces.

关键词： penalty methods infinite dimensional optimization

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