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Multiple-Photon Resonance Enabled Quantum Interference in Emission Spectroscopy of N2+

Ultrafast Science 2024年第2期4卷 1-7页

作者： Xiang Zhang Qi Lu YaLei Zhu Jing Zhao Rostyslav Danylo Liang Xu Mingwei Lei Hongbing Jiang Chengyin wu Zhedong Zhang Aurélien Houard Vladimir Tikhonchuk andréMysyrowicz Qihuang Gong Songlin Zhuang Zengxiu Zhao Yi Liu Shanghai Key Lab of Modern Optical System University of Shanghai for Science and Technology.516Jungong Road200093 ShanghaiChina Department of Physics National University of Defense TechnologyChangsha 410073China Laboratoire d'Optique Appliquee ENSTA ParisEcole Polytechnique CNRSInstitut Polytechnique de Paris828 Boulevard des Marechaux91762 Palaiseau CedexFrance State Key Laboratory for Mesoscopic Physics School of PhysicsPeking UniversityBejing 100871China Department of Physics City University of Hong KongKowloonHong Kong SAR Centre Lasers Intenses et Applications University of Bordeaux-CNRS-CEA351 Cours de la Liberation33405 Talence Cedex France Extreme Light Infrastructure ERIC ELI Beamlines Facility25241 Doln BrezanyCzech Republic CAS Center for Excellence in Ultra-intense Laser Science Shanghai 201800China

Quantum interference occurs frequently in the interaction of laser radiation with materials,leading to a series of fascinating effects such as lasing without inversion,electromagnetically induced transparency,Fano resonance,*** quantum interference effects are mostly enabled by single-photon resonance with transitions in the matter,regardless of how many optical frequencies are ***,we report on quantum interference driven by multiple photons in the emission spectroscopy of nitrogen ions that are resonantly pumped by ultrafast infrared laser *** the spectral domain,Fano resonance is observed in the emission spectrum,where a laser-assisted dynamic Stark effect creates the *** the time domain,the fast-evolving emission is measured,revealing the nature of free-induction decay arising from quantum radiation and molecular *** findings clarify the mechanism of coherent emission of nitrogen ions pumped with mid-infrared pump laser and are found to be *** present work opens a route to explore the important role of quantum interference during the interaction of intense laser pulses with materials near multiple photon resonance.

关键词： pumped pump Quantum

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Interindividual Age-Independent Differences in Human CX43 Impact Ventricular Arrhythmic Risk

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Research 2024年第3期6卷 417-432页

作者： Laura García-Mendívil María Pérez-Zabalza Antoni Oliver-Gelabert JoséMaría Vallejo-Gil Javier Fañanás-Mastral Manuel Vázquez-Sancho Javier andréBellido-Morales Alexánder Sebastián Vaca-Núñez Carlos Ballester-Cuenca Emiliano Diez Laura Ordovás Esther Pueyo Biomedical Signal Interpretation and Computational Simulation group(BSICoS) Aragón Institute of Engineering ResearchUniversity of ZaragozaZaragoza 50018Spain BSICoS Instituto de Investigación Sanitaria Aragón(IISA)Zaragoza 50018Spain Centro Universitario de la Defensa(CUD) Zaragoza 50090Spain. Department of Cardiovascular Surgery University Hospital Miguel ServetZaragoza 50009Spain. Institute of Experimental Medicine and Biology of Cuyo(IMBECU) CONICETMendoza 5500Argentina. Fundación Agencia Aragonesa para la Investigación y el Desarrollo(ARAID) Zaragoza 50018Spain. Biomedical Research Networking Center in Bioengineering Biomaterials and Nanomedicine(CIBER-BBN)Zaragoza 50018Spain.

Connexin 43 (CX43) is one of the major components of gap junctions, the structures responsible for the intercellular communication and transmission of the electrical impulse in the left ventricle. There is limited information on the histological changes of CX43 with age and their effect on electrophysiology, especially in humans. Here, we analyzed left ventricular biopsies from living donors starting at midlife to characterize age-related CX43 remodeling. we assessed its quantity, degree of lateralization, and spatial heterogeneity together with fibrotic deposition. we observed no significant age-related remodeling of CX43. Only spatial heterogeneity increased slightly with age, and this increase was better explained by biological age than by chronological age. Importantly, we found that CX43 features varied considerably among individuals in our population with no relevant relationship to age or fibrosis content, in contrast to animal species. we used our experimental results to feed computational models of human ventricular electrophysiology and to assess the effects of interindividual differences in specific features of CX43 and fibrosis on conduction velocity, action potential duration, and arrhythmogenicity. we found that larger amounts of fibrosis were associated with the highest arrhythmic risk, with this risk being increased when fibrosis deposition was combined with a reduction in CX43 amount and/or with an increase in CX43 spatial heterogeneity. These mechanisms underlying high arrhythmic risk in some individuals were not associated with age in our study population. In conclusion, our data rule out CX43 remodeling as an age-related arrhythmic substrate in the population beyond midlife, but highlight its potential as a proarrhythmic factor at the individual level, especially when combined with increased fibrosis.

关键词： CX43 rhythm Independent

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Imaging-based prediction of hepatocellular carcinoma recurrence after microwave ablation as bridge therapy: A glimpse into the future

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world Journal of Transplantation 2024年第4期14卷 1-5页

作者： Cristian Lindner Rodrigo San Martín andrés Concha David Clemo Jorge Valenzuela Department of Radiology Faculty of MedicineUniversity of ConcepciónConcepción 4030000Chile Department of Radiology Hospital Regional Guillermo Grant BenaventeConcepción 4030000BiobíoChile

Liver transplantation(LT)remains the treatment of choice for early-stage hepato-cellular carcinoma(HCC)and offers the best long-term oncological ***,the increasing waiting list for LT has led to a significant dropout rate as patients experience tumor progression beyond the Milan ***,locoregional therapies,such as microwave ablation(MwA),have emerged as promising bridge treatments for patients awaiting *** therapies have shown promising results in preventing tumor progression,thus reducing the dropout rate of LT *** the efficacy of MwA in treating HCC,tumoral recurrence after ablation remains a major challenge and significantly impacts the prognosis of HCC ***,accurately diagnosing tumoral recurrence post-ablation is *** studies have developed novel imaging features based on magnetic resonance imaging of HCC,which could provide essential information for predicting early tumoral recurrence after *** advancements could address this unresolved challenge,improving the clinical outcomes of patients on the LT waiting *** article explored the current landscape of MwA as a bridge therapy for HCC within the Milan criteria,high-lighting the emerging role of novel imaging-based features aimed at improving the prediction of tumor recurrence after MwA.

关键词： Liver transplantation Hepatocellular carcinoma Ablation techniques Multiparametric magnetic resonance imaging Interventional oncology Liver disease Microwaves

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Changes in calcium accumulation and utilization efficiency and their impact on recycling,immobilization,and export across the oil palm cycle

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Oil Crop Science 2024年第3期9卷 143-150页

作者： Ismael de Jesus Matos Viégas Luma Castro de Souza Eric Victor de Oliveira Ferreira Milton Garcia Costa Glauco andré dos Santos Nogueira Vitor Resende do Nascimento Candido Ferreira de Oliveira Neto Capanema Campus Federal Rural University of the Amazon(UFRA)Av.Barao de CapanemaCaixa D'agua5514-6434ParaBrazil Center of Agricultural and Environmental Sciences Federal University of Maranhao(UFMA)ChapadinhaBR-222km 04SNBoa Vista65500000MaranhaoBrazilc Capitao Poço Campus Federal Rural University of the Amazon(UFRA)Tv.Pau AmareloS/n-Vila Nova68650-000Capitao PoçoParaBrazil Department of Soil Science Sao Paulo State University(Unesp)School of Agricultural and Veterinarian SciencesJaboticabalVia de Acesso Prof.Paulo Donato CastelaneCastellane-S/N-Vila Industrial14884-900Sao PauloBrazil Institute of Agricultural Sciences(ICA) Federal Rural University of the Amazon(UFRA)Estr.Principal da Ufra2150Curio-Utinga66077-580BelemParaBrazil

Effective calcium(Ca)management is crucial for optimizing oil palm cultivation and enhancing crop *** study aimed to gain insights into the dynamics of Ca concentration,accumulation,exportation,immobilization,and recycling in various oil palm organs relative to plant *** experiment was conducted at the Agropalma enterprise site in the northeastern region of Para State,Brazil,evaluating seven plant age treatments:2,3,4,5,6,7,and 8 years *** a completely randomized design with four *** results demonstrated an age-related increase in Ca concentration in petioles,rachis,arrows,male inflorescences,peduncles,and ***,Ca accumulation exhibited an upward trend in all organs with progressing plant ***,the study revealed an enhanced Ca use efficiency across all plant organs in correlation with the age of oil palm *** findings underscore the dynamic nutritional demands of oil palm,influencing Ca immobilization,cycling,and export throughout its developmental stages.

关键词： Elaeis guineensis Jacq Ca cycling Ca export Ca immobilization Ca use efficiency Plant nutrition Amazon

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Efficient fidelity estimation:alternative derivation and related applications

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Communications in Theoretical Physics 2024年第9期76卷 16-20页

作者： Diego S Starke Marcos L w Basso Jonas Maziero Physics Department Center for Natural and Exact SciencesFederal University of Santa MariaRoraima Avenue 1000Santa MariaRS97105-900Brazil Center for Natural and Human Sciences Federal University of ABCAvenue of the StatesSanto AndréSão Paulo09210-580Brazil

In[***.A 107012427(2023)],Baldwin and Jones prove that Uhlmann–Jozsa’s fidelity between two quantum statesρandσ,i.e.,F(ρ,σ)=(Tr√√ρσ√ρ)^(2),can be written in a simplified form as F(ρ,σ)=(Tr√ρσ)^(2).In this article,we give an alternative proof of this result,using a function power series expansion and the properties of the trace *** approach not only reinforces the validity of the simplified expression but also facilitates the exploration of novel dissimilarity functions for quantum states and more complex trace functions of density operators.

关键词： Ulhmann–Jozsa fidelity Rényi entropy efficient fidelity estimation Chebyshev polynomials

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Sexual dimorphism in the antitumor immune responses elicited by the combination of fasting and chemotherapy

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Cancer Communications 2024年第4期44卷 508-513页

作者： andrés Pastor-Fernández Manuel Montero Gómez de las Heras Jose Ignacio Escrig-Larena Marta Barradas Cristina Pantoja Adrian Plaza Jose Luis Lopez-Aceituno Esther Durán Alejo Efeyan Maria Mittelbrunn Lola Martinez Pablo Jose Fernandez-Marcos Metabolic Syndrome Group(BIOPROMET) Madrid Institute for Advanced Studies(IMDEA)FoodE28049MadridSpain Molecular Biology Center Severo Ochoa(CBMSO) Spanish National Research Council(CSIC)Madrid Autonoma University(UAM)MadridSpain Department of Basic Medical Sciences Institute of Applied Molecular MedicineSchool of MedicineUniversity Studies Center(CEU)-San Pablo UniversityMadridSpain Metabolism and Cell Signaling Laboratory Spanish National Cancer Research Centre(CNIO) MadridSpain 5Flow Cytometry UnitBiotechnology ProgrammeSpanish National Cancer Research Centre(CNIO)MadridSpain

Fasting reduces chemotherapy toxicity[1],enhances immunogenic tumor cell death[2,3]and increases CD8^(+)T cell infiltration in tumors,particularly when combined with chemotherapy[2,3]or immunotherapy[4].More-over,fast... 详细信息

关键词： chemotherapy fasting immune

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有限域上方程的解数

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数学译林 2024年第2期43卷 97-104页

作者： andré weil 王奔阳(译) 林开亮(校) 不详

本文要考虑的方程形如a_(0)x_(0)^(n_(0))+a_(1)x_(1)^(n_(1))+… +a_(r)x_(r)^(n_(r))=b. (1)这类方程有着很有趣的历史.在《算术探索(Disquisitiones)》的第358目[1a]中,Gauss(高斯)对形如p=3n+1的素数定出了三阶的Gauss和(即所谓的... 详细信息

关键词： Gauss和同余式类方程有限域方程的解数分圆素数

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Determinants of the Low Proportion of Pregnant women Seen for First-Trimester Prenatal Care at KoudougouUrban Medical Center, Burkina-Faso

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Open Journal of Nursing 2024年第8期14卷 421-432页

作者： Swanfani Talardia andré Thiombiano Nestor Bationo Ziemlé Clément Meda Iliassa Sawadogo Léa Yameogo Cécile Sanou Dieudonné Soubeiga Institut de Formation et de Recherche Interdisciplinaire en Science de la Sant et de lEducation (IFRISSE) Ouagadougou et Ecole Nationale de Sant Publique (ENSP) Bobo-Dioulasso Burkina Faso Department of Public Health Universit Joseph Ki-ZERBO Ouagadougou Burkina-Faso Institut supRieur des Sciences de la Sant (INSSA) de lUniversit Nazi Boni et Centre Hospitalier Universitaire Souro Sanou (CHUSS) Bobo Dioulasso Burkina Faso Direction Rgionale de la Sant et de lHygine Publique des Hauts Bassins Bobo Dioulasso Burkina Faso Direction Rgionale de la Sant et de lHygine Publique du Centre Ouest Koudougou Burkina Faso Ecole Nationale de Sant Publique Direction Rgionale de Bobo-Dioulasso Bobo-Dioulasso Burkina Faso

Introduction: Antenatal care (ANC) contributes to the reduction of maternal and neonatal morbidity and mortality. The study aimed to investigate the determinants of the low proportion of pregnant women seen for first antenatal care in the first trimester of pregnancy at the urban medical center of Koudougou, Burkina Faso. Materials and Methods: This was a cross-sectional study with data collection from June 08 to August 18, 2021. It involved a sample of 302 participants including 280 pregnant women and 22 maternity providers. Semi-structured individual interviews, non-participant observation, and a literature review were used. Results: Pregnant women age 20 and over, knowledge of the date of their last menstrual period, and knowledge of the antenatal care calendar were associated with coming into contact (1) with Antenatal care in the first trimester of pregnancy. In addition, there was a lack of availability of antenatal care services, inadequate reception of clients, and shortages of health products. Conclusion: There is a need to revisit strategies for communicating with women about ANC, reorganizing ANC services, and improving ANC services.

关键词： Least Risk Maternity Maternal and Neonatal Health Maternal and Neonatal Mortality Maternal and Neonatal Morbidity Reception

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当代中国人群牙齿可观测特征的多样性研究

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基因组学与应用生物学 2024年第1期43卷 150-171页

作者：罗浩陈颖洁杨光睿 Kaustubh Adhikari 夏斌 andrés Ruiz-Linares Miguel Delgado 复旦大学生命科学学院现代人类学教育部重点实验室人类遗传学与人类学系开放大学科学技术工程和数学学院数学与统计学院北京大学口腔医学院拉普拉塔国立大学自然科学及博物馆学院人类学科

本研究基于当代中国人群3D牙齿模型数据，参照拉美人群进化和多样性研究联合会(consortium for the analysis of the diversity and evolution of Latin America, CANDELA)所使用的牙齿特征点标记方法，使用牙齿特征点间的欧几里得线性... 详细信息

本研究基于当代中国人群3D牙齿模型数据，参照拉美人群进化和多样性研究联合会(consortium for the analysis of the diversity and evolution of Latin America, CANDELA)所使用的牙齿特征点标记方法，使用牙齿特征点间的欧几里得线性距离(Euclidean linear distances, ELD)表示的牙齿表型作为牙齿可观测特征的度量，探究个体因素(年龄、性别)和群体因素(民族)对当代中国人群牙齿可观测特征多样性的影响。通过对牙齿标记特征点的典型变量分析(canonical variate analysis, CVA)、交叉验证(cross validation, CV)、主成分分析(principal component analysis, PCA)以及对牙齿表型的Pearson相关性分析和差异分析，本研究发现进化上相近的群体牙齿可观测特征往往更接近。具体来说，汉族的上颌牙齿可观测特征和壮族、苗族较为接近而不同于蒙古族的，而藏族的上、下颌牙齿可观测特征不同于维吾尔族的；南北中汉族牙齿表型的差异具有明确的方向性，下颌牙齿差异比上颌更明显；从性别角度看，男女牙齿表型差异主要体现在尖牙上，男性尖牙平均宽度和高度显著大于女性的；对不同年龄群体的差异分析表明，遗传外因素对牙齿可观测特征的影响主要体现在尖牙、上颌第一磨牙、下颌第一前磨牙上。

关键词：当代中国人群牙齿可观测特征表型差异

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Pathogenesis and clinical features of severe hepatitis E virus infection

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world Journal of Virology 2024年第2期13卷 19-33页

作者： László Orosz Károly Péter Sárvári Áron Dernovics andrás Rosztóczy Klára Megyeri Department of Medical Microbiology University of SzegedSzeged 6720Csongrád-CsanádHungary Department of Internal Medicine Division of GastroenterologyUniversity of SzegedSzeged 6725Csongrád-CsanádHungary

The hepatitis E virus(HEV),a member of the Hepeviridae family,is a small,non-enveloped icosahedral virus divided into eight distinct genotypes(HEV-1 to HEV-8).Only genotypes 1 to 4 are known to cause diseases in *** 1 and 2 commonly spread via fecal-oral transmission,often through the consum-ption of contaminated *** 3 and 4 are known to infect pigs,deer,and wild boars,often transferring to humans through inadequately cooked *** hepatitis caused by HEV in healthy individuals is mostly asymptomatic or associated with minor symptoms,such as ***,in immunosup-pressed individuals,the disease can progress to chronic hepatitis and even escalate to *** pregnant women,an HEV infection can cause fulminant liver failure,with a potential mortality rate of 25%.Mortality rates also rise amongst cirrhotic patients when they contract an acute HEV infection,which can even trigger acute-on-chronic liver failure if layered onto pre-existing chronic liver *** the prevalence of HEV infection continues to rise worldwide,highlighting the particular risks associated with severe HEV infection is of major medical *** text offers a brief summary of the characteristics of hepatitis developed by patient groups at an elevated risk of severe HEV infection.

关键词： Hepatitis E virus Cirrhosis Acute-on-chronic liver failure Pregnancy Immune dysfunction Open reading frames 1-4

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