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Wound healing activity of Ullucus tuberosus,an Andean tuber crop

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Asian Pacific Journal of Tropical Biomedicine 2017年第6期7卷 538-543页

作者： Nathalie Heil Karent Bravo andrés Montoya sara Robledo Edison Osorio Grupo de Investigación en sustancias Bioactivas Facultad de Ciencias Farmacéuticas y AlimentariasUniversidad de Antioquia PECET–Medical Research Institute School of MedicineUniversity of Antioquia

Objective:This study was designed to investigate the wound healing activity of aqueous extracts of Ullucus tuberosus(***) using in vitro ***:Lyophilized pulp and acetone extracts of *** were produced using ultrasound *** capacity for collagenase activation was evaluated using fluorescence detection of the enzymatic ***,the influence of *** extracts on cell proliferation,cell migration and synthesis of the extracellular matrix(ECM)proteins,metalloproteinase(MMP-1) and pro-collagen was analyzed using human dermal fibroblasts in ***:An increase in collagenase activity of 12% supports the utility of *** as an agent for scar *** addition,the extracts showed an increase in the proliferation and migration of human dermal fibroblasts and the production of pro-collagen and MMP-1 after treatment with *** *** increase in proliferation,migration and pro-collagen levels positively influenced the regeneration of scarless tissue during the proliferation phase,whereas the increase in MMP-1 may have favored the wound healing process during the remodeling and cellular differentiation ***:The results of this study show for first time that *** is a promising candidate to support scarless tissue regeneration.

关键词： Wound healing Collagenase Pro-collagen MMP-1 Ullucus tuberosus

Parallel droplet microfluidics for high throughput cell encapsulation and synthetic microgel generation

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Microsystems & Nanoengineering 2018年第1期4卷 525-533页

作者： Devon M.Headen JoséR.García andrés J.García Woodruff school of Mechanical Engineering Georgia Institute of TechnologyAtlantaGA 30332USA Petit Institute for Bioengineering and Biosciences Georgia Institute of TechnologyAtlantaGA 30332USA

Cells can be microencapsulated in synthetic hydrogel microspheres(microgels)using droplet microfluidics,but microfluidic devices with a single droplet generating geometry have limited throughput,especially as microgel diameter *** we demonstrate microencapsulation of human mesenchymal stem cells(hMsCs)in small(o100μm diameter)microgels utilizing parallel droplet generators on a two-layer elastomer device,which has 600% increased throughput ***-nozzle *** of microgel diameters were compared between products of parallel ***-nozzle configurations for two square nozzle widths,35 and 100μ*** produced on parallel nozzles were equivalent to those produced on single nozzles,with substantially the same *** of hMsCs was compared for parallel nozzle devices of each *** five micrometer wide nozzle devices could be operated at twice the cell concentration of 100μm wide nozzle devices but produced more empty microgels than predicted by a Poisson *** micrometer wide nozzle devices produced microgels as predicted by a Poisson *** of microgels did not increase with the addition of cells for either nozzle *** encapsulated on 35μm wide nozzle devices had reduced viability(~70%)and a corresponding decrease in vascular endothelial growth factor(VEGF)secretion compared to hMsCs cultured on tissue culture(TC)*** hMsCs using 100μm wide nozzle devices mitigated loss of viability and function,as measured by VEGF secretion.

关键词： droplets microencapsulation microgel multilayer parallel

Management of biliary complications after orthotopic liver transplantation:The role of endoscopy

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World Journal of Gastroenterology 2008年第4期14卷 493-497页

作者： Maria C Londoo Domingo Balderramo andrés Cárdenas GI Unit Institut de Malalties Digestives i MetaboliquesUniversity of BarcelonaHospital ClínicBarcelona 08036Spain

Biliary complications are signifi cant causes of morbidity and mortality after orthotopic liver transplantation (OLT). The estimated incidence of biliary complications after OLT ranges between 10%-25%,however,these numbers continue to decline due to improvement in surgical techniques. The most common biliary complications are strictures (both anastomotic and non-anastomotic) and bile leaks. Most of these problems can be appropriately managed with endoscopic retrograde colangiography (ERC). Other complications such as bile duct stones,bile casts,sphincter of Oddi dysfunction,and hemobilia,are less frequent and also can be managed with ERC. This article will review the risk factors,diagnosis,and endoscopic management of the most common biliary complications after OLT.

关键词： Encoscopic retrograde cholangiopancreatography Orthotopic liver transplantation Biliarystrictures Bile leaks

Hard life for sons in the nest?sex-dependent offspring mortality in Great Tits in urban and forest areas

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Avian Research 2024年第1期15卷 91-97页

作者： Nora Agh Henriett Anna Dalvári Krisztián szabó Ivett Pipoly andrás Liker HUN-REN-PE Evolutionary Ecology Research Group University of PannoniaH-8200VeszpremPf.1158.Hungary Behavioral Ecology Research Group Center for Natural SciencesUniversity of PannoniaH-8200Pf.1158.VeszpremHungary Molecular Ecology Research Group Department of EcologyUniversity of Veterinary Medicine BudapestH-1400Pf.2.BudapestHungary synlab Hungary Ltd. H-1211Weiss Manfr´ed Str.5-7BudapestHungary

sex-biased mortality can occur in birds during development,for example due to sexual differences in energy requirement and/or environmental sensitivity,or the effects of sex hormones or sex differences in the expression of mutations linked to sex *** extent of sex-bias in mortality may also be related to environmental conditions that influence offspring development and *** areas often provide poorer conditions for nestling development resulting in higher offspring mortality compared to natural areas,which may accelerate sex differences in offspring mortality in *** test this hypothesis,we examined the sex ratio of dead offspring in Great Tits(Parus major),using 427 samples of unhatched eggs and dead nestlings collected in two urban and two forest sites between 2013 and *** ratio of males in the whole sample of dead offspring(56.9%)was significantly higher than expected by an 1:1 ratio,and the strongest sex biases were detected in urban areas(57.6%males)and in young nestlings(s old,59.0%males).However,the sex ratios of dead offspring did not differ significantly among study sites and between offspring developmental stages.29.3%of unhatched eggs contained a visible embryo,and the proportion of embryo-containing unhatched eggs did not differ significantly between urban and forest study *** results suggest male-biased offspring mortality in Great Tits,and highlight the need of large datasets to detect subtle differences between habitats and developmental stages.

关键词： Great Tit Urbanization Nestling mortality sex related differences

Double-brooding and annual breeding success of great tits in urban and forest habitats

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Current Zoology 2022年第5期68卷 517-525页

作者： Boglárka Bukor Gábor seress Ivett Pipoly Krisztina sándor Csenge sinkovics ErnőVincze andrás Liker Behavioral Ecology Research Group Center for Natural SciencesUniversity of PannoniaVeszprém H-8200Hungary MTA-PE Evolutionary Ecology Research Group University of PannoniaVeszprém H-8200Hungary MTA-ELTE Comparative Ethology Research Group BudapestHungary Department of Biology Theoretical Population Ecology and Evolution GroupLund UniversityLundSweden

Urban areas differ from natural habitats in several environmental features that influence the characteristics of animals living *** example,birds often start breeding seasonally earlier and fledge fewer offspring per brood in cities than in natural ***,longer breeding seasons in cities may increase the frequency of double-brooding in urban compared with nonurban populations,thus potentially increasing urban birds’annual reproductive output and resulting in lower habitat difference in reproductive success than estimated by studies focusing on first clutches *** this study,we investigated 2 urban and 2 forests great tit Parus major populations from 2013 to *** compared the probability of double-brooding and the total number of annually fledged chicks per female between urban and forest habitats,while controlling for the effects of potentially confounding *** was a trend for a higher probability of double-brooding in urban(44%of females)than in forest populations(36%),although this was not consistent between the 2 urban *** produced significantly fewer fledglings annually in the cities than in the forest sites,and this difference was present both within single-and double-brooded ***,double-brooded urban females produced a similar number of fledglings per season as single-brooded forest *** results indicate that double-brooding increases the reproductive success of female great tits in both habitats,but urban females cannot effectively compensate in this way for their lower reproductive output per ***,other mechanisms like increased post-fledging survival can mitigate habitat differences in reproductive success.

关键词： annual reproductive success habitat differences population self-sustainability second brood urban conservation

Experimental approaches to select tree species for forest restoration:effects of light,water availability and interspecific competition in degraded areas

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Journal of Forestry Research 2022年第4期33卷 1197-1207页

作者： Johanna Croce Ernesto I.Badano Carolina B.Trigo Fernanda Martinez-Galvez andrés Tálamo Laboratorio de Ecología Aplicada a la Conservación Instituto de Bio y Geociencias del Noroeste ArgentinoConsejo de Investigaciones Científi cas y Técnicas-Universidad Nacional de SaltaAvenida Bolivia 51504400 SaltaArgentina IPICYT/División de Ciencias Ambientales Instituto Potosino de Investigación Científi ca y TecnológicaCamino a la Presa San José2055Colonia Lomas 4^(a)Sección78216 San Luis PotosíMéxico

Knowing what native trees can recr uit on degraded areas allows selecting the best species to restore these ***,as this information is not often available,experimentation is required before large-scale *** study used ex situ experiments to make these decisions on *** with r-strategist plants,excessive solar radiation and water shortage commonly impair tree recruitment in open *** experiments focused on the interactions among these factors and were conducted with three pioneer species from seasonally dry forests of northwest Argentina,Anadenanthera colubrina,Ceiba chodatii and Jacaranda *** of each species were sown at two light levels(sunlight/shade),two rainfall levels(full/reduced)and two levels of interspecific competition(with/without competitor)in a tree *** emergence and survival were monitored over a year and the results indicate that species differentially respond to varying levels of light and *** of *** tolerated water shortages under elevated solar radiation,which are desirable features for forest *** of *** tolerated shade and drought,suggesting that they require shading for establishing in open ***,*** seedlings neither tolerated full sunlight nor water shortages,suggesting that this species requires shading and regular watering if used in *** of the effects of light and water,the survival of all species was reduced by interspecific *** results highlight the importance of experimentation for selecting the best species for forest restoration and can enhance the cost/benefit ratios of these actions.

关键词： Common-garden experiments Drought Ecological restoration Interspecific competition seedling survival shade

ZigID:Improving visibility in industrial environments by combining WsN and RFID

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Journal of Zhejiang University-science A(Applied Physics & Engineering) 2011年第11期12卷 849-859页

作者： Pablo GARCíA ANsOLA andrés GARCíA Javier de las MORENAs Javier GARCíA EsCRIBANO Francisco Javier OTAMENDI Autolog Labs School of Industrial EngineeringUniversity of Castilla-La Mancha Applied Economic Department University Rey Juan Carlos

The objective of this work is to provide decision-making processes with an updated/real picture of the mobile resources in industrial environments through a constant feedback of *** combination of identification technologies and wireless sensor networks(WsN) is proposed as a key development to guarantee an accurate and timely supply of online information regarding the localization and tracking of the mobile wireless *** approach uses a cooperative and distributed localization system,called ZigID,which is a WsN based on a Zigbee network with radio frequency identification(RFID) active tags as end *** WsN can recover not only the ID information stored at the tags attached to mobile resources,but also any other useful data captured by specific sensors for acceleration,temperature,humidity and fuel *** paper also shows the development of ZigID,including devices and information flows,as well as its implementation in ground handling operations at the Ciudad Real Central Airport,spain.

关键词： Radio frequency identification(RFID) Tracking Wireless sensor networks(WsNs)

A mild, configurable, flexible CoNi-LDH（v）/Zn battery based on H-vacancy-induced reversible Zn2+ intercalation

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Journal of Energy Chemistry 2025年第1期100卷 498-508页

作者： Xinyue Cheng Dingsheng Wu Hao Gao Qingqing Wang Pengfei Lv sam s.Yoon Qufu Wei Key Laboratory of Eco-textiles Ministry of Education Jiangnan University school of Mechanical Engineering Korea University

Flexible Zn-based batteries have attracted increasing research interest as essential components of wearable energy storage ***,the advancement of flexible aqueous Zn-based batteries based on Co-Ni layered double hydroxide （CoNi-LDH） as the cathode material is hampered by their poor cycling stability and the corrosiveness of alkaline ***,CoNi-LDH nanosheets enriched with H vacancies (CoNi-LDH（v）) were constructed on a flexible carbon cloth （CC） substrate via electrochemical deposition and *** Zn-based battery comprising CoNi-LDH（v）@CC as the cathode exhibited highly reversible conversion reactions and stable operation in 3 M ZnsO4electrolyte （pH=4）.The battery delivered an excellent specific capacity (225 mA h g-1,0.26 mA h cm-2),acceptable cycling stability（53.9%,900 cycles）,and high discharging *** abundant H vacancies served as active sites for the reversible intercalation of Zn2+and the extravasation of NO3-generated channels and space for Zn2+transport and storage,together enabling an excellent Zn2+storage ***,a sandwich-structured solid-state CoNi-LDH（v）@CC//Zn@CC battery was fabricated and was found to exhibit a noteworthy electrochemical performance and mechanical *** a proof of concept,the unencapsulated battery powered a digital watch under various deformation conditions and operated stably for 80 ***,the flexible battery displayed outstanding customizability,maintaining an open-circuit voltage of 1.42 V even after being cut *** proposed engineering strategy contributes to the realization of textiles with truly wearable energy-storage devices.

关键词： CoNi/Zn battery H vacancies Mild aqueous electrolyte Tailorable battery Wearable energy storage device

species Richness, Diversity and Density of Understory Vegetation along Disturbance Gradients in the Himalayan Conifer Forest

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Journal of Mountain science 2014年第5期11卷 1182-1191页

作者： Kesang WANGCHUK andrás DARABANT Prem Bahadur RAI Maria WURZINGER Werner ZOLLITsCH Georg GRATZER University of Natural Resources and Life sciences Department of Sustainable Agricultural Systems Division of Livestock SciencesGregor Mendel Strasse 33A Vienna 1180 Austria Renewable Natural Resources Research and Development Center University of Natural Resources and Life sciences Department of Forest and Soil Sciences Institute of Forestry Ecology Peter Jordan Strasse 82A Vienna 1190 Austria

We investigated whether species richness, diversity and density of understory herbaceous plants differed along logging(gap) and grazing(primarily by cattle) disturbance gradients, and sought to identify drivers of richness, diversity and density of understory vegetation of logged sites. A factorial experiment was conducted in the mixed conifer forest of Gidakom in Western Bhutan. Levels of the logging treatment included small(0.15 – 0.24 ha), medium(0.25 – 0.35 ha) and large(0.36 – 1.31 ha) gaps. The grazing treatment included grazed(primarily by cattle) and ungrazed(where herbivores were excluded by a fence) plots nested within each gap. Data were collected from 12 gaps(4 replicates at each level of logging) using the point intercept method. shannon Weaver Diversity and Margalef's indices were used to estimate species diversity and describe species richness, respectively. soil samples were analyzed for pH and nutrients. The interaction effect of logging and grazing was significant(p≤0.001) only on species diversity. Relative to ungrazed areas, species diversity was significantly higher(0.01≤p≤0.05) in medium grazed gaps. Under grazed conditions, soil P was negatively correlated with gap size and species diversity. While species diversity was positivelycorrelated(0.01≤p≤0.05) with soil N in grazed plots species richness was positively correlated(0.001≤p≤0.01) with soil N in ungrazed plots. Relative density of Yushania microphylla and Carex nubigena were higher under ungrazed conditions. Our study suggests that the combined effect of cattle grazing and logging results in higher species diversity of understory vegetation in medium and grazed gaps in mixed conifer forests of Bhutan,whereas increase or decrease in relative density of major species is determined primarily by the independent effects of grazing and logging. From management perspective, forest managers must refrain from creating large gaps to avoid loss of nutrients(mainly P and N), which may eventually aff

关键词： Forest gap Grazing Relative density soil nutrients species diversity species richness