检索结果-南通市图书馆

Drying Drop Technology as a possible Tool for Detection Leukemia and Tuberculosis in Cattle

Journal of Biomedical Science and Engineering 2015年第1期8卷 1-23页

作者： Tatiana A. Yakhno anatoly A. Sanin Robert G. Ilyazov Gulusa V. Vildanova Rafat A. Khamzin Nadezhda p. Astascheva Mikhail G. Markovsky Vadim D. Bashirov Vladimir G. Yakhno Department of Radiophysical Methods in Medicine Institute of Applied Physics Russian Academy of Sciences (IAP RAS) Nizhny Novgorod Russia Department of Agricultural Sciences Academy of Sciences of the Republic of Tatarstan (AS RT) Kazan Russia Department of Biotechnology and Standardization Bauman Kazan State Academy of Veterinary Medicine (KSAVM) Kazan Russia Department of Technique and Technology Financial Technological Academy (FTA) Moscow Region Korolyev Russia Department of Trial Wine-Making North-Caucasian Zonal Research Institute of Horticulture and Viticulture of the Russian Academy of Agricultural Sciences (NCZRIH & V) Krasnodar Russia Department of Food Biotechnology Orenburg State University (OSU) Orenburg Russia

Usual response of organism to viral or bacterial invasion represents antibodies production, qualitative and quantitative changes in composition of biological fluids. These changes influence conformation and surface characteristics of macromolecules (proteins), which become apparent in sessile drying drops, when they form aggregates due to salting-out effect and sediment. The bottom adsorption layers change their adhesive and viscoelastic properties in time depending on fluid composition and structure. The aim of this study was verification the idea of using this phenomenon in rapid vet diagnostics. Milk, blood and serum samples of 183 cows were tested using Drop Drying Technology (DDT). A drop of tested fluid dried on a polished quartz plate, oscillated with constant frequency—60 kHz. Mechanical properties of the drop changed during drying, influenced the electrical conductivity of the quartz plate. This signal was converted to the Acoustical- Mechanical Impedance (AMI) and displayed as a curve in coordinates AMI vs. Time. Shape of the AMI curve reflected this dynamics, and was used as a target for quantitative comparison between control and infected animals. Frequency analysis of the estimated parameters of the curves was performed using features of the Excel program. powerful method of artificial neural network processing of the experimental data was also tested in this work as a possible tool for future development. Significant differences between control, Bovine leucosis virus positive (BLV+) and Bovine tuberculin positive (BTub+) cattle groups were obtained using all biological fluids—blood, serum and milk. We fixed also a season shift of the data, but distinction between groups still remained. In serum and milk some features of the AMI curves were more stable, and retained diagnostic properties when combined winter and spring databases. Further development of DDT is proposed.

关键词： Sessile Drying Drops Biological Fluids Dynamics of Mechanical properties Acoustical Impedancemetry Vet Diagnostics

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

镉对生命活动的毒作用机制

引用

环境与职业医学 2018年第5期35卷 460-470页

作者： Alexey A.TINKOV Olga p.AJSUVAKOVA Jan AASETH Yordanka G.GLUHCHEVA Juliana M.IVANOVA Geir BJФRKLUND Margarita G.SKALNAYA Oksana A.SKALNAYA 黄百粲林雪 anatoly V.SKALNY 国立雅罗斯拉夫大学俄罗斯雅罗斯拉夫150003 俄罗斯科学院细胞与细包共生研究所俄罗斯奥伦堡460001 RUDN大学俄罗斯莫斯科117198 国立奥伦堡教育大学俄罗斯奥伦堡460000 黑得马克应用科学大学挪威艾佛伦2411 英兰德信托医院研究部挪威布鲁门达2380 保加利亚科学院实验形态学、病理学与人类学学院暨博物馆保加利亚索非亚1113 索非亚大学医学系保加利亚索非亚1113 营养与环境医学咨议会挪威莫伊拉娜8602 台湾大学中国台湾10617 台北医学大学万芳医院职业医学科中国台湾10675 湖南农业大学动物科学技术学院湖南长沙410128 联合国教科文组织微量元素研究所法国里昂69000 国立奥伦堡大学俄罗斯奥伦堡460000

镉是一种众所周知的环境毒物,对人体健康有重大危害。镉与众多疾病相关,例如癌症、神经退化性疾病和代谢综合征等。虽然疾病种类各异,但是都与镉的化学性质和毒作用机制有关。镉易与含硫氮功能基结合,从而取代金属酶内的必需元素锌。镉... 详细信息

镉是一种众所周知的环境毒物,对人体健康有重大危害。镉与众多疾病相关,例如癌症、神经退化性疾病和代谢综合征等。虽然疾病种类各异,但是都与镉的化学性质和毒作用机制有关。镉易与含硫氮功能基结合,从而取代金属酶内的必需元素锌。镉的促炎症效应伴随促炎因子[肿瘤坏死因子(TNF-α)、白介素(IL)-1、IL-6]的大量产生和抗炎因子(IL-1拮抗剂、IL-4、IL-6、IL-10、IL-13)的明显减少,并且镉的促炎症活性与其通过各种途径所诱导的氧化应激紧密相关。镉还能取代各种蛋白质内的铁铜原子,从而增加自由氧化还原反应的活性金属库,激活芬顿(Fenton)反应;反之,镉对电子传递链的抑制损害了对氧气的利用,增加了活性氧的产生。最后,镉对抗氧化酶的抑制加剧自由基对核酸等生物大分子的损伤,引起遗传毒性并改变基因调控。因此,干扰镉的毒作用机制是预防镉暴露不良健康效应的有效措施。

关键词：镉氧化应激毒性炎症遗传毒性

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

polariton lasing in Mie-resonant perovskite nanocavity

引用

Opto-Electronic Advances 2024年第4期7卷 27-42页

作者： Mikhail A.Masharin Daria Khmelevskaia Valeriy I.Kondratiev Daria I.Markina Anton D.Utyushev Dmitriy M.Dolgintsev Alexey D.Dmitriev Vanik A.Shahnazaryan anatoly p.pushkarev Furkan Isik Ivan V.Iorsh Ivan A.Shelykh Hilmi V.Demir Anton K.Samusev Sergey V.Makarov UNAM-Institute of Materials Science and Nanotechnology National Nanotechnology Research CenterDepartment of Electrical and Electronics EngineeringDepartment of PhysicsBilkent UniversityAnkara 06800Turkey ITMO University School of Physics and EngineeringSt.Petersburg 197101Russia Abrikosov Center for Theoretical physics MIPTDolgoprudnyiMoscow Region 141701Russia LUMINOUS!Center of Excellence for Semiconductor Lighting and Displays School of Electrical and Electronic EngineeringSchool of Physical and Mathematical SciencesSchool of Materials Science and EngineeringNanyang Technological UniversitySingapore 639798Singapore Department of physics Engineering Physics and AstronomyQueen’s UniversityKingstonOntario K7L 3N6Canada Science Institute University of IcelandDunhagi 3IS-107ReykjavikIceland Experimentelle physik 2 Technische Universität DortmundDortmund 44227Germany Qingdao Innovation and Development Center Harbin Engineering UniversityQingdao 266000China

Deeply subwavelength lasers(or nanolasers)are highly demanded for compact on-chip bioimaging and sensing at the *** of the main obstacles for the development of single-particle nanolasers with all three dimensions shorter than the emitting wavelength in the visible range is the high lasing thresholds and the resulting *** we ex-ploit exciton-polariton condensation and mirror-image Mie modes in a cuboid CspbBr3 nanoparticle to achieve coherent emission at the visible wavelength of around 0.53μm from its ultra-small(≈0.007μm3 or≈λ3/20)semiconductor *** polaritonic nature of the emission from the nanocavity localized in all three dimensions is proven by direct com-parison with corresponding one-dimensional and two-dimensional waveguiding systems with similar material *** a deeply subwavelength nanolaser is enabled not only by the high values for exciton binding energy(≈35 meV),re-fractive index(>2.5 at low temperature),and luminescence quantum yield of CspbBr3,but also by the optimization of po-laritons condensation on the Mie resonances with quality factors improved by the metallic ***,the key parameters for optimal lasing conditions are intermode free spectral range and phonons spectrum in CspbBr3,which govern polaritons condensation *** chemically synthesized colloidal CspbBr3 nanolasers can be potentially de-posited on arbitrary surfaces,which makes them a versatile tool for integration with various on-chip systems.

关键词： nanolaser perovskite polariton Mie resonance exciton-polariton

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

辽诱系列玉米单倍体诱导系的选育

引用

玉米科学 2020年第1期28卷 25-30页

作者：刘欣芳马骏齐欣弓雪孟庆国 Eduard Khatefov Suprunov anatoly 赵念力白添姜敏王延波辽宁省农业科学院玉米研究所沈阳110161 俄联邦研究中心瓦维洛夫全俄植物遗传资源研究所俄罗斯俄联邦国家预算科学机构p.p.国家谷类研究中心俄罗斯东北育才学校沈阳110179

采用多个测验种逐代跟踪测定诱导率的方法,利用俄罗斯引进的单倍体诱导系资源,经过5年7代选育出辽诱系列玉米单倍体诱导系辽诱1号、辽诱2号、辽诱3号和辽诱4号。对22个品种的诱导效果试验表明,辽诱1号、辽诱2号、辽诱3号和辽诱4号的综... 详细信息

采用多个测验种逐代跟踪测定诱导率的方法,利用俄罗斯引进的单倍体诱导系资源,经过5年7代选育出辽诱系列玉米单倍体诱导系辽诱1号、辽诱2号、辽诱3号和辽诱4号。对22个品种的诱导效果试验表明,辽诱1号、辽诱2号、辽诱3号和辽诱4号的综合诱导率分别为6.85%、7.53%、6.66%和6.03%,比对照高诱五号分别高出0.6倍、0.8倍、0.6倍和0.4倍。诱导基因检测结果表明,辽诱系列诱导系具有诱导率高、花粉量大、抗病、抗倒、易繁殖等优良特性,且存在和高诱五号共同的诱导基因GRMZM2G471240,是开展玉米单倍体育种的理想诱导系。

关键词：玉米单倍体诱导系平均诱导率综合诱导率诱导基因

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Large-scale genome-wide SNp analysis reveals the rugged(and ragged)landscape of global ancestry,phylogeny,and demographic history in chicken breeds

引用

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2024年第4期25卷 324-340页

作者： Natalia V.DEMENTIEVA Yuri S.SHCHERBAKOV Olga I.STANISHEVSKAYA anatoly B.VAKHRAMEEV Tatiana A.LARKINA Artem p.DYSIN Olga A.NIKOLAEVA Anna E.RYABOVA Anastasiia I.AZOVTSEVA Olga V.MITROFANOVA Grigoriy K.pEGLIVANYAN Natalia R.REINBACH Darren K.GRIFFIN Michael N.ROMANOV Russian Research Institute of Farm Animal Genetics and Breeding-Branch of the L.K.Ernst Federal Research Centre for Animal Husbandry.pushkin St.Petersburg196601Russia School of Biosciences University of KentCanterburyCT27NJUK L.K.Ernst Federal Research Center for Animal Husbandry DubrovitsyPodolskMoscow Oblast142132Russia

The worldwide chicken gene pool encompasses a remarkable,but shrinking,number of divergently selected breeds of diverse *** study was a large-scale genome-wide analysis of the landscape of the complex molecular architecture,genetic variability,and detailed structure among 49 *** populations represent a significant sample of the world's chicken breeds from Europe(Russia,Czech Republic,France,Spain,UK,etc.),Asia(China),North America(USA),and Oceania(Australia).Based on the results of breed genotyping using the Illumina 60K single nucleotide polymorphism(SNp)chip,a bioinformatic analysis was carried *** included the calculation of heterozygosity/homozygosity statistics,inbreeding coefficients,and effective population *** also included assessment of linkage disequilibrium and construction of phylogenetic *** multidimensional scaling,principal component analysis,and ADMIXTURE-assisted global ancestry analysis,we explored the genetic structure of populations and subpopulations in each *** overall 49-population phylogeny analysis was also performed,and a refined evolutionary model of chicken breed formation was proposed,which included egg,meat,dual-purpose types,and ambiguous *** a large-scale survey of genetic resources in poultry farming using modern genomic methods is of great interest both from the viewpoint of a general understanding of the genetics of the domestic chicken and for the further development of genomic technologies and approaches in poultry *** general,whole genome SNp genotyping of promising chicken breeds from the worldwide gene pool will promote the further development of modern genomic science as applied to poultry.

关键词： Chicken genome diversity Single nucleotide polymorphism(SNp)analysis Gene pool Global ancestry phylogeny Demographic history

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A Study of Calcifying Nanoparticles Extracted from the Vorotilovskaya Well

引用

材料科学与工程（中英文B版） 2012年第8期2卷 464-470页

作者： Sergey V. Vasile anatoly B. Churilo Olga Y. prikhodko Alexander S. Rudy Nina V. Shekhovtsova Anastasiya Y. Yagushkina Facilities Sharing Centre "Micro-and Nanostructures Diagnosis" Yaroslavl State University 14 Sovetskaya street Yaroslavl150000 Russia Yaroslavl Branch of physics and Technology Institute of Russian Academy of Sciences 21 Universitetskaya street Yaroslavl150007 Russia Department of Biology Yaroslavl State University 14 Sovetskaya street Yaroslavl 150000 Russia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：