检索结果-南通市图书馆

Forecasti.g of Survi.al Rate i. Pati.nts wi.h the Early Stage of Non Small Cell Lung Cancer

Journal of Cancer Therapy 2013年第10期4卷 1472-1477页

作者： Oleksey P. Kolesni. anatoliy i. shevchenko Yuri. E. Lyakh Vi.ali. G. Guri.nov Department of Medi.al Bi.physi.s Medical Informatics and Biostatistics M. Gorky Donetsk National Medical University Donetsk Ukraine Department of Oncology Zaporizhzhya State Medical University Zaporizhzhya Ukraine

Lung cancer i. the most common cause of death from oncologi.al di.eases all over the world. Pri.ary treatment of pati.nts wi.h the early stage of non-small cell lung cancer i. a surgery. However, after surgery 30% - 85% of pati.nts undergo di.ease progressi.n. i. order to i.prove the results of treatment of pati.nts wi.h non-small cell lung cancer i. i. necessary to separate a group of pati.nts wi.h di.mal prognosi. for whom adjuvant chemotherapy wi.l permi. i.provi.g the survi.al rate. The ai. of our research was to create a forecasti.g model wi.h a vi.w to detect the pati.nts wi.h the early stage of non-small cell lung cancer and di.mal prognosi.. Our research covered 254 pati.nts wi.h the early stage of non-small cell lung cancer who underwent a cure from June 2008 ti.l December 2012 i. the department of thoraci. surgery of Zapori.hzhi. Regi.nal Cli.i.al Oncologi. Di.pensary. i. order to i.enti.y the factors connected wi.h the ri.ks of low survi.al rate of pati.nts wi.h the early stage of non-small cell lung cancer after curati.e treatment (surgi.al treatment, adjuvant chemotherapy), a method of desi.n of neural network models of classi.i.ati.n was used. 39 factors were taken for i.put characteri.ti.s. Duri.g i.vesti.ati.n two forecasti.g models were bui.t. As follows from the analysi. of fi.st forecasti.g model wi.h the i.crease of the pati.nt’s BMi. the ri.k of low pati.nt survi.al rate stati.ti.ally and si.ni.i.antly (p = 0.03) decreases, OR = 0.89 (95% Ci.0.80 - 0.99) for each kg/m2 i.dex value. The ri.k of low pati.nt survi.al rate also decreases (p = 0.02) i. he has a squamous cell carci.oma, OR = 0.36 (95% Ci.0.15 - 0.88) compared wi.h other hi.tologi.al forms of tumor. The connecti.n between the ri.k of low pati.nt survi.al rate and the volume of surgi.al i.terventi.n was di.covered (p = 0.01), OR = 3.19 (95% Ci.1.29 - 7.86) for pati.nts who underwent a pulmonectomy compared wi.h pati.nts who underwent an upper bi.obectomy. As follows from the analysi. of

关键词： Forecasti.g Model Survi.al Rate Non-Small Cell Lung Cancer

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Usage of Cox-Regressi.n Model for Forecasti.g of Survi.al Rate i. Pati.nts wi.h the Early Stage of Non-Small Cell Lung Cancer

引用

Advances i. Lung Cancer 2014年第1期3卷 26-33页

作者： Oleksey P. Kolesni. anatoliy i. shevchenko Yuri. E. Lyakh Vi.ali. G. Guri.nov Pavel A. Alyoshechki. Department of Medi.al Bi.physi.s Medical Informatics and Biostatistics M. Gorky Donetsk National Medical University Donetsk Ukraine Department of Oncology Zaporizhzhya State Medical University Zaporizhzhya Ukraine

i. the past decades a lot of i.vesti.ati.ns were focused on searchi.g for more accurate markers of lung cancer progressi.n. Researchers i.di.ate that molecular markers may be useful i. forecasti.g of treatment outcome and overall survi.al rate i. pati.nts wi.h non-small cell lung cancer. The ai. of our research was to create a forecasti.g model i. order to i.enti.y pati.nts wi.h stage i.i. of non-small cell lung cancer and di.mal prognosi.. Our research covered 254 pati.nts wi.h the early stage of non-small cell lung cancer who underwent a cure from June 2008 ti.l December2012 i.the Department of Thoraci. Surgery of Zapori.hzhi. Regi.nal Cli.i.al Oncologi. Di.pensary. Surgery was performed for all pati.nts. Adjuvant chemotherapy was performed for 101 pati.nts. i. order to carry out multi.ari.te Cox-regressi.n analysi., STATi.Ti.A 6.0 (StatSoft i.c.) program was used. The most si.ni.i.ant from 39 vari.bles were selected (tumor si.e, hi.tologi.al form of tumor, volume of surgi.al i.terventi.n, volume of conducted lymph node di.secti.n, Ki.67 expressi.n, EGFR expressi.n, E-cadheri. expressi.n). We propose the computer system whi.h can forecast survi.al rate i. pati.nts wi.h the early stage of non-small cell lung cancer.

关键词： Forecasti.g Model Survi.al Rate Non-Small Cell Lung Cancer

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Detecti.n and evaluati.n of di.ferent morphologi.al forms of Mycoplasma homi.i. i. human semen

引用

Asi.n Journal of Andrology 2024年第1期26卷 71-76页

作者： Eli.aveta Bragi.a Tatyana Soroki.a Avtandi. Chogovadze Yuli. shevchenko Vyacheslav Chernykh Olga Barkhatova i.i.a Rakovskaya Research Centre for Medi.al Geneti.s Moscow 115522Russia A.N.Belozersky i.sti.ute of Physi.o-Chemi.al Bi.logy Lomonosov Moscow State Uni.ersi.y Moscow 119992Russia Reprolab Li.i.ed Li.bi.i.y Company Moscow 119333Russia N.i.Pi.ogov Russi.n Nati.nal Research Medi.al Uni.ersi.y Moscow 117997Russia Federal Government Budgetary i.sti.uti.n"Nati.nal Research Center for Epi.emi.logy and Mi.robi.logy Named after Honorary Academi.i.n N.F.Gamaleya of the Mi.i.try of Health of the Russi.n Federati.n" Moscow 123098Russia

Recently di.covered mi.rocoloni.l forms of Mycoplasma homi.i.(***)and thei. i.pact on human spermatogenesi. are *** spermatozoa of 125 ferti.e men(sperm donors;from Reprobank[Reproducti.e Ti.sue Bank,Moscow,Russi.l)and of 93 pati.nts wi.h ferti.i.y problems(from the Federal State Budgetary i.sti.uti.n"Research Centre for Medi.al Geneti.s[RCMG]",Moscow,Russi.)were *** coloni.s of *** and mi.rocoloni.s were detected by molecular bi.logi.al methods,culture of bacteri.,and transmi.si.n electron *** uni.ue structure of mi.rocoloni.l cells,i. whi.h the cytoplasmi. cyli.der i. surrounded by concentri. electron-dense and electron-li.ht layers wi.h a peri.di.i.y of 12-14 nm,and the abi.i.y of mi.rocoloni.l cells to attach to spermatozoa are *** pati.nts wi.h lower sperm quali.y,mi.rocoloni.s of *** were detected 2.5 ti.es more frequently than classi.al *** detecti.n of mi.rocoloni.s i. the ejaculate and the frequent i.olati.n of mi.rocoloni.s from sperm samples of pati.nts wi.h ferti.i.y problems suggest that mi.rocoloni.l cells may be one cause of i.ferti.i.y.

关键词： ejaculate ferti.i.y Mycoplasma homi.i. spermatogenesi. transmi.si.n electron mi.roscopy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Structural Changes and Electrodynami. Effects i. Polymers under Fast Uni.xi.l Compressi.n

引用

Chi.ese Journal of Polymer Sci.nce 2021年第5期39卷 601-609,I0007页

作者： Aleksey.i.Aleksandrov i.an A.Aleksandrov Vi.ali. G.shevchenko Aleksandr N.Ozeri. N.S.Eni.olopov i.sti.ute of Syntheti. Polymeri. Materi.ls RAS 117393 Moscow Profsoyuznaya70 Russian Federation

Rheologi.al explosi.n i. polymers under uni.xi.l compressi.n i. an open volume occurs at the end of conti.uous rapi. plasti. deformati.n after several stages of *** types of polymers were chosen for thi. study:bri.tle glassy amorphous polystyrene and thermoplasti. semi.crystalli.e *** pulses were detected duri.g explosi.n,and thei. spectra were analyzed wi.h two models.X-ray di.fracti.n methods were used to i.vesti.ate changes i. the structure and morphology of polymers duri.g deformati.n and rheologi.al *** pores appear i. polymer i. thi. process,and thei. shape and si.e di.tri.uti.n were deri.ed from X-ray *** mai. reason for the formati.n of pores i. polymer samples i. rheologi.al explosi.n experi.ents i. the i.tense mi.roshi.ts i. the polymer volume under the acti.n of hi.h appli.d pressure.

关键词： Polystyrene Polypropylene X-ray Mechani.al properti.s Compressi.n

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Relati.nshi. between Marx and Marxi.m: the Relevance of the i.sue: i. the XXi.t Century

引用

学术界 2019年第1期 190-196页

作者： Vladi.i. shevchenko i.sti.ute of Phi.osophy Russi.n Acadamy of Sci.nce

The paper looks at the i.sue of the relati.nshi. between Marx and Marxi.m. Three approaches to the i.sue,whi.h are wi.espread i. contemporary Marxi.t li.erature and among marxologi.ts are di.cussed. The fi.st approach: the true Marx i. the phi.osophy of Marx mi.us poli.i.al theory. The second approach: the true Marx i. the phi.osophy of Marx plus poli.i.al theory of soci.l-democrati. parti.s. The thi.d approach: the true Marx i. the phi.osophy of Marx plus poli.i.al theory,developed most fully by Leni. i. the preparati.n of the R ussi.n revoluti.n. The thi.d approach,from our poi.t of vi.w,corresponds most to the essence of genui.e Marxi.m,at least as appli.d to the twenti.th century. The paper exami.es i. detai. the pri.ci.al novelty of Leni. speaki.g of the need to translate Marx's materi.li.ti. theory of hi.tory to the poli.i.al level as a theoreti.al i.sue. The author also notes the contri.uti.n of the Chi.ese leaders i.to further development of the poli.i.al theory of Marxi.m closely connected wi.h the i.sues of strategy and tacti.s of bui.di.g soci.li.m wi.h Chi.ese characteri.ti.s. i. conclusi.n,the paper states that world hi.tory nowbecomes i.creasi.gly complex and mi.ed. Therefore,the questi.n of whether Marxi.t phi.osophers i. thi. si.uati.n wi.l be able to fi.d ways of reali.ati.n the 11th thesi. of Marx "On Feuerbach"remai.s open.

关键词： Marx true Marxi.m three approaches Leni. Chi.ese development

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Evaluati.n of ai.li.t pump performance for verti.al conveyi.g of coal parti.les

引用

i.ternati.nal Journal of Coal Sci.nce & Technology 2023年第3期10卷 155-166页

作者： Parvi. Enany Oleksandr shevchenko Carsten Drebenshtedt Faculty of Mi.i.g and Speci.l Ci.i. Engi.eeri.g Technische Universitat BergakademieGustav-Zeuner StraBe 1A09599 FreibergGermany UTF GmbH ErzstraBe 1509618 Brand-ErbisdorfGermany

One of the cruci.l aspects of reduci.g ai. consumpti.n when conveyi.g parti.les wi.h an ai.li.t pump i. to know the factors that affect the process of parti.le moti.n at an i.i.i.l veloci.y of *** determi.e the i.fluence of submer-gence rati. and physi.al properti.s of parti.les(such as si.e,shape,and mass)on the onset of verti.al parti.le moti.n,the ai.li.t pump was taken as the research object,and spheri.al glass together wi.h i.regular shaped coal were used as experi.ental test *** results show that unli.e the water-soli. envi.onment,the start of parti.le moti.n i. the water-ai. mi.ture does not always occur at a certai. value of superfi.i.l water veloci.y and thi. value also i.creases wi.h i.creasi.g submergence *** the parameters consi.ered,the role of submergence rati. i. much more effecti.e than the di.ensi.ns and the shape of the parti.le,because by i.creasi.g submergence from 0.3 to 0.8,i. i. possi.le to reduce ai. consumpti.n by up to 8 *** on thi. study the correspondi.g theoreti.al model deri.ed by Fuji.oto et *** opti.i.ed,wherei. the overall agreement between the modi.i.d theory and present experi.ental data i. parti.ularly *** to Fuji.oto,the mi.i.um superfi.i.l water veloci.y for li.ti.g soli.s i. the ai.-water mi.ture i. not always smaller than water ambi.nt whi.h i.di.ates on opti.um submergence rati. hi.her than ***,a new cri.eri.n was i.troduced to descri.e the moment of onset of the parti.le moti.n as a functi.n of the superfi.i.l flui. veloci.y rati. for each submergence value.

关键词： Ai.-water-soli. flow Slurry- Coal Submergence rati. Taylor bubble Superfi.i.l veloci.y

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Comparati.e Case Study on Hosti.e Takeovers i. Chi.a and Russi.

Comparative Case Study on Hostile Takeovers in China and Rus...

引用

作者： shevchenko Kri.ti.a 华东师范大学

学位级别：硕士

本文对中国和俄罗斯的恶意并购活动进行了不同的观察。我依据制度背景,简要的立法描述和中西经验以及西方并购模式的比较来构建我的论文。我对两个国家最近发生的两起恶意并购企图进行了案例研究,并在最后一章中对恶意并购模式进行了比... 详细信息

本文对中国和俄罗斯的恶意并购活动进行了不同的观察。我依据制度背景,简要的立法描述和中西经验以及西方并购模式的比较来构建我的论文。我对两个国家最近发生的两起恶意并购企图进行了案例研究,并在最后一章中对恶意并购模式进行了比较。得出的结论是,两国并购模式的主要差异可以分为经济和法律两个方面。根据进行的比较,两国恶意并购的企业氛围正在发生变化。国家参与控制恶意并购的过程在中国模式中比俄罗斯更加明确。关于投资者的吸引力,企业家的资本和商业环境安全水平,中国模式更为有利。由于研究局限性导致数据不可用,并且关于该主题的学术研究的数量微不足道,为了更好地理解问题,必须进行进一步的研究并不断监测立法的变化。

关键词：兼并和收购恶意并购中国俄罗斯对照

来源：

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

Pre-cli.i.al evaluati.n of soybean-based wound dressi.gs and dermal substi.ute formulati.ns i. pi. heali.g and non-heali.g i. vi.o models

引用

Burns & Trauma 2014年第4期2卷 187-195页

作者： Rosti.lav V.shevchenko Matteo Santi. Pharmi.ex Pharmaceuti.al Servi.es Ltd London Bri.hton Centre for Regenerati.e Medi.i.e University of BrightonBrightonUnited Kingdom

i. the last decade,a new class of natural bi.materi.ls deri.ed from de-fatted soybean fl our processed by ei.her thermoset or extracti.n procedures has been *** bi.materi.ls uni.uely combi.e adaptabi.i.y to vari.us cli.i.al appli.ati.ns to proven ti.sue regenerati.n *** the present work,the bi.materi.ls were formulated ei.her as hydrogel or as paste formulati.n and thei. potenti.l as wound dressi.g materi.l or as dermal substi.ute was assessed by two i. vi.o models i. pi. ski.:The heali.g full-thi.kness punch bi.psy model and the non-heali.g full-thi.kness polytetrafl uoroethylene(PTFE)chamber *** results clearly show that collagen deposi.i.n i. i.duced by the presence of these bi.materi.ls.A uni.ue pattern of early i.fl ammatory response,eli.i.i.g neutrophi.s and controlli.g macrophage i.fi.ltrati.n,i. followed by ti.sue cell coloni.ati.n of the wound bed wi.h a si.ni.i.cant deposi.i.n of collagen fi.*** study also hi.hli.hted the i.portance i. the use of opti.al formulati.ns and appropri.te handli.g upon *** large si.e,non-heali.g wounds,wound dermi. was best obtai.ed wi.h the paste formulati.n as hydrogels appeared to be too loose to ensure lasti.g scaff oldi.g *** the contrary,packi.g of the granules duri.g the appli.ati.n of paste reduced bi.materi.l degradati.n rate and prevent the penetrati.n of newly vasculari.ed ti.sue,thus i.pedi.g grafti.g of spli.-thi.kness autologous ski. grafts on the dermal substi.ute base.

关键词： Dermal substi.utes i. vi.o models wound dressi.gs soyabean-based bi.materi.ls

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Trai.i.g of Future Teachers i. Ukrai.e and Chi.a

引用

Fronti.rs of Educati.n i. Chi.a 2018年第2期13卷 288-314页

作者： Li.bov HUNKO Natali.a PAZi.RA Kateri.a shevchenko i.sti.ute of Educati.n Studi.s and Adult Educati.n National Academy of Pedagogical Sciences of UkraineKyiv 02000Ukraine Department of Avi.ti.n Engli.h National Aviation University03058 KyivUkraine

Thi. paper explores di.ti.cti.e features of Bachelor of Educati.n(***.)trai.i.g at several well known Ukrai.i.n and Chi.ese *** analysi. was performed taki.g i.to consi.erati.n i.portant cri.eri. i. the educati.nal process of the degree programs(legi.lati.e,soci.l,organi.ati.nal,technologi.al).The Chi.ese experi.nce i. of parti.ular i.terest to Ukrai.i.n educators because of Chi.a’s anci.nt hi.tory and educati.nal *** changes took place i. the educati.n systems of both countri.s i. the peri.d of transi.i.n to a market-based economy i. the 1990s and to knowledge-based *** contri.uti.n of the educati.nal system to fast economi. development of Chi.a has brought the county to second place among the largest economi.s i. the *** authors found si.i.ari.i.s i. the documentati.n on the organi.ati.n of educati.nal processes at the uni.ersi.i.s,the shared purpose of the trai.i.g,the use of tradi.i.nal forms of educati.n,and the emphasi. on the practi.al part of the *** the same ti.e,di.ferent features were found i. the content of theoreti.al trai.i.g,the organi.ati.n of practi.al trai.i.g,the approaches to i.novati.n,the soci.l benefi.s provi.ed to teachers,the presti.e of the teachi.g professi.n,pri.ci.les of moral educati.n,as well as fi.anci.l and techni.al *** authors consi.ered a number of progressi.e i.eas i. Chi.a’s ***,the i.plementati.n of whi.h,at nati.nal and i.sti.uti.nal levels i. Ukrai.e,mi.ht contri.ute consi.erably to the moderni.ati.n of pedagogi.al educati.n.

关键词： Bachelor of Educati.n(B.Ed.) uni.ersi.y teacher pedagogi.al educati.n comparati.e analysi.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

TNF-α gene polymorphi.ms: associ.ti.n wi.h age-related macular degenerati.n i. Russi.n populati.n

引用

i.ternati.nal Journal of Ophthalmology(Engli.h edi.i.n) 2019年第1期12卷 25-29页

作者： Valeri. Chernykh Alla shevchenko Vladi.i. Konenkov Vi.tor Prokofi.v Alena Eremi.a Alexander Trunov Novosi.i.sk Branch S.Fyodorov Eye microsurgery Federal State Sci.nti.i. i.sti.ute of Cli.i.al and Experi.ental Lymрhology

Ai.: To study polymorphi.ms i. promotor regi.ns of tumor necrosi. factor(TNF)-α TNF-863 A/C(rs1800630), TNF-308 A/G(rs1800629), and TNF-238 A/G(rs361525) i. pati.nts wi.h age-related macular degenerati.n(AMD) and associ.ti.ns of complex TNF-α genotypes wi.h AMD. METHODS: One hundred and two pati.nts(82 women, 20 men; mean age 64.2±1.2 y) wi.h AMD and 100 healthy age-and sex-matched controls(82 women, 18 men; 60±1.4 y) were i.cluded i. the study. All subjects were Caucasi.n, all subjects and thei. parents were i.habi.ants of Russi.. Genomi. DNA was obtai.ed from EDTA-preserved blood usi.g the standard phenol-chloroform method. Polymorphi.ms were detected by polymerase chai. reacti.n followed by the restri.ti.n fragment length polymorphi.m method. The followi.g TNF-α genotypes were studi.d: TNF-α-238 AA, GA, GG, TNF-α-308 AA, GA, GG, TNF-α-863 AA, CA, CC. RESULTS: Di.ferences i. TNF-α-863 and TNF-α-238 genotypes frequenci.s i. pati.nts wi.h AMD and healthy controls were not found. The di.tri.uti.n of TNF-α-308 AA and TNF-α-308 GA genotypes was si.ni.i.antly di.ferent between the studi.d group and the controls [odds rati.s(OR) =0.22, P=0.0287 and OR=2.91, P=0.0063, respecti.ely]. TNF-863 CC/TNF-308 GA and TNF-308 GA/TNF-238 GG genotypes were associ.ted wi.h the i.creased ri.k of AMD(OR=2.48, P=0.0332 and OR=2.51, P=0.0187, respecti.ely). Fi.e genotypes combi.ati.ns appeared to be protecti.e. CONCLUSi.N: i. the present study, si.gle nucleoti.e polymorphi.ms and complex polymorphi.ms of one of the key i.flammatory cytoki.es TNF-α, and a number of si.ni.i.ant associ.ti.ns of these polymorphi.ms wi.h AMD i. Russi.n populati.n have been shown. Complexanalysi. of genotypes could be i.portant i. AMD ri.k factors detecti.n and studyi.g pathogenesi..

关键词： tumor necrosi. factor-a geneti. polymorphi.ms age-related macular degenerati.n

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：