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study of corneal biomechanical properties in patients with childhood glaucoma

International Journal of Ophthalmology(English edition) 2020年第12期13卷 1922-1927页

作者： sara Garcia Caride Lucia Perucho González Federico sáenz Francés Julián García Feijoo Ophthalmology Clinico San Carlos HospitalProfesor Martín Lagos StreetMadridES 28040Spain

AIM:To study of corneal biomechanical properties and intraocular pressure(IOP)measured with Corvis scheimpflug Technology(sT)in patients with childhood glaucoma(CG).METHODs:Cross-sectional study in which 89 eyes were included 56 of them with *** one eye per patient was *** following variables were obtained from the clinical history and the ophthalmological examination:age,sex,IOP,number of surgeries,and the cup/disc ratio(CDR).The following parameters were recorded using Corvis sT:corrected by biomechanics IOP(b IOP),not corrected IOP(nct IOP),central corneal thickness(CCT),maximum concavity[radius,peak distance(PD)and deformation amplitude],applanation 1 and 2(length and velocity).The mean age was 23±14.55 and 33±19.5 years old for the control group and CG group,*** 36 were males and 53 were *** the CG group,7 patients were controlled only with medical *** had at least one previous goniotomy,19 had at least one trabeculectomy,and 11 had an Ahmed ***:A significant and positive intraclass correlation coefficient was found between Goldman IOP and the IOP measured by Corvis in both *** differences were found between the IOP measured with Corvis and Goldman using a student *** biomechanical parameters,there were differences in the applanation length 2(A-L2),in the applanation velocity 2(A-V2)and in the *** sex,only the applanation length 1(A-L1)was found to be different in control group.A positive and significant Pearson correlation was found between CDR and the ***:Corneal biomechanical properties have shown differences between CG and healthy subjects and also between men and women.

关键词： childhood glaucoma biomechanical properties Corvis scheimpflug Technology

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An Intelligent Agent Approach to Adaptive Project Management

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Tsinghua science and Technology 2008年第S1期13卷 121-125页

作者： I. Ourdev s. AbouRizk Hole school of Construction Department of Civil and Environmental Engineering

This paper presents the initial steps to integrating a distributed discrete event simulation system with a framework for intelligent software agents. The resulting system has a simulation component that is based on the high-level architecture (HLA) and an agent component that implements the belief-desire-intention (BDI) approach to agent modelling. The architecture is connected to a real-time information source. The framework was successfully applied to a real-life monitoring system for a tunnel-boring machine excavation project that helped with forecasting and managing the project timelines in response to the changes in the uncertain excavation environment. This project is presented as a test case and demonstrates encouraging results for integrative modelling of large-scale problems with elements of uncertainty.

关键词： intelligent agents adaptive project management belief-desire-intention (BDI) high-level architecture (HLA) excavation project discrete event simulation Bayesian modelling uncertainty

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Cyathula prostrata:A potent source of anticancer agent against daltons ascites in swiss albino mice

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Asian Pacific Journal of Tropical Medicine 2013年第10期6卷 776-779页

作者： Priya K Krishnakumari s Vijayakumar M PsG College of Arts and science Kongunadu Arts and science College Institute of Biological science Faculty of ScienceUniversity of Malaya

Objective:To evaluate the anticancer activity of the methanolic extract of Cyathula prostrata in Ehrlich ascites carcinoma(EAC)-bearing mice with methotrexate as positive control in the advanced stage of ***:EAC was induced in swiss albino mice by injecting10~6 cell/mL of tumor cell suspension *** methanolic extract of Cyathula prostrata effect on the tumor cell viability,DNA fragmentation and MTT assay were carried ***:Methanolic extract attenuated percentage increased in the cell survival lime when compared to control ***,the effect was less than that of *** and the extracts reversed the tumor-induced alterations in UNA fragmentation and MTT ***:The present study suggests that the methanol extract of Cyathula prostrata has significant anticancer activity and that is comparable to that of methotrexate.

关键词： Antitumor Cyathula prostrata MTT Cancer Ehrlich ascites carcinoma

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Palynological investigation of a Holocene profile section from the Palaeo-Gaxun-Nur-Basin

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Chinese science Bulletin 2003年第14期48卷 1418-1422页

作者： D.Demske s.Mischke Institut f geologische Wissenschaften (Palntologie) FB Geowissenschaften Freie UniversitBerlin Malteser Str. 74-100 D 12249 Berlin Germany Institut f geologische Wissenschaften (Palntologie) FB Geowissenschaften Freie UniversitBerlin Malteser Str. 74-100 D 12249 Berlin Germany

Palynological investigations on lacustrine sediment samples revealed a general dominance of open Artemisia-Chenopodiaceae vegetation in the Palaeo-Gaxun- Nur-Basin (Inner Mongolia) between 5250 and 3500 cal. aBP. Riverside woods (Hippopha? Populus) developed between 35003250 cal. aBP and reflect moister growing conditions. During the following moist-dry transition pronounced cooling occurred around 3000 cal. aBP, in upper elevations favouring the spread of montane woods (Picea, Betula). Aridity strongly increased from 2900 to 2700 cal. aBP. The recorded vegetational and environmental changes after 3500 cal. aBP can be correlated with glacier advances in the mountains and with a humid phase in the Tengger shamo followed by desertification.

关键词：孢粉学全新世纵剖面湖泊沉积物中国内蒙古

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spatial distribution of copper content in sediments of the Yangtze River system

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Chinese science Bulletin 1997年第15期42卷 1294-1297页

作者： Zhang, Cs Zhang, s He, JB state Key Laboratory of Resources and Environment Information system China Department of Chemical Geography Institute of Geography Chinese Academy of Sciences Beijing China

THE spatial distribution pattern of an element content is controlled by various geochemical pro-cesses. studies on the spatial pattern are beneficial to further analysis on the factors. As a re-sult, our knowledge about the geochemical processes is enriched. At the same time, describingthe spatial patterns quantitatively with some indices is one way from qualitative to quantitativeanalysis.

关键词： geostatistics variogram Kriging copper.

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Antidiabetic and anti-lipemic effects of Cassia siamea leaves extract in streptozotocin induced diabetic rats

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Asian Pacific Journal of Tropical Medicine 2010年第11期3卷 871-873页

作者： s Kumar V Kumar Om Prakash Institute of Pharmaceutical sciences Kurukshetra UniversityKurukshetra -136119HaryanaIndia

Objective:To investigate the antidiabetic and anti-lipemic effects of Cassia siamea methanolic leaves ***:The antidiabetic study was performed by measuring blood glucose level with elegance glucometer at weekly intervals i.e.0,7,14 and 21 in normal and streptozotocin induced diabetic *** cholesterol,triglyceride and HDL-cholesterol were determined in normal and streptozotocin induces diabetic rats by *** was used as a reference drug at a dose of 10 mg/***:After the oral administration of extracts at doses of 250 mg/kg and 500 mg/kg for three weeks,blood glucose levels and body weights were significantly improved(Pso resulted in significantly reduction of serum cholesterol and ***-cholesterol level was found to be improved to(Psions:The Cassia siamea leaf extract is useful in controlling blood glucose level as well as improving lipid metabolism and body weight in rats with induced diabetes.

关键词： Cassia siamea Antidiabetic Anti-lipemic Rat streptozotocin

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Encryption with User Authentication Model for Internet of Medical Things Environment

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Intelligent Automation & soft Computing 2023年第1期35卷 507-520页

作者： K.s.Riya R.surendran Carlos Andrés Tavera Romero M.sadish sendil Department of Information Technology Vel Tech Multi Tech Dr.Rangarajan Dr.Sakunthala Engineering CollegeChennai600062India Center for Artificial Intelligence and Research(CAIR) Chennai Institute of TechnologyChennai600069India COMBA R&D Laboratory Faculty of EngineeringUniversidad Santiago de CaliCali76001Colombia Department of Emerging Technologies Guru Nanak Institute of TechnologyIbrahipatnam501506TelanganaIndia

Internet of Medical Things(IoMT)enabled e-healthcare has the potential to greately improve conventional healthcare services ***,security and privacy become major issues of IoMT because of the restricted processing abilities,storage,and energy constraints of the ***,it leads to infeasibility of developing traditional cryptographic solutions to the IoMT *** order to ensure security on sensitive medical data,effective encryption and authentication techniques need to be designed to assure security of the patients and healthcare service *** this view,this study designs an effective metaheuristic optimization based encryption with user authentication(EMOE-UA)technique for IoMT *** work proposes an EMOE-UA technique aims to accomplish mutual authentication for addressing the security issues and reducing the computational ***,the EMOE-UA technique employs optimal multikey homomorphic encryption(OMKHE)technique to encrypt the IoMT ***,the improved social spider optimization algorithm(IssOA)was employed for the optimal multikey generation of the MKHE *** experimental result analysis of the EMOE-UA technique takes place using benchmark data and the results are examined under various *** simulation results reported the considerably better performance of the EMOE-UA technique over the existing techniques.

关键词： User authentication security privacy internet of medical things homomorphic encryption optimal key generation

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Development of a sensitive and rapid method for quantitation of (s)-(-)- and (R)-(+)-metoprolol in human plasma by chiral LC–EsI–Ms/Ms

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Journal of Pharmaceutical Analysis 2014年第1期4卷 63-79页

作者： Primal sharma Pritesh Contractor swati Guttikar Daxesh P.Patel Pranav s.shrivastav Department of Chemistry School of Sciences Gujarat University Bioanalytical Research Department Veeda Clinical Research

A selective, sensitive and high throughput liquid chromatography-tandem mass spectro-metry （LC-EsI-Ms/Ms） method has been developed for separation and quantification of metoprolol enantiomers on a chiral Lux Amylose-2 （250 mm＆#215;4.6 mm, 5 mm） column. solid phase extraction of （s）-（-）- and （R）-（t）-metoprolol and rac-metoprolol-d6 as an internal standard （Is） was achieved on Lichrosep DVB HL cartridges employing 200 mL human plasma. Both the analytes were chromatographically separated with a resolution factor of 2.24 using 15 mM ammonium acetate in water, pH 5.0 and 0.1% （v/v） diethyl amine in acetonitrile （50：50, v/v） as the mobile phase within 7.0 min. The precursor-product ion transitions for the enantiomers and Is were monitored in the multiple reaction monitoring and positive ionization mode. The method was validated over the concentration range of 0.500-500 ng/mL for both the enantiomers. Matrix effect was assessed by post-column analyte infusion experiment and the mean extraction recovery was greater than 94.0% for both the enantiomers at all quality control levels. The stability of analytes was evaluated in plasma and whole blood under different storage conditions. The method was successfully applied to a clinical study in 14 healthy volunteers after oral administration of 200 mg metoprolol tablet under fasting conditions. The assay reproducibility is shown by reanalysis of 68 incurred samples. The suitability of the developed method was assessed in comparison with＆amp;nbsp;different chromatographic methods developed for stereoselective analysis of metoprolol in biological matrices.

关键词： s-(-)-metoprolol R-(+)-metoprolol Chiral column Chromatographicseparation LC-EsI-Ms/Ms Human plasma

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Elastic and mechanical properties of Mg3Rh intermetallic compound:An ab initio study

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Journal of Magnesium and Alloys 2016年第2期4卷 123-127页

作者： s.Boucetta G.Ugur laboratoire d’elaboration de nouveaux matériaux et caractérisations(enmc) département de physiqueuniversitéferhat abbas setif 1sétif 19000algeria faculty of science department of physicsteknikokullargazi universityankara 06500turkey

In this work, density functional theory plane-wave pseudo potential method, with local density approximation (LDA) and generalized gradientapproximation (GGA) are used to investigate the structural, elastic, mechanical and thermodynamic properties of the intermetallic compoundMg3Rh. Comparison of the calculated equilibrium lattice constants and experimental data shows very good agreement. The elastic constants weredetermined from a linear fit of the calculated stress-strain function according to Hooke’s law. From the elastic constants, the bulk modulus B, shearmodulus G, Young’s modulus E, Poisson’s ratio σ, anisotropy factor A, the ratio B/G and the hardness parameter H for Mg3Rh compound areobtained. Our calculated elastic constants indicate that the ground state structure of Mg3Rh is mechanically stable. The calculation results showthat this intermetallic crystal is stiff, elastically anisotropic and ductile material. The sound velocities and Debye temperature are also predictedfrom elastic constants. This is the first quantitative theoretical prediction of these properties.

关键词： Mg3Rh Elastic properties Mechanical properties Ab initio

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Investigation of stress corro-sion-enhanced plastic deformation using atomic force microscope

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Chinese science Bulletin 2002年第12期47卷 1053-1056页

作者： Liang, s Qiao, LJ Chu, WY Univ sci & Technol Beijing Dept Mat Phys Beijing 100083 Peoples R China

Atomic force microscope (AFM) was used to study in situ the change in slip bands during stress corrosion of brass in the ammonia solution prior to initiation of stress corrosion crack. The result showed that additive slip bands appeared ahead of a loaded notch tip during stress corrosion prior to initiation of stress corrosion crack after the constant deflection specimen was precrept for 48 h and then polished. The average height and spacing of slip bands generated during stress corrosion were about three times less or larger, respectively, than those during loading in air.

关键词： brass stress corrosion atomic force microscope.

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