Cyathula prostrata:A potent source of anticancer agent against daltons ascites in Swiss albino mice

作     者：Priya K Krishnakumari S Vijayakumar M 

作者机构：PSG College of Arts and Science Kongunadu Arts and Science College Institute of Biological ScienceFaculty of ScienceUniversity of Malaya 

出 版 物：《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志（英文版）)

年 卷 期：2013年第6卷第10期

页      面：776-779页

核心收录：

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

主　　题：Antitumor Cyathula prostrata MTT Cancer Ehrlich ascites carcinoma 

摘      要：Objective:To evaluate the anticancer activity of the methanolic extract of Cyathula prostrata in Ehrlich ascites carcinoma(EAC)-bearing mice with methotrexate as positive control in the advanced stage of ***:EAC was induced in swiss albino mice by injecting10~6 cell/mL of tumor cell suspension *** methanolic extract of Cyathula prostrata effect on the tumor cell viability,DNA fragmentation and MTT assay were carried ***:Methanolic extract attenuated percentage increased in the cell survival lime when compared to control ***,the effect was less than that of *** and the extracts reversed the tumor-induced alterations in UNA fragmentation and MTT ***:The present study suggests that the methanol extract of Cyathula prostrata has significant anticancer activity and that is comparable to that of methotrexate.