检索结果-南通市图书馆

Comparative study between intramedullary interlocking nailing and minimally invasive percutaneous plate osteosynthesis for distal tibia extra-articular fractures

引用

Chinese Journal of Traumatology 2022年第2期25卷 90-94页

作者： Kapil Mani kc Bandhu Ram Pangeni Suman Babu Marahatta Arun Sigdel amuda kc Civil Service Hospital KathmanduNepal Nepalese Army Institute of Health Sciences KathmanduNepal

Purpose:Treatment of distal tibia fractures poses significant challenge to orthopedic surgeon because of poor blood supply and paucity of soft tissue *** is considerable controversy regarding the superior option of treatment for distal tibia fracture between the minimally invasive percutaneous plate osteosynthesis(MIPPO)technique and intramedullary interlocking(IMIL)nailing for extra-articular distal tibia *** aim of our study is to compare the functional outcome between the two treatment ***:This was the prospective comparative study of 100 patients with distal third tibia fractures divided into two *** first group of patients were treated with MIPPO technique while the second group of patients were managed by IMIL *** were followed up in outpatient department to assess the functional outcomes,malunion,delayed union,nonunion,superficial and deep infection between the two *** analyses were performed using the SPSS software(version 16.0).Results:Average malunion(degrees)in the MIPPO group was 5(3—7)±1.41 vs.10.22(8—14)±2.04 in the IMIL group(p=0.001).Similarly postoperative knee pain in the IMIL group was 10%vs.2%in the MIPPO group(p=0.001).In terms of superficial infection and nonunion,the results were 8%vs.4%and 2%vs.6%for the MIPPO and IMIL group,respectively(p=0.001).Conclusion:Both procedures have shown the reliable method of fixation for distal extra-articular tibia fractures preserving the soft tissue,bony vascularity and fracture hematoma that provide a favourable biological environment for fracture *** the results of the study,we have slightly more preference for the MIPPO technique.

关键词： Distal tibia fractures IMIL nailing Maiunion MIPPO technique

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

敲低多房棘球蚴let-7-5p可抑制BALB/c小鼠腹腔巨噬细胞极化和虫体生长

引用

畜牧兽医学报 2024年第6期55卷 2619-2628页

作者：王立群吴易璇蒲桂婷曹珊菱王得先刘婷丽李红 amuda Tharheer Oluwashola 郭小腊殷宏骆学农中国农业科学院兰州兽医研究所动物疫病防控全国重点实验室/甘肃省动物寄生虫病重点实验室兰州730046 西北民族大学生命科学与工程学院兰州730030 扬州大学江苏省动物重要疫病与人兽共患病防控协同创新中心扬州225009

旨在明确敲低多房棘球蚴emu-let-7-5p对小鼠腹腔巨噬细胞极化和虫体生长的影响。构建表达多房棘球蚴emu-let-7-5p海绵序列的重组腺相关病毒载体,并在293T细胞上验证其抑制效果和特异性。70只清洁级BALB/c小鼠分别经尾静脉注射AAV8-si-le... 详细信息

旨在明确敲低多房棘球蚴emu-let-7-5p对小鼠腹腔巨噬细胞极化和虫体生长的影响。构建表达多房棘球蚴emu-let-7-5p海绵序列的重组腺相关病毒载体,并在293T细胞上验证其抑制效果和特异性。70只清洁级BALB/c小鼠分别经尾静脉注射AAV8-si-let-7-5p、AAV8-control和PBS后两周,每组随机选取2只小鼠分别用Western blot和qRT-PCR分析肝组织中GFP、let-7-5p及其靶基因C/EBP δ的表达。随后,所有小鼠每只腹腔接种1 000个原头蚴,3个月后qRT-PCR检测腹腔巨噬细胞emu-let-7-5p、C/EBP δ、M1型(IL-1β、iNOS和IL-6)和M2型(Arg-1、IL-4和IL-10)相关分子的转录水平,并统计各组小鼠多房棘球蚴的包囊重量和原头蚴数量。结果表明,注射后第15天,AAV8-si-let-7-5p成功靶向小鼠肝脏,并引起emu-let-7-5p的敲低和C/EBP δ的上调表达。感染后3个月,AAV8-si-let-7-5p组小鼠腹腔巨噬细胞emu-let-7-5p和M2型相关分子Arg-1均显著下调,而C/EBP δ和M1型相关分子IL-1β和iNOS均显著上调。此外,AAV8-si-let-7-5p组IL-4和IL-6下调表达,而IL-10上调表达,且小鼠肝脏包囊重量和原头蚴数量显著低于对照组。敲低多房棘球蚴感染小鼠体内emu-let-7-5p,可促进C/EBP δ的表达,进而抑制M2型极化和虫体生长。

关键词：多房棘球蚴 emu-let-7-5p 腹腔巨噬细胞极化虫体生长

来源：

维普期刊数据库

同方期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Subclinical hepatitis E virus genotype 1 infection:The concept of“dynamic human reservoir”

引用

World Journal of Hepatology 2024年第4期16卷 506-510页

作者： Ananta Shrestha Suresh Basnet Sudhamshu kc Department of Hepatology Alka HospitalKathmandu 44600Nepal Department of Pulmonary and Critical Care Medicine University of Maryland School of MedicineBaltimoreMD 21201United States Department of Hepatology National Academy of Medical SciencesKathmandu 44600Nepal

Hepatitis E virus(HEV)is hyperendemic in South Asia and Africa accounting for half of total Global HEV *** are eight genotypes of *** them,the four common ones known to infect humans,genotypes 1 and 2 are prevalent in the developing world and genotypes 3 and 4 are causing challenge in the industrialized *** HEV viremia in the general population,especially among blood donors,has been reported in the literature *** clinical implications related to this asymptomatic viremia are unclear and need further *** of viremia due to HEV genotype 1 infection,apparently among healthy blood donors is also reported without much knowledge about its infection ***,while HEV genotype 3 is known to be transmitted via blood transfusion in humans and has been subjected to screening in many European nations,instances of transmission have also been documented albeit without significant clinical *** of HEV genotype 1 in endemic areas often show waxing and waning *** sporadic occurrence of HEV infection interrupted by outbreaks have been frequently *** absence of known animal reservoir,where HEV exists in between outbreak is a mystery that needs further ***,occurrence of asymptomatic HEV viremia due to HEV genotype 1 during epidemiologically quiescent period may explain that this phenomenon may act as a dynamic *** HEV genotype 1 infection cannot cause chronicity,subclinical transient infection and transmission of virus might be the reason it sustains in interepidemic *** might be the similar phenomenon with SARS COVID-19 corona virus infection which is circulating worldwide in distinct phases with peaks and plateaus despite vaccination against *** view of existing evidence,we propose the concept of“Dynamic Human Reservoir.”Quiescent subclinical infection of HEV without any clinical consequences and subsequent transmission may contribute to the ex

关键词： Hepatitis E Viral hepatitis Genotype 1 Dynamic human reservoir Subclinical infection

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

An efficient framework for ensemble of natural disaster simulations as a service

引用

Geoscience Frontiers 2020年第5期11卷 1859-1873页

作者： Ujjwal kc Saurabh Garg James Hilton Discipline of ICT University of TasmaniaHobartAustralia Data61 CSIROMelbourneAustralia

Calculations of risk from natural disasters may require ensembles of hundreds of thousands of simulations to accurately quantify the complex relationships between the outcome of a disaster and its contributing *** large ensembles cannot typically be run on a single computer due to the limited computational resources *** Computing offers an attractive alternative,with an almost unlimited capacity for computation,storage,and network ***,there are no clear mechanisms that define how to implement these complex natural disaster ensembles on the Cloud with minimal time and *** such,this paper proposes a system framework with two phases of cost optimization to run the ensembles as a service over *** cost is minimized through efficient distribution of the simulations among the cost-efficient instances and intelligent choice of the instances based on pricing *** validate the proposed framework using real Cloud environment with real wildfire ensemble scenarios under different user *** experimental results give an edge to the proposed system over the bag-of-task type execution on the Clouds with less cost and better flexibility.

关键词： Wildfire prediction Ensemble simulation Cloud computing Natural disaster models

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A UNIFIED ENERGY APPROACH TO A CLASS OF MICROMECHANICS MODELS FOR MICROCRACKED SOLIDS

引用

Acta Mechanica Solida Sinica 1995年第2期8卷 110-120页

作者： HUANG, Y HWANG, kc UNIV ARIZONA DEPT AEROSP & MECH ENGNTUCSONAZ 85721 TSING HUA UNIV DEPT ENGN MECHBEIJING 100084PEOPLES R CHINA

Micromechanics models have been developed For the determination of the elastic moduli of microcracked solids based on different approaches and interpretations, including the dilute or non-interacting solution, the Mori-Tanaka method, the self-consistent method, and the generalized self-consistent method. It is shown in the present study that all these micromechanics models can be unified within an energy-equivalence framework, and that they differ only in the way in which the microcrack opening and sliding displacements are evaluated. Relevance to the differential methods and the verification of these models are discussed.

关键词： MICROMECHANICS ELASTIC MODULUS MICROCRACKED SOLID ENERGY APPROACH

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Cardiac tissue-derived extracellular matrix scaffolds for myocardial repair:advantages and challenges

引用

Regenerative Biomaterials 2019年第4期6卷 185-199页

作者： Pawan kc Yi Hong Ge Zhang Department of Biomedical Engineering The University of AkronOlson Research CenterRoom 301L260 S Forge StreetAkronOH 44325USA Department of Bioengineering University of Texas at Arlington500 UTA BlvdRoom 240ArlingtonTX 76019USA

Decellularized extracellular matrix(dECM)derived from myocardium has been widely explored as a nature scaffold for cardiac tissue engineering *** dECM offers many unique advantages such as preservation of organ-specific ECM microstructure and composition,demonstration of tissue-mimetic mechanical properties and retention of biochemical cues in favor of subsequent ***,current processes of dECM decellularization and recellularization still face many challenges including the need for balance between cell removal and extracellular matrix preservation,efficient recellularization of dECM for obtaining homogenous cell distribution,tailoring material properties of dECM for enhancing bioactivity and prevascularization of thick *** review summarizes the recent progresses of using dECM scaffold for cardiac repair and discusses its major advantages and challenges for producing biomimetic cardiac patch.

关键词： myocardial infarction decellularized extracellular matrix scaffold cardiac tissue engineering

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asymptomatic bacteriuria in pregnancy in Port Harcourt

引用

Asian Pacific Journal of Tropical Medicine 2010年第7期3卷 580-583页

作者： Odigie JO Anugweje kc Department of Pharmacology and Toxicology College of Health SciencesUniversity of Port HarcourtPort Harcourt Nigeria

Objective:To determine the prevalence of asymptomatic bacteriuria in pregnancy,to consider the antimicrobial sensitivity patterns of involved uropathogens,to elucidate the safety profiles of antibacterial agents,and to evaluate the role of urinalysis in screening for asymptomatic ***:About 760 apparently healthy pregnant subjects attending the Antenatal Clinic of the University of Port Harcourt Teaching Hospital were randomly selected for this *** and microscopy,culture,and sensitivity tests were carried out on clean-catch midstream urine samples obtained from *** reagent strips were used for urinalysis while the standard wire loop and agar diffusion technique were respectively employed for culture and susceptibility ***:A total of 111 samples yielded moderate or severe growth on culture after 48 hours comprising 35,31,27,and 18 isolates of Staphylococcus spp.,Proteus spp.,Klebsiella spp.,and Escherichia spp,*** results were positive for the presence of nitrate reductase and leucocyte esterase activity in 17 urine samples of these 111 *** isolates showed a general sensitivity to the fluorinated quinolones and to ***:The prevalence of asymptomatic bacteriuria is 14.6%, with the predominant organism being Staphylococcus *** used for treatment should have excellent fetal safety profiles,and a rapid screening test with a high negative predictive value for asymptomatic bacteriuria would be ideal.

关键词： Asymptomatic bacteriuria Leucocyte esterase Nitrate reductase Screening tests

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Structure Effect on K Shell Fluorescence Parameters at Bis-4-Bromobenzyl-1,2,4-Triazol-3-Ones

引用

光谱学与光谱分析 2016年第12期36卷 4120-4124页

作者： V.Aylιkcι Y.ünver N.Kup Aylιkcι E.Tιrasoglu K.Sancak Z.Lagap Department of Metallurgical and Materials Engineering Faculty of Technology lskenderun Technical University Department of Chemistry Faculty of ScienceKaradeniz Technical University Department of Energy Systems Engineering Faculty of Technologylskenderun Technical University University Department of Physics Faculty of SciencesKaradeniz Technical University

In this study;the effect of the electron density over the Br atoms raising with increasing number of CH_2 group using the results of the K X-ray cross-sections and average fluorescence yields of bromine in quaternary-imidazole *** the experimental set-up,50 mCi ^(241) Am source and a collimated Ultra-LEGe detector were *** electron density on the Br atoms raises according to the number of the CH_2 groups on the contrary of the inductive *** decreasing of the X-ray fluorescence parameters is interested with the increasing the electron density of Br atoms.

关键词： Cross-sections Fluorescence yields Quaternary-imidazole ring Inductive effect

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

AN INVESTIGATION ON ASYMPTOTIC NEAR-TIP FIELDS OF DYNAMIC CRACK IN AN ELASTIC-PERFECTLY PLASTIC COMPRESSIBLE MATERIAL

引用

Acta Mechanica Solida Sinica 1997年第3期10卷 198-211页

作者： Zhu, XK Hwang, kc Zhang, L TSING HUA UNIV DEPT HYDRAUL ENGNBEIJING 100084PEOPLES R CHINA TSING HUA UNIV DEPT ENGN MECHBEIJING 100084PEOPLES R CHINA

The stress and deformation fields near the tip of a mode-I dynamic crack steadily propagating in an elastic-perfectly plastic compressible material are considered under plane strain conditions. Within the framework of infinitesimal displacement gradient theory, the material is characterized by the Von Mises yield criterion and the associated J(2) flow theory of plasticity. Through rigorous mathematical analysis, this paper eliminates the possibilities of elastic unloading and continuous asymptotic fields with singular deformation, and then constructs a fully continuous and bounded asymptotic stress and strain field. It is found that in this solution there exists a parameter phi(0) which cannot be determined by asymptotic analysis but may characterize the effect of the far field. Lastly the variations of continuous stresses, velocities and strains around the crack tip are given numerically for different values of phi(0).

关键词： plane strain elastic perfectly plastic material compressibility mode-I crack dynamic propagation asymptotic field

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Uncontrolled hypertension in older patients： markers and associated factors to masked and white-coat effect

引用

Journal of Geriatric Cardiology 2016年第8期13卷 672-678页

作者： Nereida kc Lima Julio C Moriguti Eduardo Feniolli Division of General lnternal Medicine & Geriatrics Internal Medicine Department Ribeirao Preto Medical School Sao Paulo University Sao Paulo Brazil

BackgroundHypertension 是为心血管的疾病的主要风险因素，多于半老人口影响。知道他们是否有高血压的合适的控制是必要的。这研究的目的是在更旧的 *** 识别联系因素到掩盖的不受管束的高血压和假不受管束的高血压 -- 173 个个人(70.1... 详细信息

BackgroundHypertension 是为心血管的疾病的主要风险因素，多于半老人口影响。知道他们是否有高血压的合适的控制是必要的。这研究的目的是在更旧的 *** 识别联系因素到掩盖的不受管束的高血压和假不受管束的高血压 -- 173 个个人(70.1 ±； 6.7 年旧)有的血压( BP )在办公室并且由监视的回廊 BP ( ABPM )测量了与控制的组(C)的定义，有高办公室 BP 和足够的 ABPM 的个人，叫的白上衣的效果组( WCE )，不受管束( UC )，并且有给取名的适当办公室 BP 和提高的 ABPM 的题目掩盖了效果组(我)。年龄，身体团索引，糖尿病，脉搏压力(PP ) 和蘸在睡觉期间的 BP 被评估(Kruskal-Wallis 测试和逻辑回归模型).ResultsAge 比在 C 和我在 UC 是更高的(P <；0.01 ) ，并且 24-h ABPM PP 在 C 是更低的(48 ±；7 mmHg ) 并且 WCE (51 ±；6 mmHg ) 比在 UC (67 ±；12 mmHg ) 并且我(59 ±；8 mmHg )(P <；0.01 ) 。睡觉收缩 BP 蘸比在 C 在我是更低的(P = 0.03 ) 。女性与我是组的一个更大的机会被联系，它显示出在 *** 期间蘸更老的个人，的更高的 PP 和更低的 BP 办公室 BP 大小不允许将允许从我把 WCE 区分开来与 UC 组和 C 的联系因素的察觉组。ABPM 赞成了更高的 PP 和在掩盖的效果和不受管束的组蘸在睡觉期间的更低的 BP 的鉴定。

关键词：监视的回廊血压高血压掩盖的效果变老白上衣效果

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：