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Comparison between Quanti-FERON-TB Gold In-Tube test and tuberculin skin test for diagnosis of latent tuberculosis in children: A cross-section study

引用

Journal of Acute Disease 2020年第2期9卷 73-77页

作者： Keyghobad Ghadiri Alisha Akya Maryam Janatolmakan Mansour Rezaei Seyed amirabbasSharif Shahla Masoomshahi Raha Khosravi Roya chegenelorestani Infectious Diseases Research Center Kermanshah University of Medical SciencesKermanshahIran Clinical Research Development Center Imam Reza HospitalKermanshah University of Medical SciencesKermanshahIran Social Development and Health Promotion Research Center Kermanshah University of Medical SciencesKermanshahIran Infectious Diseases Research Centre Kashan University of Medical SciencesKashanIran Pediatric Pathology Research Center Research Institute for Children HealthMofid Children HospitalShahid Behehsti University of Medical SciencesTehranIran

Objective: To compare Quanti-FERON-TB Gold In-Tube (QFT-GIT) test and tuberculin skin test (TST) for the diagnosis of latent tuberculosis infection in children. Methods: In this cross-sectional study, 64 participants who were between 3 months and 14 years old and had close contact with smear-positive pulmonary tuberculosis were included. Both QFT-GIT test and TST were done and the results were analyzed by SPSS software and Kappa test. Results: The distribution of gender and age according to QFT-GIT and TST results were matched (P>0.05). Overall agreement between QFT-GIT and TST for diagnosis of latent tuberculosis infection in children was 75%. In addition, the contingency coefficient was 0.257, and the Kappa measure of agreement was 0.246 (P=0.034). Conclusions: Compared to TST, QFT-GIT shows no apparent advantage for diagnosis of latent tuberculosis infection in children.

关键词： Tuberculosis Latent tuberculosis infection Tuberculin skin test Quanti FERON

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