Comparison between Quanti-FERON-TB Gold In-Tube test and tuberculin skin test for diagnosis of latent tuberculosis in children: A cross-section study
作者机构：Infectious Diseases Research CenterKermanshah University of Medical SciencesKermanshahIran Clinical Research Development CenterImam Reza HospitalKermanshah University of Medical SciencesKermanshahIran Social Development and Health Promotion Research CenterKermanshah University of Medical SciencesKermanshahIran Infectious Diseases Research CentreKashan University of Medical SciencesKashanIran Pediatric Pathology Research CenterResearch Institute for Children HealthMofid Children HospitalShahid Behehsti University of Medical SciencesTehranIran
出 版 物：《Journal of Acute Disease》 (急性病杂志（英文版）)
年 卷 期：2020年第9卷第2期
页 面：73-77页
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题：Tuberculosis Latent tuberculosis infection Tuberculin skin test Quanti FERON
摘 要：Objective: To compare Quanti-FERON-TB Gold In-Tube (QFT-GIT) test and tuberculin skin test (TST) for the diagnosis of latent tuberculosis infection in children. Methods: In this cross-sectional study, 64 participants who were between 3 months and 14 years old and had close contact with smear-positive pulmonary tuberculosis were included. Both QFT-GIT test and TST were done and the results were analyzed by SPSS software and Kappa test. Results: The distribution of gender and age according to QFT-GIT and TST results were matched (P0.05). Overall agreement between QFT-GIT and TST for diagnosis of latent tuberculosis infection in children was 75%. In addition, the contingency coefficient was 0.257, and the Kappa measure of agreement was 0.246 (P=0.034). Conclusions: Compared to TST, QFT-GIT shows no apparent advantage for diagnosis of latent tuberculosis infection in children.
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