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Potential antioxidant properties and hepatoprotective effects of Juniperus phoenicea berries against CCl4 induced hepatic damage in rats

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Asian Pacific Journal of Tropical Medicine 2017年第3期10卷 249-255页

作者： amel Laouar Fahima Klibet Ezzeddine Bourogaa amel Benamara amel boumendjel Azzedine Chefrour Messarah Mahfoud Laboratory of Biochemistry and Environmental Toxicology Faculty of SciencesUniversity of Badji MokhtarAnnaba 23000Algeria Department of Biochemistry and Biological Cellular and Molecular Faculty of SciencesUniversity of MentouriBP 25000 ConstantineAlgeria Laboratoryof Animal Ecophysiology Faculty of SciencesSfaxSoukra road-Km 3.5BP 8023018 SfaxTunisia Department of Applied Biology Faculty of Natural Sciences and LifeUniversity of Larbi TebessiTebessa 12000Algeria Laboratory of pharmaceutical preparations for hospital use Department of PharmacyFaculty of MedicineUniversity of Badji Mokhtar-Annaba 23000Algeria Department of Biology Faculty of Natural Sciences and LifeUiversity of Mohamed Cherif MesaadiaSouk Ahras 41000Algeria

Objective:To investigate the antioxidant and hepatoprotective properties of Juniperus phoenicea(***)berries against CCl_4-induced oxidative damage in ***:Hepatotoxicity was induced in albino Wistar rats by single dose of CCl_4 dissolved in olive oil(1 mL/kg BW,1/1 in olive oil,ip).Aqueous extract of *** berries(AEJP)was administered at the dose of 250 mg/kg/day by gavage for 12 ***:Obtained results revealed that administration of CCl_4 caused a significant increase in plasma ASAT,ALAT,ALP and LDH activities and total bilirubin concentration,compared to the control ***,albumin and total protein concentration were significantly ***,a significant decrease in the level of hepatic GSH,GPx and GST activities associated with a significant increase of MDA content in CCl_4 group than those of the ***,the treatment of experimental rats with AEJP prevented these alterations and maintained the antioxidant *** histopathological observations supported the biochemical evidences of ***:The results of the present investigation indicate that *** possesses hepatoprotective activity and this effect was may be due to its antioxidant proprerties.

关键词： Juniperus phoenicea Oxydative stress Antioxydant Lipid peroxidation Hepatoprotective Biochemical parameters

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An Improved Deep Learning Framework for Automated Optic Disc Localization and Glaucoma Detection

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Computer Modeling in Engineering & Sciences 2024年第8期140卷 1429-1457页

作者： Hela Elmannai Monia Hamdi Souham Meshoul amel Ali Alhussan Manel Ayadi amel Ksibi Department of Information Technology College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Computer Sciences College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Information System College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia

Glaucoma disease causes irreversible damage to the optical nerve and it has the potential to cause permanent loss of *** ranks as the second most prevalent cause of permanent *** glaucoma diagnosis requires a highly experienced specialist,costly equipment,and a lengthy wait *** automatic glaucoma detection,state-of-the-art glaucoma detection methods include a segmentation-based method to calculate the cup-to-disc *** methods include multi-label segmentation networks and learning-based methods and rely on hand-crafted *** the optic disc(OD)is one of the key features in retinal images for detecting retinal diseases,especially for glaucoma disease *** approach presented in this study is based on deep classifiers for OD segmentation and glaucoma ***,the optic disc detection process is based on object detection using a Mask Region-Based Convolutional Neural Network(Mask-RCNN).The OD detection task was validated using the Dice score,intersection over union,and accuracy *** OD region is then fed into the second stage for glaucoma ***,considering only the OD area for glaucoma detection will reduce the number of classification artifacts by limiting the assessment to the optic disc *** this task,VGG-16(Visual Geometry Group),Resnet-18(Residual Network),and Inception-v3 were pre-trained and *** also used the Support Vector Machine *** feature-based method uses region content features obtained by Histogram of Oriented Gradients(HOG)and Gabor *** final decision is based on weighted fusion.A comparison of the obtained results from all classification approaches is *** metrics including accuracy and ROC curve are compared for each classification *** novelty of this research project is the integration of automatic OD detection and glaucoma diagnosis in a global ***,the fusion-based decision system uses the g

关键词： Optic disc glaucoma fundus image deep learning

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5G Resource Allocation Using Feature Selection and Greylag Goose Optimization Algorithm

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Computers, Materials & Continua 2024年第7期80卷 1179-1201页

作者： amel Ali Alhussan S.K.Towfek Department of Computer Sciences College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Computer Science and Intelligent Systems Research Center BlacksburgVA 24060USA

In the contemporary world of highly efficient technological development,fifth-generation technology(5G)is seen as a vital step forward with theoretical maximum download speeds of up to twenty gigabits per second(Gbps).As far as the current implementations are concerned,they are at the level of slightly below 1 Gbps,but this allowed a great leap forward from fourth generation technology(4G),as well as enabling significantly reduced latency,making 5G an absolute necessity for applications such as gaming,virtual conferencing,and other interactive electronic *** of this change are not limited to connectivity alone;it urges operators to refine their business strategies and offers users better and improved digital *** essential factor is optimization and the application of artificial intelligence throughout the general arrangement of intricate and detailed 5G *** Binary Greylag Goose Optimization(bGGO)to achieve a significant reduction in the feature set while maintaining or improving model performance,leading to more efficient and effective 5G network management,and Greylag Goose Optimization(GGO)increases the efficiency of the machine ***,the model performs and yields more accurate *** work proposes a new method to schedule the resources in the next generation,5G,based on a feature selection using GGO and a regression model that is an ensemble of K-Nearest Neighbors(KNN),Gradient Boosting,and Extra Trees *** ensemble model shows better prediction performance with the coefficient of determination R squared value equal *** proposed framework is supported by several Statistical analyses,such as theWilcoxon signed-rank *** of the benefits of this study are the introduction of new efficient optimization algorithms,the selection of features and more reliable ensemble models which improve the efficiency of 5G technology.

关键词： Optimization ensemble learning 5G technology artificial intelligence greylag goose optimization ANOVA test

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Application of Plant-Based Coagulants and Their Mechanisms in Water Treatment:A Review

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Journal of Renewable Materials 2024年第4期12卷 667-698页

作者： Abderrezzaq Benalia Kerroum Derbal Zahra Amrouci Ouiem Baatache amel Khalfaoui Antonio Pizzi Higher Normal School of Constantine Ali Mendjeli Nouvelle VilleConstantine25000Algeria Laboratory of Process Engineering for Sustainable Development and Health Products(GPDDPS) Department of Process EngineeringNational Polytechnic School of ConstantineConstantine25000Algeria Department of Environmental Engineering Laboratoire de Recherche sur le Médicament et le Développement Durable(ReMeDD)University of Salah Boubnider Constantine 3El Khroub25012Algeria Laboratory LIPE Faculty Process EngineeringUniversity of Constantine 3Ali Mendjeli Nouvelle VilleConstantine25000Algeria Laboratoire d’Etude et Recherche sur le Matériau Bois(LERMAB).Ecole Nationale Supérieure des Technologies et Industries du Bois(ENSTIB)—University of Lorraine Epinal88000France

This review describes the mechanisms of natural *** provides a good understanding of the two key processes of coagulation-flocculation:adsorption and charge neutralization,as well as adsorption and *** factors have influence the coagulation/flocculation process,including the effect of pH,coagulant dosage,coagulant type,temperature,initial turbidity,coagulation speed,flocculation speed,coagulation and flocculation time,settling time,colloidal particles,zeta potential,the effects of humic acids,and extraction density are *** bio-coagulants derived from plants are *** impact of organic coagulants on water quality,focusing on their effects on the physicochemical parameters of water,heavy metals removal,and bacteriological water quality,is *** methods of extraction and purification of plant-based coagulants,highlighting techniques such as solvent extraction and ultrasonic extraction,are *** also examines the parameters that influence these *** methods and principles of purification of coagulating agents,including dialysis,freeze-drying,ion exchange,electrophoresis,filtration,and centrifugation,are ***,it evaluates the sustainability of natural coagulants,focusing on the environmental,technical,and economic aspects of their *** the end of this review,the readers should have a comprehensive understanding of the mechanisms,selection,extraction,purification,and sustainability of plant-based natural coagulants in water treatment.

关键词： Bio-coagulants coagulating agents extraction water treatment

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Urban Electric Vehicle Charging Station Placement Optimization with Graylag Goose Optimization Voting Classifier

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Computers, Materials & Continua 2024年第7期80卷 1163-1177页

作者： amel Ali Alhussan Doaa Sami Khafaga El-Sayed M.El-kenawy Marwa M.Eid Abdelhameed Ibrahim Department of Computer Sciences College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Communications and Electronics Delta Higher Institute for Engineering and TechnologyMansoura35511Egypt Faculty of Artificial Intelligence Delta University for Science and TechnologyMansoura35712Egypt Computer Engineering and Control Systems Department Faculty of EngineeringMansoura UniversityMansoura35516Egypt

To reduce the negative effects that conventional modes of transportation have on the environment,researchers are working to increase the use of electric *** demand for environmentally friendly transportation may be hampered by obstacles such as a restricted range and extended rates of *** establishment of urban charging infrastructure that includes both fast and ultra-fast terminals is essential to address this ***,the powering of these terminals presents challenges because of the high energy requirements,whichmay influence the quality of *** the maximum hourly capacity of each station based on its geographic location is necessary to arrive at an accurate estimation of the resources required for charging *** is vital to do an analysis of specific regional traffic patterns,such as road networks,route details,junction density,and economic zones,rather than making arbitrary conclusions about traffic *** vehicle traffic is simulated using this data and other variables,it is possible to detect limits in the design of the current traffic engineering ***,the binary graylag goose optimization(bGGO)algorithm is utilized for the purpose of feature ***,the graylag goose optimization(GGO)algorithm is utilized as a voting classifier as a decision algorithm to allocate demand to charging stations while taking into consideration the cost variable of traffic *** on the results of the analysis of variance(ANOVA),a comprehensive summary of the components that contribute to the observed variability in the dataset is *** results of the Wilcoxon Signed Rank Test compare the actual median accuracy values of several different algorithms,such as the voting GGO algorithm,the voting grey wolf optimization algorithm(GWO),the voting whale optimization algorithm(WOA),the voting particle swarm optimization(PSO),the voting firefly algorithm(FA),and the voting genetic algori

关键词： Electric vehicle graylag goose optimization metaheuristics optimization machine learning

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Atypical Weight Loss in Two Patients with Schizophrenia Treated with Clozapine: A Case Report

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Open Journal of Applied Sciences 2024年第9期14卷 2544-2558页

作者： amel Kamal Mohammed Ghaday Saad Almutairi Abdulsalam Abdullah Almreef Psychiatry Department Mental Health Hospital Hafr al-Batin Saudi Arabia College of Medicine Qassim University Unizah Saudi Arabia

Clozapine is widely recognized as an effective antipsychotic medication for treatment-resistant schizophrenia, but it is typically associated with significant weight gain. This case report presents two unusual cases of patients with schizophrenia who experienced substantial weight loss while on long-term clozapine therapy. The first case involves a 35-year-old male who lost 21.3% of his initial body weight, and the second case describes a 54-year-old female who lost 30.2% of her initial weight, despite having comorbid hypothyroidism. Both patients showed improvement in psychiatric symptoms concurrent with the weight loss. Comprehensive investigations did not reveal other clear etiologies for the weight reduction. These cases challenge the conventional understanding of clozapine’s metabolic effects and highlight the potential for atypical responses in some individuals. The report discusses possible mechanisms for this unusual phenomenon, including genetic factors and altered pharmacokinetics. It also emphasizes the need for individualized monitoring and management strategies in clozapine therapy. These findings contribute to the growing body of evidence suggesting that metabolic responses to clozapine may be more complex and varied than previously thought, underscoring the importance of personalized approaches in schizophrenia treatment.

关键词： Schizophrenia Clozapine Weight Loss Treatment-Resistant Atypical Antipsychotics Metabolic Effects Case Report

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模糊数学感官评价结合响应面法优化鲊辣椒混菌发酵工艺

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食品与发酵工业 2024年第7期50卷 83-91,I0004,I0005页

作者：黄璐晗尹小庆阚建全武运戚晨晨彭芸 SAMEH Awad amel Ibrahim 杜木英西南大学食品科学学院重庆400715 西南大学中匈食品科学合作研究中心重庆400715 川渝共建特色食品重庆市重点实验室重庆400715 西藏自治区农牧科学院农产品开发与食品科学研究所西藏拉萨850032 新疆农业大学食品科学与药学学院新疆乌鲁木齐830000 新疆新康农业发展有限公司新疆乌鲁木齐830000 亚历山大大学农学院埃及亚历山大999060

以小米椒和玉米粉为原料,植物乳植杆菌XZ3和生香酵母菌Y50为菌种,制作一款混菌发酵鲊辣椒。以鲊辣椒的模糊感官评分为响应值,采用Box-Behnken中心组合设计试验对鲊辣椒混菌发酵工艺进行优化,并测定其产品的功能性成分。结果表明,混菌发... 详细信息

以小米椒和玉米粉为原料,植物乳植杆菌XZ3和生香酵母菌Y50为菌种,制作一款混菌发酵鲊辣椒。以鲊辣椒的模糊感官评分为响应值,采用Box-Behnken中心组合设计试验对鲊辣椒混菌发酵工艺进行优化,并测定其产品的功能性成分。结果表明,混菌发酵鲊辣椒的最优发酵条件为:植物乳植杆菌XZ3与生香酵母菌Y50的比例为1∶1、混菌添加量为2.5%、食盐添加量为4%、发酵时间6 d。在此优化条件下,鲊辣椒的感官评分为8.45分。与不接种自然发酵鲊辣椒和利用植物乳植杆菌XZ3纯种发酵的鲊辣椒进行对比,发现优化后的混菌发酵鲊辣椒的香气更突出。进一步测定其功能性成分发现,混菌发酵鲊辣椒中多酚组分含量最高且种类检出最多,其总酸含量、辣椒碱含量和总黄酮含量都显著高于自然发酵鲊辣椒。除此之外,相比于其他两种,混菌发酵鲊辣椒中甜味氨基酸的含量上升,苦味氨基酸的比例降低。该研究为混菌发酵鲊辣椒的生产提供了有益参考。

关键词：鲊辣椒响应面分析模糊数学感官评定发酵工艺功能性成分

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Design of Photonic Crystal Triplexer with Core-Shell Rod Defects

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Chinese Physics Letters 2015年第5期32卷 63-65页

作者： Labbani amel Benghalia Abdelmadjid Laboratory of Hyperfrequency and Semiconductors(L.H.S.) Department of ElectronicsFaculty of Technology and SciencesUniversity Mentouri Constantine 1

We investigate an optical compact triplexer based on two photonic crystal waveguides and resonant cavities. For performing wavelength selection, we use three core-shell rods as the resonant cavities. The core rods are created by introducing air holes in the center of the silicon rods. By varying the radii of the air holes, three specific wavelengths 1.31, 1.49 and 1.55μm can be obtained. This structure is designed and its performance is verified by the finite-difference time-domain method, which is highly suitable for photonic integrated circuits （PICs）. The average output transmission efficiency and quality factor are more than 98.85% and 560, respectively. The mean value of the crosstalk between output channels is about -36.49 dB. The present device is extremely compact with total size 96.24μm2, which is suitable for PICs and can be utilized in the fiber-to-the-home system.

关键词： length Design of Photonic Crystal Triplexer with Core-Shell Rod Defects

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Variations in radioactivity of phosphate rocks from different sites in Central Eastern Desert of Upper Egypt

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Nuclear Science and Techniques 2002年第4期13卷 193-201页

作者： amel-Arabi AMMYousef Physics Department Faculty of Science South Valley University 埃及 Qena

Natural radionuclides in the phosphate rock samples collected from Wadi Batur,Wadi Hegaza and Gabal Abu Had at Eastern Desert were determined using a high resolution γ-ray *** experimental results concerning ^226Ra,232Th and their daughters are *** of the measured spectra show that ^226Ra is distinguished with remarkable activities with average values ranging from 22.4 to 558Bq/kg,while ^232Th activity concentration is in the range of 9.7 to 92.8Bq/*** results of the analyses were found to be in a good agreement with the data obtained by others.

关键词：磷酸岩天然放射性核素 226Ra ^232Th

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Transmission and Reflection of Water-Wave on a Floating Ship in Vast Oceans

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Computers, Materials & Continua 2021年第6期67卷 2971-2988页

作者： amel A.Alaidrous Department of Mathematics Faculty of Applied ScienceUmm Al-Qura UniversityMakkahSaudi Arabia

In this paper,we study the water-wave flow under a floating body of an incident wave in a *** model simulates the phenomenon of waves abording a floating ship in a vast *** same model,also simulates the phenomenon of fluid-structure interaction of a large ice sheet in *** to this *** divide the region of the problem into three ***,satisfying the equation in the fluid mass and a part of the boundary conditions in each subregion,are *** obtain such solutions as infinite series including unknown *** consider a limited number only of the coefficients by truncating the infinite series and satisfy the remaining boundary conditions *** experiments show that the results are *** are given along with the graph of the system of the resulting streamlines and the dynamical pressure acting on the *** drawn system of streamlines shows the correctness of the solution and the pressure is maximum on the side facing the upstream extremity of the *** same procedure can be adequately applied for problems with more complicated geometry and other phenomenon can thus be simulated.

关键词： Potential flow linear theory fixed floating obstacle fourier transformation boundary collocation technique spectral method

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