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Applicability ＆ Readiness of Equity Crowdfunding to the Art Market in China

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Applicability ＆ Readiness of Equity Crowdfunding to the Art...

作者： alvaro flores Obieta 上海交通大学

学位级别：硕士

While Crowdfunding is a phenomenon that has been showing exponential growth in the recent years,Equity Crowdfunding is still in maturity,and its application to different industries has yet to be *** its traditional form,small investors face a long series of risks,such as illiquidity risk and information ***,the art market as investment faces many challenges and is still considered high risk,illiquid,still opaque,unregulated and disruptive features with high transaction costs and a high degree of *** a framework developed by the World Bank,this paper assesses the applicability and potential role of equity crowdfunding in the art market in China,arguing that Equity Crowdfunding in tangible assets through syndication is the best way to mitigate most of the risks related to this funding model.

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Mixed Wastes Vitrification by Transferred Plasma

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Plasma Science and Technology 2007年第6期9卷 721-724页

作者： J.TAPIA-FABELA M.pacheco-pacheco J.pacheco-SOTELO C.TORRES-REYES R.VALDIVIA-BARRIENTOS J.BENITEZ-READ R.LOPEZ-CALLEJAS F.RAMOS-flores S.BOSHLE G.ZISSIS Technological National Plasma and Energy Conversion Laboratory 118 Narbonne AveToulousecedex 4431062France

Thermal plasma technology provides a stable and long term treatment of mixed wastes through vitrification processes. In this work, a transferred plasma system was realized to vitrify mixed wastes, taking advantage of its high power density, enthalpy and chemical reactivity as well as its rapid quenching and high operation temperatures. To characterize the plasma discharge, a temperature diagnostic is realized by means of optical emission spectroscopy （OES）. To typify the morphological structure of the wastes samples~ scan- ning electron microscopy （SEM）, and X-ray diffraction （XRD） techniques were applied before and after the plasma treatment.

关键词： mixed wastes vitrification transferred plasma plasma characterisation

Pharmacokinetics of sildenafil in children with pulmonary arterial hypertension

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World Journal of Pediatrics 2017年第6期13卷 588-592页

作者： Hugo Juárez Olguín Hector Osnaya Martínez Carmen flores Pérez Blanca Ramírez Mendiola Liliana Rivera Espinosa Juan Luis Chávez pacheco Janett flores Pérez Ignacio Mora Maga(n)a Laboratory of Pharmacology National Institute of PediatricsMexico CityMexico Department of Pharmacology Faculty of MedicineNational Autonomous University of MexicoMexico CityMexico Service of Cardiology National Institute of PediatricsMexico CityMexico Laboratory of Pharmacology National Institute of PediatricsMexico CityMexico Subdirection of Teaching and Educational Programming National Institute of PediatricsMexico CityMexico

Background:Recently,sildenafil was introduced to treat pulmonary arterial hypertension (PAH);however,there are currently few studies on the pharmacokinetics of sildenalfil in ***,we aimed to carry out a pharmacokinetic study of sildenafil in children with PAH using a single ***:Twelve children diagnosed with PAH,consisting of with ten males and two females,were recruited for the study after obtaining written consent from their parents or *** samples were obtained predose and at 0.25,0.5,1,2,4,8 and 12 hours after the oral administration of 1 mg/kg of sildenafil using an extemporal pediatric formulation developed in our *** samples were analyzed using a previously validated high performance liquid chromatography ***:A pharmacokinetic analysis using the WinNonlin 3.1 program that considered the Akaike information criterion (AIC) for sdecting a more adjustable model was *** following pharmacokinetic parameters were obtained:maximal concentration (Cmax):366+179 ng/mL,time to maximal concentration:0.92±0.30 hours,elimination half-life (t1/2):2.41±1.18 hours,total clearance (CLto/F):5.85±2.81 L/hour,volume of distribution (Vd/F):20.13±14.5 L,absorption rate constants (Ka):0.343 hour-1,elimination rate (Ke):0.35 hour-1,area under curve from zero to infinity:2061±618 ng/mL/*** data of all patients adjusted to the model of one compartment were corroborated using ***:The parameters Ka,Ke and t1/2 were found to be similar to those reported in adults;however,the values of Cmax and Vd/F were significantly *** on these findings,we propose that treatment regimen of sildenafil be adjusted in children with PAH.

关键词： pharmacokinetics pulmonary arterial hypertension sildenafil

Development and Validation of a Method to Quantify Midazolam in a New Oral Formulation for Pediatric Use

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American Journal of Analytical Chemistry 2012年第8期3卷 552-558页

作者： Carmen flores Pérez Juan Luis Chávez pacheco Janett flores Pérez Hugo Juárez Olguín Blanca Ramírez Mendiola Raquel García álvarez José Francisco González Zamora ángel Changin Guerra Chocolates Turínò S.A. de C.V. Departamento de Anestesia y Quirófano INP Laboratorio de Farmacología Instituto Nacional de Pediatría (INP)

Aim: To develop an HPLC method to quantify midazolam in a new oral formulation for pediatric use. Methods: The stability of the new formulation was evaluated at different storage conditions and a preliminary assay of relative bioavailability was carried out in healthy volunteers. Results: The method of quantification was linear in the range of 5 to 60 μg·mL-1. The midazolam amount in the formulation remained stable for 90 days at 4 and 40℃ (in the dark) while at 25℃ was stable only for 14 days (exposed to light). Discussion: The relative bioavailability assay suggests that our preparation of midazolam in white chocolate reaches plasma levels similar to those induced by the apple juice formulation. Conclusion: This new white chocolate formulation masks the unpleasing flavour and has a more attractive presentation to the paediatric patient, which may be useful for children sedation and to ease its management by health carers.

关键词： Children Liquid Chromatography Magistral Formulation Midazolam

Cardiac Lesions in Naturally Infected Dogs with Trypanosoma cruzi

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Journal of Agricultural Science and Technology(A) 2011年第6期1卷 932-938页

作者： K. Y. Acosta-Viana E. Guzman-Marin M. Jimenez-Coello M. A. Torres-Leon R. F. Colin-flores A.Ortega-pacheco Laboratory of Cell Biology C.A. Biomedicine of Infectious and Parasitic Diseases Regional Research Centre ＂Dr. Hideyo Noguchi＂ Autonomous University of Yucatan Av. Itzaes # 490 Merida Yucatan Mexico Laboratory of Animal Pathology Faculty of Veterinary Medicine Autonomous University of Yucatan Merida Yucatan AP 4-116 Mexico Department of Internal Medicine and Surgery Faculty of Veterinary Medicine Autonomous University of Yucatan Merida Yucatan AP 4-116 Mexico

With the purpose to determine the frequency and type of cardiac lesions in naturally exposed dogs to Trypanosoma cruzi, ninety one stray dogs, capture by the Canine and Feline Control Center （dog pound） from the municipality of Merida, were studied. Before euthanasia, blood samples were taken to detect 72 cruzi antigens by indirect immunofluorescence antibody test and Western Blot and to detect the genome of parasite by Polymerase Chain Reaction. Immediately after euthanasia, hearts were macroscopically evaluated and a sample of the middle right atrial wall of each dog was taken for histopathological analyses. DNA was also obtained from paraffin blocks of seropositives animals with microscopic lesions to detect 72 cruzi genome. Of ninety one dogs, thirteen were seropositive. All seropositive dogs showed an association （P 〈 0.05） with lymphocytoplasmatic myocarditis. The presence of the 72 cruzi genome was also detected by PCR in cardiac septum tissue of seropositive dogs and in all the cases with microscopic lesions indicating the high pathogenicity of the local circulating strain. No association with macroscopic lesions was observed in seropositive dogs. Also, the presence of Dirofilaria immitis （D. immitis） was found in 6% of dogs evaluated. This study demonstrates a high tropism to cardiac tissue and virulence of the strains of 72 cruzi circulating in the studied dog population.

关键词： Dogs Trypanosoma cruzi IFAT PCR myocarditis.

Isolation and Characterization of Mercury Resistant Trichoderma Strains from Soil with High Levels of Mercury and Its Effects on Arabidopsis thaliana Mercury Uptake

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Advances in Microbiology 2018年第7期8卷 600-613页

作者： JoséLuis Hernández-flores JoséGerardo Bernal Melo Andrés Cruz Hernández Miguel A.Ramos López Carlos Saldana Gutiérrez Sergio Romero Gomez Victor Pérez Moreno Rosa P.Calvillo Medina JoséHumberto Valenzuela Soto Sergio pacheco Hernández George H.Jones Sergio Casas flores Juan Campos-Guillen Laboratorio de Bioseguridad y Análisis de Riesgo Departamento de Ingeniería Genética de PlantasCentro de Investigación y de Estudios Avanzados del IPNIrapuatoGto.México Facultad de Química Universidad Autónoma de QuerétaroCerro de las Campanas s/nQuerétaroQro.México Escuela de Agronomía Universidad De La Salle Bajíocampus Campestre.LeónGto.México Facultad de Ciencias Naturales Universidad Autónoma de QuerétaroAv.De las Ciencias S/NQuerétaroQro.México Centro de Investigación en Química Aplicada Blvd.Enrique Reyna Hermosillo No.140SaltilloCoahuilaMéxico Department of Biology Emory UniversityAtlantaGeorgiaUSA IPICYT División de Biología Molecular.Camino a la presa San JoséNo.2055Colonia Lomas 4a sección.C.P.San Luis PotosíMexico

Traditional mining activities are usually correlated with high levels of soil pollution, which is a major environmental concern. Extensive mining activities have taken place in the San Joaquin region in the State of Querétaro, México resulting in high levels of mercury soil pollution (up to 1532 ± 300 mg/kg). We isolated mercury-resistant fungal strains from the San Joaquin region soils and identified them through morphologic characteristics and ITS rDNA region sequence analysis. We determined that fungi isolated belong to the genus Trichoderma. All the isolates selected showed the ability to catalyze the volatilization of Hg. For air sampling, an active sampling device was constructed and using acid KMnO4 as an absorbent, the concentration of mercury in solution was determined through the cold vapor atomic absorption method. The results show mercury volatilization from the fungal species assay, with a maximum of 213.04 ± 32.6 μg/m3 while mycelium accumulation ranged from less than 17.5 ± 2.9 to 20.0 ± 3.4 μg/g. The fungal isolates were also evaluated for their ability to reduce mercury uptake in Arabidopsis thaliana. These observations suggest the utility of Trichoderma for the mobilization of mercury in those contaminated soils.

关键词： Volatilization Mercury Trichoderma Soil Bioremediation

高冲击下的保护:清除西墨西哥岛屿外来哺乳动物

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AMBIO－人类环境杂志 2008年第2期37卷 97-103页

作者： Alfonso Aguirre-Muoz Donald A.Croll C.Josh Donlan R.William Henry Ⅲ Miguel Angel Hermosillo Gregg R.Howald Bradford S.Keitt Luciana Luna-Mendoza Marlenne Rodríguez-Malagón Luz María Salas-flores Araceli Samaniego-Herrera Jose Angel Sanchez-pacheco Jacob Sheppard Bernie R.Tershy Jorge Toro-Benito Shaye Wolf Bill Wood 寒江 Grupo de Ecologíay Conservación de Islas 岛屿保护组织(IC) 高级保护战略(Advanced Conservation Strategies) 加州大学圣克鲁兹分校 IC-Canada IC Grupo de Ecología y Conservación de Islas 墨西哥联邦政府内务部

岛屿蕴含着与其面积不成比例的地球生物多样性,但是,岛屿生物多样性有很大一部分丧失了,这很大程度上是由于外来哺乳动物的冲击。幸运的是,倘若有强有力的手段防止生物灭绝、重建生态系统,那么,可以例行地清除岛屿上的外来哺乳动物。鉴... 详细信息

岛屿蕴含着与其面积不成比例的地球生物多样性,但是,岛屿生物多样性有很大一部分丧失了,这很大程度上是由于外来哺乳动物的冲击。幸运的是,倘若有强有力的手段防止生物灭绝、重建生态系统,那么,可以例行地清除岛屿上的外来哺乳动物。鉴于目前超过80%的世界主要岛群存在外来哺乳动物并且它们构成了对地球生物多样性的首要威胁,推广可重现的、可依比例缩放的行动模式以清除岛屿外来哺乳动物便十分重要了。这里我们报告过去10年来应用于西墨西哥群岛的一种成功的行动模式。非政府组织、理论生物学家、墨西哥政府机构,以及当地个人在3个群岛海进行了通力合作,产生了重大的重建成效。从26个岛屿清除了42个外来哺乳动物种群。对于每一生物群体(colony)花费21 615美元,每一分类(taxon)花费49 370美元,分别有201个海鸟群体、88个陆地特有分类得到了保护。这些保护行动的成功要归功于一种可操作的行动模式,它有3个主要的构成部分:1)将研究、重点设定、资助、公众教育、政策制定、能力建设、保护行动、监测及评估结合在一起的三国通力协作;2)主动的、专门的自然资源管理机构;3)墨西哥和美国学术研究人员的有效参与。现在需要的是:一份将所需的额外资助、能力、技术进步及政策问题综合起来的,本地区其余岛屿清除外来哺乳动物的详细计划。西墨西哥的岛屿保护提供了一种有效的方法,这种方法可以很容易地应用于其它保护努力十分有限的多岛海区域。

关键词：哺乳动物墨西哥岛屿保护清除高冲击生物多样性比例缩放

Performance and calibration of quark/gluon-jet taggers using 140 fb^(-1) of pp collisions at √s=13 TeV with the ATLAS detector

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Chinese Physics C 2024年第2期48卷 1-25页

作者： G. Aad B. Abbott K. Abeling N.J. Abicht S.H. Abidi A. Aboulhorma H. Abramowicz H. Abreu Y. Abulaiti B.S. Acharya C. Adam Bourdarios L. Adamczyk S.V. Addepalli M.J. Addison J. Adelman A. Adiguzel T. Adye A.A. Affolder Y. Afik M.N. Agaras J. Agarwala A. Aggarwal C. Agheorghiesei A. Ahmad F. Ahmadov W.S. Ahmed S. Ahuja X. Ai G. Aielli A. Aikot M. Ait Tamlihat B. Aitbenchikh I. Aizenberg M. Akbiyik T.P.A. Åkesson A.V. Akimov D. Akiyama N.N. Akolkar K. Al Khoury G.L. Alberghi J. Albert P. Albicocco G.L. Albouy S. Alderweireldt M. Aleksa I.N. Aleksandrov C. Alexa T. Alexopoulos F. Alfonsi M. Algren M. Alhroob B. Ali H.M.J. Ali S. Ali S.W. Alibocus M. Aliev G. Alimonti W. Alkakhi C. Allaire B.M.M. Allbrooke J.F. Allen C.A. Allendes flores P.P. Allport A. Aloisio F. Alonso C. Alpigiani M. Alvarez Estevez A. Alvarez Fernandez M. Alves Cardoso M.G. Alviggi M. Aly Y. Amaral Coutinho A. Ambler C. Amelung M. Amerl C.G. Ames D. Amidei S.P. Amor Dos Santos K.R. Amos V. Ananiev C. Anastopoulos T. Andeen J.K. Anders S.Y. Andrean A. Andreazza S. Angelidakis A. Angerami A.V. Anisenkov A. Annovi C. Antel M.T. Anthony E. Antipov M. Antonelli F. Anulli M. Aoki T. Aoki J.A. Aparisi Pozo M.A. Aparo L. Aperio Bella C. Appelt A. Apyan N. Aranzabal S.J. Arbiol Val C. Arcangeletti A.T.H. Arce E. Arena J-F. Arguin S. Argyropoulos J.-H. Arling O. Arnaez H. Arnold G. Artoni H. Asada K. Asai S. Asai N.A. Asbah J. Assahsah K. Assamagan R. Astalos S. Atashi R.J. Atkin M. Atkinson H. Atmani P.A. Atmasiddha K. Augsten S. Auricchio A.D. Auriol V.A. Austrup G. Avolio K. Axiotis G. Azuelos D. Babal H. Bachacou K. Bachas A. Bachiu F. Backman A. Badea P. Bagnaia M. Bahmani A.J. Bailey V.R. Bailey J.T. Baines L. Baines O.K. Baker E. Bakos D. Bakshi Gupta V. Balakrishnan R. Balasubramanian E.M. Baldin P. Balek E. Ballabene F. Balli L.M. Baltes W.K. Balunas J. Balz E. Banas M. Bandieramonte A. Bandyopadhyay S. Bansal L. Barak M. Barakat E.L. Barberio D. Barberis M. Barbero M.Z. Barel K.N. Barends T. Barillari M-S. Barisits T. Barklow P. Baron D.A. Baron Mo The ATLAS Collaboration

The identification of jets originating from quarks and gluons,often referred to as quark/gluon tagging,plays an important role in various analyses performed at the Large Hadron Collider,as Standard Model measurements and searches for new particles decaying to quarks often rely on suppressing a large gluon-induced *** paper describes the measurement of the efficiencies of quark/gluon taggers developed within the ATLAS Collaboration,using √s=13 TeV proton–proton collision data with an integrated luminosity of 140 fb^(-1) collected by the ATLAS *** taggers with high performances in rejecting jets from gluon over jets from quarks are studied:one tagger is based on requirements on the number of inner-detector tracks associated with the jet,and the other combines several jet substructure observables using a boosted decision tree.A method is established to determine the quark/gluon fraction in data,by using quark/gluon-enriched subsamples defined by the jet *** in tagging efficiency between data and simulation are provided for jets with transverse momentum between 500 GeV and 2 TeV and for multiple tagger working points.

关键词： ATLAS JET QUARK GLUON TAGGING