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Toward optical coherence tomography on a chip: in vivo three-dimensional human retinal imaging using photonic integrated circuit-based arrayed waveguide gratings

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Light(Science & Applications) 2021年第1期10卷 71-85页

作者： Elisabet A.Rank Ryan Sentosa Danielle J.harper Matthias salas Anna Gaugutz Dana Seyringer Stefan Nevlacsil Alejandro Maese-Novo Moritz Eggeling Paul Muellner Rainer hainberger Martin Sagmeister Jochen Kraft Rainer ALeitgeb Wolfgang Drexler Center for Medical Physics and Biomedical Engineering Medical University of ViennaWaehringer Guertel 18-20/4 L1090 ViennaAustria Research Centre for Microtechnology Vorarlberg University of Applied SciencesHochschulstrasse 16850 DornbirnAustria AIT Austrian Institute of Technology Gmbh Gieffinggasse 41210 ViennaAustria ams AG Tobelbader Strasse 308141 PremstaettenAustria

In this work,we present a significant step toward in vivo ophthalmic optical coherence tomography and angiography on a photonic integrated *** diffraction gratings used in spectral-domain optical coherence tomography can be replaced by photonic integrated circuits comprising an arrayed waveguide *** arrayed waveguide grating designs with 256 channels were tested,which enabled the first chip-based optical coherence tomography and angiography in vivo three-dimensional human retinal *** 1 supports a bandwidth of 22nm,with which a sensitivity of up to 91 dB(830μW) and an axial resolution of 10.7 pm was *** 2 supports a bandwidth of 48 nm,with which a sensitivity of 90 dB(480μW) and an axial resolution of 6.5μm was *** silicon nitride-based integrated optical waveguides were fabricated with a fully CMOS-compatible process,which allows their monolithic co-integration on top of an optoelectronic silicon *** a benchmark for chip-based optical coherence tomography,tomograms generated by a commercially available clinical spectral-domain optical coherence tomography system were compared to those acquired with on-chip *** similarities in the tomograms demonstrate the significant clinical potential for further integration of optical coherence tomography on a chip system.

关键词： waveguide arrayed optical

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Insecticidal Activity and Physicochemical Characterization of Nanoparticles from Foliar Extract of Capsicum chinense

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Journal of Renewable Materials 2023年第11期11卷 3933-3943页

作者： Arnoldo E.Alfaro-Corres Daniel Gonzalez-Mendoza Esau Ruiz-Sanchez Carlos Ail-Catzin Benjamin Valdez-salas Federico Gutierrez-Miceli Arturo Reyes-Ramirez Jacques Fils Pierre Division of Postgraduate Studies and Research Tecnologico Nacional de MéxicoCampus ConkalConkalYucatán97345Mexico Institute of Agricultural Sciences Universidad Autonoma de Baja CaliforniaEjido Nuevo LeonMexicaliBaja California21705Mexico Instituto de Ingeniería Universidad Autónoma de Baja CaliforniaMexicaliBaja California21100Mexico Division of Postgraduate Studies and Research Tecnologico Nacional de MexicoCampus Tuxtla GutierrezTuxtla GutierrezChiapas29050Mexico

This work was carried out to evaluate the insecticidal effect of mono,bi and trimetallic nanoparticles(NPs)from leaf extract of habanero pepper(Capsicum chinense Jacq.)on the red flour beetle(Tribolium castaneum herbst.)and cotton mealybug(Phenacoccus solenopsis Tinsley).The results showed that Cu NPs,Cu/Mn NPs and Zn/Cu NPs had high insecticidal effect against ***(63%-80% mortality after 96 h).The Cu NPs and Zn/Cu NPs showed also insecticidal effect against ***,but to a lesser extent(20%–28% after 96 h).With regards to the physicochemical characterization,Cu NPs had a zeta potential of 21.1 mV,whereas Cu/Mn NPs and Zn/Cu NPs exhibited zeta potentials of 200 *** polydispersity index(PDI)values for Cu NPs,Cu/Mn NPs,and Zn/Cu NPs were 10.1,29.16,and 14.34,*** TF-IR spectra of the NPs varied from 600 to 4000 cm−*** EDX weight percentages showed the presence of Cu(0.29%–2.4%),Mn(1.4%),and Zn(2.6%)in Cu/Mn NPs and Zn/Cu NPs,respectively.

关键词： Phytonanoparticles botanical insecticide pest control agronanotechnology

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Analysis of the Sensory and hedonic Impacts of Sweet and Bitter Tastes in Perinatally Underfed Rats

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Journal of Behavioral and Brain Science 2014年第9期4卷 423-431页

作者： Lorena Rubio-Navarro Carmen Torrero Mirelta Regalado Manuel salas Departamento de Neurobiología del Desarrollo y Neurofisiología Instituto de Neurobiología Universidad Nacional Autónoma de México Campus UNAM Juriquilla Querétaro México

Newborn rats discriminate tastes and generate gustofacial response (GFR) because the neuronal substrate is already operating. The oral application of sucrose or quinine hydrochloride produces a specific GFR. We analyzed the effects of perinatal undernutrition on the GFR development of rats at two cue concentrations. In the undernourished group, pregnant dams received different percentages of a balance diet. After birth, prenatally underfed pups continue the undernourishment by remaining for 12 h with a foster dam, and for 12 h with a nipple-ligated mother. Cues were presented as a single droplet of sucrose, sodium chloride, or quinine at low or high concentrations onto the lips at postnatal days (PDs) 1 and 3, and mouth-opening (MOF) and lip-licking frequencies (LLF) were noted. On PD 1 the undernourished group showed smaller MOF increases in response to low salt and quinine stimuli than the controls but no differences at high concentrations. On PD 3, both low and high concentrations of the sucrose and quinine cues significantly increased the MOF in the underfed compared to the control group. Low but not high salt decreased LLF on PD1 in the underfed compared to the control group. On PD 3 the undernourished pups showed significant increases of LLF with low quinine compared with the control rats, but the reverse was observed with high quinine. These data suggest that perinatal undernutrition affects the development of the sensory and hedonic aspects of taste causing changes in GFR expression.

关键词： Undernutrition Gustofacial Responses Gustatory System Development Rats

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Sweet and Bitter Tastes Evoked Different Neuronal Activation in the Rostral Portion of the Nucleus of the Solitary Tract of Developing Rats

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Journal of Behavioral and Brain Science 2012年第3期2卷 291-298页

The impact of the gustatory stimuli on the rostral portion of the nucleus of the solitary tract (rNST) was investigated in developing rats, by using c-fos immunohistochemical staining. Wistar male rats of 5, 15, and 25 days of age were isolated from the mother for 12 h, then stimulated via the intraoral route with quinine, sucrose, or NaCl, and sacrificed 90 min later. The water-stimulated group showed minimal c-fos-like immunoreactivity (FLI) compared with taste-stimulated groups that exhibited different FLI in the rNST at the different ages. At all ages the quinine-stimulated group induced FLI in the medial subfield, while sucrose induced FLI in the lateral subfield of the rNST. The intensity of FLI was highest at P15, and it declined at P25. These findings provide detailed insight into the anatomical basis of rNST activation that is involved in early food intake and the learning capacity of the newborn.

关键词： c-fos Rostral Portion of the Nucleus of the Solitary Tract Gustatory Development Rats

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Complex causes and consequences of rangeland greening in South America -multiple interacting natural and anthropogenic drivers and simultaneous ecosystem degradation and recovery trends

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Geography and Sustainability 2020年第4期1卷 304-316页

作者： Wang Li Robert Buitenwerf Renata Nicora Chequín Javier Elias Florentín Roberto Manuel salas Julia Carolina Mata Li Wang Zheng Niu Jens-Christian Svenning Center for Biodiversity Dynamics in a Changing World(BIOChANGE) Aarhus UniversityNy Munkegade 114Aarhus C 8000Denmark Section for Ecoinformatics and Biodiversity Department of BiologyAarhus UniversityNy Munkegade 114Aarhus C 8000Denmark State Key Laboratory of Remote Sensing Science Aerospace Information Research InstituteChinese Academy of SciencesBeijing 100101China Instituto de Botánica del Nordeste(CONICET-UNNE) Sargento Cabral 2131c.c.209C.P.3400Argentina University of Chinese Academy of Sciences Beijing 100049China

Land-surface greening has been reported globally over the past *** often seen to represent ecosystem recovery,the impacts on biodiversity and society can also be *** has been widely reported from rangelands,where drivers and processes are complex due to its high environmental heterogeneity and societal ***,we assess the complexity behind greening and assess its links to various drivers in an iconic,heterogeneous rangeland area,the IberáWetlands and surroundings,in ***-series satellite imagery over the past 19 years showed overall net greening,but also substantial local browning both in protected and unprotected areas,linking to land use,temporal changes in surface water,fire,and *** found substantial woody expansion mainly in the unprotected land,with 37%contributed by tree plantations and the remaining 63%by spontaneous woody expansion,along with widespread transitions from terrestrial land to seasonal surface *** occurrences tended to reduce greening with unprotected areas experiencing widespread and frequent ***,protected areas had more browning in unburnt areas than burned *** variation in annual precipitation and temperature tended to nonlinearly influence fire occurrences with an interplay of human fire management,further shaping the vegetation greening,pointing to high complexity behind the observed rangeland greening involving interactions among local *** findings highlight that the observed overall greening is an outcome of multiple trends with clear negative impacts on biodiversity and the local livestock-oriented culture(notably expanding tree plantations)and spontaneous vegetation dynamics,partly involving spontaneous woody *** latter has positive potential for biodiversity and ecosystem services in terms of woodland recovery,but can become negative in such a natural savanna region if expansions develop on a too broad scale,highlighting the importance of ensu

关键词： South America Rangeland Vegetation greening Climate change Sustainability Remote sensing

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Maternal Response of Perinatally Underfed Wistar Virgin Females Exposed to Newborn Rats

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Journal of Behavioral and Brain Science 2019年第3期9卷 78-89页

作者： Manuel salas Mirelta Regalado Carmen Torrero Minerva Ortiz-Valladares Lorena Rubio Department of Developmental Neurobiology and Neurophysiology Institute of Neurobiology National Autonomous University of Mexico Campus UNAM Juriquilla Queretaro Mexico

Nutrition plays a major role in the survival of the progeny, and its perinatal deficiencies delay physical development and interfere with social and cognitive performance later in life. The effects of early undernutrition on maternal social performance of sensitized adult virgin rats were evaluated. Several maternal and non-maternal responses were measured in virgin female Wistar rats randomly divided into two groups, control and early undernourished, during 19 days of chronic daily exposure to fresh foster pups in home-cage conditions. Underfed females (F0) received different percentages of a balanced diet during gestation. After birth, pups were underfed (F1) by alternating every 12 h between litters two lactating dams, one with ligated nipples. Weaning was at 25 days of age followed by an ad lib diet until postpartum day 90, when sensitized virgins were maternally tested daily for seven successive sessions. Significantly (p ht scores in UG F1 virgins of five different ages were observed. The UG F1 females expressed significantly (p hing, and handling shavings, with clear prolonged sniffing, retrieving and handling shaving latencies towards the foster pups compared with CG F1 sensitized females. Self-grooming was not affected, whereas exploration was significantly reduced. Current findings suggest that perinatal undernutrition interfered the organization of a core neuronal circuitry underlying the mother-litter interactions involved in social and cognitive performance of sensitized adult virgins. Furthermore, the behavioral maternal alterations in F1 virgins may possibly generate a risky negative social environment to induce cognitive and/or brain disorders in later generations.

关键词： Early Undernutrition Maternal Sensitization Cognitive Development Rats

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hypertension and obesity in living kidney donors

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World Journal of Transplantation 2021年第6期11卷 180-186页

作者： Mahmoud M Mohamed Ahmed Daoud Syed Quadri Michael J Casey Mariah Aurora Posadas salas Vinaya Rao Tibor Fülöp Karim M Soliman Department of Medicine Division of NephrologyUniversity of TennesseeMemphisTN 38163United States Department of Medicine Division of NephrologyCairo UniversityCairo 11562Egypt Department of Medicine Division of NephrologyMedical University of South CarolinaCharlestonSC 29425United States Medicine Service Ralph H.Johnson VA Medical CenterCharlestonSC 29401United States

Over the past few decades,the shortage in the kidney donor pool as compared to the increasing number of candidates on the kidney transplant waitlist led to loosening of kidney donors’acceptance *** and obesity represent risk factors for chronic kidney disease,both in native kidneys and those in kidney transplant *** great progress has been made in kidney transplantation from living donors to benefit the recipient survival and quality of life,progress has been slow to fully risk-characterize the *** review critically reassesses the current state of understanding regarding the risk of endstage kidney disease in those donors with obesity,hypertension or *** risk assessment tools need to be developed urgently to fully understand the risk glomerular filtration rate compensation failure in the remaining kidney of the donors.

关键词： Living donor Kidney Obesity hypertension Living kidney donors

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On Solvable Potentials, Supersymmetry, and the One-Dimensional hydrogen Atom

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Communications and Network 2010年第1期2卷 62-64页

作者： R. P. Martínez-y-Romero h. N. Núnez-Yépez A. L. salas-Brito 不详

The ways for improving on techniques for finding new solvable potentials based on supersymmetry and shape invariance has been discussed by Morales et al. [1] In doing so they address the peculiar system known as the one-dimensional hydrogen atom. In this paper we show that their remarks on such problem are mistaken. We do this by explicitly constructing both the one-dimensional Coulomb potential and the superpotential associated with the problem, objects whose existence are denied in the mentioned paper.

关键词： one-dimensional hydrogen atom one-dimensional Coulomb potential supersymmetric quantum mechanics.

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Biofilm and helicobacter pylori:From environment to human host

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World Journal of Gastroenterology 2014年第19期20卷 5632-5638页

作者： Apolinaria García María José salas-Jara Carolina herrera Carlos González Laboratorio de Patogenicidad Bacteriana Departamento de MicrobiologíaFacultad de Ciencias BiológicasUniversidad de ConcepciónConcepción 4030000Chile

helicobacter pylori(***)is a Gram negative pathogen that selectively colonizes the human gastric *** 50%of the world population is infected with *** reaching up to 90%of infected individuals in developing *** the increased impact upon public health care,its reservoir and the transmission pathway of the species has not been clearly established *** studies allowed the detection of *** in various aquatic environments,even forming biofilm in tap water distribution systems in several countries,suggesting a role of water as a possible reservoir of the *** persistence of human infection with *** and the resistance of clinical isolates to commonly used antibiotics in eradication therapy have been related to the genetic variability of the species and its ability to develop biofilm,demonstrated both in vivo and in vitro ***,during the last years,experimental work with this pathogen has been focused in the search for biofilm inhibitors and biofilm destabilizing ***,only two *** biofilm disrupting agents have been successfully used:Curcumin-a natural dye-and N-acetyl cysteine-a mucolytic agent used in respiratory *** main goal of this review was to discuss the evidences available in the literature supporting the ability of *** to form biofilm upon various surfaces in aquatic environments,both in vivo and in *** results published and our own observations suggest that the ability of *** to form biofilm may be important for surviving under stress conditions or in the spread of the infection among humans,mainly through natural water sources and water distribution systems.

关键词： helicobacter pylori Biofilm,Water Infection

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Estimation of Timber Production of Five Species of the Tamaulipas Thorny Shrubs Growing in Native Stands and Plantations

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Open Journal of Forestry 2014年第3期4卷 239-248页

作者： Ngangyo heya Maginot Foroughbakhch Pournavab Rahim Carrillo-Parra Artemio salas Cruz Lidia-Rosaura Department of Botany Faculty of Biological Sciences University Autonomous of Nuevo León University Town San Nicolás de los Garza Mexico Laboratory of Wood Tecnology Faculty of Forestry Sciences University Autonomous of Nuevo León Linares Mexico

Shrub species have a great capacity to develop in extreme climatic conditions;this ability has a direct influence on their development and productivity in timber and firewood. In this paper, the timber’s production of experimental plantation aged 28 years of Acacia berlandieri (Benth.), havardia pallens (Benth.) Britton & Rose, helietta parvifolia (Gray) Benth., Ebenopsis ebano (Berl.) Barneby and Acacia wrightii (Benth.) species is quantified and compared with the production of the same species developed naturally in the native bush. The variables recorded were the number of shoots per tree, total height, basal diameter and diameter at breast height of each tree to determine the volume of wood with the Smalian equation. The results indicate that the volume of usable wood was higher in experimental plantation than that on native vegetation for h. parvifolia, A. berlandieri and h. pallens. The species that produced the highest volume of timber were h. parvifolia (0.396 m3·ha-1·year-1) in plantations and E. ebano (0.118 m3·ha-1·year-1) in native shrubs, species with lower production were h. pallens (0.059 m3·ha-1·year-1) and A. berlandieri (0.052 m3·ha-1·year-1) in the native area. The highest number of shoots was registered for A. berlandieri and h. parvifolia, with eight shoots per tree in experimental plantations of both species compared with native vegetation, which was five and three shoots per tree respectively. These results high-light the importance of developing plantations in degraded areas of scrub, which can increase timber volume production.

关键词： Timber Shoots Tamaulipas Thorny Scrub Plantation Native Vegetation

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