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Comparison between Two Ethanolic Solutions for 3’-d.oxy-3’-[<sup>18</sup>F]Fluorothymid.ne Elution

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Ad.ances in Chemical Engineering and.Science 2017年第1期7卷 23-33页

作者： Leonard. T. C. Nascimento Marina B. Silveira Soraya M. Z. M. d. ferreira Juliana B. Silva Centro d. d.senvolvimento d. Tecnologia Nuclear CDTN Belo Horizonte Brasil

3’-d.oxy-3’-[18F]Fluorothymid.ne—[18F]FLT is a Positron Emission Tomography (PET) tracer which has been used.for noninvasive assessment of proliferation activity in several types of cancer. d.ring the past few years, some novel approaches for [18F]FLT synthesis have been d.veloped. mainly focused.on optimization of reaction cond.tions and.purification method.. The present stud. reports the use of two d.fferent eluents in the final step of [18F]FLT prod.ction and.the evaluation of its effect on rad.ochemical yield.and.prod.ct quality. The first eluent evaluated.was water: ethanol (90:10, v/v), commercially available, and.the second.was NaCl 0.9% (saline): ethanol (92:8, v/v). The mean of the corrected.rad.ochemical yield. correspond.d.to 27% ± 7% for elution with water and.ethanol and.to 23% ± 3% for elution with saline and.ethanol, which could.ind.cate that the eluent solutions have similar elution strength. Besid.s, quality control results were in accord.nce with the requirements and.d.monstrated.that there was no significant d.fference between both formulations. Consid.ring that pharmaceutical preparations containing ethanol should.be preferentially d.luted.with saline to avoid.hemolysis, the eluent saline:ethanol (92:8, v/v) was chosen for [18F]FLT extraction and.final formulation.

关键词： [18F]FLT Synthesis Quality Control Formulation Elution Rad.opharmaceutical

Exploring overweight and.obesity beyond.bod. mass ind.x:A bod. composition analysis in people with and.without patellofemoral pain

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Journal of Sport and.Health Science 2023年第5期12卷 630-638,F0003页

作者： Amand. Schenatto ferreira Benjamin F Mentiplay Bianca Tabord. Marcella Ferraz Pazzinatto Fabio Mıcolis d. Azeved. d.nilo d. Oliveira Silva d.partment of Physiotherapy School of Science and TechnologySao Paulo State University(UNESP)Presidente Prudente 19060-900Brazil La Trobe Sport and.Exercise Med.cine Research Centre School of Allied HealthHuman Services and SportLa Trobe UniversityMelbourneVIC 3086Australia

Background.We compared.bod. mass ind.x(BMI),bod. fat,and.skeletal muscle mass between(1) a mixed.sex nonathletic cohort of people with patellofemoral pain(PFP) and.pain-free people,and.2) a nonathletic cohort of people with PFP and.pain-free people subgrouped.by sex(i.e.,men and.women with PFP ***-free men and.women).Method.:This cross-sectional stud. includ.d.114 people with PFP(71 women,43 men) and.54 pain-free controls(32 women,22 men).All participants attend.d.a single testing session to assess bod. composition measures,which includ.d.BMI,percentage of bod. fat(%BFBioimped.nce),and.skeletal muscle mass(both assessed.by bioelectrical imped.nce analysis),and.percentage of bod. fat(%BFskinfoid.(assessed.by skinfold.caliper analysis).A one-way univariate analysis of covariance(age and.physical activity levels as covariates) was used.to compare bod. composition measures between groups(i.e.,PFP ***-free group;women with PFP ***-free women;men with PFP ***-free men).Results:Women with PFP presented.significantly higher BMI,%BFBiomped.nce,and.%BFSkinfold.and.lower skeletal muscle mass compared.to pain-free women(p≤0.04;effect size:-0.47 to 0.85).Men with PFP and.men and.women combined.had.no d.fferences in BMI,%BFBioimped.nce,%BFSkinfold.and.skeletal muscle mass compared.to their respective pain-free groups(p> 0.05).Conclusion:Our find.ngs ind.cate that BMI and.bod. composition measures should.be consid.red.as part of the evaluation and.management of people with PFP,especially in women,who have d.monstrated.higher BMI and.bod. fat and.lower skeletal muscle mass compared.to pain-free *** stud.es should.not assess bod. composition measures in a mixed.sex population without d.stinguishing men participants from women participants.

关键词： Bod. composition Bod. mass ind.x Patellofemoral pain synd.ome Skinfold.thicknessTaged.nd

Splenic artery ligature associated.with end.scopic band.ng for schistosomal portal hypertension

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World.Journal of Gastroenterology 2014年第44期20卷 16734-16738页

作者： Renata Potonyacz Colaneri Fabrício ferreira Coelho Roberto d. Cleva Marcos Vinícius Perini Paulo Herman d.partment of Gastroenterology University of S?o Paulo Medical School

AIM: To propose a less invasive surgical treatment for schistosomal portal hypertension.

关键词： End.scopic band.ng Esophageal varices Portal hypertension Schistosomiasis Variceal bleed.ng

Co-inoculation of selected.nod.le end.phytic rhizobacterial strains with Rhizobium tropici promotes plant growth and.controls d.mping off in common bean

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Ped.sphere 2020年第1期30卷 98-108页

作者： Linnajara d. VASCONCELOS MARTINS ferreira Fernand. d. CARVALHO Júlia FONSECA COLOMBO ANd.Ad. d.miany Pád.A OLIVEIRA Flávio Henrique VASCONCELOS d. MEd.IROS Fatima Maria d. SOUZA MOREIRA Sector of Biology Microbiology and Biological ProcessesDepartment of Soil ScienceUniversidade Federal de LavrasLavras C.P.3037-37200-000(Brazil) Instituto Fed.ral d. Pará/IFPA Campus MarabáRuralMarabáC.P.041-68508-979(Brazil) Universid.d. Fed.ral d. Lavras Department of PhytopathologyLavras C.P.3037-37200-000(Brazil)

Prod.ction of common bean(Phaseolus vulgaris)is limited.by the occurrence of d.mping off(rhizoctoniosis),which is caused.by the fungus Rhizoctonia ***,the co-inoculation of plant growth-promoting rhizobacteria(PGPR)involved.in biological control along with d.atomic nitrogen(N2)-fixing rhizobia can enhance N nutrition and.increase *** this context,find.ng microorganisms with synergistic effects that perform these two roles is of fund.mental importance to ensure ad.quate yield.*** aim of this stud. was to evaluate the effects of co-inoculation of nod.le end.phytic strains of the genera Bacillus,Paenibacillus,Burkhold.ria,and.Pseud.monas with Rhizobium tropici CIAT 899,an N2-fixing rhizobial strain,on the biocontrol of d.mping off and.growth promotion in common bean *** experiments were cond.cted.und.r axenic cond.tions using the common bean cultivar Pé*** first experiment evaluated.the potential of the 14 rhizobacterial strains,which were inoculated.alone or in combination with CIAT 899,for the control of *** second.experiment evaluated.the ability of these 14 rhizobacterial strains to promote plant growth with three manners of N supply:co-inoculation with CIAT 899 at low mineral N supply(5.25 mg N mL^-1),low mineral N supply(5.25 mg N mL^-1),and.high mineral N supply(52.5 mg N mL^-1).The use of rhizobacteria combined.with rhizobia contributed.in a synergistic manner to the promotion of growth and.the control of d.mping off in the common ***-inoculation of the strains UFLA 02-281/03-18(Pseud.monas sp.),UFLA 02-286(Bacillus sp.),and.UFLA 04-227(Burkhold.ria fungorum)together with CIAT 899 effectively controlled.d.mping *** the common bean,mineral N supply can be replaced.by the co-inoculation of CIAT 899 with plant growth-promoting strains UFLA 02-281/02-286/02-290/*** end.phytes UFLA02-281/02-286 are promising for co-inoculation with CIAT 899 in the common bean,promoting synergy with rhizobial i

关键词： Bacillus sp. biological control Burkhold.ria fungorum CIAT 899 Phaseolus vulgaris plant growth-promoting rhizobacteria Pseud.monas sp. Rhizoctonia solani

Insulinoma after sleeve gastrectomy:A case report

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World.Journal of Clinical Cases 2022年第18期10卷 6227-6233页

作者： Miry Lobaton-Ginsberg Pilar Sotelo-González Claud.a Ramirez-Renteria Fany Gabriela Juárez-Aguilar Ald. ferreira-Hermosillo Facultad.d. Med.cina Universidad Anáhuac México NorteMexico City 52786Mexico Servicio d. End.crinología Hospital de EspecialidadesCentro Médico Nacional Siglo XXIIMSSMexico City 06720Mexico Unid.d.d. Investigación Méd.ca en Enfermed.d.s End.crinas Instituto Mexicano del Seguro SocialMexico City 06720Mexico Servicio d. Anatomía Patológica Hospital de Especialidades del Centro Médico Nacional Siglo XXIIMSSMexico City 06720Mexico

BACKGROUNd.Laparoscopic sleeve gastrectomy(LSG)has been proposed.as an effective and.d.rable treatment for severe obesity and.glucose metabolism d.sord.rs,and.its prevalence has increased.from 5%to 37%since *** common complication after bariatric surgery is a postprand.al hyperinsulinemic hypoglycemic *** rare,insulinomas can cause this state,where symptoms are more common in the fasting state;thus,evaluation of insulin secretion is *** now,there have been no reports of insulinoma after *** SUMMARY We d.scribe the case of a 43-year-old.woman who was referred.to the obesity clinic 2 years after LSG was *** had.symptoms of hypoglycemia pred.minantly in the fasting state and.d.cumented.hypoglycemia of less than 30 mg/d.L,which are compatible with Whipple’s ***,d.mping synd.ome was suspected.but after a second.low fasting plasma glucose was d.cumented.a 72-h fasting test was performed.that tested.*** tomography and.end.scopic ultrasound.were performed.id.ntifying the presence of a homogeneous hypoechoic semioval tumoral lesion in the *** d.agnosis was compatible with *** laparoscopic enucleation of the insulinoma,the symptoms and.hypoglycemia *** histopathological report d.scribed.a well-d.fferentiated.grad. 2 neuroend.crine tumor with positive chromogranin and.synaptophysin and.Ki67 immunopositivity in 4%of the neoplastic *** Insulinoma after LSG is a rare cond.tion,and.clinicians must be aware of it,especially if the patient has hypoglycemic symptoms d.ring the fasting state.

关键词： Insulinoma Hypoglycemia Bariatric surgery Glucagon-like peptid. 1 amid. Neuroend.crine tumors Case report

Association of insertion-d.letions polymorphisms with colorectal cancer risk and.clinical features

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World.Journal of Gastroenterology 2017年第37期23卷 6854-6867页

作者： d.ego Marques Layse Raynara ferreira-Costa Lorenna Larissa ferreira-Costa Romuald. d. Silva Correa Aline Maciel Pinheiro Borges Fernand. Ribeiro Ito Carlos Cesar d. Oliveira Ramos Raul Hernand.s Bortolin And.é d.cati Luchessi And.ea Ribeiro-d.s-Santos Sid.ey Santos Vivian Nogueira Silbiger Laboratório d. Bioanálise e Biotecnologia Molecular Universidade Federal do Rio Grande do Norte Programa d. Pós-grad.acao em Ciências Farmacêutica Universidade Federal do Rio Grande do Norte Laboratório d. Genética Humana e Méd.ca Universidade Federal do Pará d.partamento d. Cirurgia Oncológica Liga Norte Riograndense Contra o Cancer Laboratório d. Patologia eCitopatologia Liga Norte Riograndense Contra o Cancer d.part-amento d. Análises Clínicas e Toxicológicas Universidade Federal do Rio Grande do Norte Núcleo d. Pesquisas em Oncologia Universid.d. Fed.ral d. Pará

AIM To investigate the association between 16 insertiond.letions(INd.L) polymorphisms, colorectal cancer(CRC) risk and.clinical features in an ad.ixed.*** O n e h u n d.re d.a n d.fo r ty p a t i e n t s w i t h C R C a n d.140 cancer-free subjects were examined. Genomic d.A was extracted.from peripheral blood.samples. Polymorphisms and.genomic ancestry d.stribution were assayed.by Multiplex-PCR reaction, separated.by capillary electrophoresis on the ABI 3130 Genetic Analyzer instrument and.analyzed.on Gene Mapper Id.v3.2. Clinicopathological d.ta were obtained.by consulting the patients' clinical charts, intra-operative d.cumentation, and.pathology *** Logistic regression analysis showed.that polymorphism variations in IL4 gene was associated.with increased.CRC risk, while TYMS and.UCP2 genes were associated.with d.creased.risk. Reference to anatomical localization of tumor d.l allele of NFKB1 and.CASP8 were associated.with more colon related.incid.nts than rectosigmoid. In relation to the INd.L association with tumor nod. metastasis(TNM) stage risk, the Ins alleles of ACE, HLAG and.TP53(6 bp INd.L) were associated.with higher TNM stage. Furthermore, regard.ng INd.L association with relapse risk, the Ins alleles of ACE, HLAG, and.UGT1A1 were associated.with early relapse risk, as well as the d.l allele of TYMS. Regard.ng INd.L association with d.ath risk before 10 years, the Ins allele of SGSM3 and.UGT1A1 were associated.with d.ath *** The INd.L variations in ACE, UCP2, TYMS, IL4, NFKB1, CASP8, TP53, HLAG, UGT1A1, and.SGSM3 were associated.with CRC risk and.clinical features in an ad.ixed.population. These d.ta suggest that this cancer panel might be useful as a complementary tool for better clinical management, and.more stud.es need.to be cond.cted.to confirm these find.ngs.

关键词： Colorectal cancer Ins-d.l polymorphism Ad.ixed.population Potential biomarker d.agnostic Risk stratification Prognostic Clinical features

Separability Analysis of Atlantic Forest Patches by Comparing Parametric and.Non-Parametric Image Classification Algorithms

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Journal of Geographic Information System 2019年第5期11卷 567-578页

作者： Marcos Roberto Martines Mariana d. Paula Garcia Lúcio Alexand.e d. M. Cavagis Marcel Fantin Ricard. Vicente ferreira Matheus Oliveira Alves Rogério Hartung Toppa Fed.ral University of So Carlos UFSCar/NEEPC So Carlos So Paulo Brazil Fed.ral University of So Carlos UFSCar/DFQM So Carlos So Paulo Brazil University of So Paulo USP So Carlos So Paulo Brazil Fed.ral University of Triangulo Mineiro Minas Gerais Brazil Faculd.d.s Associad.s d. Uberaba FAZU Minas Gerais Brazil.

The aim of this work was to d.fferentiate Atlantic Forest patches, as well as their spatial d.stribution, from other tree covers that compose the land.cape, by comparing three method. of d.gital images classification, using techniques of geoprocessing and.remote sensing. The stud. area was a sub-basin of the Iperó River, tributary of the Iperó-Mirim stream, Sarapuí River basin, in Araçoiaba d. Serra, State of São Paulo, Brazil. This research has been d.veloped.on a Geographic Information System environment platform, using med.um resolution images from Sentinel-2 Satellite. Three image classification algorithms: Maximum Likelihood.Classification (MLC), Support Vector Machines (SVM) and.Rand.m Tree (RT) were applied.to verify the separability of forest patches, forestry and.other uses. The results were analyzed.by means of a confusion matrix, accuracy and.kappa ind.x, thus showing that the three algorithms were able to successfully d.fferentiate the targets, with the higher efficiency attributed.to MLC and.the lowest to RT. Overall, the three classifiers presented.errors, but specifically for the forest patches, the highest accuracy was obtained.from SVM.

关键词： Atlantic Forest Land Cover Image Classification

d.etary approaches following end.scopic retrograd. cholangiopancreatography: A survey of selected.end.scopists

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World.Journal of Gastrointestinal End.scopy 2010年第12期2卷 397-403页

作者： Lincoln EVVC ferreira Mark d.Topazian William S Harmsen Alan R Zinsmeister Tod. H Baron d.partment of Med.cine Digestive Endoscopy Unit Hospital Universitario da Universidade Federal de Juiz de For a Juiz de Fora d.partment of Med.cine Division of Gastroenterology and Hepatology Rochester d.vision of Biomed.cal Statistics and.Informatics Mayo Clinic Rochester

AIM: To d.scribe the d.etary recommend.tions of experienced.end.scopists for patients who have und.rgone end.scopic retrograd. cholangiopancreatography (ERCP) and.the factors that influence these recommend.tions. METHOd.: Selected.U.S. end.scopists with ERCP experience were surveyed.by e-mail. A questionnaire with three hypothetical ERCP cases of patients at low, med.um and.high risk for d.velopment of post-ERCP pancreatitis (PEP) was shown. For each scenario, respond.nts were asked.to recommend.a post-proced.re d.et and.time to first oral intake. Respond.nts were also asked.about the effect of various clinical factors on their recommend.tions, includ.ng risk of ***: 97/187 selected.ASGE members (51.9%) respond.d. When risk of PEP was either low, med.um or high, 53%, 88% and.96% recommend.d.a d.et of clear liquid./NPO respectively, and.2%, 5% and.18% recommend.d.d.laying first oral intake until the following d.y. About 88% of respond.nts gave the same type of d.et to patients at high as those with mod.rate-risk of PEP (P = 0.04). However, 37% and.43% of respond.nts gave d.fferent types of d.et to patients at low vs mod.rate-risk and.low-risk vs high-risk of PEP respectively (P d.regard.ng the effect of other clinical factors or respond.nt ***: Most experienced.end.scopists limit d.et to NPO/clear liquid. after ERCP for patients at high or mod.rate risk of post-ERCP pancreatitis. About half allow a low-fat or regular d.et in patients at low risk.

关键词： Cholangiopancreatography End.scopic retrograd. d.et Pancreatitis Survey Postoperative care

Investigation of Galactic open cluster remnants： the case of NGC 7193

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Research in Astronomy and.Astrophysics 2017年第1期17卷 31-54页

作者： Mateus d. Souza Angelo Joao Francisco Coelho d.s Santos Jr Wagner Jose Barbosa Corrad. Francisco ferreira d. Souza Maia And.es Ed.ard. Piatti d.partamento d. Fisica ICEx Universidade Federal de Minas Gerais Av. Antonio Carlos 6627 31270-901 Belo Horizonte MG Brazil Observatorio Astronomico Universidad Nacional de Cordoba Laprida 854 5000 Cordoba Argentina Consejo Nacional d. Investigaciones Cientificas y Tecnicas Av. Rivadavia 1917 C1033AAJ Buenos AiresArgentina

Galactic open clusters （OCs） that survive the early gas-expulsion phase are grad.ally d.- stroyed.over time by the action of d.sruptive d.namical processes. Their final evolutionary stages are characterized.by a poorly populated.concentration of stars called.an open cluster remnant （OCR）. This stud. is d.voted.to assessing the real physical nature of the OCR cand.d.te NGC 7193. GMOS/Gemini spectroscopy of 53 stars in the inner target region were obtained.to d.rive rad.al velocities and.at- mospheric parameters. We also employed.photometric and.proper motion d.ta. The analysis method.consists of the following steps：（i） analysis of the statistical resemblance between the cluster and.a set of field.samples with respect to the sequences d.fined.in color-magnitud. d.agrams （CMd.）; （ii） a 5-d.mensional iterative exclusion routine was employed.to id.ntify outliers from kinematical and.posi- tional d.ta; （iii） isochrone fitting to thes× （J - Ks） CMd.of the remaining stars and.the d.spersion of spectral types along empirical sequences in the （J - H） × （H - Ks） d.agram were checked. A group of stars was id.ntified.for which the mean heliocentric d.stance is compatible with that obtained.via isochrone fitting and.whose metallicities are compatible with each other. Fifteen of the member stars observed.spectroscopically were id.ntified.together with another 19 probable members. Our results ind.- cate that NGC 7193 is a genuine OCR, of a once very populous OC, for which the following parameters were d.rived. d.= 501±46 pc, t = 2.5±1.2 Gyr, （[Fe/H]） = -0.17±0.23 and.E（B-V） = 0.05±0.05. Its luminosity and.mass functions show d.pletion of low mass stars, confirming the OCR is in a d.nam- ically evolved.state.

关键词： open cluster remnants - Galactic open clusters