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complex nystagmus in traumatic benign paroxysmal positional vertigo:A case study on the critical value of knowing semicircular canal excitation and inhibition patterns

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Journal of Otology 2021年第3期16卷 199-204页

作者： allison Nogi Michael c.Schubert Department of Physical Medicine and Rehabilitation Johns Hopkins University School of MedicineBaltimoreMDUSA Laboratory of Vestibular NeuroAdaptation Department of Otolaryngology-Head and Neck SurgeryJohns Hopkins School of MedicineBaltimoreMDUSA

A 73-year-old female presented to the emergency department with chief complaint of dizziness after sustaining a fall one month prior to dizziness *** careful examination of eye movement patterns during positional testing was attempted at varying stages of her inpatient admission,her complex nystagmus patterns as a result of traumatic benign paroxysmal vertigo were difficult to *** particular,the nystagmus pattern from this case suggests the BPPV was variable and affecting either 1)left posterior semicircular canal(pScc)exclusively 2)left pScc and right anterior semicircular canal,3)left and right pScc *** case illustrates the importance of two critical details;positional testing should include observing nystagmus with fixation removed and an experienced clinician should be involved as early as possible.

关键词： vertigo critical semicircular

Dimorphism of Bivalved Arthropod Branchiocaris？ Yunnanensis from the Early cambrian chengjiang Biota, South china

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Acta Geologica Sinica(English Edition) 2016年第3期90卷 818-826页

作者： WU Yu FU Dongjing ZHANG Xingliang allison c. DALEY SHU Degan Early Life Institute and State Key Laboratory of continental Dynamics Department of Geology Northwest University Xi 'an 710069 China Department of Zoology University of Oxford South Parks Road Oxford OX1 3PS UK Oxford University Museum of Natural History Parks Road Oxford OX1 3PW UK

The bivalved arthropod Branchiocaris？ yunnanensis Hou, 1987 is redescribed on the basis of new fossil material from the early cambrian chengjiang biota, South china. In total, 81 specimens have been examined. The carapace comprises two identical valves, each valve are sub-circular in outline, ranging from 24 mm to 58 mm in length, and from 15 mm to 46 mm in height. The dorsal margin is straight and bears two short cardinal spines. The valve surface is either smooth or ornamented with polygonal reticular structures, which may result from different preservation conditions. Two morphotypes have been recognized based on the presence or absence of a subdorsal swelling of the valve, which is convex dorsolaterally and extends beyond the dorsal margin when it appears. Statistic and ontogenetic analyses show both morphotypes grow isometrically and have the same growth trajectory. Therefore, the two morphotypes are interpreted as dimorphism within the same species. Our results are helpful for investigating the taxonomy and ontogeny of arthropod fossils and suggest that dimorphism might be fairly common in these early arthropods.

关键词： Arthropoda Branchiocaris Dimorphism Ontogeny chengjiang biota

Management of symptomatic neuromas:a narrative review of the most common surgical treatment modalities in amputees

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Plastic and Aesthetic Research 2022年第1期9卷 120-132页

作者： Sahand c.Eftekari Peter J.Nicksic allison J.Seitz D’Andrea T.Donnelly Aaron M.Dingle Samuel O.Poore Division of Plastic Surgery University of Wisconsin School of Medicine and Public HealthG5-347 Clinical Sciences CenterMadisonWI 53711USA

Symptomatic neuromas are an all-too-common complication following limb amputation or extremity trauma,leading to chronic and debilitating pain for *** resection of symptomatic neuromas has proven to be the superior method of intervention,but traditional methods of neuroma resection do not address the underlying pathophysiology leading to the formation of a future symptomatic neuroma and lead to high reoperation *** approaches employ the physiology of peripheral nerve injury to harness the regeneration of nerves to their *** review explores the underlying pathophysiology of neuroma formation and centralization of pain *** compares the traditional surgical approach for symptomatic neuroma resection and describes three novel surgical strategies that harness this pathophysiology of neuroma formation to their *** traditional resection of symptomatic neuromas is currently the standard of care for amputation patients,but new techniques including the regenerative peripheral nerve interface,targeted muscle reinnervation,and intraosseous transposition have shown promise in improving patient pain outcomes for postamputation pain and residual limb *** neuromas are a chronic and debilitating complication following amputation procedures and trauma,and the current standard of care does not address the underlying pathophysiology leading to the formation of the *** techniques are under development that may provide improved patient pain outcomes and a higher level of care for symptomatic neuroma resection.

关键词： Neuromas regenerative peripheral nerve interface targeted muscle reinnervation osseointegrated neural interface amputation

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Journal of Sport and Health Science 2022年第6期11卷 716-724页

作者： Zachary Yukio Kerr Avinash chandran Aliza K.Nedimyer allison E.Rothschild Melissa c.Kay Paula Gildner K.Hunter Byrd Juliet K Haarbauer-Krupa Johna K.Register-Mihalik Department of Exercise and Sport Science University of North Carolina at Chapel HillChapel HillNC 27599-8700USA Matthew Gfeller Sport-Related Traumatic Brain Injury Research center University of North CarolinaChapel HillNC 27599-8700USA Injury Prevention Research center University of North CarolinaChapel HillNC 27510USA Human Movement Science curriculum University of North CarolinaChapel HillNC 27599-8700USA Department of Health Behavior Gillings School of Public HealthUniversity of North CarolinaChapel HillNC 27599-7400USA School of Health Professions University of Southern MississippiHattiesburgMS 39406USA National center for Injury Prevention and control Centers for Disease Control and PreventionAtlantaGA 30341USA

Objective:Parents may use various information sources to obtain information about sport-related concussions(SRc).This study examined SRcrelated information sources used by parents of United States middle school children(age:10-15 years).Methods:A panel of 1083 randomly selected ***,aged≥18 years and identifying as parents of middle school children,completed an online questionnaire capturing parental and child characteristics,and utilization and perceived trustworthiness of various sources of SRc-related *** logistic regression models identified factors associated with utilizing each *** odds ratios(OR)with 95%confidence intervals(95%cIs)excluding 1.00 were deemed ***:Doctors/healthcare providers(49.9%)and other healthcare-related resources(e.g.,centers for Disease control and Prevention,WebMD)(37.8%)were common SRc-related information sources;64.0%of parents utilized≥1 of these *** sources were considered“very”or“extremely”trustworthy for SRc-related information among parents using these sources(doctors/healthcare providers:89.8%;other healthcare-related resources:70.9%).A 10-year increase in parental age was associated with higher odds of utilizing doctors/healthcare providers(adjusted odd ratio(OR_(adjusted))=1.09,95%cI:1.02-1.16)and other healthcare-related resources(OR_(adjusted)=1.11,95%cI:1.03-1.19).The odds of utilizing doctors/healthcare providers(OR_(adjusted)=0.58,95%cI:0.40-0.84)and other healthcare-related resources(OR_(adjusted)=0.64,95%cI:0.44-0.93)were lower among parents whose middle school children had concussion histories versus the parents of children who did not have concussion ***:One-third of parents did not report using doctors/healthcare providers or other healthcare-related resources for SRc-related *** associated with underutilization of these sources may be targets for future *** education for healthcare providers and e

关键词： Information seeking Media use Traumatic brain injury

complete response to radiation therapy of orbital metastasis from hepatocellular carcinoma

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World Journal of Gastroenterology 2009年第47期15卷 6000-6003页

作者： allison M Quick Mark Bloomston Edward Y Kim Nathan c Hall Nina A Mayr Department of Radiation Medicine Arthur G.James Cancer HospitalThe Ohio State University Medical CenterColumbusOH 43210 United States Department of Surgical Oncology The Ohio State University Medical CenterColumbusOH 43210 United States Department of Radiology The Ohio State University Medical CenterColumbusOH 43210United States

The incidence of hepatocellular carcinoma(Hcc)is increasing in the United States,and 50%-75%o patients with Hcc will develop metastatic disease Orbital metastases from Hcc are extremely *** report the case of a 52-year-old male with known metastatic Hcc,who presented with severe proptosis and *** orbital mass was identified on magnetic resonance imaging(MRI)and confirmed to have hypermetabolic activity on positron emission tomography/computed *** received a palliative course of external beam radiation therapy to the right *** modulated radiation therapy (IMRT)was used to allow sparing of critical norma tissues in close proximity to the *** month after completion of IMRT to 58 Gray in 30 fractions delivered over 6 wk,the patient had a complete clinical,radiologic(MRI)and symptomatic response The patient continues to have local control in the orbi 1.7 years after therapy *** critical norma structures were kept below the tolerance dose using IMRT,and no toxicities were observed.

关键词：放射治疗轨道转移肝癌反应辐射核磁共振成像正电子发射肝细胞癌

ILLUMINATION AND EXPOSITION OF A cONVEX n-DIMENSIONAL BODY DEPENDING ON ITS SHARPNESS

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Acta Mathematica Scientia 2002年第2期22卷 189-198页

作者： Boris V. Dekster Mathematics, Mount allison University, Sackville, N.B. EOA 3c0, canada Mathematics Mount Allison University Sackville N.B. E0A 3C0 Canada

A convex n-body c is said to be exposable to a set D of a few directions if there is a linear transformation L : En → En such that L(c) arid each body isometric to L(c) is illuminated by D. Denote by En the minimum integer such that each c is exposable to a (fixed) set D of cardinality En. An upper bound for En is established here.

关键词： covering illumination Hadwiger conjecture

Multi-Institutional US Experience of the Occlutech AFR Device in congenital and Acquired Heart Disease

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congenital Heart Disease 2022年第1期17卷 107-116页

作者： Barry O’callaghan Jenny Zablah Joseph Vettukattil Daniel Levi Morris Salem allison cabalka Jason Anderson Makram Ebeid Ryan Alexy Gareth J.Morgan The Heart Institute Children’s Hospital ColoradoAuroraUSA Pediatric cardiology Helen DeVos Children’s HospitalGrand RapidsUSA Pediatric cardiology UCLA HealthMattel Children’s HospitalLos AngelesUSA Pediatric cardiology UCLA Medical CentreLos AngelesUSA Pediatric cardiology Mayo ClinicRochesterUSA Pediatric cardiology University of Mississippi Medical CenterJacksonUSA Pediatric cardiology Riley Hospital for Children at Indiana University HealthIndianapolisUSA

Objectives:To detail the US multi-institutional experience with the Occlutech©(Occlutech International AB,Helsingborg,Sweden)atrial flow regulator(AFR)in children and adults with acquired or congenital heart ***:The creation of a long-term atrial communication is desirable in several cardiovascular disease phenotypes,most notably pulmonary arterial hypertension,disorders of increased left ventricular filling and increased cavopulmonary pressures in patients with a Fontan type ***:Patients were identified for inclusion from the AFR device manufacturer *** was collected using a Redcap database following IRB approval.8 weeks of follow up data was sought for each patient based on available *** was analyzed and summarized using ***:We report the experience of 6 US centers in the implantation of AFR devices in 15 patients,across a wide age range,with different disease phenotypes and a variety of *** was technically successful in all patients and improvement was noted in both clinical and hemodynamic *** were no immediate or intermediate term complications reported.3 patients died remote from *** deaths were not felt to be related to the AFR device or related procedural ***:compassionate use of the AFR device in children and adults with congenital&acquired heart disease is technically feasible and produces beneficial short term hemodynamic and symptomatic *** uptake of this technique and treatment at specialist centers has the potential to provide significant benefits to a variety of complex patients with currently limited treatment options and indeterminate prognosis.

关键词： congenital heart disease pulmonary hypertension left atrial hypertension single ventricle palliation diastolic heart failure

Models to predict injury, physical fitness failure and attrition in recruit training: a retrospective cohort study

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Military Medical Research 2020年第4期7卷 391-400页

作者： Robin M.Orr Bruce S.cohen Stephen c.allison Lakmini Bulathsinhala Edward J.Zambraski Mark Jaffrey Tactical Research Unit Bond University2 Promethean WayGold CoastRobinaQLD 4226Australia United States Army Research Institute for Environmental Medicine NatickMA 01760USA Defence Science and Technology Group Port MelbourneVIC 3207Australia

Background:Attrition rate in new army recruits is higher than in incumbent *** the current study,we identified the risk factors for attrition due to injuries and physical fitness failure in recruit training.A variety of predictive models were ***:This retrospective cohort included 19,769 Army soldiers of the Australian Defence Force receiving recruit training during a period from 2006 to *** them,7692 reserve soldiers received a 28-day training course,and the remaining 12,077 full-time soldiers received an 80-day training *** data included anthropometric measures,course-specific variables,injury,and physical fitness *** regression was used to develop a variety of models to predict the rate of attrition due to injuries and physical fitness *** area under the receiver operating characteristic curve was used to compare the performance of the ***:In the overall analysis that included both the 28-day and 80-day courses,the incidence of injury of any type was 27.8%.The 80-day course had a higher rate of injury if calculated per course(34.3%vs.17.6%in the 28-day course),but lower number of injuries per person-year(1.56 vs.2.29).Fitness test failure rate was significantly higher in the 28-day course(30.0%vs.12.1%).The overall attrition rate was 5.2%and 5.0%in the 28-day and 80-day courses,*** fracture was common in the 80-day course(n=44)and rare in the 28-day course(n=1).The areas under the receiver operating characteristic curves for the course-specific predictive models were relatively low(ranging from 0.51 to 0.69),consistent with"failed"to"poor"predictive *** course-combined models performed somewhat better than the course-specific models,with two models having AUc of 0.70 and 0.78,which are considered"fair"predictive ***:Attrition rate was similar between 28-day and 80-day *** comparison to the 80-day full course,the 28-day course had a lower rat

关键词： Military training Predictive modelling Risk management Soldier

Outcomes after arthroscopic repair of rotator cuff tears in the setting of mild to moderate glenohumeral osteoarthritis

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World Journal of Orthopedics 2022年第7期13卷 631-643页

作者： Ian S Hong allison J Rao Tyler L carlLee Joshua D Meade Daniel J Hurwit Gregory Scarola David P Trofa Shadley c Schiffern Nady Hamid Patrick M connor James E Fleischli Bryan Michael Saltzman Department of Orthopedic Surgery Atrium Health Musculoskeletal InstituteCharlotteNC 28207United States Department of Sports Medicine Orthocarolina Research InstituteCharlotteNC 28207United States Department of Orthopedic Surgery Columbia University Irving Medical CenterNew York CityNY 10032United States Department of Orthopaedic Surgery Carolinas Medical CenterCharlotteNC 28207United States Department of Orthopedic Surgery OrthoCarolina Sports Medicine CenterCharlotteNC 28207United States

BAcKGROUND Rotator cuff pathology is a very common source of shoulder ***,osteoarthritis of the glenohumeral joint can cause shoulder pain and produce similar *** management can be indicated for both pathologies,however,outcomes data is limited when examining rotator cuff repair(RcR) in the setting of glenohumeral arthritis(GHOA).Thus,this study sought to determine outcomes for patients who undergo RcR in the setting of *** To evaluate if a relationship exists between outcomes of RcR in the setting of *** This was a retrospective analysis of patients who underwent arthroscopic rotator cuff repair with concurrent glenohumeral osteoarthritis between *** were stratified based on rotator cuff tear size and glenohumeral osteoarthritis *** were paired 1:1 with patients without glenohumeral *** included had a minimum two year *** of conversion to total shoulder arthroplasty,complication rates following initial surgery,and patient-reported outcome measures were *** A total of 142 patients were *** number of patients that required total shoulder arthroplasty within two years after index surgery was low.2/71(2.8%) patients with GHOA,and 1/71(1.4%) without *** rotator cuff repair,both groups showed favorable patientreported *** Patients with glenohumeral osteoarthritis who underwent arthroscopic rotator cuff repair showed comparable outcomes to patients without glenohumeral osteoarthritis.

关键词： Rotator cuff repair Rotator cuff tear Glenohumeral osteoarthritis Shoulder Arthroscopic Outcomes