检索结果-南通市图书馆

Impact of gender-affirming hormone therapy on the development of COVID-19 infections and associated complications:A systematic review

引用

World Journal of Methodology 2022年第6期12卷 465-475页

作者： Jennifer J Ferraro allie reynolds Sylvia Edoigiawerie Michelle Y Seu Sydney R Horen Amir Aminzada Alireza Hamidian Jahromi Department of Surgery Division of Plastic and Reconstructive SurgeryRush University Medical CenterChicagoIL 60612United States Undergraduate Studies Princeton UniversityPrincetonNJ 08544United States Medical School The University of Chicago Pritzker School of MedicineChicagoIL 60637United States Division of Plastic and Reconstructive Surgery Temple University Health SystemPhiladelphiaPA 19140United States

BACKGROUND Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)can produce a wide range of clinical manifestations from asymptomatic to *** researchers have worked to elucidate the pathogenic mechanisms underlying these variable *** in individual responses to systemic inflammation and coagulopathy appear to be modulated by several factors,including sex steroid *** men or non-binary individuals who undergo gender-affirming hormone therapy(GAHT)are a unique population of interest for exploring the androgen-mediated coronavirus disease 2019(COVID-19)*** the search for reliable and effective COVID-19 treatments continues,understanding the risks and benefits of GAHT may mitigate COVID-19 related morbidity and mortality in this patient *** To investigate the potential role of GAHT in the development of COVID-19 infections and *** This systematic review implemented an algorithmic approach using PRISMA ***,Scopus,Google Scholar top 100 results,and archives of Plastic and Reconstructive Surgery was on January 12,2022 using the key words“gender”AND“hormone”AND“therapy”AND“COVID-19”as well as associated ***-English articles,articles published prior to 2019(prior to COVID-19),and manuscripts in the form of reviews,commentaries,or letters were *** of the selected publications were screened as *** The database search resulted in the final inclusion of 14 studies related to GAHT *** the included studies,only two studies directly involved and reported on COVID-19 in transgender *** clinical trials looked at the relationship between testosterone,estrogen,and progesterone in COVID-19 infected cis-gender men and *** has been proposed that androgens may facilitate initial COVID-19 infection,however,once this occurs,testosterone may have a protective *** clinical studies have shown that low baseline t

关键词： COVID-19 Transgender Gender-affirming hormone therapy Gender affirmation Testosterone Estrogen

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Associations between SARS-CoV-2 infections and thrombotic complications necessitating surgical intervention:A systematic review

引用

World Journal of Methodology 2022年第6期12卷 476-487页

作者： Jennifer J Ferraro allie reynolds Sylvia Edoigiawerie Michelle Y Seu Sydney R Horen Amir Aminzada Alireza Hamidian Jahromi Division of Plastic and Reconstructive Surgery Department of SurgeryRush University Medical CenterChicagoIL 60612United States Medical School University of ChicagoChicagoIL 60637United States Department of Surgery Temple University HospitalPhiladelphiaPA 19140United States

BACKGROUND Several unique clinical features of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),the cause of coronavirus disease 2019(COVID-19)infection,have been identified and *** such feature,mostly among patients with severe COVID-19 infection,has become known as COVID-19-induced *** patients with a history of or active COVID-19 infection bear a significantly higher risk for postoperative thrombotic *** patients may require surgical intervention to treat severe thrombotic *** studies have been carried out to better characterize this *** purpose of this study was to perform a systematic review and meta-analysis of the literature on COVID-19 infections that led to thrombotic complications necessitating surgical *** hypothesized that patients with recent or active COVID-19 infection would have high rates of thromboembolic complications both arterial and venous in *** To perform a systematic review and meta-analysis of the literature on COVID-19 infections that led to thrombotic complications necessitating surgical *** The current systematic review implemented an algorithmic approach to review all the currently available English medical literature on surgical interventions necessitated by COVID-19 thrombotic complications using the preferred reporting items for systematic reviews and metaanalysis principles.A comprehensive search of the medical literature in the“PubMed”,“Scopus”,“Google Scholar”top 100 results,and archives of Plastic and Reconstructive Surgery was performed using the key words“COVID-19”AND“surgery”AND“thromboembolism”AND“complication”.The search string was generated and the records which were not specific about surgical interventions or thrombotic complications due to COVID-19 infection were *** and abstracts were screened by two authors and full-text articles were assessed for eligibility and ***,results

关键词： Thromboembolic COVID-19 SARS-CoV-2 Surgical intervention Complications Surgery

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano-STING agonist-decorated microrobots boost innate and adaptive anti-tumor immunity

引用

Nano Research 2023年第7期16卷 9848-9858页

作者： Yixin Wang Zhaoting Li Yu Chen allie Barrett Fanyi Mo Quanyin Hu Pharmaceutical Sciences Division School of PharmacyUniversity of Wisconsin-MadisonMadisonWI 53705USA Carbone Cancer Center School of Medicine and Public HealthUniversity of Wisconsin-MadisonMadisonWI 53705USA Wisconsin Center for NanoBioSystems School of PharmacyUniversity of Wisconsin-MadisonMadisonWI 53705USA

Activating the cyclic guanosine monophosphate-adenosine monophosphate synthase/stimulator of interferon genes(cGAS/STING)signaling has emerged as a promising anti-tumor strategy due to the important role of the pathway in innate and adaptive immunity,yet the selective delivery of STING agonists to tumors following systemic administration remains ***,we develop a nano-STING agonist-decorated microrobot platform to achieve the enhanced anti-tumor *** ions and the STING agonist 2’3’-cyclic guanosine monophosphate-adenosine monophosphate(cGAMP)are co-encapsulated in the mitochondria-targeting nanoparticles(mTNPs),which can trigger the release of mitochondrial DNA(mtDNA)by Fenton reactioninduced mitochondria oxidative *** exogenous cGAMP and the endogenous mtDNA can work synergistically to induce potent cGAS/STING signaling ***,we decorate mTNPs onto Salmonella typhimurium VNP20009(VNP)bacteria to facilitate tumor accumulation and deep *** demonstrate that the systemic administration of this microrobot activates both innate and adaptive immunity,improving the immunotherapeutic efficacy of the STING agonists.

关键词： drug delivery mitochondrial DNA(mtDNA) Fenton reaction stimulator of interferon genes(STING) tumor immunotherapy bacteria

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Living Life Well--You can save a life： How to perform the Heimlich maneuver

引用

空中英语教室（高级版．彭蒙惠英语） 2016年第12期 9-11,39,40页

作者： allie Shah

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Clinical outcomes in patients with native valve infective endocarditis and diabetes mellitus

引用

World Journal of Cardiology 2021年第1期13卷 11-20页

作者： Temidayo Abe Harry Onoriode Eyituoyo Gabrielle De allie Titilope Olanipekun Valery Sammah Effoe Kikelomo Olaosebikan Paul Mather Department of Internal Medicine Morehouse School of MedicineAtlantaGA 30310United States Department of Internal Medicine Mercer University School of MedicineMaconGA 31207United States Department of Cardiovascular Disease Morehouse School of MedicineAtlantaGA 30310United States Department of Medicine University of Debrecen Medical and Health Science CenterDebrecen 4032Hungary Department of Cardiovascular Disease University of PennsylvaniaPennsylvaniaPA 19104United States

BACKGROUND There is a lack of data on the clinical outcomes in patients with native valve infective endocarditis(NVIE)and diabetes mellitus(DM).AIM To investigate(1)trends in the prevalence of DM among patients with NVIE;and(2)the impact of DM on NVIE *** We identified 76385 with NVIE from the 2004 to 2014 National Inpatient Sample,of which 22284(28%)had *** assessed trends in DM from 2004 to 2014 using the Cochrane Armitage *** compared baseline comorbidities,microorganisms,and in-patients procedures between those with vs without *** match analysis and multivariate logistic regression were used to investigate study outcomes in in-hospital mortality,stroke,acute heart failure,cardiogenic shock,septic shock,and atrioventricular *** Crude rates of DM increased from in 22%in 2004 to 30%in *** were significant differences in demographics,comorbidities and NVIE risk factors between the two *** aureus was the most common organism identified with higher rates in patients with DM(33.1%vs 35.6%;P<0.0001).After propensity matching,in-hospital mortality(11.1%vs 11.9%;P<0.0001),stroke(2.3%vs 3.0%;P<0.0001),acute heart failure(4.6%vs 6.5%;P=0.001),cardiogenic shock(1.5%vs 1.9%;P<0.0001),septic shock(7.2%vs 9.6%;P<0.0001),and atrioventricular block(1.5%vs 2.4%;P<0.0001),were significantly higher in patients with *** predictors of mortality in NVIE patients with DM include hemodialysis,congestive heart failure,atrial fibrillation,staphylococcus aureus,and older *** There is an increasing prevalence of DM in NVIE and it is associated with poorer *** studies are crucial to identify the clinical,and sociodemographic contributors to this trend and develop strategies to mitigate its attendant risk.

关键词： Infective endocarditis Native valve infective endocarditis Diabetes mellitus Valvular heart disease Cardiovascular disease National Inpatient Sample

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

外国直接投资对塞拉利昂全要素生产率增长影响的实证研究

外国直接投资对塞拉利昂全要素生产率增长影响的实证研究

引用

作者： NANAH JUSTICIA allie 江苏大学

学位级别：硕士

尽管有关外商直接投资（FDI）对本国经济发展的影响研究很多,但这些问题仍然受到越来越多关注。不过这些研究可能还需进一步完善,一方面,许多提案建议在财务交接时已经通过吸引外国直接投资而获利的政府,东亚和东南亚国家政府的经济发... 详细信息

尽管有关外商直接投资（FDI）对本国经济发展的影响研究很多,但这些问题仍然受到越来越多关注。不过这些研究可能还需进一步完善,一方面,许多提案建议在财务交接时已经通过吸引外国直接投资而获利的政府,东亚和东南亚国家政府的经济发展水平是不可忽视的重要因素之一。在此理论中,东道国经济创新可通过多种方式带来生产率增长,例如,可以为邻近企业从偏远企业发展现成工作的人员调整,培训/观察/示范,以及通过提供输入进行沟通。在技术限制的背景下,应考虑东道国的经济生存能力,就其规模而言,应通过全要素生产率（TFP）单位中的几个质量要素来确定。首先,按照一般性做法,使用1990年至2018年的时间序列数据,例如,使用JJ协整检验对ADF和PP-Fisher装置的根进行一次单独的集成检验,研究表明可以与类似的应用程序（例如I（1））组合使用,并且可以集成在一起（表示长期关系）。使用VECM方法估计的全要素生产率（TFP）表明,对外商直接投资较多的塞拉利昂而言,本研究中的所有要素都与其全要素生产率（TFP）正相关。特别地,外商直接投资对全要素生产率产生的积极影响,不能通过采用和调整新的速度来促进创新溢出。为了进一步探究因果关系,本文采用VECM模型进行格兰杰因果关系检验,结果表明,在过去FDI,TR,FD与TFP之间具有单向因果关系,但现在仅FDI与TFP之间存在双边因素,这表明外商直接投资状况的改善影响了塞拉利昂的全要素生产率（TFP）。最后,由于外商投资的阻力,本文分析了塞拉利昂经济增长的脉冲响应函数（IRF）以确保全要素生产率对外国直接投资的响应。根据以上与研究目标相一致的发现,本研究建议继续吸引高质量和技术密集的外国直接投资。应该指出的是,至少并没有那么多的外国直接投资,而是所涉及的外国直接投资行使了能效覆盖水平,该水平决定了外国直接投资与利润发展关系的质量和管理能力。塞拉利昂力求通过直接的外部竞争的溢出效应来提高整体效率,因为这是促进技术发展的运营过程。这样,塞拉利昂可能会通过专业管理和培训来支持外部获利组织,以在企业层面发展外国直接投资的积极外部收益和溢出收益。

关键词：外商直接投资全要素生产率向量误差修正模型塞拉利昂

来源：

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

加载模式与夹具对环氧沥青混合料疲劳性能检测的影响

引用

重庆交通大学学报（自然科学版） 2010年第6期29卷 891-895页

作者： allie Y.Mansaray 黄明同济大学道路与交通工程教育部重点实验室上海201804

环氧沥青混合料的疲劳评价是环氧钢桥面铺装的主要检测项目之一。通过三分点小梁疲劳与跨中加载小梁疲劳2种方案,对比了应变控制与应力控制对于环氧沥青混合料的疲劳评价的适用性;用2种常见环氧沥青的对比试验数据,印证了分析,推荐使用... 详细信息

环氧沥青混合料的疲劳评价是环氧钢桥面铺装的主要检测项目之一。通过三分点小梁疲劳与跨中加载小梁疲劳2种方案,对比了应变控制与应力控制对于环氧沥青混合料的疲劳评价的适用性;用2种常见环氧沥青的对比试验数据,印证了分析,推荐使用应力控制;通过ANSYS有限元分析,对疲劳夹具进行了修正,确保其疲劳试验数据的准确性。

关键词：环氧沥青混合料疲劳性能应变控制应力控制

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Nikola引擎盖下的秘密

引用

商业周刊（中文版） 2022年第18期 62-69页

作者： allie Conti 不详

鲍勃·辛普森(Bob Simpson)蹲在角落里,等待给他的信号。当覆盖在那台卡车上的丝绸终于滑落下来,这位工程师急忙走到幕布后面,爬到舞台下方插上电源线。

关键词：电源线引擎盖工程师辛普森

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Current Status of <i>M. hyopneumoniae</i>in Pigs in Grenada, West Indies

引用

Open Journal of Veterinary Medicine 2017年第7期7卷 77-84页

作者： Traci M. Vogler Sachin Kumthekar Keshaw Tiwari Claude De allie Ravindra Nath Sharma Department of Pathobiology School of Veterinary Medicine St. George’s University Grenada West Indies

Mycoplasma hyopneumoniae, cause of enzootic pneumonia is known for serious economic losses in pigs. The disease is prevalent all over the world. There is no published report on Mycoplasma hyopneumoniae incidence in Grenadian pigs. The aim of this study was to estimate seroprevalence of antibodies for Mycoplasma hyopneumoniae in non vaccinated pigs in Grenada. Sera were collected randomly from 459 pigs of all ages from all six parishes of Grenada. Sera were tested for antibodies to Mycoplasma hyopneumoniae using an indirect Enzyme Linked Immunosorbant Assay (ELISA) kit. Antibodies to Mycoplasma hyopneumoniae were found in 8.71% (95% CI: 0.0644 to 0.1167) pigs. The greatest percent of positives (62.5%) (95% CI: 0.4699 to 0.7582) were in youngest group 22.5% (95% CI: 0.1211 to 0.3771) in >2 year. Positive females were overrepresented compared to males by 3:1. This is the first report on the sero-prevalence of Mycoplasma hyopneumoniae in pigs from Grenada, West Indies.

关键词： Grenada Mycoplasma hyopneumoniae Pigs Seroprevalence

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

开普敦是我家

引用

疯狂英语（新悦读） 2016年第7期 42-44页

作者： Mohammed allie Wendy

提起开普敦，你的脑子大概会一片空白——它可能只是地理课上闪过的一个地名，又或是旅游宣传资料上关于好望角的介绍。其实，开普敦是一个很有趣的城市，快来听听“地胆”的介绍吧。

关键词：开普敦宣传资料地理课好望角旅游城市

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：