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Prostaglandin E1 administration post liver transplantation and renal outcomes:A retrospective single center experience

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World Journal of Transplantation 2024年第4期14卷 101-109页

作者： Vinay Jahagirdar Mohamed Ahmed Ifrah Fatima Hassam Ali Laura Alba John H Helzberg Lee S Cummings Matthew Wilkinson Jameson Forster alisa likhitsup Department of Internal Medicine Saint Luke’s Health System of Kansas City and the University of Missouri-Kansas CityKansas CityMO 64111United States Department of Gastroenterology and Hepatology East Carolina University Brody School of MedicineGreenvilleNC 27834United States Division of Internal Medicine Department of Gastroenterology and HepatologySaint Luke’s Health System of Kansas City and University of Missouri-Kansas CityKansas CityMO 64111United States Department of Surgery University of Missouri-Kansas City and Transplant SurgerySaint Luke’s Hospital of Kansas CityKansas CityMO 64111United States Department of Gastroenterology and Hepatology University of MichiganAnn ArborMI 48109United States

BACKGROUND Prostaglandin E1(PGE1),or alprostadil,is a potent vasodilator that improves hepatic blood flow and reduces ischemia-reperfusion injury post-liver transplantation(LT).However,the benefits of PGE1 on renal function after LT have not yet been well *** To assess the impact of PGE1 administration on renal function in patients who underwent liver or liver-kidney *** This retrospective study included all patients who underwent liver or liverkidney transplant at our institution from January,2011 to December,*** were classified based on whether they received ***1 was administered post-LT to those with transaminases>1000 U/L in the immediate postoperative ***,post-LT treatments and/or complications,renal function,and survival were *** logistic regression analysis was performed,and a two-tailed P value<0.05 was considered statistically *** A total of 145 patients underwent LT,with 44(30%)receiving *** patient characteristics were comparable,except the PGE1 group had significantly higher aspartate aminotransferase(AST)(1961.9 U/L±1862.3 U/L vs 878 U/L±741.4 U/L,P=0.000),alanine aminotransferase(1070.6 U/L±895 U/L vs 547.7 U/L±410 U/L,P=0.000),international normalized ratio on post-LT day 1(2±0.74 vs 1.8±0.4,P=0.03),a longer intensive care unit stay(8.1 days±11.8 days vs 3.8 days±4.6 days,P=0.003),more vasopressor use(55.53 hours±111 hours vs 16.33 hours±26.3 hours,P=0.002),and higher immediate postoperative complications(18.6%vs 4.9%,P=0.04).The PGE1 group also had a significantly higher 90-day readmission rate(29.6%vs 13.1%,P=0.02)and lower 1-year liver graft survival(87.5%vs 98.9%,P=0.005).However,30-day readmission(31.6%vs 27.4%,P=0.64),LT complications(hepatic artery thrombosis,biliary complications,rejection of liver graft,cardiomyopathy),1-year patient survival(96.9%vs 97.8%,P=0.77),overall liver graft survival,and overall patient survival were similar between t

关键词： Liver transplantation Alprostadil Protective agents Transplant Prostaglandin E1

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Safety and outcomes of hip and knee replacement surgery in liver transplant recipients

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World Journal of Orthopedics 2023年第11期14卷 784-790页

作者： Mohamed Ahmed Abdelrhman Abumoawad Fouad Jaber Hebatullah Elsafy Saqr Alsakarneh Laith Al Momani alisa likhitsup John H Helzberg Department of Internal Medicine University of Missouri Kansas CityKansas CityMO 64108United States Department of Vascular Medicine Boston UniversityBostonMA 02215United States Department of Pathology Kansas UniversityKansas CityMO 66160United States Department of Gastroenterology University of Missouri Kansas CityKansas CityMO 64110United States Department of Gastroenterology and Hepatology University of MichiganAnn ArborMI 48109United States

BACKGROUND Liver transplant(LT)is becoming increasingly common with improved life *** replacement is usually a safe procedure;however,its safety in LT recipients remains *** To evaluate the mortality,outcome,and 90-d readmission rate in LT patients undergoing hip and knee replacement *** Patients with history of LT who underwent hip and knee replacement surgery between 2016 and 2019 were identified using the National Readmission *** A total of 5046119 hip and knee replacement surgeries were identified.3219 patients had prior *** age of patients with no history of LT was 67.51[95%confidence interval(CI):67.44-67.58],while it was 64.05(95%CI:63.55-64.54)in patients with *** with history of LT were more likely to have prolonged length of hospital stay(17.1%vs 8.4%,P<0.001).The mortality rate for patients with no history of LT was 0.22%,while it was 0.24%for patients with LT(P=0.792).Patients with history of LT were more likely to have re-admissions within 90 d of initial hospitalization:11.4%as compared to 6.2%in patients without history of LT(P<0.001).The mortality rate between both groups during readmission was not statistically different(1.9%vs 2%,P=0.871)*** Hip and knee replacements in patients with history of LT are not associated with increased mortality;increased readmissions were more frequent in this cohort of *** kidney disease and congestive heart failure appear to predict higher risk of readmission.

关键词： Liver transplant Hip replacement surgery Knee replacement surgery

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Solar hydrogen production from electrochemical ammonia splitting powered by a single perovskite solar cell

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Journal of Energy Chemistry 2024年第5期92卷 292-295页

作者： Anna MBeiler Wenhui Li alisa Denisiuk Emilio Palomares Antoni Llobet Institute of Chemical Research of Catalonia(ICIQ).Barcelona Institute of Science and Technology(BIST) 43007 TarragonaSpain Catalan Institution for Research and Advanced Studies(ICREA) 08010 BarcelonaSpain Departament de Química Universitat Autònoma de BarcelonaCerdanyola del Vallès08193 BarcelonaSpain

For carbon-free electrochemical fuel formation,the electrochemical cell must be powered by renewable *** solar-powered H_(2) fuel from water typically requires multiple photovoltaic cells and/or junctions to drive the water splitting *** of the lower thermodynamic requirements to oxidize ammonia compared to water,solar cells with smaller open circuit voltages can provide the required potential for ammonia *** this work,a single perovskite solar cell with an open-circuit potential of 1.08 V is coupled to a 2-electrode electrochemical cell employing hybrid electroanodes functionalized with Ru-based molecular *** device is active for more than 30 min,producing N_(2) and H_(2) in a 1:2.9 ratio with 89%faradaic efficiency with no external applied *** work illustrates that hydrogen production from ammonia can be driven by conventional semiconductors.

关键词： Ammonia oxidation Redox catalysis Perovskites Solarfuels Transitionmetal complexes

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Interfacial Electronic Modulation of Dual-Monodispersed Pt–Ni_(3)S_(2) as Efficacious Bi-Functional Electrocatalysts for Concurrent H_(2) Evolution and Methanol Selective Oxidation

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Nano-Micro Letters 2024年第4期16卷 415-431页

作者： Qianqian Zhao Bin Zhao Xin Long Renfei Feng Mohsen Shakouri alisa Paterson Qunfeng Xiao Yu Zhang Xian‑Zhu Fu Jing‑Li Luo Shenzhen Key Laboratory of Energy Electrocatalytic Materials Shenzhen Key Laboratory of Polymer Science and TechnologyGuangdong Research Center for Interfacial Engineering of Functional MaterialsCollege of Materials Science and EngineeringShenzhen UniversityShenzhen 518060People’s Republic of China Canadian Light Source Inc. SaskatoonSK S7N 0X4Canada Instrumental Analysis Center of Shenzhen University(Lihu Campus) Shenzhen UniversityShenzhen 518055People’s Republic of China

Constructing the efficacious and applicable bifunctional electrocatalysts and establishing out the mechanisms of organic electro-oxidation by replacing anodic oxygen evolution reaction(OER) are critical to the development of electrochemicallydriven technologies for efficient hydrogen production and avoid CO_(2) emission. Herein, the hetero-nanocrystals between monodispersed Pt(~ 2 nm) and Ni_(3)S_(2)(~ 9.6 nm) are constructed as active electrocatalysts through interfacial electronic modulation, which exhibit superior bi-functional activities for methanol selective oxidation and H_(2) generation. The experimental and theoretical studies reveal that the asymmetrical charge distribution at Pt–Ni_(3)S_(2) could be modulated by the electronic interaction at the interface of dual-monodispersed heterojunctions, which thus promote the adsorption/desorption of the chemical intermediates at the interface. As a result, the selective conversion from CH_(3)OH to formate is accomplished at very low potentials(1.45 V) to attain 100 m A cm^(-2) with high electronic utilization rate(~ 98%) and without CO_(2) emission. Meanwhile, the Pt–Ni_(3)S_(2) can simultaneously exhibit a broad potential window with outstanding stability and large current densities for hydrogen evolution reaction(HER) at the cathode. Further, the excellent bi-functional performance is also indicated in the coupled methanol oxidation reaction(MOR)//HER reactor by only requiring a cell voltage of 1.60 V to achieve a current density of 50 m A cm^(-2) with good reusability.

关键词： Dual-monodispersed heterostructure Electronic interactive modulation Reaction mechanism Methanol oxidation reaction Hydrogen generation

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Study of the DNA Extraction from the Nail by Spin Column-based Nucleic Acid Purification

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Journal of Forensic Science and Medicine 2024年第3期10卷 191-195页

作者： Kanchana Sujirachato Piya Wongyanin Pilaiwan Ramadjai alisa Ladsuk Kingkan Pokkasap Wisarn Worasuwannarak Department of Medical Technology Faculty of Science and TechnologyBansomdejchaopraya Rajabhat UniversityBangkokThailand Department of Pathology Faculty of Medicine Ramathibodi HospitalMahidol UniversityBangkokThailand

Background:Nails are one of the objects that are more durable than other witness *** study was interested in whether the Spin column-based nucleic acid purification technique could extract DNA from nails to give satisfactory *** and Objectives:This study aimed to evaluate the yield and quality of DNA extracted from the *** and Methods:Nail samples from 15 males and 15 females over 18 were extracted using GeneAll®Exgene™Cell SV Mini *** DNA concentration and purity were measured using a NanoDrop Spectrophotometer,and the quality of DNAwas assessed by polymerase chain reaction(PCR)using primers specific for human growth hormone(HGH).Results:The average yield of DNA was 0.816µg(0.141–2.706µg)obtained from the average nail weight of 30.2 mg(22.2–40.0 mg).The average DNA concentration was 27.2 ng/µL(4.7–90.2 ng/µL),corresponding to 30µL in *** all DNA samples(96.7%)had high purity(A260/A280≥1.80)and gave a band of PCR product of the HGH gene on agarose gel ***:Spin column-based nucleic acid purification is recommended for nail DNA extraction due to its simplicity and high quality.

关键词： DNA extraction nail DNA NanoDrop polymerase chain reaction spin column

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The Impact of Health Information Technology on Hospital Performance: A Systematic Integrative Literature Review

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Health 2024年第4期16卷 257-279页

作者： alisa Westerhof Cokky Hilhorst Willem Jan Bos Accounting Auditing & Control Nyenrode Business University Breukelen Netherlands St. Antonius Ziekenhuis Utrecht Netherlands Department of Internal Medicine Nephrology Leiden University Medical Center Leiden Netherlands

Objective: To review, categorise, and synthesise findings from literature on health information technology (HIT) functionalities, HIT use, and the impact of HIT on hospital performance. Materials and Methods: We conducted a systematic integrative literature review based on a compre-hensive database search. To organise, categorise and synthesise the ex-isting literature, we adopted the affordance actualization theory. To align the literature with our research framework, we used four categories: 1) the functionalities of HIT and how these functionalities are measured;2) use and immediate outcomes of HIT functionalities;3) different perfor-mance indicators and how HIT functionalities affect them;and 4) what hospital characteristics influence the outcome of hospital performance. Results: Fifty-two studies were included. We identified four types of HIT. Only ten studies (19.2%) define the use of HIT by explicitly meas-uring the use rate of HIT. We identified five dimensions of hospital per-formance indicators. Every dimension showed mixed results;however, in general, HIT has a positive impact on mortality and patient readmis-sions. We found several hospital characteristics that may affect the rela-tionship between HIT and hospital-level outcomes. Discussion: Further efforts should focus on embedded research on HIT functionalities, use and effects of HIT implementations with more performance indicators and adjusted for hospital characteristics. Conclusion: The proposed framework could help hospitals and researchers make decisions regard-ing the functionalities, use and effects of HIT implementation in hospi-tals. Given our research outcomes, we suggest future research opportuni-ties to improve understanding of how HIT affects hospital performance. .

关键词： Health Information Technology HIT Functionalities Hospital Performance Indicators

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Comparative Study of the Efficacy of Metal Removal from Contaminated Aqueous Solutions by Solid Bidentate Ligands&Liquid Plant Materials

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Journal of Environmental Science and Engineering(A) 2024年第2期13卷 45-49页

作者： Lovell Agwaramgbo Talajai Sardin Christopher alisa Chemistry Department Dillard UniversityNew OrleansLA 70122USA Biology Department Dillard UniversityNew OrleansLA 70122USA Chemistry Department Federal University of Technology OwerriPMB 1526OwerriNigeria

Heavy metal contaminated water sources pose serious health risks for humans,animals,and *** to and ingestion of heavy metals have been associated to liver,kidney,and brain ***:The aim of this research is to comparatively examine the metal removal efficacy of three solid bidentate chemicals and four plant *** Design&Methods:Standard solutions of zinc(II)and lead(II)ions with concentrations of 1,000 ppm were respectively treated with OA(Oxalic Acid),dibasic bidentate ligands(sodium hydrogen phosphate and sodium carbonate).Then,the solutions were placed on a shaker for 15 h,centrifuged,and the supernatant was analyzed using ICP-AES(Inductively Coupled Plasma-Atomic Emission Spectrometry).Results:All the solid bidentate adsorbents were very effective in removing zinc and lead(>90%).However,more lead than zinc was removed across all adsorbents except for lemon where equal percent of zinc and lead(49%)were *** and Na2HPO4 removed about equal amount of lead(>99%).The plant materials(SP(Spinach),bell pepper and GBP(Green Bell Pepper)),respectively and preferentially removed more lead(98.9%,98.3%,81.5%)than zinc(91.7%,46%,46%).Conclusion:Although plant materials have gained attraction for the remediation of heavy metal,however,some bidentate chemical ligands such as OA,sodium carbonate and sodium hydrogen phosphates are even more effective in removing these metals from contaminated ***,heavier metals are preferentially removed than lighter metals.

关键词： Organic acids OA remediation chelation ligands heavy metal contamination

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Security and Privacy Challenges in SDN-Enabled IoT Systems: Causes, Proposed Solutions,and Future Directions

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Computers, Materials & Continua 2024年第8期80卷 2511-2533页

作者： Ahmad Rahdari Ahmad Jalili Mehdi Esnaashari Mehdi Gheisari alisa A.Vorobeva Zhaoxi Fang Panjun Sun Viktoriia M.Korzhuk Ilya Popov Zongda Wu Hamid Tahaei Institute of Artificial Intelligence Shaoxing UniversityShaoxing312000China Department of Computer Engineering Gonbad Kavous UniversityGonbad-e Kavus49717-99151Iran Faculty of Computer Engineering K.N.Toosi University of TechnologyTehran196976-4499Iran Department of Computer Science and Engineering Saveetha School of EngineeringSaveetha Institute of Medical and Technical SciencesChennai602105India Secure Information Technologies Department National Research University ITMOSt.Petersburg197101Russia School of Electrical and Computer Engineering Shiraz UniversityShiraz71946–84334Iran Department of Computer Science and Engineering Islamic Azad UniversityDamavand***Iran Department of R&D Shenzhen BKD Co.Ltd.Shenzhen518000China

Software-Defined Networking(SDN)represents a significant paradigm shift in network architecture,separating network logic from the underlying forwarding devices to enhance flexibility and centralize ***-rently,the Internet of Things(IoT)connects numerous devices to the Internet,enabling autonomous interactions with minimal human ***,implementing and managing an SDN-IoT system is inherently complex,particularly for those with limited resources,as the dynamic and distributed nature of IoT infrastructures creates security and privacy challenges during SDN *** findings of this study underscore the primary security and privacy challenges across application,control,and data planes.A comprehensive review evaluates the root causes of these challenges and the defense techniques employed in prior works to establish sufficient secrecy and privacy *** investigations have explored cutting-edge methods,such as leveraging blockchain for transaction recording to enhance security and privacy,along with applying machine learning and deep learning approaches to identify and mitigate the impacts of Denial of Service(DoS)and Distributed DoS(DDoS)***,the analysis indicates that encryption and hashing techniques are prevalent in the data plane,whereas access control and certificate authorization are prominently considered in the control plane,and authentication is commonly employed within the application ***,this paper outlines future directions,offering insights into potential strategies and technological advancements aimed at fostering a more secure and privacy-conscious SDN-based IoT ecosystem.

关键词： Security privacy-preserving software-defined network internet of things

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老挝万象地区血红扇头蜱热带支（tropical lineage of Rhipicephalus sanguineus，Rhipicephalus linnaei）携带部分病原体调查

老挝万象地区血红扇头蜱热带支（tropical lineage of Rhipicepha...

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作者： BOUBPHAVANH alisa（亚利查）东北林业大学

学位级别：硕士

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Employment and development levels in rural areas of the Russian Federation

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Regional Sustainability 2024年第3期5卷 124-134页

作者： Guzel SALIMOVA Gulnara NIGMATULLINA Gamir HABIROV alisa ABLEEVA Rasul GUSMANOV Department of Finance Analysis and Accounting TechnologiesBashkir State Agrarian UniversityUfa450001the Russian Federation Department of Economics and Management Bashkir State Agrarian UniversityUfa450001the Russian Federation

The development of agro-industrial complex is important for ensuring national food security and national *** development of rural areas is subject to the development of agriculture and local infrastructure,as well as the availability of various *** study selected 15 indicators in 2021 to analyze the employment and development levels in rural areas of 71 regions of the Russian Federation using the analytical grouping *** results indicated that 20 regions(Group 1)had the highest percentage of rural population(33.10%).The percentage of population engaged in agriculture had the highest value(12.40%)in 31 regions(Group 2).Moreover,20 regions(Group 3)had the highest investments in fixed assets at the expense of municipal budget(11.80 USD/person).Increasing the investments in fixed assets carried out from the budget of the municipality can improve the employment level in rural ***,we used cluster analysis to divide 14 regions of the Volga Federal District in the Russian Federation into 3 *** 1 covered Kirov Region and Republic of Mari El;Cluster 2 included Ulyanovsk Region,Saratov Region,Nizhny Novgorod Region,Perm Territory,Orenburg Region,Chuvash Region,and Republic of Mordovia;and Cluster 3 contained Republic of Tatarstan,Samara Region,Udmurtian Republic,Penza Region,and Republic of *** indicated that the 2 regions of Cluster 1 need to increase the availability of resources and natural gas and improve the investment attractiveness of rural *** 7 regions of Cluster 2 needed to develop infrastructure,public services,and agricultural *** found the highest employment level in rural areas,the largest investments in fixed assets at the expense of municipal budget,the largest residential building area per 10,000 persons,and the largest individual residential building area in the 5 regions of Cluster *** study makes it possible to draw up a comprehensive regional development program and proves the

关键词： Rural areas Employment level Labor productivity Investments in fixed assets Sustainable Development Goal(SDG) Russian Federation

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