Safety and outcomes of hip and knee replacement surgery in liver transplant recipients

作     者：Mohamed Ahmed Abdelrhman Abumoawad Fouad Jaber Hebatullah Elsafy Saqr Alsakarneh Laith Al Momani Alisa Likhitsup John H Helzberg 

作者机构：Department of Internal MedicineUniversity of Missouri Kansas CityKansas CityMO 64108United States Department of Vascular MedicineBoston UniversityBostonMA 02215United States Department of PathologyKansas UniversityKansas CityMO 66160United States Department of GastroenterologyUniversity of Missouri Kansas CityKansas CityMO 64110United States Department of Gastroenterology and HepatologyUniversity of MichiganAnn ArborMI 48109United States 

出 版 物：《World Journal of Orthopedics》 (世界骨科杂志（英文版）)

年 卷 期：2023年第14卷第11期

页      面：784-790页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：Liver transplant Hip replacement surgery Knee replacement surgery 

摘      要：BACKGROUND Liver transplant(LT)is becoming increasingly common with improved life *** replacement is usually a safe procedure;however,its safety in LT recipients remains *** To evaluate the mortality,outcome,and 90-d readmission rate in LT patients undergoing hip and knee replacement *** Patients with history of LT who underwent hip and knee replacement surgery between 2016 and 2019 were identified using the National Readmission *** A total of 5046119 hip and knee replacement surgeries were identified.3219 patients had prior *** age of patients with no history of LT was 67.51[95%confidence interval(CI):67.44-67.58],while it was 64.05(95%CI:63.55-64.54)in patients with *** with history of LT were more likely to have prolonged length of hospital stay(17.1%vs 8.4%,P0.001).The mortality rate for patients with no history of LT was 0.22%,while it was 0.24%for patients with LT(P=0.792).Patients with history of LT were more likely to have re-admissions within 90 d of initial hospitalization:11.4%as compared to 6.2%in patients without history of LT(P0.001).The mortality rate between both groups during readmission was not statistically different(1.9%vs 2%,P=0.871)*** Hip and knee replacements in patients with history of LT are not associated with increased mortality;increased readmissions were more frequent in this cohort of *** kidney disease and congestive heart failure appear to predict higher risk of readmission.