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地学前缘 2009年第S1期16卷 62-62页

作者： alireza hajian Najaf Abad Branch Islamic Azad University

In this paper it has been presented the ELF Survey Meter and its application for investigation of presence of electric and magnetic fields strength in uranium conversion facilities,especially to investigate the effect of electric and magnetic sources on the operation of electrical controllers like PLC instruments, electrical drivers and actuators which are sensitive to presence of electrical and magnetic fields and also the effect of high voltage power lines

关键词： ELF survey meter uranium conversion facilities electrical and magnetic safety

Detection of Subsurface Cavities in a Power Plant Through Artificial Neural Network from Micro-Gravity Data

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地学前缘 2009年第S1期16卷 59-59页

作者： alireza hajian Caro Lucas Center of Excellence for Control and Intelligent Processing ECE DepartmentTehran University

Subsurface cavities are very susceptible subsurface locations for down-lifting of a dam *** order to detect the low-density zones of a power plant a micro-gravity survey was conducted in a site considered for construction of a power plant site in *** we gain the residual anomalies through bouger anomalies and then we design an Artificial Neural Network(ANN)which is trained by a set of training *** ANN was tested for both synthetic and real *** real data some suitable features are derivate from residual anomalies and applied to

关键词： artificial neural network power plant microgravity cavity

How to improve Iranians' vision health: on the national policy of preventing Iranians' blindness

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International Journal of Ophthalmology(English edition) 2019年第1期12卷 114-122页

作者： Behzad Damari alireza Mahdavi Maryam hajian Neuroscience Institute Tehran University of Medical Sciences Ministry of Health and Medical Education Minimally Invasive Surgery Research Center Iran University of Medical Sciences

AIM: To review vision health situation of Iranian community, analyze its determinants, and discuss the adopted improvement strategies by the Iran Ministry of Health and Medical Education(MOHME). METHODS: This was a rapid situation analysis with a qualitative approach in three parts of recognition, orientation and implementation. The data were gathered via review of upstream documents, national and international experiences, and experts and stakeholders' opinions. RESULTS: Eradicating trachoma, increasing human resources, increasing educational and research centers and promotion of ophthalmic technologies were important achievements in the field of vision health in Iran. Through these achievements, it seemed that the pattern of causes of blindness and low vision was similar to that of the developed countries. However, the review of Iranians' vision health indicators showed that a considerable percent of the blindness and low vision was avoidable through a national program demanding 3 types of interventions in social determinants of health(SDH), community education, and increasing the access to health care services by integrating the necessary services in primary health care system. CONCLUSION: Managing the issue requires attentions from a national committee for preventing blindness with participation of all stakeholders, implementing a national survey on vision health, preparation of the primary level health centers including employment and education of community health workers(Behvarzes), optometristsand general practitioners, fair distribution of specialized human resources and establishing at least one specialized center in each province for referring patients from the primary levels.

关键词： vision health policy document primary health care

Tuning the metal filling fraction in metal-insulator-metal ultra-broadband perfect absorbers to maximize the absorption bandwidth

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Photonics Research 2018年第3期6卷 168-176页

作者： AMIR GHOBADI HODJAT hajian alireza RAHIMI RASHED BAYRAM BUTUN EKMEL OZBAY NANOTAM-Nanotechnology Research Center Bilkent University Department of Electrical and Electronics Engineering Bilkent University Department of Physics Bilkent University UNAM-Institute of Materials Science and Nanotechnology Bilkent University

In this paper, we propose a methodology to maximize the absorption bandwidth of a metal-insulator-metal(MIM) based absorber. The proposed structure is made of a Cr-Al_2O_3-Cr multilayer design. At the initial step,the optimum MIM planar design is fabricated and optically characterized. The results show absorption above 0.9 from 400 nm to 850 nm. Afterward, the transfer matrix method is used to find the optimal condition for the perfect light absorption in an ultra-broadband frequency range. This modeling approach predicts that changing the filling fraction of the top Cr layer can extend light absorption toward longer wavelengths. We experimentally proved that the use of proper top Cr thickness and annealing temperature leads to a nearly perfect light absorption from 400 nm to 1150 nm, which is much broader than that of a planar design. Therefore, while keeping the overall process lithography-free, the absorption functionality of the design can be significantly improved. The results presented here can serve as a beacon for future performance-enhanced multilayer designs where a simple fabrication step can boost the overall device response without changing its overall thickness and fabrication simplicity.

关键词： Tuning the metal filling fraction perfect absorbers maximize the absorption bandwidth MIM

Study on the Interaction of Vitamin B12 with DNA by Spectroscopy and Electrochemical Methods

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Chinese Journal of Chemistry 2011年第7期29卷 1353-1358页

作者： hajian, Reza Zafari, Mitra Department of Chemistry Islamic Azad University Branch of Gachsaran Gachsaran 75818-63876 Iran

The Interaction between vitamin B12 （VBI2） and fish sperm DNA was investigated in physiological buffer （pH 7.4） using the methylene blue （MB） dye as a spectral probe by spetcrophotometery, viscosity measurements and cyclic voltammetry. The apparent binding constant of vitamin B12 with DNA was found to be 3.2 × 10^5 mol^-1·L. The voltammetric behavior of vitamin B12 has been investigated at glassy carbon electrode using cyclic voltammetry. Thermodynamic parameters including △H^0, △S^0 and △G^0 for the interaction between VB12 and DNA have determined as -2.3 × 10^4, 27.54 and -3.1 × 10^4j·mol^-l·K^-1 respectively. One indication of DNA binding mode with VBI2 was the change in viscosity when a small molecule associates with DNA. The diffusion coefficients of VB12 in the absence （D0）f and presence of DNA （D0）b was calculated as 5.04 × 10^-6 and 1.13 × 10^-6 cm^2·s^-1 respectively. The results indicated that vitamin B12 can bind to DNA and the major binding mode was intercalative binding.

关键词： vitamin B 12 fish sperm DNA interaction spectrophotometry cyclic voltammetry viscometry

Selective oxidation of alcohols with H2O2 catalyzed by zinc polyoxometalate immobilized on multi-wall carbon nanotubes modified with ionic liquid

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Chinese Chemical Letters 2017年第5期28卷 971-975页

作者： Robabeh hajian Zahra Alghour Department of Chemistry Yazd UniversityYazd 89195-741lran

In this work,acid functionalized multi-wall carbon nanotubes（MWCNTs） were modified with imidazolium-based ionic *** selective oxidation of various alcohols with hydrogen peroxide catalyzed by [PZnMo2W9O39]^5-,ZnPOM,supported on ionic liquids-modified with MWCNTs,MWCNTAPIB,is *** catalyst[ZnPOM@APIB-MWCNT],was characterized by X-ray diffraction,scanning electron microscopy（SEM） and FT-IR spectroscopic *** heterogeneous catalyst exhibited high stability and reusability in the oxidation reaction without loss of its catalytic performance.

关键词： Immobilized ionic liquid [PZnMo2W9O39]^5- Hydrogen peroxide Oxidation Alcohol Heterogeneous catalyst

Fabrication of an electrochemical sensor for determination of doxorubicin in human plasma and its interaction with DNA

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Journal of Pharmaceutical Analysis 2017年第1期7卷 27-33页

作者： Reza hajian Zahra Tayebi Nafiseh Shams Young Researchers and Elite Club Gachsaran Branch Islamic Azad University 75818-63876 Gachsaran Iran Department of Chemistry College of Science Gachsaran Branch Islamic Azad University 75818-63876 Gachsaran Iran Institute of Advanced Technology Universiti Putra Malaysia 43400 Serdang Selangor Malaysia

In this work, an electrochemical sensor was fabricated for determination of an anthracycline, doxorubicin(DOX) as a chemotherapy drug in plasma based on multi-walled carbon nanotubes modified platinum electrode(Pt/MWCNTs). DOX was effectively accumulated on the surface of modified electrode and generated a pair of redox peaks at around 0.522 and 0.647 V(vs. Ag/Ag Cl) in Britton Robinson(B-R) buffer(p H 4.0, 0.1 M). The electrochemical parameters including p H, type of buffer, accumulation time, amount of modifier and scan rate were optimized. Under the optimized conditions, there was a linear correlation between cathodic peak current and concentration of DOX in the range of 0.05–4.0 μg/m L with the detection limit of 0.002 μg/m L. The number of electron transfers(n) and electron transfer-coefficient(α) were estimated as 2.0 and 0.25, respectively. The constructed sensor displayed excellent precision, sensitivity, repeatability and selectivity in the determination of DOX in plasma. Moreover, cyclic voltammetry studies of DOX in the presence of DNA showed an intercalation mechanism with binding constant(K_b) of 1.12×10~5L/mol.

关键词： Doxorubicin MWCNTs Electrochemical sensor Human plasma Doxorubicin-DNA interaction

Electrochemical Study on the Interaction of Irinotecan with Calf Thymus Double Stranded DNA

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Chinese Journal of Chemistry 2012年第3期30卷 738-742页

作者： hajian, Reza Huat, Tan Guan Department of Chemistry Faculty of Science University of Malaya 50603 Kuala Lumpur Malaysia

Voltammetric behavior of Irinotecan （CPT-11） was studied in a phosphate buffer （0.002 mol.L^-1, pH 7.5） solution at the hanging mercury drop electrode （HMDE） using cyclic voltammetry （CV）. CPT-11 showed two irreversible cathodic peaks at - 1.01 V and - 1.09 V which involved two electrons and two protons in each reduction step. In addition, the interaction of Irinotecan with double-stranded calf thymus DNA （ds-DNA） was studied by CV at the HMDE employing an irreversible electrochemical equation. As a result of the reaction with ds-DNA, the reduc- tion peaks related to CPT-11 were shifted in a negative direction and the peak currents were decreased. The diffu- sion coefficients of CPT- 11 in the absence （Dr） and presence （Db） of ds-DNA were calculated as 2.8 ×10 5 cm2.s^- 1 and 1.6 × 10^-5 cm2·s^-1 respectively. The binding constant （K=1.0×10^4 L·mol^-1）, and binding site size （s=0.60） of CPT-11 interacting with ds-DNA were obtained simultaneously by non-linear fit analysis. The results demon strate that the main interaction mode of CPT-11 with ds-DNA is electrostatic.

关键词： Irinotecan ds-DNA cyclic voltammetry anticancer drugs interactions

Atlas of heating:Identifying regional climate-dependent heat demands in residential buildings of Iran

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Building Simulation 2021年第3期14卷 857-869页

作者： Pouria Orouji Ramin hajian Mojgan Moradi Saeed Mohaghegh Kamran Keynejad Mostafa Sefidgar Energy Department Asiawatt Engineering CompanyTehranIran Niroo Research Institute TehranIran Fouman Faculty of Engineering College of EngineeringUniversity of TehranGilanIran Pardis Islamic Azad University TehranIran

Due to different latitudes and variation of altitude in geographical areas in Iran,the climatic conditions of Iran are such that the variations of the heating degree-days(HDD)are in a broad range of 60 to 3000 for residential buildings in different climatic *** addition,in many cases,the building design and construction processes follow patterns which do not necessarily meet national energy requirements and *** on these two reasons,it is essential to identify the current status of energy consumption indicators in residential *** way,it gets more convenient to adopt new strategies to improve the current state of energy consumption of *** this study,heating energy consumption indices of residential buildings is *** the combination of the results of statistical data analysis,questionnaires,filled in for 500 buildings,and a reference building simulation in different climates of Iran,the heating atlas of residential buildings was *** to the results,the average heating energy index(HE1)of buildings in Iran can be less than 1 to more than 41.3(m^(3)(N.G)/(m^(2)-yr))depending on climatic conditions and building design and construction ***,in the coldest center of province,the average of this index is 26.3(m^(3)(N.G)/(m^(2)-yr))in the hottest one that is equal *** variations of the thermal base load(supply of hot water)varied from less than 13.12 to more than 378.84(m^(3)(N.G)/(person-yr)).In provincial capitals,the lowest thermal base load index(TBLI)of buildings is 24.78 and the highest is 226.49(m^(3)(N.G)/(person-yr)).In this paper,beside charts and tables,results of heating energy consumption indices are also presented in the form of graphical atlases,*** contour plots,to deliver a better picture of the whole country.

关键词： heating atlas reference building heating energy index thermal base load index residential building

DNA-binding studies of valrubicin as a chemotherapy drug using spectroscopy and electrochemical techniques

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Journal of Pharmaceutical Analysis 2017年第3期7卷 176-180页

作者： Reza hajian Parvin Hossaini Zahra Mehrayin Pei Meng Woi Nafiseh Shams Department of Chemistry College of Science Gachsaran Branch Islamic Azad University Institute of Advanced Technology Universiti Putra Malaysia Department of Chemistry Faculty of Science University of Malaya

In this study, the molecular interactions between valrubicin, an anticancer drug, and fish sperm DNA have been studied in phosphate buffer solution(pH 7.4) using UV–Vis spectrophotometry and cyclic voltammetry techniques. Valrubicin intercalated into double stranded DNA under a weak displacement reaction with methylene blue(MB) molecule in a competitive reaction. The binding constant(kb) of valrubicin-DNA was determined as 1.75×10~3L/mol by spectrophotometric titration. The value of non-electrostatic binding constant(k_t^0) was almost constant at different ionic strengths while the ratio of k_t^0/k_b increased from 4.51% to 23.77%.These results indicate that valrubicin binds to ds-DNA via electrostatic and intercalation *** parameters including ΔH^0, ΔS^0and ΔG^0for valrubicin-DNA interaction were determined as-25.21×10~3k J/mol, 1.55×10~2k J/mol K and-22.03 k J/mol, respectively. Cyclic voltammetry study shows a pair of redox peaks for valrubicin at 0.45 V and 0.36 V(vs. Ag/Ag Cl). The peak currents decreased and peak positions shifted to positive direction in the presence of DNA, showing intercalation mechanism due to the variation in formal potential.

关键词： Valrubicin-DNA interactions Spectroscopy Cyclic voltammetry