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Rotational Oscillation Effect on Flow Characteristics of a Circular Cylinder at Low Reynolds Number

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World Journal of Mechanics 2015年第10期5卷 195-209页

作者： alice rosa da silva Aristeu da Silveira-Neto Antonio Marcos Goncalves de Lima School of Civil Engineering Federal University of UberlandiaUberlandiaBrazil School of Mechanical Engineering Federal University of UberlandiaBrazil

Two dimensional numerical simulations of flow around a rotationally oscillating circular cylinder were performed at Re = 1000. A wide range of forcing frequencies, fr, and three values of oscillation amplitudes, A, are considered. Different vortex shedding modes are observed for a fixed A at several values of fr, as well as for a fixed fr at different values of A. The 2C mode of vortex shedding was obtained in the present study. It is important to point out that this mode has not been observed by other investigators for rotationally oscillating case. Also, it is verified that this mechanism has great influence on the drag coefficient for high frequency values. Furthermore, the lift and pressure coefficients and the power spectra density are also analyzed.

关键词： Rotationally Oscillating Cylinder Vortex Shedding Modes Drag Coefficient

Concerns about the application of resistance exercise with blood-flow restriction and thrombosis risk in hemodialysis patients

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Journal of Sport and Health Science 2024年第4期13卷 548-558,F0003页

作者： Hugo de Luca Correa Lysleine Alves Deus dahan da Cunha Nascimento Nicholas Rolnick Rodrigo Vanerson Passos Neves Andrea Lucena Reis Thais Branquinho de Araujo Carmen Tzanno-Martins Fernanda Silveira Tavares Luiz Sinesio silva Neto Claudio Avelino Rodrigues Santos Paolo Lucas Rodrigues-silva Fernando Honorato Souza Vitoria Marra da Motta Vilalva Mestrinho Rafael Lavarini dos Santos rosangela Vieira Andrade Jonato Prestes Thiago dos Santos rosa Post-graduate Program of Physical Education Catholic University of BrasıliaBrasılia 71966-700Brazil The Human Performance Mechanic Lehman CollegeNew YorkNY 10011USA Clinical Group Home Dialysis Center and RenalClass Sao Paulo 01239-040Brazil Department of Medicine Catholic University of BrasıliaBrasılia 71966-700Brazil Faculty of Medicine Federal University of TocantinsTocantins 77001-090Brazil Embrapa Genetic Resources and Biotechnology Brasılia 70770-917Brazil Graduate Program of Genomic Sciences and Biotechnology Brasılia 71966-700Brazil

Background:Hemodialysis(HD) per se is a risk factor for *** the growing body of evidence on blood-flow restriction(BFR) exercise in HD patients,identification of possible risk factors related to the prothrombotic agent D-dimer is required for the safety and feasibility of this training *** aim of the present study was to identify risk factors associated with higher D-dimer levels and to determine the acute effect of resistance exercise(RE) with BFR on this ***:Two hundred and six HD patients volunteered for this study(all with a glomerular filtration rate of 70 years old),and HD ***,RE+BFR significantly increases D-dimer after 4 *** with borderline baseline D-dimer levels(400-490 ng/mL) displayed increased risk of elevating D-dimer over the normal range(≥500 ng/mL).Conclusion:These results identified factors associated with a heightened prothrombotic state and may assist in the screening process for HD patients who wish to undergo RE+BFR.D-dimer and/or other fibrinolysis factors should be assessed at baseline and throughout the protocol as a precautionary measure to maximize safety during RE+BFR.

关键词： Blood-flow restriction Chronic kidney disease Coagulation Hemodialysis Vascular occlusion exercises

Response to Commentary by Dr. Matthew J. Clarkson on

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Journal of Sport and Health Science 2024年第5期13卷 670-671页

作者： Hugo de Luca Corrêa Lysleine Alves Deus dahan da Cunha Nascimento Nicholas Rolnick Rodrigo Vanerson Passos Neves Andrea Lucena Reis Thais Branquinho de Araújo Carmen Tzanno-Martins Fernanda Silveira Tavares Luiz Sinésio silva Neto Cláudio Avelino Rodrigues Santos Paolo Lucas Rodrigues-silva Fernando Honorato Souza Vitória Marra da Motta Vilalva Mestrinho Rafael Lavarini dos Santos rosangela Vieira Andrade Jonato Prestes Thiago dos Santos rosa Post-graduate Program of Physical Education Catholic University of BrasıliaBrasılia 71966-700Brazil The Human Performance Mechanic Lehman CollegeNew YorkNY 10011USA Clinical Group Home Dialysis Center and RenalClass Sao Paulo 01239-040Brazil Department of Medicine Catholic University of BrasıliaBrasılia 71966-700Brazil Faculty of Medicine Federal University of TocantinsTocantins 77001-090Brazil Embrapa Genetic Resources and Biotechnology Brasılia 70770-917Brazil g Graduate Program of Genomic Sciences and Biotechnology Brasılia 71966-700Brazil

Dear editor:We sincerely thank Matthew *** for his insightful commentary1 on our recent publication in the Journal of Sport and Health Science.2 Clarkson's pioneering work in the development and application of blood flow restriction (BFR) exercise protocols has undeniably laid the groundwork for subsequent investigations in this field,including our own.(3-6)His commentary not only highlights the relevance and timeliness of our study but also offers valuable perspectives on refining safety considerations for intradialytic BFR exercise among hemodialysis patients.

关键词： patients application flow

In Silico and in Vitro Analysis of Pyrazolone Derivatives against Zika Virus and Identification of Potential NS5 Methyltransferase Inhibitors by Molecular Docking

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Journal of Biosciences and Medicines 2024年第7期12卷 214-229页

作者： Luciene Soares silva Tiago Soares Barbosa Maria Leonisa Sanchez-Nuñez Aldenise Mont Serrat rosa da silva Vitor Won-Held Rabelo Leonardo dos Santos Corrêa Amorim Leonardo Alves Miceli Percilene Fazolin Vegi alice Bernardino Helena Carla Castro Izabel Christina Nunes de Palmer Paixão Science and Biotechnology Graduate Program Department of Cellular and Molecular Biology Institute of Biology Fluminense Federal University Niteri Brazil Science and Biotechnology Graduate Program Department of Cellular and Molecular Biology Institute of Biology Fluminense Federal University Niterói Brazil Laboratory of Antibiotics Biochemistry Teaching and Molecular Modeling Institute of Biology Fluminense Federal University Niterói Brazil Laboratory of Organic Chemistry at the Institute of Chemistry Institute of Biology Fluminense Federal University Niterói Brazil

Zika virus (ZIKV), a mosquito-borne flavivirus, has been associated with benign infections for decades. However, it has become a public health concern due to its association with severe fetal and neurological complications. Although many efforts have been made to control ZIKV infection, approved vaccines or antiviral drugs are still lacking. Consequently, the development of new effective anti-ZIKV agents is urgently needed. In this context, we investigated the antiviral potential of pyrazolone derivatives against ZIKV replication using in silico and in vitro methods. The four pyrazolone derivatives evaluated (1a, 1b, 1c, and 1d) inhibited over 50% of ZIKV replication with low cytotoxicity. Among them, compound 1b exhibited the most potent activity (EC50 = 4.3 μM) and the highest selectivity (SI = 342). Mechanism of action studies indicated that these compounds act at early stages of virus replication, and compound 1b can also directly inactivate ZIKV particles. Molecular docking studies suggested that these compounds can bind to and block the activity of ZIKV NS5 methyltransferase. Finally, pharmacokinetic and toxicological predictions have reinforced the safety and drug-like profiles of these derivatives. In conclusion, the pyrazolone scaffold proved to be valuable for anti-ZIKV drug development, and the derivatives studied deserve further investigation.

关键词： Zika Pyrazolone NS5 Methyltransferase Antivirals

Comparison of Surgical Techniques Used in Treating Acromioclavicular Dislocation in Patients Participating in Sports: A Systematic Review

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Open Journal of Orthopedics 2024年第1期14卷 41-52页

作者： Walter Hugo Brandão Nascimento Paulo Renan Matos Sucupira Cunha João Pedro Pimentel Abreu Lethycia Pereira rosa Kamilly Iêda silva Veigas Rodrigo Martins silva Caetano Orthopedic and Trauma Surgeon Brazilian Army Rio de Janeiro Brazil Orthopedic and Trauma Surgeon S&atildeo Luís Brazil Scholarship Holder National Council for Scientific and Technological Development (CNPq) S&atildeo Luís Brazil School of Medicine Federal University of Maranh&atildeo (UFMA) S&atildeo Luís Brazil Orthopedic and Trauma Surgeon Shoulder and Elbow Surgery Specialist University Hospital of the Federal University of Maranh&atildeo (HUUFMA/EBSERH) S&atildeo Luís Brazil

Introduction: The acromioclavicular joint is a superficial diarthrodial joint that surrounds the medial articular facet of the acromion and the distal portion of the clavicle. Due to its anatomy and biomechanics, it is highly susceptible to trauma and in young men who play contact sports, acromioclavicular dislocation is common. This article aimed to systematically review the literature and compare the surgical techniques used in the treatment of acromioclavicular dislocation in patients who practice sports. Methods: This systematic review was conducted according to the International Preferred Reporting Items for Systematic Review and Meta-Analyses guidelines. Eligible studies for this systematic review included articles in English or Spanish published between 2013 and 2023, which mention the occurrence of acromioclavicular dislocation during sports practices. Additionally, only studies that addressed the surgical treatment of acromion-clavicular dislocation and contained original data on the topic were included. Results: We found 144 eligible studies after searching the LILACS and PubMed databases. Based on the inclusion and exclusion criteria and the reviewers’ consensus, we selected four studies for the systematic review. 133 patients with AC joint displacement were evaluated. Mean Age: approximately 31.90 years. 81.92 of these injuries occurred during sports practice. Surgical Procedures Used: titanium plates fixation (49 patients), arthroscopy (24), single tunnel technique (30) and coracoid sling technique (30). The results of the visual analog scale and Constant-Murley scores varied between the techniques used. Twenty-two complications after surgical treatment were identified. Conclusion: A significant variability of operative techniques can be used in the surgical approach of acromioclavicular dislocation, such as arthroscopy, single tunnel, coracoid sling and titanium plates. Although it presented excellent functional results compared to the other three tech

关键词： Acromioclavicular Joint Shoulder Dislocation Surgical Procedure Postoperative Complications Postoperative Care

Dehydrated Natural Feed for Cats: Influence on Apparent Digestibility Coefficient, Feces Scores, and Serum Immune, Antioxidant, and Metabolic Biomarkers

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Food and Nutrition Sciences 2024年第7期15卷 594-611页

作者： Bruno Giorgio de Oliveira Cécere Guilherme Luiz Deolindo Bianca F. Bissacotti Priscila Marquezin Copetti Maria rosa Chitolina Schetinger Bruna Klein Matheus Delamea Baldissera Thiago Pereira Ribeiro Walter Hugo Cuelho Suarez daniel Pigatto Monteiro Aleksandro Schafer da silva Graduate Multicenter Program in Biochemistry and Molecular Biology University of the State of Santa Catarina Lages Brazil Department of Biochemistry and Molecular Biology Universidade Federal de Santa Maria (UFSM) Santa Maria Brazil Department of Animal Science Universidade Federal de Santa Maria (UFSM) Chapec Brazil Department of Health Science Universidade Franciscana (UFN) Santa Maria Brazil Department of Animal Nutrition Tectron-Tecnologia e Inovao Toledo Brazil

The present study aimed to determine whether natural dehydrated feed (DNF) can replace dry extruded feed while preserving the required daily intake, nutrient digestibility and benefits for immunity and antioxidant response in cats. The animals were divided into two groups of seven animals each. One group received DNF, and the other consumed commercial extruded dry feed (DCF). The experiment lasted 45 days and we measured daily consumption and collected blood and feces samples. The animals in the DNF group showed greater digestibility of fiber and mineral matter than DCF. Cats in the DNF group had a higher volume of feces. DNF cats had lower leukocyte and granulocyte counts and cholesterol levels. Serum enzymatic antioxidant responses and non-enzymatic were higher in DNF cats. Cats in the DNF group showed lower serum acute phase proteins in addition to a tendency toward a higher concentration of transferrin than in the DCF group. Fecal Escherichia coli and total coliform counts of cats fed DNF were higher than DCF. We conclude that the daily consumption of cats is adequate. This feed had greater digestibility of fiber and mineral matter, in addition to an improvement in antioxidant and immunological responses.

关键词： Alternative Feed Antioxidant Companion Animals Health

Litter removal impacts on soil biodiversity and eucalypt plantation development in the seasonal tropics

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Journal of Forestry Research 2023年第3期34卷 735-748页

作者： Jonas Inkotte Barbara Bomfim Sarah Camelo da silva Marco Bruno Xavier Valadão Márcio Gonçalves da rosa Roberta Batista Viana Alcides Gatto Reginaldo SPereira Department of Forestry Engineering University of BrasiliaBrasíliaDistrito FederalBrazil Climate and Ecosystem Sciences Division Lawrence Berkeley National LaboratoryBerkeleyCA 94720USA SESI/SENAI Social Service Industry Santa Catarina StateChapecóBrazil

The little layer of tree plantations provides primary nutrients for uptake,buff ers changes in soil moisture,and provides habitat and substrate to soil epigeic ***,this layer in eucalypt plantations is often removed to reduce fuel load during the fi re season in the Brazilian savanna(Cerrado).Therefore,it is necessary to quantify the eff ects of changes in litter dynamics on the function of these plantations,on key nutrient cycling processes and on epigeic fauna diversity and *** two adjacent stands(one juvenile and one mature),the consequences of two years of litter removal were quantifi ed as monthly litterfall,leaf and fi ne wood litter decomposition,epigeic fauna abundance and diversity,soil biogeochemical variables,and tree diameter and basal area *** litterfall rates in juvenile and mature stands did not change with litter removal over the study *** litterfall ranged from 4.1 to 4.9 Mg ha^(−1)a^(−1)in litter removal plots and from 3.9 to 4.8 Mg ha^(−1)a^(−1)in control *** wood litter decomposition was slower in litter removal plots compared to controls,while leaf decomposition rates were similar in *** years of litter removal in the juvenile stand did not aff ect topsoil biogeochemical parameters but decreased available phosphorus at 20–40 cm depth relative to *** the mature stand,total cation exchange capacity(0–20 cm)was higher in controls(6.4 cmol c dm^(−3))relative to litter removal plots(6.3 cmol c dm^(−3)),while soil moisture(0–40 cm depth)was lower in litter removal(25.45 m 3 m^(−3))compared to control plots(26 m^(3)m^(−3))in the dry season.A non-metric multidimensional scaling ordination revealed an increased homogeneity in epigeic fauna where litter was ***,decomposition,diameter increment,four soil physical parameters and fourteen chemical parameters at 0–20 and 20–40 cm depth explained the diff erences in soil epigeic fauna composition between litter removal and control p

关键词： Cerrado Nutrient cycling Soil ecology Soil epigeic fauna Plantation management

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国际护理知识网络建设的调查研究

International Journal of Nursing Sciences 2024年第3期11卷 374-380,I0004,I0005页

作者： Margareth Santos Zanchetta Suzanne Fredericks Kateryna Metersky Geraldine Martorella Pammla Petrucka Laurie Clune Kelly Graziani Giacchero Vedana Cristina rosa Soares Lavareda Baixinho Cristianne Maria Famer Rocha Sara Campagna Sally Zhang He Márcia Teles de Oliveira Gouveia Marcelo Medeiros Denize Bouttelet Munari daniel Gonzalo Eslava Albarracin Carlos Aguilera-Serrano Walterlania silva Santos Toronto Metropolitan University TorontoCanada Florida State University TallahasseeUSA University of Saskatchewan ReginaCanada University of Regina ReginaCanada State of Sao Paulo University Ribeirao PretoBrazil Lisbon Superior School of Nursing LisbonPortugal Federal University of Rio Grande do Sul Porto AlegreBrazil University of Turin TurinItaly Scarborough Health Network ScarboroughCanada Federal University of Piauí TeresinaBrazil Federal University of Goias GoianiaBrazil Fundacion Universitaria Cafam BogotaColombia University of Malaga MalagaSpain University of Brasília Ceil^andiaBrazil

本文报告了为创建护理知识网络(Nursing Knowledge Network,NKN)对不同国家护理院校进行环境扫描调查所收集到的信息。采用在线方式(2021年2-10月)进行环境扫描,探索研究领域的确定、现有资源、预期收益、教学研究创新、知识传播障碍及... 详细信息

本文报告了为创建护理知识网络(Nursing Knowledge Network,NKN)对不同国家护理院校进行环境扫描调查所收集到的信息。采用在线方式(2021年2-10月)进行环境扫描,探索研究领域的确定、现有资源、预期收益、教学研究创新、知识传播障碍及网络的预期贡献。目标信息提供者包括来自13个国家63所大学的200名护理教师。要求每所大学有1名参与者回答问卷。共有42所大学(约70%)回复,包括巴西21所,加拿大4所,葡萄牙和西班牙各3所,哥伦比亚、墨西哥、秘鲁和美国各2所,智利、意大利和巴拉圭各1所。其分享了相关信息和见解:通过护理高等教育机构之间的协作和交流,全球可以加强共同创新和研究合作能力;较少被研究的领域是知识网络生成证据、为当地科学实践提供信息的潜在重点。这些信息将为进一步了解护理发展,以及地方、区域和全球护理证据应用和传播相关的政府政策与计划制订提供参考。

关键词：信息网络创新扩散国际教育交流知识管理护理教育护理教师实践护理院校跨文化护理

香椿的树木年轮宽度与超年生殖行为的相互关系:对树轮学研究的警示

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Journal of Plant Ecology 2024年第1期17卷 165-171页

作者： Monique silva Costa Thaís Jorge de Vasconcellos Claudio Sergio Lisi Arno Fritz Neves Brandes Mario Tomazello-Filho Cátia Henriques Callado Instituto de Aplicação Fernando Rodrigues da Silveira Universidade do Estado do Rio de JaneiroRua Barão de Itapagipe96.Rio Comprido 20261-005Rio de JaneiroBrazil Laboratório de Anatomia Vegetal Universidade do Estado do Rio de JaneiroRua São Francisco Xavier524Maracanã20550-013Rio de JaneiroBrazil Departamento de Biologia Universidade Federal de SergipeAv.Marechal Rondon s/n-Rosa Elze.São Cristóvão 49100-000SergipeBrazil Departamento de Biologia Geral Universidade Federal FluminenseRua Prof.Marcos Waldemar de Freitas ReisS/N.Gragoatá24210-201Rio de JaneiroBrazil Escola Superior de Agricultura Luiz de Queiroz Universidade de São PauloAv.Pádua Dias11.Piracicaba 13418-900São PauloBrazil

资源分配到生殖过程涉及到生态和进化因素,可能会减少植物的营养生长。这种相互关系在自然界中不容易观察到,因为有许多参数可以限制生殖结构的产生或生物量的增加。我们将香椿(Cedrela odorata L.,楝科)在里约热内卢州大西洋森林中的... 详细信息

资源分配到生殖过程涉及到生态和进化因素,可能会减少植物的营养生长。这种相互关系在自然界中不容易观察到,因为有许多参数可以限制生殖结构的产生或生物量的增加。我们将香椿(Cedrela odorata L.,楝科)在里约热内卢州大西洋森林中的树木年轮宽度与超年生殖行为相关联。总体而言,生殖结构的发育发生在湿润的年份,在生长季初期没有出现水分亏缺。然而,在这些年份,树木年轮宽度较小。这些结果可能与树木年轮宽度与当地气候之间缺乏相关性有关。因此,我们强调在径向生长研究中纳入生殖数据的重要性,以扩大对热带森林生长变异性的理解。

关键词：植物生长策略树木年轮学树木生态学生殖权衡