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Frontiers of Chemical Science and Engineering 2024年第2期18卷 69-81页

作者： Zulfiqar ali Jiliang Ma Dongnv Jin Rui Cui Runcang Sun Liaoning Key Lab of Lignocellulose Chemistry and Biomaterials Liaoning Collaborative Innovation Center for Lignocellulosic BiorefineryCollege of Light Industry and Chemical EngineeringDalian Polytechnic UniversityDalian 116034China

The use of functional materials such as carbon-bismuth oxyhalides in integrated photorefineries for the clean production of fine chemicals requires restructuring.A facile biomass-assisted solvothermal fabrication of carbon/bismuth oxychloride nanocomposites(C/BiOCl)was achieved at various *** with BiOCl and C/BiOCl-120,C/BiOCl-180 exhibited higher crystallinity,wider visible light absorption,and a faster migration/separation rate of photoinduced *** the selective C–C bond cleavage of biomass-based feedstocks photocatalyzed by C/BiOCl-180,the xylose conversion and lactic acid yield were 100%and 92.5%,respectively.C/BiOCl-180 efficiently converted different biomass-based monosaccharides to lactic acid,and the efficiency of pentoses was higher than that of ***,lactic acid synthesis was favored by all active radicals including superoxide ion(·O_(2)^(−)),holes(h^(+)),hydroxyl radical(·OH),and singlet oxygen(^(1)O_(2)),with·O_(2)^(−)playing a key *** fabricated photocatalyst was stable,economical,and *** use of biomass-derived monosaccharides for the clean production of lactic acid via the C/BiOCl-180 photocatalyst has opened new research horizons for the investigation and application of C–C bond cleavage in biomass-based feedstocks.

关键词： carbon-carbon bond cleavage biomass reforming C/BiOCl lactic acid photocatalysis

Defining failure of endoluminal biliary drainage in the era of endoscopic ultrasound and lumen apposing metal stents

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World Journal of Gastroenterology 2024年第29期30卷 3534-3537页

作者： Faisal S ali Sushovan Guha Department of Gastroenterology Hepatologyand NutritionUniversity of Texas Health Science Center at HoustonHustonTX 77054United States Department of Clinical Sciences Tilman J.Fertitta Family College of MedicineUniversity of HoustonHoustonTX 77204United States

The role of endoscopy in pathologies of the bile duct and gallbladder has seen notable advancements over the past two *** advancements in stent technology,such as the development of lumen-apposing metal stents,and adoption of endoscopic ultrasound and electrosurgical principles in therapeutic endoscopy,what was once considered endoscopic failure has transformed into failure of an approach that could be salvaged by a second-or third-line endoscopic *** of these advancements in routine patient care will require formal training and multidisciplinary acceptance of established techniques and collaboration for advancement of experimental techniques to generate robust evidence that can be utilized to serve patients to the best of our ability.

关键词： Endoscopic ultrasound Guided biliary drainage Gallbladder Biliary obstruction Lumen-apposing metal stent

Hydrodynamic Assessment of A New Nature-Based Armour Unit on Rubble Mound Breakwater for Coastal Protection

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China Ocean Engineering 2024年第3期38卷 439-452页

作者： Ehsan SAFA alireza MOJTAHEDI Abdolmajid MOHAMMADIAN Mohamad ali Lotfollahi YAGHIN Department of Water Resources Engineering Faculty of Civil EngineeringUniversity of TabrizTabriz ***Iran Faculty of Civil Engineering University of OttawaOttawa K1H 8M5Canada

This research proposes a novel nature-based design of a new concrete armour unit for the cover layer of a rubblemoundbreakwater. Armour units are versatile with respect to shape, orientation, surface condition details, and ***, a detailed analysis is required to investigate the exact state of their hydraulic interactions and structuralresponses. In this regard, the performance results of several traditional armour units, including the Antifer cube,Tetrapod, X-block and natural stone, are considered for the first step of this study. Then, the related observed resultsare compared with those obtained for a newly designed (artificial coral) armour unit. The research methodology utilizesthe common wave flume test procedure. Furthermore, several verified numerical models in OpenFOAM code areused to gain the extra required data. The proposed armour is configured to provide an effective shore protection as anenvironmental-friendly coastal structure. Thus it is designed with a main trunk including deep grooves to imitate thetypical geometry of a coral type configuration, so as to attain desirable performance. The observed results and ananalytic hierarchy process (AHP) concept are used to compare the hydraulic performance of the studied traditionaland newly proposed (artificial coral) armour units. The results indicate that the artificial coral armour unit demonstratesacceptable performance. The widely used traditional armour units might be replaced by newer designs for betterwave energy dissipation, and more importantly, for fewer adverse effects on the marine environment.

关键词： rubble mound breakwater hydraulic interaction armour unit analytic hierarchy process numerical model

Single nucleotide polymorphism within chromosome 8q24 is associated with prostate cancer development in Saudi Arabia

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Asian Journal of Urology 2024年第1期11卷 26-32页

作者： Awad Elsid Osman Sahar alharbi Atif ali Ahmed Asim ali Elbagir Pathology and Clinical Laboratory Management Department(PCLM) King Fahad Medical CityRiyadhSaudi Arabia Department of Pathology and Laboratory Medicine University of Missouri at Children's Mercy HospitalKansas CityMOUSA

Objective: Genome-wide association studies have demonstrated that single nucleotide polymorphisms (SNPs) are important risk factors for the development of prostate cancer (PCa). Preliminary studies have suggested that the incidence of PCa in Saudi males is low but is probably familial or genetically ***: To identify any possible association of SNP with PCa development in Saudi patients, we investigated a group of SNPs in Saudi PCa patients (n=85) and compared the outcomes to healthy normal controls (n=115) and nodular hyperplasia patients (n=120). DNA was extracted from paraffin-embedded formalin fixed tissue or whole blood from both patients’ groups and healthy control group. A total of thirteen SNPs were genotyped using TaqMan® minor groove binder polymerase chain reaction ***: The rs16901979A, s629242T and rs1447295A alleles were found at significantly higher frequency in PCa patients than controls (palthy controls (43% vs. 14%, odds ratio=4.6, p=0.0001) and benign hyperplasia group (43% vs. 25%, odds ratio=2.2, p=0.009).Conclusion: Our study has highlighted the association of rs16901979 SNP with PCa in Saudi males. Such findings have important implications in the PCa diagnosis and in screening unaffected family members of Saudi patients.

关键词： Prostatecancer Saudi Singlenucleotide polymorphism allele

Prevalence of malignant neoplasms in celiac disease patients-a nationwide United States population-based study

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World Journal of Clinical Oncology 2024年第8期15卷 1048-1060页

作者： Maryam Bilal Haider ali al Sbihi Sushmitha Nanja Reddy Peter Green Department of Gastroenterology Northshore University Health SystemEvanstonIL 60201United States Department of Hematology/Oncology University of Miami Miller School of MedicineMiamiFL 33101United States Department of Hematology/Oncology Karmanos Cancer Institute/Wayne State UniversityDetroitMI 48235United States Celiac Disease Center Columbia UniversityNew YorkNY 10032United States

BACKGROUND Celiac disease(CeD)is an autoimmune disorder triggered by the immune response to gluten in genetically predisposed *** research has unveiled a heightened risk of developing specific malignant neoplasms(MN)and various malignancies,including gastrointestinal,lymphomas,skin,and others,in individuals with *** To investigate the prevalence of MN in hospitalized CeD patients in the United *** Using data from the National Inpatient Sample spanning two decades,from January 2000 to December 2019,we identified 529842 CeD patients,of which 78128(14.75%)had *** score matching,based on age,sex,race,and calendar year,was employed to compare CeD patients with the general non-CeD population at a 1:1 *** Positive associations were observed for several malignancies,including small intestine,lymphoma,nonmelanoma skin,liver,melanoma skin,pancreas myelodysplastic syndrome,biliary,stomach,and other neuroendocrine tumors(excluding small and large intestine malignant carcinoid),leukemia,uterus,and ***,CeD patients exhibited a reduced risk of respiratory and secondary ***,certain malignancies showed null associations with CeD,including head and neck,nervous system,esophagus,colorectal,anus,breast,malignant carcinoids,bone and connective tissues,myeloma,cervix,and ovary *** Our study is unique in highlighting the detailed results of positive,negative,or null associations between different hematologic and solid malignancies and ***,it offers insights into evolving trends in CeD hospital outcomes,shedding light on advancements in its management over the past two *** findings contribute valuable information to the understanding of CeD’s impact on health and healthcare utilization.

关键词： Celiac disease Malignant neoplasm Autoimmune disorder Hospitalized patients Healthcare utilization Gastrointestinal malignancies Lymphomas Epidemiology

Evolution of light deflection and shadow from a gauge-potential-like AdS black hole under the influence of a non-magnetic plasma medium

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Communications in Theoretical Physics 2024年第9期76卷 85-96页

作者： Riasat ali Xia Tiecheng Muhammad Awais Rimsha Babar Department of Mathematics Shanghai University and Newtouch Center for Mathematics of Shanghai University Department of Mathematics University of Engineering and Technology Department of Mathematics GC University Faisalabad Layyah Campus

We investigate the light deflection in the weak field approximation from the accelerating charged AdS black hole. For this purpose, we apply the Gauss–Bonnet theorem to calculate the light deflection in the weak field area and use the Gibbons–Werner approach to analyze the optical geometry of the accelerating charged AdS black hole in the non-magnetic plasma absence/presence of a non-magnetic medium. We also represent the graphical behavior of the light deflection angle w.r.t. the impact parameter. We also compute the light deflection angle using Keeton and Petters approximations under the impact of accelerating charged AdS black hole geometry. Furthermore, by using the ray-tracing approach, we determine the shadow in the nonmagnetic plasma presence and also demonstrate that graphical shadow has an impact on the gauge potential, non-magnetic plasma frequencies and charge.

关键词： accelerating charged AdS black hole deflection angle Gibbons-Werner approach ray-tracing approach shadow

Development of anti-corrosive coating on AZ31 Mg alloy modified by MOF/LDH/PEO hybrids

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Journal of Magnesium and alloys 2024年第2期12卷 586-607页

作者： Muhammad ali Khan Ananda Repycha Safira Mohammad Aadil Mosab Kaseem Corrosion and Electrochemistry Laboratory Department of Nanotechnology and Advanced Materials EngineeringSejong UniversitySeoul 05006Republic of Korea

The self-assembly of hybrid inorganic-organic materials on stationary platforms plays a critical role in improving their structural stability and wide *** this work,a novel two-step hydrothermal approach is proposed for synthesizing stable and advanced hybrid coatings on metal-oxide platforms through the surface modification of layered double hydroxide(LDH)films using novel metal-organic frameworks(MOFs).Initially,Mg-al LDH nanocontainers,grown on a magnesium oxide layer produced through plasma electrolytic oxidation(PEO)of AZ31 Mg alloy substrate,were intercalated with cobalt via an oxidation route,providing the metallic coordination center for the MOF *** the subsequent step,a pioneering technique is introduced,utilizing tryptophan as the organic linker for the first time at a pH of *** self-assembly of cobalt-tryptophan complex,driven by the strong bonding between electrophilic sites of monomers and nucleophilic sites,facilitated the formation of a MOF network having a cloud-like structure on the surface of Mgal LDH's *** resulting MOF-LDH encapsulation containers demonstrate exceptional electrochemical stability when exposed to a 3.5 wt.%NaCl solution,surpassing the performance of PEO and pure LDH *** enhanced stability is attributed to the development of a dense top layer and a stable composition within the self-assembled MOF,effectively sealing flaws and preventing the infiltration of corrosive ions into the underlying metallic *** formation mechanism of MOFs on LDH galleries is investigated using density functional theory calculations.

关键词： Mg alloy Layered double hydroxide Metal-organic frameworks Corrosion DFT

Solving the Water Resource Problems in Iraq

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Engineering（科研） 2024年第8期16卷 205-223页

作者： Nadhir al-Ansari Nasrat Adamo Varoujan Sissakian Jan Laue Salwan ali Abed Department of Civil Environmental and Natural Resources Engineering Lulea University of Technology Lulea Sweden Consultant Engineer Norrkoping Sweden Komar University of Science and Technology Sulaymaniyah Iraq College of Science University of Al-Qadisiyah Diwaniyah Iraq

Iraq covers an area of 437072 km2 in the northeastern part of the Middle East. Its population now is more than 40 million. It relies mainly on its water resources from the Tigris and Euphrates Rivers and their tributaries. Recently, Iraq has been experiencing a severe water scarcity problem. This is mainly due to climate change, increased hydrological projects in riparian countries, and water resources mismanagement inside Iraq itself. To overcome the problem, a new strategy should be implemented. Such strategy should consider two main courses of action: a) serious negotiations with riparian countries to reach an agreement giving Iraq equitable water shares from the Tigris and Euphrates Rivers and their tributaries. b) Prudent water management practices inside Iraq that consider adopting realistic distribution of water between the governorates, rational policies aiming at increased water use efficiencies within Irrigation networks, increased use of non-conventional sources of water, adjustment of water tariffs and their collection procedures, improving agricultural techniques, introduction of intensive guidance and public awareness programs, and promulgation of new legislations, in addition to creation of human resources development programs.

关键词： Tigris Rivers Euphrates Rivers Iraq

CRISPR,CAR-T,and NK:Current applications and future perspectives

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Genes & Diseases 2024年第4期11卷 246-257页

作者： Mohadeseh Khoshandam Hossein Soltaninejad Amir ali Hamidieh Saman Hosseinkhani Department of Reproductive Biology Academic Center for EducationCultureand Research(ACECR)Qom branch***Iran National Institute of Genetic Engineering and Biotechnology(NIGEB) Tehran 14965/161Iran Department of stem cells technology and Tissue Regeneration Faculty of Interdisciplinary Science and TechnologiesTarbiat Modares UniversityTehran 15614Iran Pediatric Cell Therapy and Gene Therapy Research Center GeneCell&Tissue Research InstituteTehran University of Medical SciencesTehran ***Iran Department of Biochemistry Faculty of Biological SciencesTarbiat Modares UniversityTehran 15614Iran

Chimeric antigen receptor T(CAR-T)cell therapy represents a breakthrough in personalized cancer *** this regard,synthetic receptors comprised of antigen recognition domains,signaling,and stimulatory domains are used to reprogram T-cells to target tum or cells and destroy *** the success of this approach in refractory B-cell malignancies,the optimal potency of CAR T-cell therapy for many other cancers,particularly solid tumors,has not been *** killer cells are powerful cytotoxic lymphocytes specialized in recognizing and dispensing the tumor cells in coordination with other anti-tumor immunity *** on these studies,many investigations are focused on the accurate designing of CAR T-cells with clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated protein 9(Cas9)system or other novel gene editing tools that can induce hereditary changes with or without the presence of a double-stranded break into the *** methodologies can be specifically focused on negative controllers of T-cells,induce modifications to a particular gene,and produce reproducible,safe,and powerful allogeneic CAR T-cells for on-demand cancer *** improvement of the CRISPR/Cas9 innovation offers an adaptable and proficient gene-editing capability in activating different pathways to help natural killer cells interact with novel CARs to particularly target tumor *** achievements and future challenges of combining next-generation CRISPR-Cas9 gene editing tools to optimize CAR T-cell and natural killer cell treatment for future clinical trials toward the foundation of modern cancer treatments have been assessed inthis review.

关键词： Cancer CAR T-cell CRISPR Gene editing Immunotherapy NK cell

Fully polarized Compton scattering in plane waves and its polarization transfer

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Matter and Radiation at Extremes 2024年第3期9卷 45-56页

作者： Suo Tang Yu Xin Meng Wen Mamat ali Bake Baisong Xie College of Physics and Optoelectronic Engineering Ocean University of ChinaQingdaoShandong 266100China Department of Physics Hubei UniversityWuhan 430062China Xinjiang Key Laboratory of Solid State Physics and Devices School of Physics Science and TechnologyXinjiang UniversityUrumqi 830017China Key Laboratory of Beam Technology of the Ministry of Education and College of Nuclear Science and TechnologyBeijing Normal UniversityBeijing 100875China

Fully polarized Compton scattering from a beam of spin-polarized electrons is investigated in plane-wave backgrounds in a broad intensity region from the perturbative to the nonperturbative *** the perturbative regime,polarized linear Compton scattering is considered for investigating polarization transfer from a single laser photon to a scattered photon,and in the high-intensity region,the polarized locally monochromatic approximation and locally constant field approximation are established and are employed to study polarization transfer from an incoming electron to a scattered *** numerical results suggest an appreciable improvement of about 10%in the scattering probability in the intermediate-intensity region if the electron’s longitudinal spin is parallel to the laser *** longitudinal spin of the incoming electron can be transferred to the scattered photon with an efficiency that increases with laser intensity and collisional *** collision between an optical laser with frequency1 eV and a 10 GeV electron,this polarization transfer efficiency can increase from about 20%in the perturbative regime to about 50%in the nonperturbative regime for scattered photons with relatively high energy.

关键词： polarized scattered transfer