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COVID-19 in the endoscopy unit:How likely is transmission of infection?Results from an international,multicenter study

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World Journal of Gastrointestinal Endoscopy 2021年第9期13卷 416-425页

作者： Ioannis s Papanikolaou Georgios Tziatzios alexandros Chatzidakis Antonio Facciorusso stefano Francesco Crinò Paraskevas Gkolfakis Gjorgi Deriban Mario Tadic Goran Hauser Antonios Vezakis Ivan Jovanovic Nicola Muscatiello Anna Meneghetti Konstantinos Miltiadou Kalina stardelova Alojzije Lacković Maria-Zoi Bourou srdjan Djuranovic Konstantinos Triantafyllou Hepatogastroenterology Unit 2nd Department of Internal Medicine-PropaedeuticNational and Kapodistrian University of Athens"Attikon"University General HospitalAthens 12462Greece Gastroenterology Unit Department of Surgical and Medical SciencesUniversity of Foggia AOUFoggia 1245Italy Gastroenterology and Digestive Endoscopy Unit The Pancreas InstituteUniversity of VeronaVerona 37138Italy Department of Gastroenterology Hepatopancreatology and Digestive OncologyErasme University HospitalUniversitéLibre de BruxellesBrussels 1070Belgium Department of Medical Oncology Institut Jules BordetBrussels 1000Belgium University Clinic of Gastroenterohepatology Medical FacultyUniversity"Ss.Cyril and Methodius"SkopjeSkopje 12345Republic of North Macedonia Department of Gastroenterology Dubrava University Hospital ZagrebZagreb 10040Croatia Clinical Hospital Center Rijeka Faculty of MedicineUniversity of RijekaRijeka 51000Croatia 2nd Department of surgery Aretaieio HospitalSchool of MedicineNational and Kapodistrian University of AthensAthens 11528Greece Clinical Center of serbia Clinic for Gastroenterology and HepatologyUniversity of Belgrade Faculty of MedicineBeograd 12345Serbia

BACKGROUND Coronavirus disease 2019(COVID-19)significantly affected endoscopy practice,as gastrointestinal endoscopy is considered a risky procedure for transmission of infection to patients and personnel of endoscopy units(PEU).AIM To assess the impact of COVID-19 on endoscopy during the first European lockdown(March-May 2020).METHODs Patients undergoing endoscopy in nine endoscopy units across six European countries during the period of the first European lockdown for COVID-19(March-May 2020)were *** to the endoscopy procedure,participants were stratified as low-or high-risk for potential COVID-19 infection according to the European society of Gastrointestinal Endoscopy(EsGE)and the European society of Gastroenterology and Endoscopy Nurses and Associates(EsGENA)joint statement,and contacted 7-14 d later to assess COVID-19 infection *** were questioned regarding COVID-19 symptoms and/or infection via questionnaire,while information regarding hospitalizations,intensive care unitadmissions and COVID-19-related deaths were *** number of weekly endoscopies at each center during the lockdown period was also *** A total of 1267 endoscopies were performed in 1222 individuals across nine European endoscopy departments in six ***-seven(7%)were excluded because of initial positive *** the 1135 pre-endoscopy low risk or polymerase chain reaction negative for COVID-19,254(22.4%)were tested post endoscopy and 8 were eventually found positive,resulting in an infection rate of 0.7%[95%CI:0.2-0.12].The majority(6 of the 8 patients,75%)had undergone *** the 163 PEU,5[3%;(95%CI:0.4-5.7)]tested positive during the study period.A decrease of 68.7%(95%CI:64.8-72.7)in the number of weekly endoscopies was recorded in all centers after March *** centers implemented appropriate personal protective measures(PPM)from the initial phases of the *** COVID-19 transmission in endoscopy unit

关键词： COVID-19 sARs-CoV-2 Gastrointestinal endoscopy Personal protection measures Transmission Lockdown

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The Big Five Model in Relation to Job Performance:A New Look at Organizational Psychology

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Psychology Research 2023年第1期13卷 1-8页

作者： Bafetis alexandros Michael Galanakis Deree The American College of GreeceAthensGreece

The Big Five Theory is often regarded as psychology’s most influential personality theoretical *** goal of this study is to examine the role of the Big Five Theory in the workplace,especially which personality qualities are more likely to predict work *** traits should companies emphasize throughout the hiring and selection processes?How can businesses use the Big Five personality model to locate employees that are more productive,efficient,and devoted to the organization’s goals?A detailed assessment of existing recent research addresses the aforementioned *** a review of many current articles on the subject,it was established that using this model had a positive influence on individual and group performance,working relationships,manager work performance,and workplace innovation.

关键词： organizational psychology personality Big Five Model job performance

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A modelling study for the integration of a PEMFC microCHP in domestic building services design

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建筑节能(中英文) 2018年第9期 136-136页

作者： alexandros Adam Eric s.Fraga Dan J.L.Brett 侯恩哲《建筑节能》杂志社

Fuel cell based micro-combined heat and power( CHP) units used for domestic applications can provide significant cost and environmental benefits for end users and contribute to the UK 's 2050 emissions target by reducing primary energy consumption in dwellings. Lately there has been increased interest in the development of systematic methods for the design of such systems and their smoother integration with domestic building services. several models in the literature,whether they use a simulation or an optimisation approach,ignore the dwelling side of the system and optimise the efficiency or delivered power of the unit. However the design of the building services is linked to the choice of heating plant and its characteristics. Adding the dwelling's energy demand and temperature constraints in a model canproduce more general results that can optimise the whole system,not only the micro-CHP unit. The fuel cell has various heat streams that can be harvested to satisfy heat demand in a dwelling and the design can vary depending on the proportion of heat needed from each heat stream to serve the energy demand. A mixed integer non-linear programming model( M INLP) that can handle multiple heat sources and demands is presented in this *** methodology utilises a process systems engineering approach. The model can provide a design that integrates the temperature and water flowconstraints of a dwelling's heating system with the heat streams within the fuel cell processes while optimising total CO2 emissions. The model is demonstrated through different case studies that attempt to capture the variability of the housing stock. The predicted CO2 emissions reduction compared to a conventionally designed building vary from 27%to 30%and the optimum capacity of the fuel cell ranges between 1. 9 kW and3. 6 kW. This research represents a significant step towards an integrated fuel cell micro-CHP and dwelling design.

关键词： Fuel cell Residential Microgeneration Energy demand

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High-resolution microendoscopy for esophageal cancer screening in China: A cost-effectiveness analysis

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World Journal of Gastroenterology 2015年第18期21卷 5513-5523页

作者： Chin Hur sung Eun Choi Chung Yin Kong Gui-Qi Wang Hong Xu alexandros D Polydorides Li-Yan Xue Katherine E Perzan Angela C Tramontano Rebecca R Richards-Kortum sharmila Anandasabapathy Institute for Technology Assessment Massachusetts General Hospital Harvard Medical school Boston MA 02114 United States Gastrointestinal Unit Massa- chusetts General Hospital Department of Endoscopy Cancer Institute and Hospital Chinese Academy of Medical Sciences Department of Endoscopy The First Hospital of Jilin University Department of Pathology The Mount Sinai Medical Center Icahn School of Medicine Department of Pathology Cancer Institute and Hospital Chinese Academy of Medical Sciences Department of Bioengineering Rice University Baylor Global Initiatives and the Baylor Global Innovation Center Baylor College of Medicine

AIM:To study the cost-effectiveness of high-resolution microendoscopy(HRME)in an esophageal squamous cell carcinoma(EsCC)screening program in ***:A decision analytic Markov model of EsCC was *** model analyses were conducted for cohorts consisting of an averagerisk population or a high-risk population in *** 50-year-old individuals were followed until age 80 or *** compared three different strategies for both cohorts:(1)no screening;(2)standard endoscopic screening with Lugol’s iodine staining;and(3)endoscopic screening with Lugol’s iodine staining and an *** parameters were estimated from the literature as well as from GLOBOCAN,the Cancer Incidence and Mortality Worldwide cancer *** states in the model included non-neoplasia,mild dysplasia,moderate dysplasia,high-grade dysplasia,intramucosal carcinoma,operable cancer,inoperable cancer,and *** EsCC incidence transition rates were generated for the average-risk and high-risk *** in Chinese currency were converted to international dollars(I$)and were adjusted to 2012dollars using the Consumer Price ***:The main outcome measurements for this study were quality-adjusted life years(QALYs)and incremental cost-effectiveness ratio(ICER).For the average-risk population,the HRME screening strategy produced 0.043 more QALYs than the no screening strategy at an additional cost of I$646,resulting in an ICER of I$11808 per QALY *** endoscopic screening was weakly *** the high-risk population,when the HRME screening strategy was compared with the standard screening strategy,the ICER was I$8173 per *** both the high-risk and average-risk screening populations,the HRME screening strategy appeared to be the most cost-effective strategy,producing ICERs below the willingness-topay threshold,I$23500 per ***-way sensitivity analysis showed that,for the average-risk population,higher specificity of Lugol’s i

关键词： Cost-effectiveness analysis Diagnostic imaging Endoscopy Esophageal squamous cell cancer simulation disease model

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Melatonin attenuates high fat diet-induced fatty liver disease in rats

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World Journal of Hepatology 2013年第4期5卷 160-169页

作者： Gregorios Hatzis Panayiotis Ziakas Nikolaos Kavantzas Aggeliki Triantafyllou Panagiotis sigalas Ioanna Andreadou Konstantinos Ioannidis stamatios Chatzis Konstantinos Filis alexandros Papalampros Fragiska sigala Department of Pathophysiology Athens University School of Medicine11527 AthensGreece Department of Pathology Athens University School of Medicine11527 AthensGreece Department of Biological Chemistry Athens University School of Medicine11527 AthensGreece Department of Pharmaceutical Chemistry Athens University School of PharmacyPanepistimiopolis of ZographouZografou15771 AthensGreece 1~(st) Department of Propaedeutic surgery Athens University School of Medicine11527 AthensGreece 1~(st) Department of surgery Athens University School of Medicine11527 AthensGreece

AIM:To investigate melatonin's preventive action in oxidative stress in a rat model with high fat diet-induced non-alcoholic fatty liver disease(NAFLD).METHODs:NAFLD was induced by high fat diet(HFD)in adult,male,Wistar rats,weighing 180-230 *** acclimatization for one week,they were randomly assigned to 6 experimental groups that comprised animals on regular diet plus 5 or 10 mg/kg melatonin,for 4 or 8 wk;animals on HFD,with or without 5 or 10 mg/kg melatonin,for 4 or 8 wk;and animals on HFD for 8 or 12 wk,with melatonin 10 mg/kg for the last 4 *** damage was assessed biochemically by the serum levels of alanine aminotransferase(ALT),aspartate aminotransferase(AsT),and *** peroxidation and oxidative stress were assessed by malondialdehyde and glutathione levels in liver *** indices and portal vein pressure were also ***:Compared to rats not receiving melatonin,rats on 5 or 10 mg/kg of melatonin had lower mean liver weight(-5.0 g and-4.9 g)(P ses,*** rats fed HFD without melatonin developed severe,grade Ⅲ,*** on HFD with concurrent use of melatonin showed significantly less steatosis,with grade Ⅲ steatosis observed in 1 of 29(3.4%)rats on 10 mg/kg melatonin and in 3 of 27(11.1%)rats on 5 mg/kg *** was ineffective in reversing established *** also had no effect on any of the common lipidemic serum markers,the levels of which did not differ significantly among the rats on HFD,irrespective of the use or not of *** cell necrosis was significantly less in rats on HFD receiving melatonin than in those not on melatonin,with the AsT levels declining by a mean of 170 U/L(P = 0.01)and 224 U/L(P = 0.001),and the ALT levels declining by a mean of 62.9 U/L(P = 0.01)and 93.4 U/L(P se,*** mitigated liver damage due to

关键词： Melatonin Non-alcoholic fatty liver disease Oxidative stress Metabolic syndrome Portal vein pressure Lipid peroxidation Antioxidants

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Innovative Education and Training in high power laser plasmas(PowerLaPs) for plasma physics, high power laser-matter interactions and high energy density physics-theory and experiments

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High Power Laser science and Engineering 2019年第2期7卷 22-26页

作者： John Pasley Georgia Andrianaki Andreas Baroutsos Dimitri Batani Emmanouil P.Benis Marco Borghesi Eugene Clark Donna Cook Emmanuel D'Humieres Vasilios Dimitriou Brendan Dromey Michael Ehret Ioannis Fitilis Anastasios Grigoriadis satya Kar Evaggelos Kaselouris Ondrej Klimo Michel Koenig Kyriaki Kosma George Koundourakis Milan Kucharik Aveen Lavery Jiri Limpouch Yannis Orphanos Nektarios A.Papadogiannis stelios Petrakis Dave Riley Maria serena Rivetta Laura Tejada Pascual Joao Jorge santos alexandros skoulakis Ioannis Tazes Vladimir Tikhonchuk Jocelain Trela Calliope Tsitou Luca Volpe steven White Mark Yeung Michael Tatarakis York Plasma Institute University of York Technological Educational Institute of Crete School of Applied SciencesCentre for Plasma Physics and Lasers-CPPL Universitéde Bordeaux CNRSCEACELIA(Centre Lasers Intenses et Applications) Department of Physics University of Ioannina Centre for Plasma Physics School of Mathematics and PhysicsQueen’s University Belfast Faculty of Nuclear sciences and Physical Engineering Czech Technical University in Prague LULI-CNRs Ecole Polytechnique CEA:UniversitéParis-Saclay UPMC Univ Paris 06:sorbonne Universités CLPU Laser-Plasma Chair University of Salamanca Centro de Láseres Pulsados(CLPU) Edificio M5.Parque Cientfico.C/Adaja

The Erasmus Plus programme’Innovative Education and Training in high power laser plasmas’,otherwise known as PowerLaPs,is *** PowerLaPs programme employs an innovative paradigm in that it is a multi-centre programme where teaching takes place in five separate institutes with a range of different aims and styles of *** ’in class’ time is limited to four weeks a year,and the programme spans two *** aims to train students from across Europe in theoretical,applied and laboratory skills relevant to the pursuit of research in laserplasma interaction physics and inertial confinement fusion(ICF).Lectures are intermingled with laboratory sessions and continuous assessment *** programme,which is led by workers from the Technological Educational Institute(TEI)of Crete,and supported by co-workers from the Queen’s University Belfast,the University of Bordeaux,the Czech Technical-University in Prague,Ecole Polytechnique,the University of Ioannina,the University of salamanca and the University of York,has just completed its first *** far three Learning Teaching Training(LTT)activities have been held,at the Queen’s University Belfast,the University of Bordeaux and the Centre for Plasma Physics and Lasers(CPPL)of TEI *** last of these was a two-week long Intensive Programme(IP),while the activities at the other two universities were each five days in *** far work has concentrated upon training in both theoretical and experimental work in plasma physics,high power laser-matter interactions and high energy density *** nature of the programme will be described in detail and some metrics relating to the activities carried out to date will be presented.

关键词： higher education inertial confinement fusion laser-plasma interactions post-graduate education

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Innovative education and training in high power laser plasmas(PowerLaPs) for plasma physics, high power laser matter interactions and high energy density physics: experimental diagnostics and simulations

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High Power Laser science and Engineering 2020年第1期8卷 30-36页

作者： John Pasley Georgia Andrianaki Andreas Baroutsos Dimitri Batani Emmanouil PBenis Andrea Ciardi Donna Cook Vasilios Dimitriou Brendan Dromey Ioannis Fitilis Giancarlo Gatti Anastasios Grigoriadis Marine Huault Jose Antonio Pérez Hernández Evaggelos Kaselouris Ondrej Klimo Michel Koenig George Koundourakis Milan Kucharik Jiri Limpouch Richard Liska Carlos salgado Lopez sophia Malko susana Olmos-Miguelanez Yannis Orphanos Valeria Ospina Nektarios APapadogiannis stelios Petrakis Jan Psikal Maria serena Rivetta Maria-ose Rodriguez-Conde Joao Jorge santos Milan sinor alexandros skoulakis Ioannis Tazes Laura Tejada Pascual Calliope Tsitou Pavel Vachal Luca Volpe Jiri Vyskocil steven White Mark Yeung Ghassan Zerouli Michael Tatarakis York Plasma Institute University of YorkHeslingtonYork YO105DQUK Hellenic Mediterranean University Institute of Plasma Physics and Lasers-IPPL74100 Rethymnon73133 ChaniaCreteGreece University of Bordeaux CNRSCEACELIA(Centre Lasers Intenses et Applications)UMR 5107F-33405 TalenceFrance Department of Physics University of IoanninaGR 45110 IoanninaGreece LULI-CNRs CEASorbonne UniversiesEcole PolytechniqueInstitut Polytechnique de Paris-F-91128 Palaiseau CedexFrance Observatoire de Paris 5 Place J JanssenMeudon 92195France Centre for Plasma Physics School of Mathematics and PhysicsQueen’s University BelfastBelfast BT71NNUK Centro de Láseres Pulsados(CLPU) Edificio M5Parque CientficoC/Adaja 837185 VillamayorSalamancaSpain University of salamanca 37008 SalamancaSpain Faculty of Nuclear sciences and Physical Engineering Czech Technical University in PragueBrehova 711519Prague 1Czech Republic University Institute for Educational sciences University of Salamanca37008 SalamancaSpain Group of Research“Interaction and e Learning”(GRIAL) University of Salamanca37008 SalamancaSpain CLPU Laser-Plasma Chair at University of salamanca 37008 SalamancaSpain

The second and final year of the Erasmus Plus programme’Innovative Education and Training in high power laser plasmas’,otherwise known as PowerLaPs,is *** PowerLaPs programme employs an innovative paradigm in that it is a multi-centre programme,where teaching takes place in five separate institutes with a range of different aims and styles of ***’in-class’time is limited to 4 weeks a year,and the programme spans 2 *** aims to train students from across Europe in theoretical,applied and laboratory skills relevant to the pursuit of research in laser plasma interaction physics and inertial confinement *** are intermingled with laboratory sessions and continuous assessment *** programme,which is led by workers from the Hellenic Mediterranean University and supported by co-workers from the Queen’s University Belfast,the University of Bordeaux,the Czech Technical University in Prague,Ecole Polytechnique,the University of Ioannina,the University of salamanca and the University of York,has just finished its second and final *** Learning Teaching Training activities have been held at the Queen’s University Belfast,the University of Bordeaux,the Czech Technical University,the University of salamanca and the Institute of Plasma Physics and Lasers of the Hellenic Mediterranean *** last of these institutes hosted two 2-week-long Intensive Programmes,while the activities at the other four universities were each 5 days in *** addition,a’Multiplier Event’was held at the University of Ioannina,which will be briefly *** this second year,the work has concentrated on training in both experimental diagnostics and simulation techniques appropriate to the study of plasma physics,high power laser matter interactions and high energy density *** nature of the programme will be described in detail,and some metrics relating to the activities carried out will be *** particular,this paper will f

关键词： laser plasma interactions postgraduate education

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sub-percent precision measurement of neutrino oscillation parameters with JUNO

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Chinese Physics C 2022年第12期46卷 28-49页

作者： Angel Abusleme Thomas Adam shakeel Ahmad Rizwan Ahmed sebastiano Aiello Muhammad Akram Abid Aleem Fengpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Weidong Bai Nikita Balashov Wander Baldini Andrea Barresi Davide Basilico Eric Baussan Marco Bellato Antonio Bergnoli Thilo Birkenfeld sylvie Blin David Blum simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Jose Busto Ilya Butorov Anatael Cabrera Barbara Caccianiga Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Riccardo Callegari Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Chi Chan Jinfan Chang Yun Chang Guoming Chen Pingping Chen Po-An Chen shaomin Chen Xurong Chen Yixue Chen Yu Chen Zhiyuan Chen Zikang Chen Jie Cheng Yaping Cheng Yu Chin Cheng Alexey Chetverikov Davide Chiesa Pietro Chimenti Artem Chukanov Gérard Claverie Catia Clementi Barbara Clerbaux selma Conforti Di Lorenzo Daniele Corti Flavio Dal Corso Olivia Dalager Christophe De La Taille Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara sergey Dmitrievsky Tadeas Dohnal Dmitry Dolzhikov Georgy Donchenko Jianmeng Dong Evgeny Doroshkevich Marcos Dracos Frédéric Druillole Ran Du shuxian Du stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Donghua Fan Lei Fan Jian Fang Wenxing Fang Marco Fargetta Dmitry Fedoseev Zhengyong Fei Li-Cheng Feng Qichun Feng Richard Ford Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Arsenii Gavrikov Marco Giammarchi Nunzio Giudice Maxim Gonchar Guanghua Gong Hui Gong Yuri Gornushkin Alexandre Göttel Marco Grassi Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Yuduo Guan Nunzio Guardone Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yang Han Miao He Wei He Tobias Heinz Patrick Hellmuth Yuekun Heng Rafael Herrera YuenKeung Ho Yerevan Physics Institute YerevanArmenia UniversiéLibre de Bruxelles BrusselsBelgium Universidade Estadual de Londrina LondrinaBrazil Pontificia Universidade Catolica do Rio de Janeiro Rio de JaneiroBrazil Pontificia Universidad Católica de Chile SantiagoChile Universidad Tecnica Federico santa Maria ValparaisoChile Beijing Institute of spacecraft Environment Engineering BeijingChina Beijing Normal University BeijingChina China Institute of Atomic Energy BeijingChina Institute of High Energy Physics BeijingChina North China Electric Power University BeijingChina school of Physics Peking UniversityBeijingChina Tsinghua University BeijingChina University of Chinese Academy of sciences BeijingChina Jilin University ChangchunChina College of Electronic science and Engineering National University of Defense TechnologyChangshaChina Chongqing University ChongqingChina Dongguan University of Technology DongguanChina Jinan University GuangzhouChina sun Yat-sen University GuangzhouChina Harbin Institute of Technology HarbinChina University of science and Technology of China HefeiChina The Radiochemistry and Nuclear Chemistry Group in University of south China HengyangChina Wuyi University JiangmenChina shandong University JinanChinaand Key Laboratory of Particle Physics and Particle Irradiation of Ministry of EducationShandong UniversityQingdaoChina Institute of Modern Physics Chinese Academy of SciencesLanzhouChina Nanjing University NanjingChina Guangxi University NanningChina East China University of science and Technology ShanghaiChina school of Physics and Astronomy Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai University TianjinChina Wuhan University WuhanChina Xi'an Jiaotong University Xi'anChina Xiamen University XiamenChina school of Physics and Microelectronics Zhengzhou UniversityZhengzhou

JUNO is a multi-purpose neutrino observatory under construction in the south of *** publication presents new sensitivity estimates for the measurement of the △m_(31)^(2),△m_(21)^(2),sin^(2)θ_(12),and sin^(2)θ_(13) oscillation parameters using reactor antineutrinos,which is one of the primary physics goals of the *** sensitivities are obtained using the best knowledge available to date on the location and overburden of the experimental site,the nuclear reactors in the surrounding area and beyond,the detector response uncertainties,and the reactor antineutrino spectral shape constraints expected from the TAO satellite *** is found that the △m_(21)^(2) and sin^(2)θ_(12) oscillation parameters will be determined to 0.5%precision or better in six years of data *** the same period,the △m_(31)^(2) parameter will be determined to about 0.2%precision for each mass ordering *** new precision represents approximately an order of magnitude improvement over existing constraints for these three parameters.

关键词： neutrino oscillation reactor antineutrino precision measurement JUNO

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