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传染病网络动态 2002年第10期 36-36页

作者： alexandra,m 杨露绮

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玻璃纤维的节能无甲醛涂层技术

国际纺织导报 2020年第2期48卷 24-26页

作者： m.Karnop A.Abele 吴雯雯(译) 于俊荣(校) Synthomer公司(德国) 不详

对于下一代玻璃纤维涂层,化学工业界正在寻找集高性能、低能耗和挥发性有机化合物(VOC)排放量大幅减少于一体的单一产品的可能性。Synthomer公司现已开发出一种不含甲醛的玻璃纤维涂层技术,实现了更优的涂层性能和更高的工艺效率。

关键词：玻璃纤维无甲醛涂层技术

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右美托咪啶镇静对小儿心血管系统的影响

麻醉与镇痛 2013年第5期9卷 15-21页

作者： Jackson Wong, mD Garry m. Steil, PhD michelle Curtis, PNP alexandra Papas, BS David Zurakowski, PhD Keira P. mason, mD 郭志佳(译) 郭政(校) Department of medicine Medicine Critical Care Program Children's Hospital Boston and Harvard Medical School Boston MA Children's Hospital Boston Boston MA Children Hospital Boston and Harvard medical School Boston MA Department of Anesthesia Children Hospital Boston and Harvard Medical School Boston MA

背景右美托咪啶（dexmedetomidine，DEX）可影响成年人的心率（heartrate，HR）、平均动脉压、心脏指数（cardiacindex，CI）、心搏指数（strokeindex，SI）和体循环血管阻力指数（systemicvascularresistanceindex，SVRI）。本研究旨在探讨DEX镇静对小儿心血管系统是否存在类似作用。方法给予DEX后使用影像学方法监测小儿血流动力学的变化。第一组（DEX．短时）8例患者接受DEX2μg/kg于10分钟内输注完毕且手术在10分钟内完成；第二组（DEX．长时）9例患者在首次给药（DEX2μg／kg）的基础上按需追加DEX1μg／（kg·h），手术时间超过10分钟。使用无创心排血量探头监测CI、SI、SVRI。用重复测量的方差分析比较10分钟、20分钟和出室（Aldrete评分达9）3个时间点血流动力学与基础数值的差异，数据以均数表示（可信区间95％）。结果DEX-短时组共8例，DEX．长时组共9例。在DEX-短时组，T1点的HR和C1分别降低了18．9（2．3～35．5）次／分和0．74（0．15—1．33）L／（min·m2），其余无显著变化，所有指标在R，点都恢复到基础值。在DEX．长时组，HR、CI降低持续至恢复期[分别降低了24．0（8．3—39．6）次／分、1．51（0．95～2．06）L／（min·m2）]；同时，恢复期的SI降低8．0l（1．71-14．31）ml／m2，而SVRI升高[776．0（271．9—1280．4）dyn-s／（cm5·m2）]。两组的平均动脉压均未见显著变化。结论DEX使小儿Cl降低，且有累积效应。对于接受长时间手术的患者，胍、CI持续降低到患者出室，同时伴随SI降低、SVRI升高。

关键词：心血管系统右美托咪啶小儿镇静平均动脉压血流动力学血管阻力指数心脏指数

Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration

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World Journal of Gastroenterology 2014年第47期20卷 17851-17862页

作者： Katharine m Irvine Richard Skoien Nilesh J Bokil michelle melino Gethin P Thomas Dorothy Loo Brian Gabrielli michelle m Hill matthew J Sweet Andrew D Clouston Elizabeth E Powell Centre for Liver Disease Research School of MedicineThe University of QueenslandTranslational Research InstituteBrisbane 4102Australia Institute for molecular Bio-science The University of QueenslandBrisbane 4067Australia The University of Queensland Diamantina Institute The University of Queensland Translational Research InstituteBrisbane 4102Australia Department of Gastroenterology and Hepatology Princess Alexandra HospitalBrisbane 4102Australia

AIm: To develop a model of stress-induced senescence to study the hepatocyte senescence associated secretory phenotype (SASP).

关键词： Cell aging Chemokines Hepatocytes Inflammation Liver diseases macrophages

微量矿物元素来源对肉鸡生物学利用率参数影响的研究

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中国饲料添加剂 2020年第5期 34-38页

作者：解玉怀王丽雪杨维仁(译) 山东农业大学动物科技学院山东省动物生物工程与疾病防治重点试验室山东泰安271018

本研究旨在调查两种来源的铜、铁、锰和锌对肉鸡畜牧学性能的影响,以及通过消耗-补充研究设计来研究对表观总肠道消化率(ATTD),以及此微量元素在肝脏、胫骨(TB)、胸肌和皮肤中的沉积。将72只1日龄雄性肉鸡(CoW)500)分为3组。14天的消耗... 详细信息

本研究旨在调查两种来源的铜、铁、锰和锌对肉鸡畜牧学性能的影响,以及通过消耗-补充研究设计来研究对表观总肠道消化率(ATTD),以及此微量元素在肝脏、胫骨(TB)、胸肌和皮肤中的沉积。将72只1日龄雄性肉鸡(CoW)500)分为3组。14天的消耗期仅饲喂日粮天然成分中的微量元素,随后的14天,其中两组补充甘氨酸结合的(Gly)或硫酸盐结合的(Sul)微量元素。第三组补充充足的日粮,但不添加微量矿物质(对照组)。相比于基础日粮组,补充微量矿物质可改善体重(Pmn的ATTD高于对照组(Pmn和Fe的沉积率显著升高(Pmn、Zn和Cu利用率较高。结果表明,比较不同来源的矿物元素,其所测定的指标显示可影响生物利用率。

关键词：微量元素肉鸡性能消化率沉积率

Independent effects of diet and exercise training on fat oxidation in non-alcoholic fatty liver disease

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World Journal of Hepatology 2016年第27期8卷 1137-1148页

作者： Ilaria Croci Nuala m Byrne Veronique S Chachay Andrew P Hills Andrew D Clouston Trisha m O'moore-Sullivan Johannes B Prins Graeme A macdonald Ingrid J Hickman School of Human movement and Nutrition Sciences University of Queensland Translational Research Institute the University of Queensland Diamantina Institute Bond Institute of Health and Sport Bond University Institute of Health and Biomedical Innovation Queensland University of Technology School of Health Sciences University of Tasmania mater Research Institute University of Queensland School of medi-cine the University of Queensland Department of Gastroenterology and Hepatology Princess Alexandra Hospital Translational Research Institute Department of Nutrition and Dietetics Princess Alexandra Hospital

AIm To investigate the independent effects of 6-mo of dietary energy restriction or exercise training on wholebody and hepatic fat oxidation of patients with nonalcoholic fatty liver disease(NAFLD).mETHODS Participants were randomised into either circuit exercise training(EX;n = 13;3 h/wk without changes in dietary habits),or dietary energy restriction(ER) without changes in structured physical activity(ER;n = 8).Respiratory quotient(RQ) and whole-body fat oxidation rates(Fatox) were determined by indirect calorimetry under basal,insulin-stimulated and exercise *** of disease and steatosis was determined by liver histology;hepatic Fatox was estimated from plasma β-hydroxybutyrate ***;cardiorespiratory fitness was expressed as VO2 ***-case analysis was performed(EX:n = 10;ER:n = 6).RESULTS Hepatic steatosis and NAFLD activity score decreased with ER but not with EX.β-hydroxybutyrate concentrations increased significantly in response to ER(0.08 ± 0.02 mmol/L vs 0.12 ± 0.04 mmol/L,P = 0.03) but remained unchanged in response to EX(0.10 ± 0.03 mmol/L vs 0.11 ± 0.07 mmol/L,P = 0.39).Basal RQ decreased(P = 0.05) in *** EX,while this change was not significant after ER(P = 0.38).VO_(2peak)(P maximal Fa_(tox) during aerobic exercise(P = 0.03) improved with EX but not with ER(P > 0.05).The increase in β-hydroxybutyrate concentrations was correlated with the reduction in hepatic steatosis(r =-0.56,P = 0.04).CONCLUSION ER and EX lead to specific benefits on fat metabolism of patients with *** hepatic Fat_(ox) in response to ER could be one mechanism through which the ER group achieved reduction in steatosis.

关键词： Non-alcoholic steatohepatitis Steatosis Fat and carbohydrate oxidation Exercise Fitness Beta-hydroxybutyrate Ketone bodies Fatty acid oxidation

Empirical estimates of regional carbon budgets imply reduced global soil heterotrophic respiration

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National Science Review 2021年第2期8卷 60-73页

作者： Philippe Ciais Yitong Yao Thomas Gasser Alessandro Baccini Yilong Wang Ronny Lauerwald Shushi Peng Ana Bastos Wei Li Peter A.Raymond Josep G.Canadell Glen P.Peters Rob J.Andres Jinfeng Chang Chao Yue A.Johannes Dolman Vanessa Haverd Jens Hartmann Goulven Laruelle alexandra G.Konings Anthony W.King Yi Liu Sebastiaan Luyssaert Fabienne maignan Prabir K.Patra Anna Peregon Pierre Regnier Julia Pongratz Benjamin Poulter Anatoly Shvidenko Riccardo Valentini Rong Wang Grégoire Broquet Yi Yin Jakob Zscheischler Bertrand Guenet Daniel S.Goll Ashley-P.Ballantyne Hui Yang Chunjing Qiu Dan Zhu State Key Laboratory of Soil Erosion and Dryland Farming on the Loess Plateau Northwest A&F University CSIRO Oceans and Atmosphere 15. Institute for Geology CEN—Center for Earth System Research and SustainabilityUniversity of Hamburg 16. Department of Earth System ScienceStanford University 17. Department of Earth System ScienceStanford UniversityStanford 18. School of Geographical SciencesNanjing University of Information Science and Technology 19. Department of Ecological SciencesVrije Universiteit Amsterdam 20. Research Institute for Global ChangeJAMSTEC Laboratoire des Sciences du Climat et de l'Environnement CEA-CNRS-UVSQ-UPSACLAY Center for Environmental Remote Sensing Chiba University Institute of Soil Science and Agrochemistry Siberian Branch of the Russian Academy of Sciences (SB RAS) Tuva State University Republic of Tuva max Planck Institute for meteorology NASA Goddard Space Flight Center Biospheric Sciences Lab. 26. Department for Innovation in BiologicalAgro-food and Forest systems (DIBAF)University of Tuscia RUDN University Department of Environmental Science and Engineering Shanghai Key Laboratory of Atmospheric Particle Pollution and PreventionInstitute of Atmospheric SciencesFudan University 29. Division of Geological and Planetary SciencesCalifornia Institute of Technology 30. Climate and Environmental Physics and Oeschger Centre for Climate Change ResearchUniversity of Bern 31. Department of Ecosystem and Conservation Sci

Resolving regional carbon budgets is critical for informing land-based mitigation policy. For nine regions covering nearly the whole globe, we collected inventory estimates of carbon-stock changes complemented by satellite estimates of biomass changes where inventory data are missing. The net land–atmospheric carbon exchange(NEE) was calculated by taking the sum of the carbon-stock change and lateral carbon fluxes from crop and wood trade, and riverine-carbon export to the ocean. Summing up NEE from all regions, we obtained a global ‘bottom-up’ NEE for net land anthropogenic CO2uptake of –2.2 ± 0.6 Pg C yr-1consistent with the independent top-down NEE from the global atmospheric carbon budget during 2000–2009. This estimate is so far the most comprehensive global bottom-up carbon budget accounting, which set up an important milestone for global carbon-cycle studies. By decomposing NEE into component fluxes, we found that global soil heterotrophic respiration amounts to a source of CO2of 39 Pg C yr-1with an interquartile of 33–46 Pg C yr-1—a much smaller portion of net primary productivity than previously reported.

关键词： carbon budget human appropriation of ecosystems soil carbon

Energy retrofit and conservation of a historic building using multi-objective optimization and an analytic hierarchy process

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建筑节能 2017年第3期45卷 9-9页

作者： Francesca Roberti Ulrich Filippi Oberegger Elena Lucchi alexandra Troi 侯恩哲 <建筑节能>杂志社

When deciding on the best historic building retrofit,energy savings and thermal comfort can be quantitatively evaluated using an energy model,whereas conservation compatibility is intrinsically qualitative and reflects the perspective of the local heritage authority. We present a methodology that permits finding and comparing optimal retrofits for historic buildings in a multi-perspective and quantitative way. We use an analytic hierarchyprocess to quantify conservation compatibility by distilling a conservation score from the opinions of 10 experts in the field. This score,along with energy needs for heating and cooling and thermal comfort,are the three targets of a multi-objective optimization aimed at identifying optimal retrofits for a medieval building in the north of Italy,destined to become a museum. Retrofit measures considered were different kinds of external and internal envelope insulation,improvement of airtightness,replacement of windows,and ventilative cooling. The result is a portfolio of optimal retrofits that cover the whole range of conservation compatibility. We showthat in the analyzed case heritage preservation is compatible with a four-fold reduction in energy needs at a high thermal comfort level. Even higher energy savings are only achievable at the cost of heritage degradation.

关键词：《建筑节能》英文摘要编辑工作期刊

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医患对心理问题识别的差异及其相关因素研究

医患对心理问题识别的差异及其相关因素研究

Ophthalmic manifestations in seropositive dengue fever patients during epidemics caused by predominantly different dengue serotypes

中华医学会第十三次全国精神医学学术会议

作者：王瑜王建 alexandra.m.murray Anne-Toussaint 董再全陈靓黄明金莫丽玲刘阳余建英罗珊霞郭万军陈然姜愚殷文蓉张岚四川大学华西医院心理卫生中心 Department of Psychosomatic medicine and Psychotherapy University Medical Center Hamburg-Eppendorf and Schon Clinic Hamburg Eilbek 四川大学华西医院肿瘤科

目的为了解医生和住院患者对心理问题的识别、识别的差异及影响识别一致性的相关人口学因素。方法我们对四川大学华西医院肿瘤科、心脏内科、甲乳外科、肝脏外科等10个科室的1 662名住院患者进行时点调查研究。问卷包括患者和医生的基... 详细信息

目的为了解医生和住院患者对心理问题的识别、识别的差异及影响识别一致性的相关人口学因素。方法我们对四川大学华西医院肿瘤科、心脏内科、甲乳外科、肝脏外科等10个科室的1 662名住院患者进行时点调查研究。问卷包括患者和医生的基本人口学资料,患者健康问卷-9(PHQ-9)、焦虑问卷-7(GAD-7)、患者健康问卷-15(PHQ-15)、健康焦虑量表-7(Whiteley-7)四个量表及询问医生和患者对心理问题识别的两个问题。使用SPSS18.0分析处理数据,应用了描述性统计、卡方分析、Logistic回归等统计学方法。结果在1329份有效问卷中,大量患者(53.4%)共病心理问题,其中以抑郁(31.8%)最常见,但医生对心理问题的识别率(39.1%)和患者对自身心理问题的感知率(34.9%)均较低,且两者的一致性极差(Kappa=0.089,P=0.001)。影响其一致性的因素主要有患者的抑郁焦虑症状的临床显著性、家庭平均年收入、医生性别和工作经验。家庭年收入高的患者对心理问题的自我识别更容易同医生的识别一致;女医生、工作年限短的医生对心理问题的识别更容易同患者的自我感知一致。结论大量综合科室住院患者伴发有心理问题,然而医生对心理问题的识别率和患者的自我感知率均较低,且两者极低的一致性与患者的收入、医生的性别及工作经验有一定关系。因此,我们需要对非精神科医生进行更多的精神专科培训,同时提供其快速有效的心理筛查工具。

关键词：共病心理问题识别率医患差异

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Advances in Ophthalmology Practice and Research 2022年第2期2卷 18-24页

作者： Ajeet m.Wagle Smita R.Hegde Srinivasan Sanjay Kah-Guan Au Eong International Eye Cataract Retina Centre Mount Elizabeth Medical CentreSingapore International Eye Cataract Retina Centre Farrer Park Medical CentreSingapore Khoo Teck Puat Hospital Singapore alexandra Hospital Singapore Shree Shantinath medical Trust-Jain Hospital MumbaiIndia Narayana Nethralaya BangaloreIndia Lee Kong Chian School of medicine Nanyang Technological UniversitySingapore

Purpose:Dengue fever(DF)epidemics in Singapore in 2005–2006 and 2007 were caused predominantly by dengue virus serotypes 1(DENV-1)and 2(DENV-2)*** investigated the prevalence of ophthalmic manifestations during these consecutive ***:Seropositive DF patients admitted to the hospital during two separate dengue epidemics were enrolled from June 2005 to December ***,ophthalmic,and laboratory data were *** primary outcome measures were differences in ophthalmic and laboratory features across the two *** associated with increased risk of developing various DF-related ophthalmic manifestations were the secondary outcome ***:Of the 115 patients enrolled,109(94.7%;33 in 2005–2006 and 76 in 2007)completed the eye screening *** of patients were Chinese(65,59.6%)and males(81,74.3%).The mean age was 40.8 years(range,18–87).Colour vision impairment(12 vs 14[36.4%vs 18.7%];P?0.04),cotton wool spots(10 vs 3[30.3%vs 3.9%];Pmal liver function(mean alanine amino-transferase[150.2 U/L vs 68.28 U/L;P?0.001],mean aspartate amino-transferase[196.86 U/L vs 99.53 U/L;P?0.002],total protein[68.43 g/L vs 72.27 g/L;P?0.016],serum albumin[36.86 g/L vs 40.5 g/L;P?0.001])were noted more often in DF epidemics predominantly caused by DENV-1 compared to ***:A higher prevalence of colour vision impairment,cotton wool spots,bleeding diathesis,and abnormal liver function was found in DF epidemics predominantly caused by DENV-1 compared to DENV-2.

关键词： Dengue fever Ophthalmic manifestations Serotype Epidemic Singapore