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Evaluation of Malaria Transmission and Vector Control Strategies in the Dry Season in the Cotonou V Health Zone, Benin, West Africa

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Advances in Entomology 2023年第3期11卷 156-171页

作者： Tokponnon Filémon Osse Razaki Zannou Ahissou Robert Franck alapini marlène Sare Dabou Zoulkifilou Houessinon Festus Gounou Yerima Idayath Sominahoun André Akogbeto Martin Centre de Recherche Entomologique de Cotonou Cotonou République du Bénin Ecole Polytechnique d’Abomey-Calavi Université d’Abomey-Calavi Abomey-Calavi Republique du Bénin Ministère de la Santé Cotonou Republique du Bénin Cercle d’Action pour un Développement Durable ONG Abomey-Calavi Republique du Bénin Ecole de Gestion et d’Exploitation des Systèmes d’Elevage Université Nationale d’Agriculture Kétou Republique du Bénin

The anarchic urbanization of certain African cities favors the multiplication of the malaria parasite. Thus, the urgent mobilization of African cities is essential to combat this health risk. It is, therefore, with the objective of contributing to the investigation of problem areas that the present study evaluates malaria transmission and vector control strategies in the Cotonou V health zone in particular. This is a cross-sectional study taking into account four neighborhoods, including Wologuèdè, Sainte Rita, Gbèdjromèdé and the area around Etoile Rouge. Two nocturnal captures on voluntary humans and the method of spray were carried out in the dry season from December 2021 to February 2022. On the captured Anopheles, the ELISA Circum-Sporozoite Protein test was performed to determine the infectivity and calculate some transmission parameters. Finally, we conducted a survey using the second stage sampling method with one step to ask selected households about their knowledge of vector control methods, their use and the physical integrity of LLINs. We collected 2386 culicidae of which the majority was Culex quinquefasciatus. After the ELISA test, the 29 Anopheles tested, showed no infectivity, i.e. an EIR of 0 pi/h/n. In addition, 99% of the populations in the Cotonou V area use LLINs to protect themselves. However, coils, door and window screens, aerosol sprays, skin and household repellents, and periodic indoor spraying were used. Finally, the majority of nets observed had T1 tears, but there were also T2, T3 and T4 nets (P-value = 0.0). This study confirms that malaria transmission during the dry season in the Cotonou V health zone is almost negligible but not non-existent. Also, populations are exposed to the nuisance of Culex quinquefasciatus mosquitoes continuously throughout the year.

关键词： Anopheles Transmission Urban Malaria Cotonou V Health Zone Vector Control

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Evaluation of Malaria Transmission and Vector Control Strategies in the Dry Season in the Cotonou V Health Zone, Benin, West Africa

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Advances in Entomology（昆虫学） 2023年第3期

作者： Tokponnon Filémon Osse Razaki Zannou Ahissou Robert Franck alapini marlène Sare Dabou Zoulkifilou Houessinon Festus Gounou Yerima Idayath Sominahoun André Akogbeto Martin

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Crosstalk between androgen signaling and the chemokine receptor CXCR4:a novel strategy to promote myelin regeneration

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neural Regeneration Research 2025年第9期20卷 2581-2582页

作者： Marianne Bardy-Lagarde Narimène Asbelaoui Abdel Mouman Ghoumari UMR1195 “Diseases and Hormones of the Nervous System”Inserm and University Paris-SaclayKremlin-BicêtreFrance

Multiple sclerosis(MS)is the most common chronic disease of the central nervous system(CNS)in young adults and represents the first cause of severe handicap,originally non-traumatic(Oh et al.,2018).MS is chara cterized by the infiltration of auto reactive lymphocytes specific to myelin through the blood-brain barrier,which results in the appearance of inflammatory demyelinating lesions caused by the death of the central nervous system myelinating cells,oligodendrocytes(Oh et al.,2018).There is a prevalence sexual with a ratio of three times more affected women than men.

关键词： myelin al. CXCR4

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Intestinal glucagon-like peptide-1:A new player associated with impaired counterregulatory responses to hypoglycaemia in type 1 diabetic mice

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World Journal of Diabetes 2024年第8期15卷 1764-1777页

作者： Fang-Xin Jin Yan Wang Min-ne Li Ru-Jiang Li Jun-Tang Guo Department of Histology and Embryology Key Laboratory of Universities in Shandong ProvinceShandong Second Medical UniversityWeifang 261053Shandong ProvinceChina Department of Pathological Physiology Shandong Second Medical UniversityWeifang 261053Shandong ProvinceChina

BACKGROUND Impaired hypoglycaemic counterregulation has emerged as a critical concern for diabetic patients who may be hesitant to medically lower their blood glucose levels due to the fear of potential hypoglycaemic ***,the pathogenesis of hypoglycaemic counterregulation is still ***-like peptide-1(GLP-1)and its analogues have been used as adjunctive therapies for type 1 diabetes mellitus(T1DM).The role of GLP-1 in counterregulatory dysfunction during hypoglycaemia in patients with T1DM has not been *** To explore the impact of intestinal GLP-1 on impaired hypoglycaemic counterregulation in type 1 diabetic *** T1DM was induced in C57BL/6J mice using streptozotocin,followed by intraperitoneal insulin injections to create T1DM models with either a single episode of hypoglycaemia or recurrent episodes of hypoglycaemia(DH5).Immunofluorescence,Western blot,and enzyme-linked immunosorbent assay were employed to evaluate the influence of intestinal GLP-1 on the sympathetic-adrenal reflex and glucagon(GCG)*** GLP-1 receptor agonist GLP-1(7-36)or the antagonist exendin(9-39)were infused into the terminal ileum or injected intraperitoneally to further investigate the role of intestinal GLP-1 in hypoglycaemic counterregulation in the model *** The expression levels of intestinal GLP-1 and its receptor(GLP-1R)were significantly increased in DH5 *** instances of excess of intestinal GLP-1 weakens the sympathetic-adrenal reflex,leading to dysfunction of adrenal counterregulation during ***5 mice showed increased pancreaticδ-cell mass,cAMP levels inδcells,and plasma somatostatin concentrations,while cAMP levels in pancreaticαcells and plasma GCG levels ***,GLP-1R expression in islet cells and plasma active GLP-1 levels were significantly increased in the DH5 *** experiments involving terminal ileal infusion and intraperitoneal injection in the model mice demonstra

关键词： Glucagon-like peptide-1 Impaired hypoglycaemic counterregulation Type 1 diabetes Intestine Pancreas

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Direct Ni Electroless Metallization of Poly(etherimide) without Using Palladium as a Catalyst

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材料热处理学报 2004年第5B期25卷 1106-1111页

作者： marlène Charbonnier Maurice Romand Yves Goepfert Laboratoire de Sciences et Ingenierie des Surfaces Universite Claude Bernard - Lyon 1 69622 Villeurbanne Cedex FranceLaboratoire de Sciences et Ingenierie des Surfaces Universite Claude Bernard - Lyon 1 69622 Villeurbanne Cedex FranceUMR 5180 des Sciences Analytiques Universite Claude Bernard - Lyon 1 69622 Villeurbanne Cedex France

Nickel or copper electroless metallization of polymers needs the grafting of a catalyst (palladium in the Pd(0) oxidation state) on the substrate surface to be coated. Our previous works on this topic [1-5] have allowed to develop a simple, tin-free method to attach Pd(+2) species from a palladium chloride (PdCl2) solution on any insulating surface and subsequently to reduce them, in the wet way, into the Pd(0) oxidation state. This Pd(0) state of the catalyst allows an instantaneous initiation of the Ni or Cu deposit by immersion in a plating bath. As palladium is an expensive chemical, it appears interesting to replace it by Ni(0) or Cu(0) species which are catalysts of their own ion reduction. Concerning the direct Ni electroless plating, the polymer surface (PI) was made catalytic for the electroless process by deposition (spin- coating or dipping) of an ultra-thin film of an organic nickel salt in an alcoholic solution. The chemical reduction of this salt, checked by XPS, was performed by chemical or photochemical ways and by plasma. Under these conditions, the initiation, by autocatalysis, of the Ni film deposition in an industrial plating bath was immediate i.e. without any initiation time. The film obtained was homogeneous, dense, bright, well-adhering up to thicknesses reaching

关键词：镍非电金属喷镀等离子处理 XPS 聚酰亚胺

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Crosstalk between androgen signaling and the chemokine receptor CXCR4:a novel strategy to promote myelin regeneration

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neural Regeneration Research 2025年第09期 2581-2582页

作者： Marianne Bardy-Lagarde Narimène Asbelaoui Abdel Mouman Ghoumari UMR1195 "Diseases and Hormones of the Nervous System"Inserm and University Paris-Saclay

Multiple sclerosis(MS) is the most common chronic disease of the central nervous system(CNS) in young adults and represents the first cause of severe handicap,originally non-traumatic(Oh et al.,2018).MS is chara cterized by the infiltration of auto reactive lymphocytes specific to myelin through the blood-brain barrier,which results in the appearance of inflammatory demyelinating lesions caused by the death of the central nervous system myelinating cells,oligodendrocytes(Oh et al.,2018).There is a prevalence sexual with a ratio of three times more affected women than men.

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How to derive a geovisualization from an application data model: an approach based on Semantic Web technologies

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International Journal of Digital Earth 2021年第7期14卷 874-898页

作者： Matthieu Viry marlène Villanova-Oliver Univ.Grenoble Alpes CNRSGrenoble INP(Institute of Engineering Univ.Grenoble Alpes)LIGGrenobleFrance

While ontological modelling and Semantic Web technologies are sometimes used to describe knowledge domains with a spatial component,there is still a lack of semantics to describe how to present this knowledge geovisually to the end user and how to automatize the *** this paper,we first present vocabularies to describe at a high level the elements that make up a *** then propose a method that describes at a semantic level how to obtain a geovisualization from an existing data *** method is based on our vocabularies and on a set of semantic rules encoding rich and complex operations on *** leads to the derivation of ontological knowledge,ready to be exploited to automate the creation of a *** method is implemented in a framework that uses Semantic Web *** singularity and the strength of our proposal is that it enables to describe a geovisualization through a RDF specification file,which once loaded in our system makes the geovisualization directly available for use from a Web *** result is obtained by extending a priori an application data model with ad hoc geovisualization semantics features and rules.

关键词： Knowledge representation Semantic Web geovisualization ontologies rule-based system

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The Life and Political Leadership of Gra?a Machel

心理传记与质性心理学

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心理传记与质性心理学 2024年第1期 126-154页

作者： Claude-Hélène Mayer University of Johannesburg South Africa

This article focuses on the life and political leadership of an extraordinary woman leader, Gra?a Machel. Gra?a Machel was born in very poor circumstances in rural Mozambique, became a fighter against colonialism, and married to Presidents: firstly, she married Samora Machel, later she married nelson Mandela. At the same time, she followed her own political career, always promoting a political agenda of education, peace and distribution of wealth. Her political leadership is an extraordinary example for leaders in Southern Africa and the world. This psychobiography contributes to expanding the psychobiographies on extraordinary women in political leadership in Southern Africa. Its aim is to present new insights into the life of Gra?a Machel and her political leadership as a woman leader in pan-African contexts from a psychobio-graphical perspective.

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Effects of Prandtl and Jacob Numbers and Dimensionless Thermal Conductivity on Velocity Profiles in Media (Porous and Liquid)

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Journal of Modern Physics 2024年第10期15卷 1603-1614页

作者： Momath Ndiaye Madialène Sene Goumbo Ndiaye Department of Hydraulics Rural Engineering Machinery and Renewable Energy UFR Fundamental and Engineering Sciences University of Sine Saloum El Hadj Ibrahima NIASS Kaolack Senegal

In this present study, we analyzed the effects of Prandtl and Jacob numbers and dimensionless thermal conductivity on the velocity profiles in media (porous and liquid). The transfers in the porous medium and the liquid film are described respectively by the improved Wooding model and the classical boundary layer equations. The mesh of the digital domain is considered uniform in the transverse and longitudinal directions. The advection and diffusion terms are discretized with a back-centered and centered scheme respectively. The coupled systems of algebraic equations thus obtained are solved numerically using an iterative line-by-line relaxation method of the Gauss-Seidel type. The results show that the parameters relating to the thermal problem (the dimensionless thermal conductivity, the Prandtl (Pr) and Jacob (Ja) numbers) have no influence on the dimensionless speed, although the thermal and hydrodynamic problems are coupled. Via the heat balance equation. The results obtained show that the parameters relating to the thermal problem have no influence on the dimensionless speed, although the thermal and hydrodynamic problems are coupled via the heat balance equation. So, at first approximation with the chosen constants, we can solve the hydrodynamic problem independently of the thermal problem.

关键词： Condensation Implicit Finite Difference Thin Film Porous Material Model Wooding Vertical Wall

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Immunotoxic potential of aeration lagoon effluents for the treatment of domestic and hospital wastewaters in the freshwater mussel Elliptio complanata

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Journal of Environmental Sciences 2012年第5期24卷 781-789页

作者： Francois Gagné Chantale André marlène Fortier Michel Fournier Fluvial Ecosystem Research Environment Canada Montréal Quebec H2Y 2E7 Canada INRS-Institut Armand-Frappier Laval Québec Canada

Municipal wastewaters are major sources of pollution for the aquatic biota. The purpose of this study was to determine the levels of some pharmaceutical products and the immunotoxic potential of a municipal wastewater aeration lagoon for the treatment of the domestic wastewaters of a small town with wastewater inputs from a 400-bed hospital complex. Endemic mussels were collected, caged and placed in the final aeration lagoon and at sites 1 km upstream and 1 km downstream of the effluent outfall in the receiving river for a period of 14 days. The results showed that the final aeration lagoon contained high levels of total coliforms, conductivity and low dissolved oxygen （2.9 mg/L） as well as detectable amounts of trimethoprim, carbamazepine, gemfibrozil, and norfloxacin at concentrations exceeding 50 ng/L. The lagoon effluent was indeed toxic to the mussel specimens, as evidenced by the appearance of mortality after 14 days （10% mortality）, decreased mussel weight-to-shell-length ratio and loss of hemocyte viability. The number of adhering hemocytes, phagocytic activity, total nitrite levels and arachidonic cyclooxygenase activity were significantly higher in mussels placed in the final aeration lagoon. A multivariate analysis also revealed that water pH, conductivity, total coliforms and dissolved oxygen were the endpoints most closely linked with phagocytic activity, the amount of adhering hemocytes and loss of hemocyte viability. In conclusion, exposure of mussels to treated aerated lagoon wastewater is deleterious to freshwater mussels where the immune system is compromised.

关键词： mussels municipal wastewaters immunocompetence inflammation cyclooxygenase activity

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