Crosstalk between androgen signaling and the chemokine receptor CXCR4:a novel strategy to promote myelin regeneration

作     者：Marianne Bardy-Lagarde Narimène Asbelaoui Abdel Mouman Ghoumari 

作者机构：UMR1195"Diseases and Hormones of the Nervous System"Inserm and University Paris-Saclay 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究(英文))

年 卷 期：2025年第09期

页      面：2581-2582页

核心收录：

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

基　　金：supported by a grant from the French Multiple Sclerosis Society (ARSEP Grant Number:R20163LL)(to AMG) 

摘      要：Multiple sclerosis(MS) is the most common chronic disease of the central nervous system(CNS) in young adults and represents the first cause of severe handicap,originally non-traumatic(Oh et al.,2018).MS is chara cterized by the infiltration of auto reactive lymphocytes specific to myelin through the blood-brain barrier,which results in the appearance of inflammatory demyelinating lesions caused by the death of the central nervous system myelinating cells,oligodendrocytes(Oh et al.,2018).There is a prevalence sexual with a ratio of three times more affected women than men.